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ARVO Annual Meeting Abstract June 2022

The generation and characterization of a large animal model of USH3 disease

Astra Dinculescu; Maureen A McCall; Ronald G Gregg; Archana Jalligampala; Jennifer M. Noel; Rebecca Whiting; Kevin Donnelly; Kristin Whitworth; Randall S Prather; Kevin D Wells; Bethany Redel; J. Hugh McDowell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1926 – A0072. doi:

ARVO Annual Meeting Abstract June 2022

Characterization of a Humanized Mouse Model of P23H Rhodopsin Autosomal Dominant Retinitis Pigmentosa (adRP)

Maureen A McCall; Olivia N Jacobs; Nazarul Hasan; Jeff Smith; Derek Jantz; Victor Bartsevich; Dale Cowley; Kristi Viles

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2607 – F0490. doi:

ARVO Annual Meeting Abstract June 2022

Stereopure oligonucleotide treatment results in durable rescue of disease phenotype in a P23H hRHO pig model of human autosomal dominant retinitis pigmentosa (adRP)

Jennifer M. Noel; Archana Jalligampala; Olivia N Jacobs; Joseph Prestigiacomo; Hailin Yang; Qianli Pan; Fangjun Liu; Yuan Yin; Richard Looby; Chandra Vargeese; Michael Byrne; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4289. doi:

ARVO Annual Meeting Abstract June 2022

Multiple glycinergic subunits mediate inhibitory inputs to mouse ON-OFF Direction Selective Ganglion Cells

Chase B Hellmer; Ian Pyle; Caitlin White; Chi Zhang; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4571 – F0433. doi:

ARVO Annual Meeting Abstract June 2022

Successful late-stage disease treatment of P23H human RHO (hRHO) using ARCUS nuclease gene editing in a pig model of Autosomal Dominant Retinitis Pigmentosa (adRP)

Archana Jalligampala; Jennifer M. Noel; Olivia Noelle Jacobs; Alec Lynn Bradley; Wei Wang; Maha Haleem Jabbar; Nazarul Hasan; Joseph Prestigiacomo; Jeff Smith; Victor Bartsevich; Kristi Viles; Derek Jantz; Maureen Ann McCall

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1107. doi:

ARVO Annual Meeting Abstract June 2021

Allele-selective reduction of P23H-mutant rhodopsin with stereopure oligonucleotides rescues phenotype associated with retinitis pigmentosa in preclinical models

Michael Byrne; Vinod Vathipadickal; Lankai Guo; Yuan Yin; Hailin Yang; Richard Looby; Lauren Norwood; James W Fransen; archana jalligampala; Jennifer Noel; Chandra Vargeese; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):185. doi:

ARVO Annual Meeting Abstract June 2021

Rho 1-2 meganuclease, an allele-specific gene-editing therapy, rejuvenates rod photoreceptor structure and function in a pig model of autosomal dominant Retinitis Pigmentosa (adRP).

archana jalligampala; Jennifer Noel; James W Fransen; Wei Wang; Maha Jabbar; Nazarul Hasan; Gobinda Pangeni; Bhubanananda Sahu; Whitney Lewis; Jeff Smith; Victor Bartsevich; Kristi Viles; Derek Jantz; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1478. doi:

ARVO Annual Meeting Abstract June 2021

SPVN06, a Novel Mutation-Independent AAV-based Gene Therapy, Protects Cone Degeneration in a Pig Model of Retinitis Pigmentosa

Jennifer Noel; archana jalligampala; Myriam Marussig; Pierre-Axel VINOT; Melanie MARIE; Melanie Butler; Florence LORGET; Stephane Boissel; Thierry D Leveillard; Jose Alain Sahel; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1189. doi:

ARVO Annual Meeting Abstract June 2020

Stereopure oligonucleotides achieve allele-selective reduction of P23H mutant rhodopsin

Vinod Vathipadiekal; Lankai Guo; Yuan Yin; Qiong Shen; Hailin Yang; Richard Looby; Lauren Norwood; James Fransen; archana jalligampala; Jennifer Noel; Chandra Vargeese; Maureen A McCall; Michael Byrne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1912. doi:

ARVO Annual Meeting Abstract June 2020

Allele-specific Homing Endonuclease (HE) Gene Editing Induces Rod Function in a P23H Transgenic Swine Model of Retinitis Pigmentosa

James W Fransen; archana jalligampala; Jennifer Noel; Wei Wang; Jeff Smith; Victor Bartsevich; Kristi Viles; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1915. doi:

ARVO Annual Meeting Abstract June 2020

An Allele-Independent Gene Therapy Strategy Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

archana jalligampala; James Fransen; Jennifer Noel; Gobinda Pangeni; Maha Haleem Jabbar; William W Hauswirth; Alfred S Lewin; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4484. doi:

Retina June 2020

Electroretinogram of the Cone-Dominant Thirteen-Lined Ground Squirrel during Euthermia and Hibernation in Comparison with the Rod-Dominant Brown Norway Rat

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Hanmeng Zhang; Benjamin S. Sajdak; Dana K. Merriman; Maureen A. McCall; Joseph Carroll; Daniel M. Lipinski
TAGS: electroretinography, hibernating myocardium, rats, inbred bn, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):6. doi: https://doi.org/10.1167/iovs.61.6.6

