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Retinal Cell Biology August 2020

CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

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Felicitas Bucher; Edith Aguilar; Kyle V. Marra; Julian Rapp; Jakob Arnold; Sophia Diaz-Aguilar; Clemens Lange; Hansjürgen Agostini; Günther Schlunck; Andreas Stahl; Martin Friedlander
TAGS: ciliary neurotrophic factor, retinal neovascularization, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):20. doi: https://doi.org/10.1167/iovs.61.10.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Role of microglia in the formation of subretinal neovascularization in Vldlr -/ - mice

Edith Aguilar; Ayumi Ouchi; Yoshihiko Usui; Toshihide Kurihara; Michael Dorrell; Yoichiro Ideguchi; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5403. doi:

ARVO Annual Meeting Abstract June 2020

Deep learning-based automatic segmentation of retinal cavitations on OCT images of MacTel2

Jessica Loo; Cindy Xinji Cai; Emily Chew; Martin Friedlander; Glenn J Jaffe; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1616. doi:

ARVO Annual Meeting Abstract June 2020

Optical coherence tomography angiography for treatment monitoring of neovascularizations secondary to macular telangiectasia type 2 (MacTel)

Simone Tzaridis; Kristina Hess; Martin Friedlander; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4808. doi:

ARVO Annual Meeting Abstract June 2020

CITED2 regulates hypoxia-induced retinal neovascularization in a mouse model of oxygen-induced retinopathy

Ayumi Ouchi; Rebecca B Berlow; Edith Aguilar; Yoichiro Ideguchi; GUOQIN WEI; Kyle Vincent Marra; Peter E Wright; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4930. doi:

ARVO Annual Meeting Abstract July 2019

The role of Acid-sensing ion channel 1a in a mouse model of ischemic retinopathy.

Ayumi Ouchi; Edith Aguilar; Kyle Vincent Marra; Min Qiang; Yang Guang; Richard Lerner; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5739. doi:

ARVO Annual Meeting Abstract July 2019

MacTel patients carry rare phosphoglycerate dehydrogenase (PHGDH) variants with reduced enzymatic activity

Regis Fallon; Rebecca Berlow; Jana Zernant; Takayuki Nagasaki; Marin Gantner; Sarah Harkins-Perry; Kevin Eade; Rando Allikmets; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5994. doi:

ARVO Annual Meeting Abstract July 2019

Extracellular vesicles shed from endothelial colony forming cells (ECFCs) with high expression of CD44 are paracrine mediators of neurovasculotrophic retinal repair

Kyle Vincent Marra; Edith Aguilar; Ayumi Ouchi; Susumu Sakimoto; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6389. doi:

ARVO Annual Meeting Abstract July 2019

Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment

Jessica Loo; Traci E Clemons; Emily Y Chew; Martin Friedlander; Glenn J Jaffe; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1449. doi:

ARVO Annual Meeting Abstract July 2019

A xeno-free culture system for efficient derivation and amplification of human endothelial colony-forming cells from umbilical cord blood

valentina marchetti; Kelsey Lee; Ravenska Wagey; Carrie Peters; Susumu Sakimoto; Edith Aguilar; Martin Friedlander; Terry Thomas; Allen Eaves; Stephen Szilvassy; Sharon Louis

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2730. doi:

ARVO Annual Meeting Abstract July 2019

Reduced serine synthesis in patient-derived retinal pigmented epithelium leads to localized lipid dysfunction in MacTel

Kevin Eade; sarah giles; Sarah Harkins-Perry; Regis Fallon; Marin Gantner; michelle baldini; Martina Wallace; Rando Allikmets; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3852. doi:

ARVO Annual Meeting Abstract July 2019

Reduced systemic serine levels lead to retinal defects in a mouse model of MacTel

Marin Gantner; Martina Wallace; Regis Fallon; Michal Handzlik; Kevin Eade; Ilham Polis; Alex Ideguchi; Maki Kitano; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4954. doi:

