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ARVO Annual Meeting Abstract June 2024

ARMS2 A69S is associated with an increased level of retinal degeneration in a co-culture model for AMD

Merve Sen; Emanuel ten Brink; Kevin Elsner; Ellen Kilger; Angela Armento; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):770.

ARVO Annual Meeting Abstract June 2024

Complement Factor H (CFH) Y402H polymorphism alters the endoplasmic reticulum (ER) stress response in iPSC-RPE cells

Angela Armento; Inga Sonntag; Merve Sen; Simon John Clark; Rosario Fernandez-godino; Berta de la Cerda; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):727.

ARVO Annual Meeting Abstract June 2024

Valosin-Containing Protein Inhibition: Neuroprotective Strategy Against Retinal Degeneration in Porcine and Human Models.

Ana Cristina Almansa Garcia; Bowen Cao; Angela Armento; Merve Sen; Ellen Kilger; Anne-Sophie Petremann Dumé; Sylvia Bolz; Christine Henes; Blanca Arango-Gonzalez; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1240.

ARVO Annual Meeting Abstract June 2024

Pharmacological inhibition or genetic inactivation of ERAD effector VCP suppresses Rho ΔI255 -associated retinal degeneration

Bowen Cao; Johanna Valentina Dahlen; Ana Cristina Almansa Garcia; Merve Sen; Tina Beyer; Ellen Kilger; Francois Paquet-Durand; Blanca Arango-Gonzalez; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2198.

ARVO Annual Meeting Abstract June 2024

Inhibition of valosin-containing protein (VCP) prevents retinal degeneration in P23H transgenic rats, a model for autosomal dominant RP.

Blanca Arango-Gonzalez; Bowen Cao; Ana Cristina Almansa Garcia; Ellen Kilger; Angela Armento; Rosellina Guarascio; Kalliopi Ziaka; Kwan-Leong Hau; Hannah Poultney; Rowan Asfahani; Anne-Sophie Petremann Dumé; Sylvia Bolz; Michael E Cheetham; Merve Sen; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4735.

ARVO Annual Meeting Abstract June 2023

Complement Factor H (CFH) Y402H polymorphism alters the stress response of iPSC-RPE cells and leads to retinal degeneration in a novel co-culture model for Age-related Macular Degeneration (AMD)

Angela Armento; Inga Sonntag; Merve Sen; Simon J Clark; rosario fernandez-godino; Berta de la Cerda; marius ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5074.

ARVO Annual Meeting Abstract June 2023

The autosomal dominant R ho lle256del mutation causes protein aggregation and is processed by the VCP-dependent ERAD pathway

Bowen Cao; Johanna Valentina Dahlen; Merve Sen; Tobias Leonhard; Tina Beyer; Blanca Arango Gonzalez; marius ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1553.

ARVO Annual Meeting Abstract June 2023

Pharmacological targeting of VCP in porcine and human organotypic retinal explants.

Ana Cristina Almansa Garcia; Bowen Cao; Merve Sen; Angela Armento; Sylvia Bolz; Blanca Arango Gonzalez; marius ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1517.

ARVO Annual Meeting Abstract June 2023

Impact of the ARMS2 AMD-associated A69S polymorphism on the extracellular matrix of retinal pigment epithelium cells

Merve Sen; Angela Armento; Kevin Elsner; Ellen Kilger; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2109.

ARVO Annual Meeting Abstract July 2019

Inhibition of VCP structurally and functionally reconstitutes photoreceptor cells in Rh P23H organotypic retina cultures

Blanca Arango-Gonzalez; Merve Sen; Tsui-Fen Chou; Ray Deshaies; Sylvia Bolz; Wadood Haq; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4878.

ARVO Annual Meeting Abstract July 2019

Pharmacological interference in the VCP/ERAD/proteasome axis rescues photoreceptor degeneration in Rh P23H

Merve Sen; Oksana Kutsyr; Sylvia Bolz; Tsui-Fen Chou; Ray Deshaies; Blanca Arango-Gonzalez; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4881.

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