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ARVO Annual Meeting Abstract July 2018

Wedelolactone protects DNA-induced photoreceptor death

Kevin Harkin; Sofia Pavlou; Alan W Stitt; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1002. doi:

ARVO Annual Meeting Abstract July 2018

Increased diabetic retinal neuronal degeneration in IL-33 -/- mice is related to reduced Müller cell-derived neurotrophic factors

Josy Augustine; Sofia Pavlou; Alan W Stitt; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1211. doi:

ARVO Annual Meeting Abstract July 2018

Topical treatment for AMD: Non-invasive delivery and efficacy of ranibizumab and bevacizumab in rabbit and porcine eyes

Felicity De Cogan; Aisling Lynch; Matthew Berwick; Anna Peacock; Samer Elsherbiny; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1439. doi:

ARVO Annual Meeting Abstract July 2018

NRF-2/PGC-1α deficiency induces retinal degeneration in mice

Niko Kivinen; Szabolcs Felszeghy; Jussi Paterno; Johanna Viiri; Mei Chen; Debasish Sinha; Deborah A. Ferrington; Ram Kannan; Anu Kauppinen; Kai Kaarniranta

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2455. doi:

ARVO Annual Meeting Abstract July 2018

Interleukin-33 deficiency resulted in severe neuroretinal degeneration in retinal detachment

Mei Chen; Josy Augustine; Sofia Pavlou; Imran Ali; Sarah Doyle; Alan W Stitt; Matthew Campbell; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3942. doi:

ARVO Annual Meeting Abstract July 2018

Complement C3a Induces Macrophage to Myofibroblast Transition (MMT) in Sub-retinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration

Karis Little; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5552. doi:

ARVO Annual Meeting Abstract July 2018

Photoreceptors Constitutively Express A Variety of Complement Components

Jian Liu; Kevin Harkin; Chang Luo; Jiansu Chen; Shibo Tang; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5556. doi:

ARVO Annual Meeting Abstract July 2018

Long-term Low-dose Aspirin Exacerbates Laser-induced Choroidal Neovascularization Through Down-regulating Thrombospondin-1 Expression

Chang Luo; Mei Chen; Rosana G. Penalva; Jiawu Zhao; Jiansu Chen; Shibo Tang; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5557. doi:

Retinal Cell Biology March 2018

Characterization of a Spontaneously Immortalized Murine Müller Glial Cell Line QMMuC-1

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Josy Augustine; Sofia Pavlou; Michael O'Hare; Kevin Harkin; Alan Stitt; Tim Curtis; Heping Xu; Mei Chen
TAGS: cytokine, glial fibrillary acidic protein, neuroglia, mice, glutamate
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1666-1674. doi: 10.1167/iovs.17-23293

ARVO Annual Meeting Abstract June 2017

Plasma level of lipocalin-2 is increased in neovascular age-related macular degeneration, particularly in patients with macular fibrosis

Nan Yang; Judith Lechner; Ruth E Hogg; Levente Toth; Giuliana Silvestri; Usha Chakravarthy; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1626. doi:

ARVO Annual Meeting Abstract June 2017

Alterations in Circulating Leukocyte Populations in Diabetic Retinopathy

Gideon Obasanmi; Nuala-Jane Lavery; Jose Romero Hombrebueno; Aisling Lynch; Mei Chen; David Armstrong; Noemi Lois; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2506. doi:

ARVO Annual Meeting Abstract June 2017

VEGF-Mediated Activation of Intracellular Signaling in Human Retinal Endothelial Cells is a Very Sharp and Switch-like Dose Response

Kenneth P Mitton; Wendelin Dailey; Austen N Knapp; Peter F Chen; Regan Miller; Mei Cheng; Brandon Metcalf; Quentin Tompkins; Ed Guzman; Jennifer Felisky; Mrinalini Deshpande

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1898. doi:

