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Anatomy and Pathology/Oncology September 2018

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

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Zachary K. Goldsmith; William Coppess; Andrew S. Irvine; Kelley Yuan; Samuel R. Barsh; Madison K. Ritter; Matthew W. McEwen; Jacqueline Flores-Otero; Aileen Garcia-Vargas; Magaly Martinez-Ferrer; Rachel C. Brennan; Vanessa M. Morales-Tirado; Matthew W. Wilson
TAGS: signal transduction, cell culture techniques, western blotting, enzyme-linked immunosorbent assay, blood platelets, cell proliferation, flow cytometry, cell lines, cell survival, platelet-derived growth factor, platelet-derived growth factor receptor, retinoblastoma, rna, messenger, seeds, spheroids, cellular, vitreous body, diagnostic imaging, eye, neoplasms, rna, small interfering, nuclear translocation, proto-oncogene proteins c-akt, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4486-4495. doi: 10.1167/iovs.18-24359

ARVO Annual Meeting Abstract July 2018

Protein Kinase C- delta Regulates Cellular Attachment, Survival, and Metastases-Associated Genes in Uveal Melanoma

Ansley K Ulmer; Bradley Gao; Zachary K. Goldsmith; Anna M Walsh; Sarah E Langsdon; Kelley Yuan; Matthew W Wilson; Vanessa Marie Morales-Tirado

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3168. doi:

ARVO Annual Meeting Abstract July 2018

Impaired p14 ARF and MDM2 Nuclecytoplasmic Shuttling in Uveal Melanoma

Vanessa Marie Morales-Tirado; Caroline Awh; Zachary K. Goldsmith; Monica M Jablonski; Benjamin King; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3174. doi:

ARVO Annual Meeting Abstract July 2018

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Matthew W Wilson; Matthew W McEwen; Zachary K. Goldsmith; Kelley Yuan; Andrew Irvine; Benjamin King; Hua Yang Yang; Hans Grossniklaus; Vanessa Marie Morales-Tirado

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3175. doi:

ARVO Annual Meeting Abstract July 2018

Chemoreduction with Topotecan and Vincristine: Clinical Validation of a Novel Chemotherapeutic Regimen for Bilateral Intraocular Retinoblastoma

Benjamin King; Matthew W Wilson; Rachel C Brennan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5982. doi:

ARVO Annual Meeting Abstract July 2018

Vitreous Seed and Soil: Elevated Levels of Platelet-Derived Growth Factor (PDGF) in the Vitreous of Patients with Retinoblastoma

Zachary K. Goldsmith; samuel R barsh; Kelley Yuan; Benjamin King; Rachel C Brennan; Matthew W Wilson; Vanessa Marie Morales-Tirado

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5984. doi:

ARVO Annual Meeting Abstract June 2017

Inhibition of PDGFR-β Decreases Pro-Survival Signaling of Retinoblastoma in vitro

Madison Ritter; William Coppess; Zachary K. Goldsmith; Rachel Brennan; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1779. doi:

ARVO Annual Meeting Abstract June 2017

The impact of disruption of PDGF-PDGFR-β signaling on VEGF-VEGFR signaling in retinoblastoma

William Coppess; Zachary K. Goldsmith; Madison Ritter; Kelley Yuan; Andrew S Irvine; Rachel Brennan; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1780. doi:

ARVO Annual Meeting Abstract June 2017

The effects of inhibition of PDGFR-β in retinal endothelial cells within the retinoblastoma tumor microenvironment

Zachary K. Goldsmith; William Coppess; Kelley Yuan; Andrew S Irvine; Rachel Brennan; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1781. doi:

ARVO Annual Meeting Abstract June 2017

Pre-clinical Model of Retinoblastoma Vitreous Seeds

Andrew S Irvine; Zachary K. Goldsmith; Rachel Brennan; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1770. doi:

ARVO Annual Meeting Abstract June 2017

The PDGF-PDGFR Signaling Pathway Regulates AKT Cell Survival and NF-kB anti-apoptotic effects in Retinoblastoma

Matthew W Wilson; Zachary K. Goldsmith; William Coppess; Kelley Yuan; Madison Ritter; Andrew Irvine; Rachel Brennan; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1778. doi:

ARVO Annual Meeting Abstract June 2017

Microenvironmental Regulation of the Liver Inflammasomes in Uveal Melanoma Favors Metastatic Growth

