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Articles November 2018

Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma

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Ian Pitha; Ericka Oglesby; Amanda Chow; Elizabeth Kimball; Mary Ellen Pease; Julie Schaub; Harry Quigley
TAGS: fibroblasts, glaucoma, collagen, patient isolation, phosphotransferases, transforming growth factors, eye, intraocular pressure, sclera, myofibroblasts
Trans. Vis. Sci. Tech.. 2018; 7(6):6. doi: 10.1167/tvst.7.6.6

Includes: Supplemental Content

Glaucoma October 2018

Age-Related Changes in Quantitative Strain of Mouse Astrocytic Lamina Cribrosa and Peripapillary Sclera Using Confocal Microscopy in an Explant Model

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Cathy Nguyen; Dan Midgett; Elizabeth Kimball; Joan Jefferys; Thao D. Nguyen; Julie Schaub; Mary Pease; Harry Quigley
TAGS: astrocytes, neurons, eye, mice, sclera, microscopy, confocal, cribriform plate
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5157-5166. doi: 10.1167/iovs.18-25111

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Structural Characterization of Human Lamina Cribrosa and Its Correlation to IOP-induced Strain

Yik Tung Tracy Ling; Ran shi; Dan Midgett; Cathy Nguyen; Elizabeth Cone-Kimball; Mary Pease; Harry A Quigley; Thao D Nguyen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1219. doi:

ARVO Annual Meeting Abstract July 2018

RHO-kinase-mediated regulation of myofibroblast differentiation in scleral fibroblasts during experimental glaucoma

Ian F Pitha; Ericka Oglesby; Elizabeth Cone-Kimball; Julie Schaub; Mary Pease; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6038. doi:

Articles March 2018

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

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Ian Pitha; Elizabeth C. Kimball; Ericka N. Oglesby; Mary Ellen Pease; Jie Fu; Julie Schaub; Yoo-Chun Kim; Qi Hu; Justin Hanes; Harry A. Quigley
TAGS: glaucoma, injection of therapeutic agent, retinal ganglion cells, eye, intraocular pressure, dorzolamide, eyedrops, cell-derived microparticles
Trans. Vis. Sci. Tech.. 2018; 7(2):13. doi: 10.1167/tvst.7.2.13

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Lack of regional axon loss in a murine glaucoma model

Julie Schaub; Elizabeth Cone-Kimball; Mary Ellen Pease; Ericka Oglesby; Cathy Nguyen; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2554. doi:

ARVO Annual Meeting Abstract June 2017

Mitochondrial movement and density in mouse ocular explant model after experimental glaucoma

Elizabeth Cone-Kimball; Mary Ellen Pease; Julie Schaub; Ericka Oglesby; Ian Pitha; Cathy Nguyen; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4606. doi:

ARVO Annual Meeting Abstract June 2017

Quantitative measures of alteration in the astrocytic lamina of mouse optic nerve head with experimental glaucoma

Yik Tung Tracy Ling; Cathy Nguyen; Elizabeth Cone-Kimball; Mary Ellen Pease; Harry A Quigley; Thao D Nguyen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3169. doi:

ARVO Annual Meeting Abstract June 2017

Sustained dorzolamide release prevents axonal and retinal ganglion cell loss in a rat model of IOP-glaucoma

Ian Pitha; Elizabeth Cone-Kimball; Ericka Oglesby; Mary Ellen Pease; Jie Fu; Yoo-Chun Kim; Julie Schaub; Qi Hu; Justin Hanes; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):853. doi:

ARVO Annual Meeting Abstract June 2017

Losartan inhibits myofibroblast transdifferentiation of human scleral fibroblasts

Ericka Oglesby; Julie Schaub; Elizabeth Cone-Kimball; Mary Ellen Pease; Ian Pitha; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4604. doi:

Glaucoma May 2017

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

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Julie A. Schaub; Elizabeth C. Kimball; Matthew R. Steinhart; Cathy Nguyen; Mary E. Pease; Ericka N. Oglesby; Joan L. Jefferys; Harry A. Quigley
TAGS: glaucoma, axon, retinal ganglion cells, eye, intraocular pressure, mice
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2765-2773. doi: 10.1167/iovs.17-21761

Includes: Supplemental Content

Glaucoma February 2017

Measuring Deformation in the Mouse Optic Nerve Head and Peripapillary Sclera

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Cathy Nguyen; Dan Midgett; Elizabeth C. Kimball; Matthew R. Steinhart; Thao D. Nguyen; Mary E. Pease; Ericka N. Oglesby; Joan L. Jefferys; Harry A. Quigley
TAGS: astrocytes, optic disk, eye, intraocular pressure, mice, sclera
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):721-733. doi: 10.1167/iovs.16-20620