Nantotechnology and Regenerative Medicine May 2017

Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides

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Felicity de Cogan; Lisa J. Hill; Aisling Lynch; Peter J. Morgan-Warren; Judith Lechner; Matthew R. Berwick; Anna F. A. Peacock; Mei Chen; Robert A. H. Scott; Heping Xu; Ann Logan
TAGS: choroidal neovascularization, peptides, cornea, eye, mice, retina, bevacizumab, eyedrops, cpps trial, complex, anti-vascular endothelial growth factor therapy
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2578-2590. doi: 10.1167/iovs.16-20072

ARVO Annual Meeting Abstract September 2016

Pharmacological inhibition of STAT3 suppresses pathologic retinal neo-vascular growth in the mouse model of oxygen-induced retinopathy

Jose R Hombrebueno; Aisling Lynch; Gideon Obasanmi; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3227. doi:

ARVO Annual Meeting Abstract September 2016

Cell-penetrating peptides as non-invasive drug delivery vehicles for ranibizumab and bevacizumab.

Felicity de Cogan; Lisa J Hill; Peter Morgan-Warren; Mei Chen; Robert Scott; Heping Xu; Ann Logan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4037. doi:

ARVO Annual Meeting Abstract September 2016

Photoreceptor outer segments (POS) induce Retinal pigment epithelial (RPE) cell multinucleation through modulating the Protein Kinase C pathway

Dinusha Rajapakse; Mei Chen; Tim Curtis; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Long-term safety evaluation of suprachoroidal space following multiple suprachoroidal injection of triamcinolone acetonide (TA)

Mei Chen; Shiyu Zhou; Ping Lu; Qingkai Ma; Akram Belghith; Lingyun Cheng

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):762. doi:

ARVO Annual Meeting Abstract September 2016

Control microglial activation by targeting the glucose transporter 1

LUXI WANG; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Attenuating diabetic vascular degeneration by targeting the P2X7 receptor

Mei Chen; Sofia Pavlou; Ronan Cunning; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2713. doi:

ARVO Annual Meeting Abstract September 2016

Inflammasome activation in the photoreceptor cells

Ronan Cunning; Sofia Pavlou; Alan W Stitt; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2730. doi:

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Wedelolactone protects DNA-induced photoreceptor death

Increased diabetic retinal neuronal degeneration in IL-33 -/- mice is related to reduced Müller cell-derived neurotrophic factors

Topical treatment for AMD: Non-invasive delivery and efficacy of ranibizumab and bevacizumab in rabbit and porcine eyes

NRF-2/PGC-1α deficiency induces retinal degeneration in mice

Interleukin-33 deficiency resulted in severe neuroretinal degeneration in retinal detachment

Complement C3a Induces Macrophage to Myofibroblast Transition (MMT) in Sub-retinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration

Photoreceptors Constitutively Express A Variety of Complement Components

Long-term Low-dose Aspirin Exacerbates Laser-induced Choroidal Neovascularization Through Down-regulating Thrombospondin-1 Expression

Characterization of a Spontaneously Immortalized Murine Müller Glial Cell Line QMMuC-1

Plasma level of lipocalin-2 is increased in neovascular age-related macular degeneration, particularly in patients with macular fibrosis

Alterations in Circulating Leukocyte Populations in Diabetic Retinopathy

VEGF-Mediated Activation of Intracellular Signaling in Human Retinal Endothelial Cells is a Very Sharp and Switch-like Dose Response

Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides

Pharmacological inhibition of STAT3 suppresses pathologic retinal neo-vascular growth in the mouse model of oxygen-induced retinopathy

Cell-penetrating peptides as non-invasive drug delivery vehicles for ranibizumab and bevacizumab.

Photoreceptor outer segments (POS) induce Retinal pigment epithelial (RPE) cell multinucleation through modulating the Protein Kinase C pathway

Long-term safety evaluation of suprachoroidal space following multiple suprachoroidal injection of triamcinolone acetonide (TA)

Control microglial activation by targeting the glucose transporter 1

Attenuating diabetic vascular degeneration by targeting the P2X7 receptor

Inflammasome activation in the photoreceptor cells

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