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Biochemistry and Molecular Biology September 2020

VEGF-B Is an Autocrine Gliotrophic Factor for Müller Cells under Pathologic Conditions

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María Llorián-Salvador; Peter Barabas; Eimear M. Byrne; Judith Lechner; Josy Augustine; Timothy M. Curtis; Mei Chen; Heping Xu
TAGS: vascular endothelial growth factor b, vascular endothelial growth factor a, hypoxia
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):35. doi: https://doi.org/10.1167/iovs.61.11.35

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Interleukin-17A mediates Blood-Retinal Barrier breakdown in vitro and in vivo via the JAK/STAT pathway

Eimear Margaret Byrne; Maria Llorian-Salvador; Andriana Margariti; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):41. doi:

ARVO Annual Meeting Abstract June 2020

Complement C5a induced Epithelium to Mesenchymal Transition (EMT) in retinal pigment epithelial cells

Maria Llorian-Salvador; Eimear Margaret Byrne; Karis Little; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1116. doi:

ARVO Annual Meeting Abstract June 2020

Identification of age-related changes in retinal immune regulatory genes using Single-Cell transcriptomics

Miao Tang; Bin Zou; Lai Wei; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5406. doi:

ARVO Annual Meeting Abstract June 2020

SBC003 demonstrates neuroprotective effects in a murine model of N-nitroso-N-methylurea (NMU) induced photoreceptor degeneration

Yuhong Dong; Kevin Harkin; Laurence Feraille; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2475. doi:

Articles March 2020

A Two-Stage Laser-Induced Mouse Model of Subretinal Fibrosis Secondary to Choroidal Neovascularization

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Karis Little; María Llorián-Salvador; Miao Tang; Xuan Du; Órlaith O'Shaughnessy; Gemma McIlwaine; Mei Chen; Heping Xu
TAGS: choroidal neovascularization, fibrosis, lasers, mice
Trans. Vis. Sci. Tech.. 2020; 9(4):3. doi: https://doi.org/10.1167/tvst.9.4.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

The inflammasome pathway is activated in the retina of type 2 but not type 1 diabetic mice

Kevin Harkin; Mei Chen; Heping Xu; Sofia Pavlou

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):768. doi:

ARVO Annual Meeting Abstract July 2019

A two-stage laser induced model of sub-retinal fibrosis

Karis Little; Maria Llorian-Salvador; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1263. doi:

ARVO Annual Meeting Abstract July 2019

VEGF-B protects Müller cells from hypoxic- and oxidative stress-mediated damage

Maria Llorian-Salvador; Judith Lechner; Peter Barabas; Eimear Byrne; Josy Augustine; Tim M Curtis; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1675. doi:

ARVO Annual Meeting Abstract July 2019

SIGIRR deficiency accelerates diabetes-induced retinal neurodegeneration

Mei Chen; Sofia Pavlou; Josy Augustine; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2656. doi:

ARVO Annual Meeting Abstract July 2019

Age-dependent development of retinal microgliopathy in LysM Cre/+ SOCS3 fl/fl CX3CR1 gfp/gfp mice

Xuan Du; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2796. doi:

ARVO Annual Meeting Abstract July 2019

Adaptive Optics OCT-Based Drusen Grading for Assessing Severity of Dry Age-Related Macular Degeneration

Stacey S Choi; Elaine Wells-Gray; Heping Xu; Brian Vohnsen; Mei Chen; Loraine T Sinnott; Lisa Jordan; Matthew Ohr; Colleen M Cebulla; Nathan Doble

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3465. doi:

ARVO Annual Meeting Abstract July 2019

Effect of cold provocation on vessel density in eyes with primary open angle glaucoma: an optical coherence tomography angiography study

Yu-Chieh Ko; Wei-Yi Chou; Mei-Ju Chen; Catherine Jui-Ling Liu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5622. doi:

ARVO Annual Meeting Abstract July 2018

Wedelolactone protects DNA-induced photoreceptor death

Kevin Harkin; Sofia Pavlou; Alan W Stitt; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1002. doi:

ARVO Annual Meeting Abstract July 2018

Increased diabetic retinal neuronal degeneration in IL-33 -/- mice is related to reduced Müller cell-derived neurotrophic factors

Josy Augustine; Sofia Pavlou; Alan W Stitt; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1211. doi:

ARVO Annual Meeting Abstract July 2018

Topical treatment for AMD: Non-invasive delivery and efficacy of ranibizumab and bevacizumab in rabbit and porcine eyes

Felicity De Cogan; Aisling Lynch; Matthew Berwick; Anna Peacock; Samer Elsherbiny; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1439. doi:

ARVO Annual Meeting Abstract July 2018

NRF-2/PGC-1α deficiency induces retinal degeneration in mice

Niko Kivinen; Szabolcs Felszeghy; Jussi Paterno; Johanna Viiri; Mei Chen; Debasish Sinha; Deborah A. Ferrington; Ram Kannan; Anu Kauppinen; Kai Kaarniranta

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2455. doi:

ARVO Annual Meeting Abstract July 2018

Interleukin-33 deficiency resulted in severe neuroretinal degeneration in retinal detachment

Mei Chen; Josy Augustine; Sofia Pavlou; Imran Ali; Sarah Doyle; Alan W Stitt; Matthew Campbell; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3942. doi:

ARVO Annual Meeting Abstract July 2018

Complement C3a Induces Macrophage to Myofibroblast Transition (MMT) in Sub-retinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration

Karis Little; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5552. doi:

ARVO Annual Meeting Abstract July 2018

Photoreceptors Constitutively Express A Variety of Complement Components

Jian Liu; Kevin Harkin; Chang Luo; Jiansu Chen; Shibo Tang; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5556. doi:

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VEGF-B Is an Autocrine Gliotrophic Factor for Müller Cells under Pathologic Conditions

Interleukin-17A mediates Blood-Retinal Barrier breakdown in vitro and in vivo via the JAK/STAT pathway

Complement C5a induced Epithelium to Mesenchymal Transition (EMT) in retinal pigment epithelial cells

Identification of age-related changes in retinal immune regulatory genes using Single-Cell transcriptomics

SBC003 demonstrates neuroprotective effects in a murine model of N-nitroso-N-methylurea (NMU) induced photoreceptor degeneration

A Two-Stage Laser-Induced Mouse Model of Subretinal Fibrosis Secondary to Choroidal Neovascularization

The inflammasome pathway is activated in the retina of type 2 but not type 1 diabetic mice

A two-stage laser induced model of sub-retinal fibrosis

VEGF-B protects Müller cells from hypoxic- and oxidative stress-mediated damage

SIGIRR deficiency accelerates diabetes-induced retinal neurodegeneration

Age-dependent development of retinal microgliopathy in LysM Cre/+ SOCS3 fl/fl CX3CR1 gfp/gfp mice

Adaptive Optics OCT-Based Drusen Grading for Assessing Severity of Dry Age-Related Macular Degeneration

Effect of cold provocation on vessel density in eyes with primary open angle glaucoma: an optical coherence tomography angiography study

Wedelolactone protects DNA-induced photoreceptor death

Increased diabetic retinal neuronal degeneration in IL-33 -/- mice is related to reduced Müller cell-derived neurotrophic factors

Topical treatment for AMD: Non-invasive delivery and efficacy of ranibizumab and bevacizumab in rabbit and porcine eyes

NRF-2/PGC-1α deficiency induces retinal degeneration in mice

Interleukin-33 deficiency resulted in severe neuroretinal degeneration in retinal detachment

Complement C3a Induces Macrophage to Myofibroblast Transition (MMT) in Sub-retinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration

Photoreceptors Constitutively Express A Variety of Complement Components

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