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ARVO Annual Meeting Abstract June 2022

Erucamide targets microglia to regulate the retinal angiogenic microenvironment and function as a neurotrophic factor

GUOQIN WEI; Shreyosree Chatterjee; Sanahan Vijayakumar; Daisuke Ogasawara; Yoichiro Ideguchi; Edith Aguilar; Sarah Giles; Dale Boger; Benjamin Cravatt; Michael J Sailor; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):273 – F0318. doi:

ARVO Annual Meeting Abstract June 2022

The serine biosynthetic enzyme, PHGDH, is essential for retinal health

Marin Gantner; Regis Fallon; Yoichiro Ideguchi; Caleb Bates; Michal Handzlik; Martina Wallace; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):870. doi:

ARVO Annual Meeting Abstract June 2022

Reducing serine and glycine leads to impaired RPE phagocytosis

Caleb Bates; Regis Fallon; Yoichiro Ideguchi; Andrew Greer; Martin Friedlander; Marin Gantner

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2489 – F0196. doi:

ARVO Annual Meeting Abstract June 2022

Patient iPSC-RPE implicate mitochondrial defects in Macular Telangiectasia

Sarah Giles; Brendan Ansell; Sarah Harkins-Perry; Martina Wallace; Marin Gantner; Regis Fallon; Alec Johnson; Barbara Hart; Melanie Bahlo; Rando Allikmets; Christian Metallo; Paul S Bernstein; Martin Friedlander; Kevin Thomas Eade

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2449 – F0393. doi:

ARVO Annual Meeting Abstract June 2022

Deoxysphingolipids mediate toxicity though the Unfolded Protein Response (UPR)

Kevin Thomas Eade; Jessica Rosarda; Sarah Giles; Sarah Harkins-Perry; R. Luke Wiseman; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2436 – F0380. doi:

ARVO Annual Meeting Abstract June 2022

New co-culture system of human iPSC induced retinal organoid and microglia

Ayumi Ouchi; Sarah Giles; Nobuyuki Ebihara; Kevin Thomas Eade; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3723 – F0329. doi:

ARVO Annual Meeting Abstract June 2022

Application of deep learning to quantify vascular tortuosity in mouse models of oxygen-induced retinopathy

Kyle Vincent Marra; Jimmy S Chen; Hailey Robles-Holmes; Kristine Ly; Joseph Miller; Guoqin Wei; Edith Aguilar; Yoichiro Ideguchi; Sofia Prenner; Deniz Erdogmus; Peter Campbell; Martin Friedlander; Eric Nudleman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2070 – F0059. doi:

ARVO Annual Meeting Abstract June 2021

Differentially expressed microRNAs within extracellular vesicles of a functionally active subpopulation of endothelial colony forming cells demonstrate neurovasculotrophic effects

Kyle Vincent Marra; Edith Aguilar; Ayumi Ouchi; Guoqin Wei; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):221. doi:

ARVO Annual Meeting Abstract June 2021

Functional relevance of hyper-reflectivity in macular telangiectasia type 2 (MacTel)

Simone Tzaridis; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2205. doi:

Retina March 2021

Functional Relevance of Hyper-Reflectivity in Macular Telangiectasia Type 2

PDF

Simone Tzaridis; Martin Friedlander; for the Macular Telangiectasia Type 2-Phase 2 CNTF Research Group
TAGS: eye, ophthalmologists, telangiectasis
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):6. doi: https://doi.org/10.1167/iovs.62.3.6

Includes: Supplemental Content

Retinal Cell Biology August 2020

CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

PDF

Felicitas Bucher; Edith Aguilar; Kyle V. Marra; Julian Rapp; Jakob Arnold; Sophia Diaz-Aguilar; Clemens Lange; Hansjürgen Agostini; Günther Schlunck; Andreas Stahl; Martin Friedlander
TAGS: ciliary neurotrophic factor, retinal neovascularization, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):20. doi: https://doi.org/10.1167/iovs.61.10.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Optical coherence tomography angiography for treatment monitoring of neovascularizations secondary to macular telangiectasia type 2 (MacTel)

Simone Tzaridis; Kristina Hess; Martin Friedlander; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4808. doi:

ARVO Annual Meeting Abstract June 2020

CITED2 regulates hypoxia-induced retinal neovascularization in a mouse model of oxygen-induced retinopathy

