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Articles July 2021

Electrophysiologic and Morphologic Strain Differences in a Low-Dose NaIO 3 -Induced Retinal Pigment Epithelium Damage Model

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Nan Zhang; Xian Zhang; Preston E. Girardot; Micah A. Chrenek; Jana T. Sellers; Ying Li; Yong-Kyu Kim; Vivian R. Summers; Salma Ferdous; Debresha A. Shelton; Jeffrey H. Boatright; John M. Nickerson
TAGS: diagnostic imaging, electroretinography, injections, mice, mice, inbred c57bl, retinal pigment epithelium, painful bladder syndrome, retinal pigment cell, fluorescent antibody technique
Trans. Vis. Sci. Tech.. 2021; 10(8):10. doi: https://doi.org/10.1167/tvst.10.8.10

ARVO Annual Meeting Abstract June 2021

The effects of light-induced retinal damage (LIRD) in C57BL6/J mouse is mediated by RPE-65 activity

Debresha Shelton; Salma Ferdous; Vivian Summers; Isabelle Gefke; Micah A Chrenek; Preston Girardot; Jeffrey H Boatright; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2993. doi:

ARVO Annual Meeting Abstract June 2021

DMSO Protects Retinal Function in Two Mouse Models

Jana T Sellers; Micah A Chrenek; Preston Girardot; Stephanie L Foster; Priscila P Cunha; John M Nickerson; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2957. doi:

ARVO Annual Meeting Abstract June 2021

Electrophysiological and morphological changes in a low dose sodium iodate induced RPE damage model

Nan Zhang; Xian Zhang; Preston Girardot; Vivian Summers; Micah A Chrenek; Jana T Sellers; Ying Li; Salma Ferdous; Yong-Kyu Kim; Debresha Shelton; John M Nickerson; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2954. doi:

ARVO Annual Meeting Abstract June 2021

Oral supplementary nicotinamide riboside protects function in a model of inherited mouse glaucoma

Ying Li; Nan Zhang; Xian Zhang; Micah A Chrenek; Jiaxing Wang; Jana T Sellers; Brenner Charles; Eldon Geisert; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2767. doi:

ARVO Annual Meeting Abstract June 2021

Long-term Systemic Pentosan Polysulfate Administration Causes Retinal Function Decrease with Changes in Cell Markers

Preston Girardot; Xian Zhang; Micah A Chrenek; Jana T Sellers; Nan Zhang; Nieraj Jain; John M Nickerson; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3131. doi:

Retinal Cell Biology February 2021

Morphometric Analysis of Retinal Pigment Epithelial Cells From C57BL/6J Mice During Aging

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Yong-Kyu Kim; Hanyi Yu; Vivian R. Summers; Kevin J. Donaldson; Salma Ferdous; Debresha Shelton; Nan Zhang; Micah A. Chrenek; Yi Jiang; Hans E. Grossniklaus; Jeffrey H. Boatright; Jun Kong; John M. Nickerson
TAGS: aging, mice, mice, inbred c57bl, retinal pigment cell, optic disk, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):32. doi: https://doi.org/10.1167/iovs.62.2.32

Includes: Supplemental Content

Biochemistry and Molecular Biology August 2020

Systemic Treatment With Nicotinamide Riboside Is Protective in a Mouse Model of Light-Induced Retinal Degeneration

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Xian Zhang; Nathaniel F. Henneman; Preston E. Girardot; Jana T. Sellers; Micah A. Chrenek; Ying Li; Jiaxing Wang; Charles Brenner; John M. Nickerson; Jeffrey H. Boatright
TAGS: mice, niacinamide, retinal degeneration, systemic therapy, painful bladder syndrome
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):47. doi: https://doi.org/10.1167/iovs.61.10.47

Includes: Supplemental Content

Visual Neuroscience June 2020

Effects of Cone Connexin-36 Disruption on Light Adaptation and Circadian Regulation of the Photopic ERG

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Shuo Zhang; Polina Lyuboslavsky; Jendayi Azeezah Dixon; Micah A. Chrenek; Jana T. Sellers; Jessica M. Hamm; Christophe P. Ribelayga; Zhijing Zhang; Yun Z. Le; P. Michael Iuvone
TAGS: electroretinography, gap junction protein, light adaptation, mice, retinal cone, regulation
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):24. doi: https://doi.org/10.1167/iovs.61.6.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Visual defects in mice lacking circadian rhythm function in cone photoreceptors

Jess HAMM; Polina L Lyuboslavski; Shuo Zhang; Micah A Chrenek; P. Michael Iuvone

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2713. doi:

ARVO Annual Meeting Abstract June 2020

Optimization of a Retinal Pigment Epithelium Damage Model

Nan Zhang; Xian Zhang; Preston Girardot; Vivian Summers; Jana T Sellers; Ying Li; Micah A Chrenek; John M Nickerson; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4441. doi:

ARVO Annual Meeting Abstract June 2020

Systemic Treatment with Nicotinamide Riboside is Protective in Four Mouse Models of Retinal Degeneration

xian zhang; Nathaniel Henneman; Preston E Girardot; Ying Li; Nan Zhang; Jana T Sellers; Micah A Chrenek; Jiaxing Wang; Eldon E Geisert; Charles Brenner; John M Nickerson; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2753. doi:

