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ARVO Annual Meeting Abstract June 2025

In-depth phenotypic study of a Novel Autosomal Dominant RPE65-related Retinal Dystrophy

Filip Van den Broeck; Eline Van Vooren; Manon Van Haute; Marieke De Bruyne; Van De Sompele Stijn; Mattias Van Heetvelde; Quinten Mahieu; Sheetal Uppal; Eugenia Poliakov; T. Michael Redmond; Miriam Bauwens; Elfride De Baere; Julie De Zaeytijd; Bart Peter Leroy

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3122.

ARVO Annual Meeting Abstract June 2025

Plasticity of ARPE-19 RPE cell line is evidenced by proteomics analyses of cultures in grown in media with different supplementations.

Gleysin Cabrera-Herrera; Todd Duncan; Samuel William; Eugenia Poliakov; Sheetal Uppal; Cynthia Jaworski; Yan Li; Chenyue Wang; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3056.

ARVO Annual Meeting Abstract June 2024

A novel RPE65 -related dominant retinopathy caused by founder variant c.1555G>A p.(Glu519Lys) enriched in Belgian patients with a recognizable pattern dystrophy spectrum

Eline Van Vooren; Filip Van Den Broeck; Marieke De Bruyne; Quinten Mahieu; Sheetal Uppal; Eugenia Poliakov; T. Michael Redmond; Julie De Zaeytijd; Bart Peter Leroy; Miriam Bauwens; Elfride De Baere

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1517.

ARVO Annual Meeting Abstract June 2024

The functional significance of pathogenic variants in RPE65 107-125 amphipathic helix in RPE65-membrane recognition and binding

Sheetal Uppal; Eugenia Poliakov; Susan Gentleman; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1276.

ARVO Annual Meeting Abstract June 2024

LINC00276 interacts with hnRNPL and activates the Wnt/β-catenin pathway to promote differentiation in RPE cells

Samuel William; Lisa Jenkins; Sheetal Uppal; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4706.

ARVO Annual Meeting Abstract June 2023

The long noncoding RNA LINC00276 mediates RPE differentiation through its interaction with hnRNPL

Samuel William; Camasamudram Vijayasarathy; Lisa Jenkins; Sheetal Uppal; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4474.

ARVO Annual Meeting Abstract June 2023

Dissecting the entry mechanisms of SARS-CoV-2 in ARPE-19 cells

Sheetal Uppal; Olga A. Postnikova; Eugenia Poliakov; Igor Rogozin; Rafael Villasmil; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4431.

ARVO Annual Meeting Abstract June 2023

Human iPSC-derived Microglia Cells Show Integration into Microglia-depleted Mouse Retina and Recapitulate Features of Endogenous Microglia

Wenxin Ma; Lian Zhao; Biying Xu; Robert Fariss; T. Michael Redmond; Wei Li; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4339.

ARVO Annual Meeting Abstract June 2022

Inhibition of Sodium Iodate-Induced Apoptosis in Human RPE by the Stearoyl Coenzyme A Desaturase Inhibitor Sterculic acid

William Samuel; Camasamudram Vijayasarathy; Sheetal Uppal; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3906 – A0108.

ARVO Annual Meeting Abstract June 2022

An amphipathic helix directs membrane binding and function of RPE65 retinol isomerase

Sheetal Uppal; Eugenia Poliakov; Susan Gentleman; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3899 – A0101.

ARVO Annual Meeting Abstract June 2021

Long non-coding RNA LINC00276 may encode micropeptides to maintain cellular homeostasis in human retinal pigment epithelial cells

William Samuel; Sheetal Uppal; Olga Postnikova; Igor Rogozin; Eugenia Poliakov; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2962.

ARVO Annual Meeting Abstract June 2020

Amphipathic Helix Residues Influence RPE65 Protein Palmitoylation, Localization and Function

Sheetal Uppal; Eugenia Poliakov; Susan Gentleman; Thomas Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1518.

ARVO Annual Meeting Abstract June 2020

Long Non-coding RNA LINC00276 is involved in the differentiation of human retinal pigment epithelial cells

William Samuel; Olga Postnikova; Cynthia Jaworski; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1534.