ARVO Annual Meeting Abstract July 2018

Phase 2 Trial of Ciliary Neurotrophic Factor for Macular Telangiectasia Type 2

Emily Y. Chew; Traci E Clemons; Glenn J Jaffe; Sina Farsiu; eleonora lad; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2605. doi:

ARVO Annual Meeting Abstract July 2018

Human Serum Metabolomics Study in Macular Telangiectasia Type 2

Sasha Woods; Michael Powner; Senthil Selvam; Kamron Khan; Robyn H Guymer; Jennifer Trombley; Catherine Egan; Martin Friedlander; Marcus Fruttiger

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3154. doi:

ARVO Annual Meeting Abstract July 2018

Modeling the cell specific origins of MacTel using a large patient iPSC-RPE library

Kevin Eade; Marin Gantner; sarah Victor; Regis Fallon; sarah harkins-perry; Alec Johnson; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4584. doi:

ARVO Annual Meeting Abstract July 2018

CxCl10 mediates CNTF inhibition of outer retinal neovascularization

Felicitas Bucher; Edith Aguilar; Kyle V Marra; Andreas Stahl; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5327. doi:

ARVO Annual Meeting Abstract July 2018

Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity

Regis Fallon; Jana Zernant; Takayuki Nagasaki; Marin Gantner; sarah harkins-perry; Kevin Eade; Rando Allikmets; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5409. doi:

ARVO Annual Meeting Abstract July 2018

Extracellular vesicles from endothelial colony forming cells as paracrine mediators of neurovasculotrophic repair of the retina

Kyle V Marra; Susumu Sakimoto; Salome Murinello; Edith Aguilar; Felicitas Bucher; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5489. doi:

ARVO Annual Meeting Abstract July 2018

Web based, fully automated, deep learning segmentation of oxygen induced retinopathy

Sa Xiao; Felicitas Bucher; yue wu; Ariel Rokem; Cecilia S Lee; Kyle V Marra; Regis Fallon; Sophia Diaz-Aguilar; Edith Aguilar; Martin Friedlander; Aaron Y. Lee

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1223. doi:

Special Issue September 2017

Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2

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Dibyendu Mukherjee; Eleonora M. Lad; Ryan R. Vann; Stephanie J. Jaffe; Traci E. Clemons; Martin Friedlander; Emily Y. Chew; Glenn J. Jaffe; Sina Farsiu; for the MacTel Study Group
TAGS: diagnostic imaging, eye, optical coherence tomography, personal integrity, telangiectasis, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO291-BIO299. doi: https://doi.org/10.1167/iovs.17-21834

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CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

Role of microglia in the formation of subretinal neovascularization in Vldlr -/ - mice

Deep learning-based automatic segmentation of retinal cavitations on OCT images of MacTel2

Optical coherence tomography angiography for treatment monitoring of neovascularizations secondary to macular telangiectasia type 2 (MacTel)

CITED2 regulates hypoxia-induced retinal neovascularization in a mouse model of oxygen-induced retinopathy

The role of Acid-sensing ion channel 1a in a mouse model of ischemic retinopathy.

MacTel patients carry rare phosphoglycerate dehydrogenase (PHGDH) variants with reduced enzymatic activity

Extracellular vesicles shed from endothelial colony forming cells (ECFCs) with high expression of CD44 are paracrine mediators of neurovasculotrophic retinal repair

Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment

A xeno-free culture system for efficient derivation and amplification of human endothelial colony-forming cells from umbilical cord blood

Reduced serine synthesis in patient-derived retinal pigmented epithelium leads to localized lipid dysfunction in MacTel

Reduced systemic serine levels lead to retinal defects in a mouse model of MacTel

Phase 2 Trial of Ciliary Neurotrophic Factor for Macular Telangiectasia Type 2

Human Serum Metabolomics Study in Macular Telangiectasia Type 2

Modeling the cell specific origins of MacTel using a large patient iPSC-RPE library

CxCl10 mediates CNTF inhibition of outer retinal neovascularization

Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity

Extracellular vesicles from endothelial colony forming cells as paracrine mediators of neurovasculotrophic repair of the retina

Web based, fully automated, deep learning segmentation of oxygen induced retinopathy

Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2

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