Articles May 2020

Drug Tissue Distribution of TUDCA From a Biodegradable Suprachoroidal Implant versus Intravitreal or Systemic Delivery in the Pig Model

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Timothy W. Olsen; Roy B. Dyer; Fukutaro Mano; Jeffrey H. Boatright; Micah A. Chrenek; Daniel Paley; Kathy Wabner; Jenn Schmit; Ju Byung Chae; Jana T. Sellers; Ravinder J. Singh; Timothy S. Wiedmann
TAGS: body tissue, drug or chemical tissue distribution, eye, implants, mechlorethamine, spinal cord injuries, choroid, retina, macula lutea, new mexico
Trans. Vis. Sci. Tech.. 2020; 9(6):11. doi: https://doi.org/10.1167/tvst.9.6.11

Retinal Cell Biology May 2020

Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium

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Varunika Goyal; Christopher DeVera; Virginie Laurent; Jana Sellers; Micah A. Chrenek; David Hicks; Kenkichi Baba; P. Michael Iuvone; Gianluca Tosini
TAGS: dopamine, mice, signal transduction, phagocytosis, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):10. doi: https://doi.org/10.1167/iovs.61.5.10

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Roles of Cone Photoreceptor Connexin-36 in Light Adaptation and Circadian Regulation of the Photopic ERG

Shuo Zhang; Polina Lyubslavsky; Jendayi A Dixon; Micah A Chrenek; Jana Sellers; Christophe Ribelayga; Zhijing Zhang; Xiaobo Xia; P. Michael Iuvone

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1378. doi:

ARVO Annual Meeting Abstract July 2019

Removal of Dopamine 2 Receptor abolishes the daily rhythm of phagocytosis in the mouse RPE.

Varunika Goyal; Christopher De Vera; Virgine Laurent; Kenkichi Baba; Jana Sellers; Micah A Chrenek; David Hicks; P. Michael Iuvone; Gianluca Tosini

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1936. doi:

ARVO Annual Meeting Abstract July 2019

Treatment of retinoblastoma cells with TCP induces dose-dependent cell death

Jennifer Rha; Salma Ferdous; Micah A Chrenek; Maxwell Griffin; Jeffrey H Boatright; Hans E Grossniklaus; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2337. doi:

ARVO Annual Meeting Abstract July 2019

Rpe65 L450 allele increases sensitivity to light damage in C57BL/6J mice

Micah A Chrenek; Jana T Sellers; Kristie Ling Liao; Brooke Still; John M Nickerson; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2358. doi:

ARVO Annual Meeting Abstract July 2019

Interphotoreceptor Retinoid-Binding Protein (IRBP) prevents myopia, independent of mouse genetic backgrounds

Shanu Markand; Somin Kim; Micah A Chrenek; Jeffrey H Boatright; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2367. doi:

ARVO Annual Meeting Abstract July 2019

Removal of the circadian clock gene Bmal1 in the RPE abolishes the daily peak of photoreceptor outer segment disc phagocytosis

Christopher De Vera; Jendayi A Dixon; Micah A Chrenek; Kenkichi Baba; P. Michael Iuvone; Gianluca Tosini

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2377. doi:

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Electrophysiologic and Morphologic Strain Differences in a Low-Dose NaIO 3 -Induced Retinal Pigment Epithelium Damage Model

The effects of light-induced retinal damage (LIRD) in C57BL6/J mouse is mediated by RPE-65 activity

DMSO Protects Retinal Function in Two Mouse Models

Electrophysiological and morphological changes in a low dose sodium iodate induced RPE damage model

Oral supplementary nicotinamide riboside protects function in a model of inherited mouse glaucoma

Long-term Systemic Pentosan Polysulfate Administration Causes Retinal Function Decrease with Changes in Cell Markers

Morphometric Analysis of Retinal Pigment Epithelial Cells From C57BL/6J Mice During Aging

Systemic Treatment With Nicotinamide Riboside Is Protective in a Mouse Model of Light-Induced Retinal Degeneration

Effects of Cone Connexin-36 Disruption on Light Adaptation and Circadian Regulation of the Photopic ERG

Visual defects in mice lacking circadian rhythm function in cone photoreceptors

Optimization of a Retinal Pigment Epithelium Damage Model

Systemic Treatment with Nicotinamide Riboside is Protective in Four Mouse Models of Retinal Degeneration

Drug Tissue Distribution of TUDCA From a Biodegradable Suprachoroidal Implant versus Intravitreal or Systemic Delivery in the Pig Model

Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium

Roles of Cone Photoreceptor Connexin-36 in Light Adaptation and Circadian Regulation of the Photopic ERG

Removal of Dopamine 2 Receptor abolishes the daily rhythm of phagocytosis in the mouse RPE.

Treatment of retinoblastoma cells with TCP induces dose-dependent cell death

Rpe65 L450 allele increases sensitivity to light damage in C57BL/6J mice

Interphotoreceptor Retinoid-Binding Protein (IRBP) prevents myopia, independent of mouse genetic backgrounds

Removal of the circadian clock gene Bmal1 in the RPE abolishes the daily peak of photoreceptor outer segment disc phagocytosis

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