Includes: Supplemental Content

Articles December 2019

Noninvasive Imaging and Correlative Histology of Cone Photoreceptor Structure in the Pig Retina

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Alison L. Huckenpahler; Joseph Carroll; Alexander E. Salmon; Benjamin S. Sajdak; Rebecca R. Mastey; Kenneth P. Allen; Henry J. Kaplan; Maureen A. McCall
TAGS: diagnostic imaging, histology, retina, retinal cone, suidae
Trans. Vis. Sci. Tech.. 2019; 8(6):38. doi: https://doi.org/10.1167/tvst.8.6.38

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Allele-specific Gene Editing Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

Maureen A McCall; Archana Jalligampala; gobinda Pangeni; Maha Jabbar; Henry J Kaplan; Wei Wang; Bhubanananda Sahu; Jon E Chatterton; Jeff Smith; Victor Bartsevich; Kristi Viles

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4229. doi:

ARVO Annual Meeting Abstract July 2019

Role of presynaptic LRIT3 expression in the restoration of dim light vision

Nazarul Hasan; gobinda Pangeni; Catherine Cobb; Emily R. Nettesheim; Daniel M. Lipinski; Maureen A McCall; Ronald G Gregg

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4788. doi:

ARVO Annual Meeting Abstract July 2019

A comparison of the electroretinogram in the cone-dominant thirteen-lined ground squirrel and the rod-dominant Brown Norway rat

Hanmeng Zhang; Benjamin S Sajdak; Dana K. Merriman; Joseph Carroll; Maureen A McCall; Daniel M. Lipinski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5971. doi:

ARVO Annual Meeting Abstract July 2018

Histologic correlation of cone photoreceptor maturation with ultrahigh resolution OCT in wild type swine

Niloofar Piri; Patrick A Scott; Henry J Kaplan; Bhubanananda Sahu; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):729. doi:

ARVO Annual Meeting Abstract June 2017

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Saumil Sethna; Patrick A Scott; Arnaud Giese; Mary A Johnson; Saima Riazuddin; Steven L Bernstein; Maureen A McCall; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):270. doi:

ARVO Annual Meeting Abstract June 2017

A dual function for LRIT3 – control of retinal photoreceptor synaptic morphology and depolarizing bipolar cell signaling

Nazarul Hasan; Jennifer Noel; Ian Scot Pyle; Gobinda Pangeni; Kathryn M Heath; Bart Gerard Borghuis; Maureen A McCall; Ronald G Gregg

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1031. doi:

ARVO Annual Meeting Abstract June 2017

Oscillating eye movements in nob mice are explained by oscillating ON-direction selective ganglion cells

Maarten Kamermans; Kathryn Fransen; Gobinda Pangeni; Marcus Howlett; Maj-Britt Holzel; Maureen A McCall; Chris Zeeuw de; Beerend Winkelman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2232. doi:

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The generation and characterization of a large animal model of USH3 disease

Characterization of a Humanized Mouse Model of P23H Rhodopsin Autosomal Dominant Retinitis Pigmentosa (adRP)

Stereopure oligonucleotide treatment results in durable rescue of disease phenotype in a P23H hRHO pig model of human autosomal dominant retinitis pigmentosa (adRP)

Multiple glycinergic subunits mediate inhibitory inputs to mouse ON-OFF Direction Selective Ganglion Cells

Successful late-stage disease treatment of P23H human RHO (hRHO) using ARCUS nuclease gene editing in a pig model of Autosomal Dominant Retinitis Pigmentosa (adRP)

Allele-selective reduction of P23H-mutant rhodopsin with stereopure oligonucleotides rescues phenotype associated with retinitis pigmentosa in preclinical models

Rho 1-2 meganuclease, an allele-specific gene-editing therapy, rejuvenates rod photoreceptor structure and function in a pig model of autosomal dominant Retinitis Pigmentosa (adRP).

SPVN06, a Novel Mutation-Independent AAV-based Gene Therapy, Protects Cone Degeneration in a Pig Model of Retinitis Pigmentosa

Stereopure oligonucleotides achieve allele-selective reduction of P23H mutant rhodopsin

Allele-specific Homing Endonuclease (HE) Gene Editing Induces Rod Function in a P23H Transgenic Swine Model of Retinitis Pigmentosa

An Allele-Independent Gene Therapy Strategy Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

Electroretinogram of the Cone-Dominant Thirteen-Lined Ground Squirrel during Euthermia and Hibernation in Comparison with the Rod-Dominant Brown Norway Rat

Noninvasive Imaging and Correlative Histology of Cone Photoreceptor Structure in the Pig Retina

Allele-specific Gene Editing Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

Role of presynaptic LRIT3 expression in the restoration of dim light vision

A comparison of the electroretinogram in the cone-dominant thirteen-lined ground squirrel and the rod-dominant Brown Norway rat

Histologic correlation of cone photoreceptor maturation with ultrahigh resolution OCT in wild type swine

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

A dual function for LRIT3 – control of retinal photoreceptor synaptic morphology and depolarizing bipolar cell signaling

Oscillating eye movements in nob mice are explained by oscillating ON-direction selective ganglion cells

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