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract September 2016

Regional Variations in the Strains of the Human Optic Nerve Head

Dan Midgett; Thao D Nguyen; Harry A Quigley; Mary Ellen Pease; Christian Franck; Mohak Patel

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3564. doi:

ARVO Annual Meeting Abstract September 2016

A new ocular explant model to study living optic nerve head events in experimental mouse glaucoma

Elizabeth Cone Kimball; Mary Ellen Pease; Matthew Steinhart; Ericka N Oglesby; Cathy Nguyen; Ian F Pitha; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):389. doi:

ARVO Annual Meeting Abstract June 2015

Inflation Test of Human Optic Nerve Head using Digital Volume Correlation

Dan E Midgett; Mary Ellen Pease; Harry A Quigley; Thao D Nguyen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):6145. doi:

Glaucoma October 2014

Changes in Scleral Collagen Organization in Murine Chronic Experimental Glaucoma

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Jacek K. Pijanka; Elizabeth C. Kimball; Mary E. Pease; Ahmed Abass; Thomas Sorensen; Thao D. Nguyen; Harry A. Quigley; Craig Boote
TAGS: diagnostic radiologic examination, roentgen rays, glaucoma, anisotropy, collagen, eye, intraocular pressure, mice, sclera, fibril
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6554-6564. doi: 10.1167/iovs.14-15047

ARVO Annual Meeting Abstract April 2014

Molecular and Cellular Changes of Scleral Fibroblasts after Exposure to Experimental Glaucoma in Mice

Ericka Oglesby; Gulgun Tezel; Elizabeth Cone-Kimball; Matthew R Steinhart; Joan Jefferys; Mary Ellen Pease; Harry Quigley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5693. doi:

ARVO Annual Meeting Abstract April 2014

Age Effect on Glaucoma Susceptibility: CD1 vs B6

Matthew Steinhart; Elizabeth Cone-Kimball; Cathy Nguyen; Thao D Nguyen; Mary Ellen Pease; Shukti Chakravarti; Ericka Oglesby; Harry Quigley; Glaucoma Center of Excellence

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3818. doi:

ARVO Annual Meeting Abstract April 2014

Confocal Microscopic Analysis of Lamina Cribrosa Displacement in Porcine and Human Eyes

Elizabeth Cone Kimball; Thao D Nguyen; Mary Ellen Pease; Dan Midgett; Harry Quigley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4251. doi:

ARVO Annual Meeting Abstract April 2014

Experimental scleral cross-linking increases glaucoma damage in a mouse model

Harry Quigley; Elizabeth Cone-Kimball; Cathy Nguyen; Matthew Steinhart; Mary Ellen Pease; Ericka Oglesby; Thao D Nguyen

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1665. doi:

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Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma

Age-Related Changes in Quantitative Strain of Mouse Astrocytic Lamina Cribrosa and Peripapillary Sclera Using Confocal Microscopy in an Explant Model

Structural Characterization of Human Lamina Cribrosa and Its Correlation to IOP-induced Strain

RHO-kinase-mediated regulation of myofibroblast differentiation in scleral fibroblasts during experimental glaucoma

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

Lack of regional axon loss in a murine glaucoma model

Mitochondrial movement and density in mouse ocular explant model after experimental glaucoma

Quantitative measures of alteration in the astrocytic lamina of mouse optic nerve head with experimental glaucoma

Sustained dorzolamide release prevents axonal and retinal ganglion cell loss in a rat model of IOP-glaucoma

Losartan inhibits myofibroblast transdifferentiation of human scleral fibroblasts

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

Measuring Deformation in the Mouse Optic Nerve Head and Peripapillary Sclera

Regional Variations in the Strains of the Human Optic Nerve Head

A new ocular explant model to study living optic nerve head events in experimental mouse glaucoma

Inflation Test of Human Optic Nerve Head using Digital Volume Correlation

Changes in Scleral Collagen Organization in Murine Chronic Experimental Glaucoma

Molecular and Cellular Changes of Scleral Fibroblasts after Exposure to Experimental Glaucoma in Mice

Age Effect on Glaucoma Susceptibility: CD1 vs B6

Confocal Microscopic Analysis of Lamina Cribrosa Displacement in Porcine and Human Eyes

Experimental scleral cross-linking increases glaucoma damage in a mouse model

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