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Cornea June 2024

Dysregulation of the TCF4 Isoform in Corneal Endothelial Cells of Patients With Fuchs Endothelial Corneal Dystrophy

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Tetsuro Honda; Tatsuya Nakagawa; Taichi Yuasa; Yuichi Tokuda; Masakazu Nakano; Kei Tashiro; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Koji Yamamoto; Noriko Koizumi; Naoki Okumura
TAGS: hereditary corneal dystrophy, protein isoforms, rna-seq, exons, cornea, endothelial cells, endothelium, datasets
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):27. https://doi.org/10.1167/iovs.65.6.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Investigation of the TCF4 Aberrant Splicing in the Corneal Endothelial Cells of Patients with Fuchs Endothelial Corneal Dystrophy

Taichi Yuasa; Naoki Okumura; Tatsuya Nakagawa; Tetsuro Honda; Ayana Tateishi; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Yuichi Tokuda; Masakazu Nakano; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5814.

ARVO Annual Meeting Abstract June 2023

Investigation of the TCF4 Splicing and Isoform Expressions in the Corneal Endothelial Cells of Patients with Fuchs Endothelial Corneal Dystrophy

Tetsuro Honda; Naoki Okumura; Tatsuya Nakagawa; Ayana Tateishi; Koji Yamamoto; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E. Kruse; Yuichi Tokuda; Masakazu Nakano; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):OD23.

ARVO Annual Meeting Abstract June 2023

Identification of Sex-Biased Genes in the Human Corneal Endothelial Cells by using RNA Sequencing Analysis

Soichiro Inagaki; Naoki Okumura; Tatsuya Nakagawa; Ayana Tateishi; Yuya Komori; Naoya Hanada; Yuichi Tokuda; Masakazu Nakano; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):649.

ARVO Annual Meeting Abstract June 2023

RNA Sequencing Analysis of Corneal Endothelial Cells Derived from Fuchs Endothelial Corneal Dystrophy Patients with and without Trinucleotide Repeat Expansion in TCF4

Yoshiaki Toyokawa; Naoki Okumura; Tatsuya Nakagawa; Ayana Tateishi; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E. Kruse; Yuichi Tokuda; Masakazu Nakano; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):640.

ARVO Annual Meeting Abstract June 2022

Seasonal Variation of Intraocular Pressure in Non-Glaucomatous Subjects

Yoko Ikeda; Kazuhiko Mori; Morio Ueno; Kengo Yoshii; Masakazu Nakano; Yuko Maruyama; Kojiro Imai; Natsue Omi; Hiroki Mieno; Ryuichi Sato; Kei Tashiro; Shigeru Kinoshita; Chie Sotozono

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):152 – A0345.

ARVO Annual Meeting Abstract June 2022

RNA-Seq based transcriptome analysis of corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy

Tatsuya Nakagawa; Naoki Okumura; Yuya Komori; Naoya Hanada; Yuichi Tokuda; Masakazu Nakano; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2278.

ARVO Annual Meeting Abstract June 2021

Trend of continuous intraocular pressure decrease over a 20-year period in Japanese normal tension glaucoma patients

Yoko Ikeda; Kazuhiko Mori; Morio Ueno; Kengo Yoshii; Masakazu Nakano; Ryuichi Sato; Natsue Omi; Yuko Maruyama; Fumiko Sato; Kojiro Imai; Yuji Yamamoto; Toshihide Yamazaki; Kei Tashiro; Chie Sotozono; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1597.

Cornea December 2020

Mitochondria as a Platform for Dictating the Cell Fate of Cultured Human Corneal Endothelial Cells

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Kohsaku Numa; Morio Ueno; Tomoko Fujita; Koji Ueda; Nao Hiramoto; Atushi Mukai; Yuichi Tokuda; Masakazu Nakano; Chie Sotozono; Shigeru Kinoshita; Junji Hamuro

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):10. https://doi.org/10.1167/iovs.61.14.10

Includes: Supplemental Content

Physiology and Pharmacology May 2020

Polarized Expression of Ion Channels and Solute Carrier Family Transporters on Heterogeneous Cultured Human Corneal Endothelial Cells

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Junji Hamuro; Hideto Deguchi; Tomoko Fujita; Koji Ueda; Yuichi Tokuda; Nao Hiramoto; Kohsaku Numa; Masakazu Nakano; John Bush; Morio Ueno; Chie Sotozono; Shigeru Kinoshita
TAGS: cornea, endothelial cells, family, heterogeneity, ion channels, membrane transport proteins, slc transporters, solutes, proteins, metabolism
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):47. https://doi.org/10.1167/iovs.61.5.47

Includes: Supplemental Content

Cornea February 2020

Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells

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Junji Hamuro; Kohsaku Numa; Tomoko Fujita; Munetoyo Toda; Koji Ueda; Yuichi Tokuda; Atushi Mukai; Masakazu Nakano; Morio Ueno; Shigeru Kinoshita; Chie Sotozono
TAGS: cornea, endothelial cells, lactic acid, metabolites, pyruvic acid, small patella syndrome, sodium polystyrene sulfonate, stiff-person syndrome, enzymes
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):10. https://doi.org/10.1167/iovs.61.2.10

Includes: Supplemental Content

Cornea February 2019

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

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Naoki Okumura; Ryosuke Hayashi; Masakazu Nakano; Kengo Yoshii; Kei Tashiro; Takahiko Sato; Derek J. Blake; Ross Aleff; Malinda Butz; Edward W. Highsmith; Eric D. Wieben; Michael P. Fautsch; Keith H. Baratz; Yuya Komori; Makiko Nakahara; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi
TAGS: corneal endothelium, endothelium, hereditary corneal dystrophy, rna, messenger, trinucleotide repeat expansion, dna, genome, polymerase chain reaction, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):779-786. https://doi.org/10.1167/iovs.18-25760

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany

Yuya Komori; Naoki Okumura; Ryosuke Hayashi; Masakazu Nakano; Kei Tashiro; Kengo Yoshii; Ross Aleff; Malinda Butz; Edward W. Highsmith; Eric Wieben; Michael P. Fautsch; Keith H Baratz; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1353.

