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ARVO Annual Meeting Abstract July 2019

Reduced serine synthesis in patient-derived retinal pigmented epithelium leads to localized lipid dysfunction in MacTel

Kevin Eade; sarah giles; Sarah Harkins-Perry; Regis Fallon; Marin Gantner; michelle baldini; Martina Wallace; Rando Allikmets; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3852. doi:

ARVO Annual Meeting Abstract July 2019

Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment

Jessica Loo; Traci E Clemons; Emily Y Chew; Martin Friedlander; Glenn J Jaffe; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1449. doi:

ARVO Annual Meeting Abstract July 2019

A xeno-free culture system for efficient derivation and amplification of human endothelial colony-forming cells from umbilical cord blood

valentina marchetti; Kelsey Lee; Ravenska Wagey; Carrie Peters; Susumu Sakimoto; Edith Aguilar; Martin Friedlander; Terry Thomas; Allen Eaves; Stephen Szilvassy; Sharon Louis

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2730. doi:

ARVO Annual Meeting Abstract July 2019

Reduced systemic serine levels lead to retinal defects in a mouse model of MacTel

Marin Gantner; Martina Wallace; Regis Fallon; Michal Handzlik; Kevin Eade; Ilham Polis; Alex Ideguchi; Maki Kitano; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4954. doi:

ARVO Annual Meeting Abstract July 2019

The role of Acid-sensing ion channel 1a in a mouse model of ischemic retinopathy.

Ayumi Ouchi; Edith Aguilar; Kyle Vincent Marra; Min Qiang; Yang Guang; Richard Lerner; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5739. doi:

ARVO Annual Meeting Abstract July 2019

Extracellular vesicles shed from endothelial colony forming cells (ECFCs) with high expression of CD44 are paracrine mediators of neurovasculotrophic retinal repair

Kyle Vincent Marra; Edith Aguilar; Ayumi Ouchi; Susumu Sakimoto; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6389. doi:

ARVO Annual Meeting Abstract July 2019

MacTel patients carry rare phosphoglycerate dehydrogenase (PHGDH) variants with reduced enzymatic activity

Regis Fallon; Rebecca Berlow; Jana Zernant; Takayuki Nagasaki; Marin Gantner; Sarah Harkins-Perry; Kevin Eade; Rando Allikmets; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5994. doi:

ARVO Annual Meeting Abstract July 2018

Web based, fully automated, deep learning segmentation of oxygen induced retinopathy

Sa Xiao; Felicitas Bucher; yue wu; Ariel Rokem; Cecilia S Lee; Kyle V Marra; Regis Fallon; Sophia Diaz-Aguilar; Edith Aguilar; Martin Friedlander; Aaron Y. Lee

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1223. doi:

ARVO Annual Meeting Abstract July 2018

Phase 2 Trial of Ciliary Neurotrophic Factor for Macular Telangiectasia Type 2

Emily Y. Chew; Traci E Clemons; Glenn J Jaffe; Sina Farsiu; eleonora lad; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2605. doi:

ARVO Annual Meeting Abstract July 2018

Modeling the cell specific origins of MacTel using a large patient iPSC-RPE library

Kevin Eade; Marin Gantner; sarah Victor; Regis Fallon; sarah harkins-perry; Alec Johnson; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4584. doi:

ARVO Annual Meeting Abstract July 2018

CxCl10 mediates CNTF inhibition of outer retinal neovascularization

Felicitas Bucher; Edith Aguilar; Kyle V Marra; Andreas Stahl; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5327. doi:

ARVO Annual Meeting Abstract July 2018

Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity

Regis Fallon; Jana Zernant; Takayuki Nagasaki; Marin Gantner; sarah harkins-perry; Kevin Eade; Rando Allikmets; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5409. doi:

ARVO Annual Meeting Abstract July 2018

Extracellular vesicles from endothelial colony forming cells as paracrine mediators of neurovasculotrophic repair of the retina

Kyle V Marra; Susumu Sakimoto; Salome Murinello; Edith Aguilar; Felicitas Bucher; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5489. doi:

ARVO Annual Meeting Abstract July 2018

Human Serum Metabolomics Study in Macular Telangiectasia Type 2

Sasha Woods; Michael Powner; Senthil Selvam; Kamron Khan; Robyn H Guymer; Jennifer Trombley; Catherine Egan; Martin Friedlander; Marcus Fruttiger

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3154. doi:

Special Issue September 2017

Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2

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Dibyendu Mukherjee; Eleonora M. Lad; Ryan R. Vann; Stephanie J. Jaffe; Traci E. Clemons; Martin Friedlander; Emily Y. Chew; Glenn J. Jaffe; Sina Farsiu; for the MacTel Study Group
TAGS: telangiectasis, diagnostic imaging, eye, optical coherence tomography, personal integrity, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO291-BIO299. doi: 10.1167/iovs.17-21834

ARVO Annual Meeting Abstract June 2017

CNTF treatment prevents development of pathological tuft formation in VLDLR -/- mice

Edith Aguilar; Felicitas Bucher; Mauricio Rosenfeld; Susumu Sakimoto; Salome Murinello; Marin Gantner; kevin eade; Sophia Diaz-Aguilar; Maki Kitano; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):189. doi:

ARVO Annual Meeting Abstract June 2017

Mitochondrial activity in the retina relies on glycolysis independent of substrate availability

Marin Gantner; kevin eade; Edith Aguilar; Mitchell Prins; Alec Johnson; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3013. doi:

ARVO Annual Meeting Abstract June 2017

Characterization of the neuroinflammatory response in the oxygen-induced retinopathy model of ischemic retinopathy

Kyle Marra; Salome Murinello; Felicitas Bucher; Edith Aguilar; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3462. doi:

ARVO Annual Meeting Abstract June 2017

MiR-30a-5p inhibition prevents neovascularization through CCL2 upregulation and microglia activation in a model of ischemic retinopathy

Salome Murinello; Yoshihiko Usui; Susumu Sakimoto; Maki Kitano; Edith Aguilar; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5383. doi:

ARVO Annual Meeting Abstract September 2016

Old player, new game: supplementing, rather than inhibiting, CCL2 may more effectively limit retinal neovascularization.

Salome Murinello; Peter D Westenskow; Edith Aguilar; Amelia Schrick; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3647. doi:

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Reduced serine synthesis in patient-derived retinal pigmented epithelium leads to localized lipid dysfunction in MacTel

Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment

A xeno-free culture system for efficient derivation and amplification of human endothelial colony-forming cells from umbilical cord blood

Reduced systemic serine levels lead to retinal defects in a mouse model of MacTel

The role of Acid-sensing ion channel 1a in a mouse model of ischemic retinopathy.

Extracellular vesicles shed from endothelial colony forming cells (ECFCs) with high expression of CD44 are paracrine mediators of neurovasculotrophic retinal repair

MacTel patients carry rare phosphoglycerate dehydrogenase (PHGDH) variants with reduced enzymatic activity

Web based, fully automated, deep learning segmentation of oxygen induced retinopathy

Phase 2 Trial of Ciliary Neurotrophic Factor for Macular Telangiectasia Type 2

Modeling the cell specific origins of MacTel using a large patient iPSC-RPE library

CxCl10 mediates CNTF inhibition of outer retinal neovascularization

Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity

Extracellular vesicles from endothelial colony forming cells as paracrine mediators of neurovasculotrophic repair of the retina

Human Serum Metabolomics Study in Macular Telangiectasia Type 2

Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2

CNTF treatment prevents development of pathological tuft formation in VLDLR -/- mice

Mitochondrial activity in the retina relies on glycolysis independent of substrate availability

Characterization of the neuroinflammatory response in the oxygen-induced retinopathy model of ischemic retinopathy

MiR-30a-5p inhibition prevents neovascularization through CCL2 upregulation and microglia activation in a model of ischemic retinopathy

Old player, new game: supplementing, rather than inhibiting, CCL2 may more effectively limit retinal neovascularization.

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