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Journal Articles (4)

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Investigative Ophthalmology & Visual Science (4)

Article Type

Clinical Trials (2)
Clinical and Epidemiologic Research (1)
Letters to the Editor (1)

Topics

Eye Anatomy and Disorders (4)
Retina (3)
Clinical and Epidemiologic Research (1)
Imaging (1)
Immunology and Microbiology (1)
Low Vision (1)
Multidisciplinary Ophthalmic Imaging (1)

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placebos (3)
diabetic macular edema (2)
visual acuity (2)
administration, oral (1)
blindness (1)
diabetes mellitus (1)
diabetes mellitus, type 2 (1)
eye (1)
hemodynamics (1)
phase 3 clinical trials (1)

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Showing 1 – 4 of 4

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Clinical Trials March 2013

The Effect of the Oral PKC β Inhibitor Ruboxistaurin on Vision Loss in Two Phase 3 Studies

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Matthew J. Sheetz; Lloyd Paul Aiello; Matthew D. Davis; Ronald Danis; Toke Bek; Jose Cunha-Vaz; Nazila Shahri; Paul H. Berg; for the MBDL and MBCU Study Groups
TAGS: blindness, phase 3 clinical trials, placebos
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1750-1757. https://doi.org/10.1167/iovs.12-11055

Letters to the Editor December 2010

Author Response: Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema

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Matthew J. Sheetz; Matthew D. Davis; Lloyd P. Aiello; Roy C. Milton; Ronald P. Danis; Xin Zhi; Aniz Girach; Maria C. Jimenez; Louis Vignati; for the PKC-DRS2 Study Group
TAGS: diabetic macular edema, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6890-6891. https://doi.org/10.1167/iovs.09-4285

Clinical Trials January 2009

Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema

PDF

Matthew D. Davis; Matthew J. Sheetz; Lloyd P. Aiello; Roy C. Milton; Ronald P. Danis; Xin Zhi; Aniz Girach; Maria C. Jimenez; Louis Vignati
TAGS: diabetic macular edema, eye, placebos, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2009; 50(1):1-4. https://doi.org/10.1167/iovs.08-2473

Clinical and Epidemiologic Research January 2006

Inhibition of PKC β by Oral Administration of Ruboxistaurin Is Well Tolerated and Ameliorates Diabetes-Induced Retinal Hemodynamic Abnormalities in Patients

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Lloyd Paul Aiello; Allen Clermont; Vipin Arora; Matthew D. Davis; Matthew J. Sheetz; Sven-Eric Bursell
TAGS: administration, oral, diabetes mellitus, diabetes mellitus, type 2, hemodynamics, placebos, safety
Invest. Ophthalmol. Vis. Sci.. 2006; 47(1):86-92. https://doi.org/10.1167/iovs.05-0757

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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