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Genetics August 2021

Phenotypic Consequences of the GJD2 Risk Genotype in Myopia Development

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Annechien E. G. Haarman; Clair A. Enthoven; Milly S. Tedja; Jan R. Polling; J. Willem L. Tideman; Jan E. E. Keunen; Camiel J. F. Boon; Janine F. Felix; H. Raat; Annette J. M. Geerards; Gregorius P. M. Luyten; Gwyneth A. van Rijn; Virginie J. M. Verhoeven; Caroline C. W. Klaver
TAGS: adult, genes, genotype, myopia, phenotype, child, refractive errors, biometry
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):16. https://doi.org/10.1167/iovs.62.10.16

Includes: Supplemental Content

Special Issue April 2021

IMI 2021 Yearly Digest

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Monica Jong; Jost B. Jonas; James S. Wolffsohn; David A. Berntsen; Pauline Cho; Danielle Clarkson-Townsend; Daniel I. Flitcroft; Kate L. Gifford; Annechien E. G. Haarman; Machelle T. Pardue; Kathryn Richdale; Padmaja Sankaridurg; Milly S. Tedja; Christine F. Wildsoet; Joan E. Bailey-Wilson; Jeremy A. Guggenheim; Christopher J. Hammond; Jaakko Kaprio; Stuart MacGregor; David A. Mackey; Anthony M. Musolf; Caroline C. W. Klaver; Virginie J. M. Verhoeven; Veronique Vitart; Earl L. Smith, III
TAGS: myopia
Invest. Ophthalmol. Vis. Sci.. 2021; 62(5):7. https://doi.org/10.1167/iovs.62.5.7

Includes: Supplemental Content

Review April 2020

The Complications of Myopia: A Review and Meta-Analysis

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Annechien E. G. Haarman; Clair A. Enthoven; J. Willem L. Tideman; Milly S. Tedja; Virginie J. M. Verhoeven; Caroline C. W. Klaver
TAGS: meta-analysis, myopia
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):49. https://doi.org/10.1167/iovs.61.4.49

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2020

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

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Alfred Pozarickij; Clair A. Enthoven; Neema Ghorbani Mojarrad; Denis Plotnikov; Milly S. Tedja; Annechien E.G. Haarman; J. Willem L. Tideman; Jan Roelof Polling; Kate Northstone; Cathy Williams; Caroline C. W. Klaver; Jeremy A. Guggenheim
TAGS: alspac study, buffers, child, environmental factors, genetics, myopia, refractive errors, risk factors, parent, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):41. https://doi.org/10.1167/iovs.61.2.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Caroline C W Klaver; Milly S. Tedja; Xikun Han; Virginie JM Verhoeven; Nick Ericksson; Nick Furlotte; Najaf Amin; Cornelia van Duijn; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3143.

ARVO Annual Meeting Abstract July 2019

Grading of retinal complications in high myopia occurring in Europeans

Annechien Haarman; Milly S. Tedja; Corina Brussee; Gwyneth A van Rijn; Johannes R. Vingerling; Jan Keunen; Camiel Boon; Annette J.M. Geerards; Gregorius P.M. Luyten; Virginie JM Verhoeven; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4349.

Genetics July 2019

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

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Adriana I. Iglesias; Jue Sheng Ong; Anthony P. Khawaja; Puya Gharahkhani; Milly S. Tedja; Virginie J. M. Verhoeven; Pieter W. M. Bonnemaijer; Roger C. W. Wolfs; Terri L. Young; Nomdo M. Jansonius; Jamie E. Craig; Dwight Stambolian; Cornelia M. van Duijn; Stuart MacGregor; Caroline C. W. Klaver; for the International Glaucoma Genetics Consortium (IGGC) and Consortium for Refractive Error and Myopia (CREAM)
TAGS: myopia, open-angle glaucoma, genetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3142-3149. https://doi.org/10.1167/iovs.18-26231

Includes: Supplemental Content

Special Issue February 2019

IMI – Myopia Genetics Report

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Milly S. Tedja; Annechien E. G. Haarman; Magda A. Meester-Smoor; Jaakko Kaprio; David A. Mackey; Jeremy A. Guggenheim; Christopher J. Hammond; Virginie J. M. Verhoeven; Caroline C. W. Klaver; for the CREAM Consortium
TAGS: genetics, myopia, genome-wide association study, universities, refractive errors, genes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M89-M105. https://doi.org/10.1167/iovs.18-25965

ARVO Annual Meeting Abstract July 2018

Risk variances of refractive error and axial length explained by polygenic risk scores of spherical equivalents

Clair Enthoven; Adriana I Iglesias; Milly S. Tedja; Willem Tideman; Jan Roelof Polling; Virginie JM Verhoeven; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):700.

ARVO Annual Meeting Abstract July 2018

Post-GWAS analysis on the molecular machinery in refractive error development

Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Christopher J Hammond; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1821.

ARVO Annual Meeting Abstract June 2017

Newly identified genes for refractive error and risk of myopia

Virginie JM Verhoeven; Adriana I Iglesias; Milly S. Tedja; Elisabeth M. van Leeuwen; Pirro G Hysi; Robert Wojciechowski; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):181.

ARVO Annual Meeting Abstract June 2017

Light processing and regulators are important mechanisms in refractive error

Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Adriana I Iglesias; Roxanna Haak; Peter J Van der Spek; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1225.

ARVO Annual Meeting Abstract June 2017

Post-GWAS analysis approaches uncover dozens of novel genes associated with myopic refractive error

Stuart MacGregor; Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Christopher J Hammond; Adriana I Iglesias; David A Mackey; Cornelia van Duijn; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1226.

ARVO Annual Meeting Abstract June 2017

Meta-analyses of two large GWAS show a high genetic correlation between myopia age-at-onset and refractive error during adulthood and older age.

Robert Wojciechowski; Pirro G Hysi; Milly S. Tedja; Virginie JM Verhoeven; Jeremy A Guggenheim; Stuart MacGregor; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1227.

ARVO Annual Meeting Abstract September 2016

Genome-Wide Association Study Identifies Novel Genes Associated with High Myopia in the General Population

Pirro G Hysi; Virginie JM Verhoeven; Robert Wojciechowski; Milly S Tedja; René Hoehn; Caroline C W Klaver; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

MicroRNAs: regulators in the development of refractive errors and myopia

Milly S Tedja; Mohsen Ghanbari; Magda A. Meester; Abbas Dehghan; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4791.

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Phenotypic Consequences of the GJD2 Risk Genotype in Myopia Development

IMI 2021 Yearly Digest

The Complications of Myopia: A Review and Meta-Analysis

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Grading of retinal complications in high myopia occurring in Europeans

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

IMI – Myopia Genetics Report

Risk variances of refractive error and axial length explained by polygenic risk scores of spherical equivalents

Post-GWAS analysis on the molecular machinery in refractive error development

Newly identified genes for refractive error and risk of myopia

Light processing and regulators are important mechanisms in refractive error

Post-GWAS analysis approaches uncover dozens of novel genes associated with myopic refractive error

Meta-analyses of two large GWAS show a high genetic correlation between myopia age-at-onset and refractive error during adulthood and older age.

Genome-Wide Association Study Identifies Novel Genes Associated with High Myopia in the General Population

MicroRNAs: regulators in the development of refractive errors and myopia

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