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ARVO Annual Meeting Abstract June 2022

Optic Nerve-Independent Light Perception in Mouse Models of Photoallodynia

Anna Matynia; Sachin Parikh; Jade Suwanwanitch; Michael B Gorin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2612 – F0495. doi:

ARVO Annual Meeting Abstract June 2022

Impaired Cathepsin D evidenced in iPSC-derived RPE cells of STGD1 patients

Eunice Sze Yin Ng; Jane Hu; Katherine Frei; Zhichun Jiang; Michael B Gorin; Anna Matynia; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3894 – A0096. doi:

Articles March 2022

Assessing Variant Causality and Severity Using Retinal Pigment Epithelial Cells Derived from Stargardt Disease Patients

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Anna Matynia; Jun Wang; Sangbae Kim; Yumei Li; Anupama Dimashkie; Zhichun Jiang; Jane Hu; Samuel P. Strom; Roxana A. Radu; Rui Chen; Michael B. Gorin
TAGS: abca4 gene, proteins, retinal pigment cell, stargardt's disease, pathogenicity, idiopathic pneumonia syndrome, alleles
Trans. Vis. Sci. Tech.. 2022; 11(3):33. doi: https://doi.org/10.1167/tvst.11.3.33

Includes: Supplemental Content

Genetics June 2021

Characterization of the Spectrum of Ophthalmic Changes in Patients With Alagille Syndrome

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Mariana Matioli da Palma; Austin D. Igelman; Cristy Ku; Amanda Burr; Jia Yue You; Emily M. Place; Nan-Kai Wang; Jin Kyun Oh; Kari E. Branham; Xinxin Zhang; Jeeyun Ahn; Michael B. Gorin; Byron L. Lam; Cecinio C. Ronquillo; Paul S. Bernstein; Aaron Nagiel; Rachel Huckfeldt; Michelle T. Cabrera; John P. Kelly; Benjamin Bakall; Alessandro Iannaccone; Robert B. Hufnagel; Wadih M. Zein; Robert K. Koenekoop; David G. Birch; Paul Yang; Abigail T. Fahim; Mark E. Pennesi
TAGS: arteriohepatic dysplasia, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):27. doi: https://doi.org/10.1167/iovs.62.7.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

MeCP2-mediated mitochondrial impairment evidenced in Stargardt disease

Arpita R. Dave; Eunice Sze Yin Ng; Zhichun Jiang; Jane G Hu; Michael B Gorin; Anna Matynia; Linsey Stiles; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):269. doi:

ARVO Annual Meeting Abstract June 2021

Membrane attack complex induces RPE cell death in Stargardt Disease

Roxana A Radu; Nermin Kady; Michael B Gorin; Anna Matynia; Jane G Hu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2994. doi:

ARVO Annual Meeting Abstract June 2021

Cathepsin D deficiency in RPE cells mediates Stargardt Disease pathogenesis

Eunice Sze Yin Ng; Jane G Hu; Zhichun Jiang; Michael B Gorin; Anna Matynia; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3113. doi:

Articles May 2021

Assessing the Clinical Utility of Expanded Macular OCTs Using Machine Learning

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Andrew C. Lin; Cecilia S. Lee; Marian Blazes; Aaron Y. Lee; Michael B. Gorin
TAGS: machine learning, open-angle glaucoma, area under the roc curve, diagnostic imaging, datasets
Trans. Vis. Sci. Tech.. 2021; 10(6):32. doi: https://doi.org/10.1167/tvst.10.6.32

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

A Mouse Model of Central Retinal Artery Occlusion

Sachin Parikh; Eduardo Araujo; Michael B Gorin; Missag H Parseghian; Anna Matynia

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1320. doi:

ARVO Annual Meeting Abstract June 2020

Complement Dysregulation is Evidenced in iPSC-derived RPE Cells from Stargardt Disease patients

Jane Hu; Nermin Kady; Ashley Macabasco; Michael B Gorin; Anna Matynia; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1507. doi:

Retina December 2019

Evaluation of the Choroid in Eyes With Retinitis Pigmentosa and Cystoid Macular Edema

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Claudio Iovino; Adrian Au; Assaf Hilely; Sara Violanti; Enrico Peiretti; Michael B. Gorin; David Sarraf
TAGS: choroid, cortical blindness, education, medical, continuing, eye, macular edema, cystoid, retinitis pigmentosa, antidepressive agents, tricyclic, trichloroacetic acid
Invest. Ophthalmol. Vis. Sci.. 2019; 60(15):5000-5006. doi: https://doi.org/10.1167/iovs.19-27300

ARVO Annual Meeting Abstract July 2019

Retinoid recycling is impaired in Stargardt iPSC-derived RPE

Roxana A Radu; Nermin Kady; Jane Hu; Jacqueline Pei; Marcia Lloyd; Dean Bok; Michael B Gorin; Saravanan Karumbayaram; Anna Matynia

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2343. doi:

