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Meeting Abstract (9)
Journal Articles (3)

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Investigative Ophthalmology & Visual Science (12)

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ARVO Annual Meeting Abstract (9)
Letters to the Editor (1)
Retina (1)
Translational (1)

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Eye Anatomy and Disorders (3)
Nanotechnology and Regenerative Medicine (3)
Retina (3)
Genetics (1)
Translational Research (1)

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photoreceptors (3)
transplantation (3)
mice (2)
cytoplasm (1)
donors (1)
meckel-gruber syndrome (1)
organoids (1)
progressive cone-rod dystrophy (1)
retina (1)
retinal pigment cell (1)

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ARVO Annual Meeting Abstract June 2024

Characterization of a mouse model of complex outer retinal pathology by injection of HBEGF and TNF for photoreceptor transplantation

Rodrigo Ramos Acevedo; Robert Münch; MIKE-OLIVER O KARL; Marius Ader

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5009.

ARVO Annual Meeting Abstract June 2023

Preclinical human model for retinal cell therapy: Pathology dependent integration of photoreceptor transplants into human retina organoid hosts

Felix Wagner; Roberto Carrera; Thomas Kurth; Stylianos Michalakis; Deniz Dalkara; Mike O. Karl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3858.

ARVO Annual Meeting Abstract June 2022

Donor-host interactions support incorporation, polarization and maturation of human photoreceptors transplanted into a cone-degeneration mouse model

Karen Tessmer; Sylvia Jane Gasparini; Miriam Reh; Stephanie Wieneke; Madalena Carido; Manuela Völkner; Oliver Borsch; Anka Swiersy; Marta Zuzic; Olivier Goureau; Thomas Kurth; Volker Busskamp; Günther Zeck; Mike O Karl; Marius Ader

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1115.

ARVO Annual Meeting Abstract June 2021

HiPSC-derived cones incorporate, mature and survive long-term in a mouse model of cone-degeneration

Sylvia Jane Gasparini; Karen Tessmer; Madalena Carido; Oliver Borsch; Stephanie Wieneke; Anka Kempe; Marta Zusic; Manuela Völkner; Mike O Karl; Volker Busskamp; Marius Ader

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3305.

ARVO Annual Meeting Abstract July 2019

Forward programming of photoreceptors from human induced pluripotent stem cells

Marta Zuzic; Anka Kempe; Mike O. Karl; Volker Busskamp

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1008.

ARVO Annual Meeting Abstract July 2019

Transcriptomic assessing and guiding DSB repair pathway activity towards precise genomic engineering of post-mitotic neurons

Giovanni Pasquini; Anka Kempe; Mike O. Karl; Knut Stieger; Volker Busskamp

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3123.

ARVO Annual Meeting Abstract July 2018

Subretinal transplantation of human induced pluripotent stem cell-derived retinal pigment epithelium (hiPS-RPE) into pigs.

Dirk Sandner; Marlene Stein; Dierk Wittig; Seba Almedawar; Helmut Sachs; Martin Scharffenberg; Roland Jung; Lutz Pillunat; Elly Tanaka; Mike O. Karl; Marius Ader

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):545.

ARVO Annual Meeting Abstract June 2017

Retinal cell death dependent reactive proliferative gliosis in the mouse retina

Sheik Pran Babu Sardar Pasha; Münch Robert; Schäfer Patrick; Oertel Peter; Mike O Karl

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5387.

Letters to the Editor October 2016

Author Response: Possibility of Cytoplasmic Transportation Between Donor–Host Cell Following Photoreceptor Transplantation

PDF

Tiago Santos-Ferreira; Manuela Völkner; Oliver Borsch; Jochen Haas; Peter Cimalla; Praveen Vasudevan; Peter Carmeliet; Denis Corbeil; Stylianos Michalakis; Edmund Koch; Mike O Karl; Marius Ader
TAGS: cytoplasm, donors, photoreceptors, transplantation, transportation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5336-5337. https://doi.org/10.1167/iovs.16-20687

Retina June 2016

Stem Cell–Derived Photoreceptor Transplants Differentially Integrate Into Mouse Models of Cone-Rod Dystrophy

PDF

Tiago Santos-Ferreira; Manuela Völkner; Oliver Borsch; Jochen Haas; Peter Cimalla; Praveen Vasudevan; Peter Carmeliet; Denis Corbeil; Stylianos Michalakis; Edmund Koch; Mike O. Karl; Marius Ader
TAGS: meckel-gruber syndrome, mice, photoreceptors, rod photoreceptors, transplantation, progressive cone-rod dystrophy, retinitis pigmentosa, stem cells, retina, organoids
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3509-3520. https://doi.org/10.1167/iovs.16-19087

Includes: Multimedia, Supplemental Content

Translational Research August 2014

Characterization of a Mouse Model With Complete RPE Loss and Its Use for RPE Cell Transplantation

PDF

Madalena Carido; Yu Zhu; Kai Postel; Boris Benkner; Peter Cimalla; Mike O. Karl; Thomas Kurth; François Paquet-Durand; Edmund Koch; Thomas A. Münch; Elly M. Tanaka; Marius Ader
TAGS: mice, retinal pigment cell, tissue degeneration, transplantation, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5431-5444. https://doi.org/10.1167/iovs.14-14325

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

Muller Glia Proliferative Plasticity is Age-Dependent

Mike O. Karl; Sam Sudar; Thomas A. Reh

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2244.

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