Ayumi Ouchi; Rebecca B Berlow; Edith Aguilar; Yoichiro Ideguchi; GUOQIN WEI; Kyle Vincent Marra; Peter E Wright; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4930. doi:

ARVO Annual Meeting Abstract June 2020

Role of microglia in the formation of subretinal neovascularization in Vldlr -/ - mice

Edith Aguilar; Ayumi Ouchi; Yoshihiko Usui; Toshihide Kurihara; Michael Dorrell; Yoichiro Ideguchi; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5403. doi:

ARVO Annual Meeting Abstract June 2020

Deep learning-based automatic segmentation of retinal cavitations on OCT images of MacTel2

Jessica Loo; Cindy Xinji Cai; Emily Chew; Martin Friedlander; Glenn J Jaffe; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1616. doi:

ARVO Annual Meeting Abstract July 2019

Extracellular vesicles shed from endothelial colony forming cells (ECFCs) with high expression of CD44 are paracrine mediators of neurovasculotrophic retinal repair

Kyle Vincent Marra; Edith Aguilar; Ayumi Ouchi; Susumu Sakimoto; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6389. doi:

ARVO Annual Meeting Abstract July 2019

Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment

Jessica Loo; Traci E Clemons; Emily Y Chew; Martin Friedlander; Glenn J Jaffe; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1449. doi:

ARVO Annual Meeting Abstract July 2019

A xeno-free culture system for efficient derivation and amplification of human endothelial colony-forming cells from umbilical cord blood

valentina marchetti; Kelsey Lee; Ravenska Wagey; Carrie Peters; Susumu Sakimoto; Edith Aguilar; Martin Friedlander; Terry Thomas; Allen Eaves; Stephen Szilvassy; Sharon Louis

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2730. doi:

ARVO Annual Meeting Abstract July 2019

Reduced serine synthesis in patient-derived retinal pigmented epithelium leads to localized lipid dysfunction in MacTel

Kevin Eade; sarah giles; Sarah Harkins-Perry; Regis Fallon; Marin Gantner; michelle baldini; Martina Wallace; Rando Allikmets; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3852. doi:

ARVO Annual Meeting Abstract July 2019

Reduced systemic serine levels lead to retinal defects in a mouse model of MacTel

Marin Gantner; Martina Wallace; Regis Fallon; Michal Handzlik; Kevin Eade; Ilham Polis; Alex Ideguchi; Maki Kitano; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4954. doi:

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Erucamide targets microglia to regulate the retinal angiogenic microenvironment and function as a neurotrophic factor

The serine biosynthetic enzyme, PHGDH, is essential for retinal health

Reducing serine and glycine leads to impaired RPE phagocytosis

Patient iPSC-RPE implicate mitochondrial defects in Macular Telangiectasia

Deoxysphingolipids mediate toxicity though the Unfolded Protein Response (UPR)

New co-culture system of human iPSC induced retinal organoid and microglia

Application of deep learning to quantify vascular tortuosity in mouse models of oxygen-induced retinopathy

Differentially expressed microRNAs within extracellular vesicles of a functionally active subpopulation of endothelial colony forming cells demonstrate neurovasculotrophic effects

Functional relevance of hyper-reflectivity in macular telangiectasia type 2 (MacTel)

Functional Relevance of Hyper-Reflectivity in Macular Telangiectasia Type 2

CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

Optical coherence tomography angiography for treatment monitoring of neovascularizations secondary to macular telangiectasia type 2 (MacTel)

CITED2 regulates hypoxia-induced retinal neovascularization in a mouse model of oxygen-induced retinopathy

Role of microglia in the formation of subretinal neovascularization in Vldlr -/ - mice

Deep learning-based automatic segmentation of retinal cavitations on OCT images of MacTel2

Extracellular vesicles shed from endothelial colony forming cells (ECFCs) with high expression of CD44 are paracrine mediators of neurovasculotrophic retinal repair

Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment

A xeno-free culture system for efficient derivation and amplification of human endothelial colony-forming cells from umbilical cord blood

Reduced serine synthesis in patient-derived retinal pigmented epithelium leads to localized lipid dysfunction in MacTel

Reduced systemic serine levels lead to retinal defects in a mouse model of MacTel

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