ARVO Annual Meeting Abstract June 2020

Processing of visual cycle retinoids in iPSC-derived RPE from Albinism patients

Aman George; Todd Duncan; Ruchi Sharma; Tyler Pfister; Charles DeYoung; Kapil Bharti; T. Michael Redmond; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4156.

ARVO Annual Meeting Abstract July 2019

Altered Expression of LINC00276 is Associated with Retinal Pigment Epithelial Dysfunction Induced by Proinflammatory Cytokines

William Samuel; R.Krishnan Kutty; Chandra N Nagineni; Olga A Postnikova; Cynthia Jaworski; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2386.

ARVO Annual Meeting Abstract July 2019

CIB2 is essential for autophagy in the retinal pigment epithelium and visual function

Zubair Ahmed; Saumil Sethna; Patrick A. Scott; Arnaud P. Giese; Todd Duncan; Sheikh Riazuddin; T Michael Redmond; Steven L Bernstein; Saima Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3868.

ARVO Annual Meeting Abstract July 2018

Mapping and analysis of S-palmitoylation sites on RPE65

T. Michael Redmond; Sheetal Uppal; Eugenia Poliakov; Susan Gentleman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4518.

ARVO Annual Meeting Abstract July 2018

Long Non-coding RNA LINC00276 is involved in the differentiation of human retinal pigment epithelial cells

William Samuel; Todd Duncan; Olga Postnikova; Cynthia Jaworski; R Krishnan Kutty; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5382.

ARVO Annual Meeting Abstract June 2017

Interferon-γ increases expression of the long non-Coding RNA BANCR in retinal pigment epithelial cells by activating JAK/STAT signaling pathway

R Krishnan Kutty; William Samuel; Cynthia Jaworski; Olga Postnikova; Todd Duncan; Chandrasekharam N Nagineni; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):592.

ARVO Annual Meeting Abstract June 2017

Microarray transcriptome analysis of the inflammatory response of retinal pigment epithelial cells

William Samuel; R Krishnan Kutty; Cynthia Jaworski; Todd Duncan; T. Michael Redmond; Paul Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):628.

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In-depth phenotypic study of a Novel Autosomal Dominant RPE65-related Retinal Dystrophy

Plasticity of ARPE-19 RPE cell line is evidenced by proteomics analyses of cultures in grown in media with different supplementations.

A novel RPE65 -related dominant retinopathy caused by founder variant c.1555G>A p.(Glu519Lys) enriched in Belgian patients with a recognizable pattern dystrophy spectrum

The functional significance of pathogenic variants in RPE65 107-125 amphipathic helix in RPE65-membrane recognition and binding

LINC00276 interacts with hnRNPL and activates the Wnt/β-catenin pathway to promote differentiation in RPE cells

The long noncoding RNA LINC00276 mediates RPE differentiation through its interaction with hnRNPL

Dissecting the entry mechanisms of SARS-CoV-2 in ARPE-19 cells

Human iPSC-derived Microglia Cells Show Integration into Microglia-depleted Mouse Retina and Recapitulate Features of Endogenous Microglia

Inhibition of Sodium Iodate-Induced Apoptosis in Human RPE by the Stearoyl Coenzyme A Desaturase Inhibitor Sterculic acid

An amphipathic helix directs membrane binding and function of RPE65 retinol isomerase

Long non-coding RNA LINC00276 may encode micropeptides to maintain cellular homeostasis in human retinal pigment epithelial cells

Amphipathic Helix Residues Influence RPE65 Protein Palmitoylation, Localization and Function

Long Non-coding RNA LINC00276 is involved in the differentiation of human retinal pigment epithelial cells

Processing of visual cycle retinoids in iPSC-derived RPE from Albinism patients

Altered Expression of LINC00276 is Associated with Retinal Pigment Epithelial Dysfunction Induced by Proinflammatory Cytokines

CIB2 is essential for autophagy in the retinal pigment epithelium and visual function

Mapping and analysis of S-palmitoylation sites on RPE65

Long Non-coding RNA LINC00276 is involved in the differentiation of human retinal pigment epithelial cells

Interferon-γ increases expression of the long non-Coding RNA BANCR in retinal pigment epithelial cells by activating JAK/STAT signaling pathway

Microarray transcriptome analysis of the inflammatory response of retinal pigment epithelial cells

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