ARVO Annual Meeting Abstract July 2019

Evaluation of choroidal characteristics and their association with cystoid macular edema in patients with retinitis pigmentosa

CLAUDIO IOVINO; Adrian Au; Sara Violanti; Michael B Gorin; David Sarraf

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4494. doi:

ARVO Annual Meeting Abstract July 2019

Retinal and visual pathway components mediating light- behavior in a mouse model of photoallodynia

Sachin Parikh; Steven Nusinowitz; Michael B Gorin; Anna Matynia

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5261. doi:

ARVO Annual Meeting Abstract July 2019

Reduced expression of “normal” ABCA4 alleles in iPS-derived RPE cells from Stargardt Disease patients

Anna Matynia; Saravanan Karumbayaram; Samuel Strom; Jane Hu; Nermin Kady; Roxana A Radu; Michael B Gorin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):388. doi:

ARVO Annual Meeting Abstract July 2019

Stargardt disease ALK-001 phase 2 clinical trial: 12-month interim data

Hendrik P Scholl; Stephen H Tsang; Christine Nichols Kay; Thomas B. Connor; Michael B Gorin; Paul S Bernstein; Byron L Lam; Zach Strecker; Justin Tyler Zaremba; Gabrielle DeBartolomeo; Ilyas Washington; Leonide Saad

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1336. doi:

ARVO Annual Meeting Abstract July 2019

Anatomical and fixation parameters as predictors of reading speed (RS) in Stargardt Disease

Gabrielle DeBartolomeo; Justin Tyler Zaremba; Zach Strecker; Christine Nichols Kay; Stephen H Tsang; Thomas B. Connor; Michael B Gorin; Paul S Bernstein; Byron L Lam; Ilyas Washington; Hendrik P Scholl; Leonide Saad

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1063. doi:

ARVO Annual Meeting Abstract July 2019

The Visual Function Index (VF-14) reflects a notable loss in Vision-Related Quality of Life (VRQOL) in Stargardt Disease

Justin Tyler Zaremba; Zach Strecker; Gabrielle DeBartolomeo; Stephen H Tsang; Christine Nichols Kay; Thomas B. Connor; Michael B Gorin; Paul S Bernstein; Byron L Lam; Ilyas Washington; Hendrik P Scholl; Leonide Saad

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4970. doi:

ARVO Annual Meeting Abstract July 2018

A novel mutation in KIF3B in a family with dominant retinitis pigmentosa and polydactyly

Stephen P Daiger; Lori S Sullivan; Sara J Bowne; Elizabeth L Cadena; Kinga Maria Bujakowska; Eric A Pierce; Michael B Gorin; Xénia Latypova; Erica E Davis; Nicholas Katsanis; Ludovic Martin; Laurence Legeai-Mallet; Benjamin Cogne; Stéphane Bezieau; Thomas Besnard; Bertrand Isidor

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):47. doi:

ARVO Annual Meeting Abstract July 2018

Rod- and Cone- Mediated Dark-Adaptation Kinetics in Pre-Clinical Age-Related Macular Degeneration (AMD)

Emma Stackpole; Yvette Conley; Mark Perlin; Michael B Gorin; Steven Nusinowitz

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1259. doi:

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Optic Nerve-Independent Light Perception in Mouse Models of Photoallodynia

Impaired Cathepsin D evidenced in iPSC-derived RPE cells of STGD1 patients

Assessing Variant Causality and Severity Using Retinal Pigment Epithelial Cells Derived from Stargardt Disease Patients

Characterization of the Spectrum of Ophthalmic Changes in Patients With Alagille Syndrome

MeCP2-mediated mitochondrial impairment evidenced in Stargardt disease

Membrane attack complex induces RPE cell death in Stargardt Disease

Cathepsin D deficiency in RPE cells mediates Stargardt Disease pathogenesis

Assessing the Clinical Utility of Expanded Macular OCTs Using Machine Learning

A Mouse Model of Central Retinal Artery Occlusion

Complement Dysregulation is Evidenced in iPSC-derived RPE Cells from Stargardt Disease patients

Evaluation of the Choroid in Eyes With Retinitis Pigmentosa and Cystoid Macular Edema

Retinoid recycling is impaired in Stargardt iPSC-derived RPE

Evaluation of choroidal characteristics and their association with cystoid macular edema in patients with retinitis pigmentosa

Retinal and visual pathway components mediating light- behavior in a mouse model of photoallodynia

Reduced expression of “normal” ABCA4 alleles in iPS-derived RPE cells from Stargardt Disease patients

Stargardt disease ALK-001 phase 2 clinical trial: 12-month interim data

Anatomical and fixation parameters as predictors of reading speed (RS) in Stargardt Disease

The Visual Function Index (VF-14) reflects a notable loss in Vision-Related Quality of Life (VRQOL) in Stargardt Disease

A novel mutation in KIF3B in a family with dominant retinitis pigmentosa and polydactyly

Rod- and Cone- Mediated Dark-Adaptation Kinetics in Pre-Clinical Age-Related Macular Degeneration (AMD)

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