ARVO Annual Meeting Abstract June 2017

Expression level of the TCF4 gene in the corneal endothelium of Fuchs endothelial corneal dystrophy patients

Ryosuke Hayashi; Naoki Okumura; Keisuke Ogata; Masakazu Nakano; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1438.

ARVO Annual Meeting Abstract June 2017

Glaucoma prevalence over time in Japanese from Kyoto Glaucoma Screening Cohort

Yoko Ikeda; Kazuhiko Mori; Morio Ueno; Kengo Yoshii; Yuko Maruyama; Kojiro Imai; Masakazu Nakano; Shigeru Kinoshita; Chie Sotozono

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3705.

ARVO Annual Meeting Abstract June 2017

Genome-wide association study of Fuchs endothelial corneal dystrophy in a Japanese population

Morio Ueno; Masakazu Nakano; Hiroko Nakagawa; Hiroko Adachi; Yuichi Tokuda; Yoko Ikeda; Chie Sotozono; Kei Tashiro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5657.

Letters to the Editor November 2016

Stronger Association of CDKN2B-AS1 Variants in Female Normal-Tension Glaucoma Patients in a Japanese Population

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Kazuhiko Mori; Masakazu Nakano; Yuichi Tokuda; Yoko Ikeda; Morio Ueno; Chie Sotozono; Shigeru Kinoshita; Kei Tashiro
TAGS: cdkn2b gene, japanese, low tension glaucoma
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6416-6417. https://doi.org/10.1167/iovs.16-20417

ARVO Annual Meeting Abstract September 2016

Trinucleotide repeat expansion and TCF4 gene expression in Fuchs endothelial corneal dystrophy

Keisuke Ogata; Naoki Okumura; Ryosuke Hayashi; Makiko Nakahara; Masakazu Nakano; Kei Tashiro; Shigeru Kinoshita; Ursula Schlötzer-Schrehardt; Theofilos Tourtas; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

Cornea July 2015

Trinucleotide Repeat Expansion in the TCF4 Gene in Fuchs' Endothelial Corneal Dystrophy in Japanese

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Masakazu Nakano; Naoki Okumura; Hiroko Nakagawa; Noriko Koizumi; Yoko Ikeda; Morio Ueno; Kengo Yoshii; Hiroko Adachi; Ross A. Aleff; Malinda L. Butz; W. Edward Highsmith; Kei Tashiro; Eric D. Wieben; Shigeru Kinoshita; Keith H. Baratz
TAGS: endothelium, genes, hereditary corneal dystrophy, trinucleotide repeat expansion
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4865-4869. https://doi.org/10.1167/iovs.15-17082

ARVO Annual Meeting Abstract June 2015

Detection of intraocular pressure seasonality in patients with various types of glaucoma

Kazuhiko Mori; Yoko Ikeda; Morio Ueno; Kengo Yoshii; Ryuichi Sato; Fumiko Sato; Masakazu Nakano; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2023.

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Dysregulation of the TCF4 Isoform in Corneal Endothelial Cells of Patients With Fuchs Endothelial Corneal Dystrophy

Investigation of the TCF4 Aberrant Splicing in the Corneal Endothelial Cells of Patients with Fuchs Endothelial Corneal Dystrophy

Investigation of the TCF4 Splicing and Isoform Expressions in the Corneal Endothelial Cells of Patients with Fuchs Endothelial Corneal Dystrophy

Identification of Sex-Biased Genes in the Human Corneal Endothelial Cells by using RNA Sequencing Analysis

RNA Sequencing Analysis of Corneal Endothelial Cells Derived from Fuchs Endothelial Corneal Dystrophy Patients with and without Trinucleotide Repeat Expansion in TCF4

Seasonal Variation of Intraocular Pressure in Non-Glaucomatous Subjects

RNA-Seq based transcriptome analysis of corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy

Trend of continuous intraocular pressure decrease over a 20-year period in Japanese normal tension glaucoma patients

Mitochondria as a Platform for Dictating the Cell Fate of Cultured Human Corneal Endothelial Cells

Polarized Expression of Ion Channels and Solute Carrier Family Transporters on Heterogeneous Cultured Human Corneal Endothelial Cells

Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany

Expression level of the TCF4 gene in the corneal endothelium of Fuchs endothelial corneal dystrophy patients

Glaucoma prevalence over time in Japanese from Kyoto Glaucoma Screening Cohort

Genome-wide association study of Fuchs endothelial corneal dystrophy in a Japanese population

Stronger Association of CDKN2B-AS1 Variants in Female Normal-Tension Glaucoma Patients in a Japanese Population

Trinucleotide repeat expansion and TCF4 gene expression in Fuchs endothelial corneal dystrophy

Trinucleotide Repeat Expansion in the TCF4 Gene in Fuchs' Endothelial Corneal Dystrophy in Japanese

Detection of intraocular pressure seasonality in patients with various types of glaucoma

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