Vanessa Marie Morales; Zachary K. Goldsmith; Neel Patel; Benjamin A King; Hans E Grossniklaus; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3959. doi:

ARVO Annual Meeting Abstract June 2017

PKC-delta as a Survival Regulator in Uveal Melanoma

Bradley Gao; Mercy Kibe; Kelley Yuan; Hans E Grossniklaus; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3960. doi:

ARVO Annual Meeting Abstract September 2016

Decreasing cell survival in Retinoblastoma through PDGFR- β blockade

Zachary Goldsmith; Vanessa Marie Morales; Matthew McEwen; William Coppess; Andrew Irvine; Rachel C Brennan; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3659. doi:

ARVO Annual Meeting Abstract September 2016

Pharmacological Inhibition of Paxillin Reduces Cell Proliferation in Uveal Melanoma Cell Lines

Bradley Gao; Levon Djenderedjian; William Coppess; Zachary Goldsmith; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4118. doi:

ARVO Annual Meeting Abstract September 2016

Host Microenvironment Shapes Uveal Melanoma Tumor Properties

Matthew W McEwen; Qing Zhang; Bradley Gao; Hua Yang; Zachary Goldsmith; Hans E Grossniklaus; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Repeat Episcleral Plaque Brachytherapy: Clinical Outcomes in Patients Treated for Locally Recurrent Choroidal Melanoma (CM)

Benjamin King; Henry Wynn; Bradley Gao; Vanessa Marie Morales; Matthew T Ballo; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4094. doi:

ARVO Annual Meeting Abstract September 2016

Paxillin regulates UM cell survival by PKC-delta signaling

Vanessa Marie Morales; Sumana R Chintalapudi; Zachary Goldsmith; Bradley Gao; Pia Mendoza; Hans E Grossniklaus; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4120. doi:

ARVO Annual Meeting Abstract September 2016

Invasive corneal squamous cell carcinoma: A case series of five

Caroline M Craven; Pia R Mendoza; Matthew Hochuen Ip; Matthew W Wilson; Minas T Coroneo; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2412. doi:

ARVO Annual Meeting Abstract September 2016

PDGF-PDGFR Signaling Sustain Angiogenesis in an Autocrine and Paracrine Fashion in Retinoblastoma

Matthew W Wilson; Zachary Goldsmith; William Coppess; Bradley Gao; Matthew McEwen; Andrew Irvine; Rachel C Brennan; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

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Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

Protein Kinase C- delta Regulates Cellular Attachment, Survival, and Metastases-Associated Genes in Uveal Melanoma

Impaired p14 ARF and MDM2 Nuclecytoplasmic Shuttling in Uveal Melanoma

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Chemoreduction with Topotecan and Vincristine: Clinical Validation of a Novel Chemotherapeutic Regimen for Bilateral Intraocular Retinoblastoma

Vitreous Seed and Soil: Elevated Levels of Platelet-Derived Growth Factor (PDGF) in the Vitreous of Patients with Retinoblastoma

Inhibition of PDGFR-β Decreases Pro-Survival Signaling of Retinoblastoma in vitro

The impact of disruption of PDGF-PDGFR-β signaling on VEGF-VEGFR signaling in retinoblastoma

The effects of inhibition of PDGFR-β in retinal endothelial cells within the retinoblastoma tumor microenvironment

Pre-clinical Model of Retinoblastoma Vitreous Seeds

The PDGF-PDGFR Signaling Pathway Regulates AKT Cell Survival and NF-kB anti-apoptotic effects in Retinoblastoma

Microenvironmental Regulation of the Liver Inflammasomes in Uveal Melanoma Favors Metastatic Growth

PKC-delta as a Survival Regulator in Uveal Melanoma

Decreasing cell survival in Retinoblastoma through PDGFR- β blockade

Pharmacological Inhibition of Paxillin Reduces Cell Proliferation in Uveal Melanoma Cell Lines

Host Microenvironment Shapes Uveal Melanoma Tumor Properties

Repeat Episcleral Plaque Brachytherapy: Clinical Outcomes in Patients Treated for Locally Recurrent Choroidal Melanoma (CM)

Paxillin regulates UM cell survival by PKC-delta signaling

Invasive corneal squamous cell carcinoma: A case series of five

PDGF-PDGFR Signaling Sustain Angiogenesis in an Autocrine and Paracrine Fashion in Retinoblastoma

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