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Genetics August 2021

Phenotypic Consequences of the GJD2 Risk Genotype in Myopia Development

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Annechien E. G. Haarman; Clair A. Enthoven; Milly S. Tedja; Jan R. Polling; J. Willem L. Tideman; Jan E. E. Keunen; Camiel J. F. Boon; Janine F. Felix; H. Raat; Annette J. M. Geerards; Gregorius P. M. Luyten; Gwyneth A. van Rijn; Virginie J. M. Verhoeven; Caroline C. W. Klaver
TAGS: adult, genes, genotype, myopia, phenotype, child, refractive errors, biometry
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):16. doi: https://doi.org/10.1167/iovs.62.10.16

Includes: Supplemental Content

Special Issue April 2021

IMI 2021 Yearly Digest

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Monica Jong; Jost B. Jonas; James S. Wolffsohn; David A. Berntsen; Pauline Cho; Danielle Clarkson-Townsend; Daniel I. Flitcroft; Kate L. Gifford; Annechien E. G. Haarman; Machelle T. Pardue; Kathryn Richdale; Padmaja Sankaridurg; Milly S. Tedja; Christine F. Wildsoet; Joan E. Bailey-Wilson; Jeremy A. Guggenheim; Christopher J. Hammond; Jaakko Kaprio; Stuart MacGregor; David A. Mackey; Anthony M. Musolf; Caroline C. W. Klaver; Virginie J. M. Verhoeven; Veronique Vitart; Earl L. Smith, III
TAGS: myopia
Invest. Ophthalmol. Vis. Sci.. 2021; 62(5):7. doi: https://doi.org/10.1167/iovs.62.5.7

Includes: Supplemental Content

Review April 2020

The Complications of Myopia: A Review and Meta-Analysis

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Annechien E. G. Haarman; Clair A. Enthoven; J. Willem L. Tideman; Milly S. Tedja; Virginie J. M. Verhoeven; Caroline C. W. Klaver
TAGS: meta-analysis, myopia
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):49. doi: https://doi.org/10.1167/iovs.61.4.49

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2020

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

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Alfred Pozarickij; Clair A. Enthoven; Neema Ghorbani Mojarrad; Denis Plotnikov; Milly S. Tedja; Annechien E.G. Haarman; J. Willem L. Tideman; Jan Roelof Polling; Kate Northstone; Cathy Williams; Caroline C. W. Klaver; Jeremy A. Guggenheim
TAGS: alspac study, buffers, child, environmental factors, genetics, myopia, refractive errors, risk factors, parent, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):41. doi: https://doi.org/10.1167/iovs.61.2.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Caroline C W Klaver; Milly S. Tedja; Xikun Han; Virginie JM Verhoeven; Nick Ericksson; Nick Furlotte; Najaf Amin; Cornelia van Duijn; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3143. doi:

ARVO Annual Meeting Abstract July 2019

Grading of retinal complications in high myopia occurring in Europeans

Annechien Haarman; Milly S. Tedja; Corina Brussee; Gwyneth A van Rijn; Johannes R. Vingerling; Jan Keunen; Camiel Boon; Annette J.M. Geerards; Gregorius P.M. Luyten; Virginie JM Verhoeven; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4349. doi:

Genetics July 2019

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

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Adriana I. Iglesias; Jue Sheng Ong; Anthony P. Khawaja; Puya Gharahkhani; Milly S. Tedja; Virginie J. M. Verhoeven; Pieter W. M. Bonnemaijer; Roger C. W. Wolfs; Terri L. Young; Nomdo M. Jansonius; Jamie E. Craig; Dwight Stambolian; Cornelia M. van Duijn; Stuart MacGregor; Caroline C. W. Klaver; for the International Glaucoma Genetics Consortium (IGGC) and Consortium for Refractive Error and Myopia (CREAM)
TAGS: myopia, open-angle glaucoma, genetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3142-3149. doi: https://doi.org/10.1167/iovs.18-26231

Includes: Supplemental Content

Special Issue February 2019

IMI – Myopia Genetics Report

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Milly S. Tedja; Annechien E. G. Haarman; Magda A. Meester-Smoor; Jaakko Kaprio; David A. Mackey; Jeremy A. Guggenheim; Christopher J. Hammond; Virginie J. M. Verhoeven; Caroline C. W. Klaver; for the CREAM Consortium
TAGS: genetics, myopia, genome-wide association study, universities, refractive errors, genes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M89-M105. doi: https://doi.org/10.1167/iovs.18-25965

ARVO Annual Meeting Abstract July 2018

Risk variances of refractive error and axial length explained by polygenic risk scores of spherical equivalents

Clair Enthoven; Adriana I Iglesias; Milly S. Tedja; Willem Tideman; Jan Roelof Polling; Virginie JM Verhoeven; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):700. doi:

ARVO Annual Meeting Abstract July 2018

Post-GWAS analysis on the molecular machinery in refractive error development

Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Christopher J Hammond; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1821. doi:

ARVO Annual Meeting Abstract June 2017

Light processing and regulators are important mechanisms in refractive error

Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Adriana I Iglesias; Roxanna Haak; Peter J Van der Spek; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1225. doi:

ARVO Annual Meeting Abstract June 2017

Post-GWAS analysis approaches uncover dozens of novel genes associated with myopic refractive error

Stuart MacGregor; Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Christopher J Hammond; Adriana I Iglesias; David A Mackey; Cornelia van Duijn; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1226. doi:

ARVO Annual Meeting Abstract June 2017

Meta-analyses of two large GWAS show a high genetic correlation between myopia age-at-onset and refractive error during adulthood and older age.

Robert Wojciechowski; Pirro G Hysi; Milly S. Tedja; Virginie JM Verhoeven; Jeremy A Guggenheim; Stuart MacGregor; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1227. doi:

ARVO Annual Meeting Abstract June 2017

Newly identified genes for refractive error and risk of myopia

Virginie JM Verhoeven; Adriana I Iglesias; Milly S. Tedja; Elisabeth M. van Leeuwen; Pirro G Hysi; Robert Wojciechowski; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):181. doi:

ARVO Annual Meeting Abstract September 2016

Genome-Wide Association Study Identifies Novel Genes Associated with High Myopia in the General Population

Pirro G Hysi; Virginie JM Verhoeven; Robert Wojciechowski; Milly S Tedja; René Hoehn; Caroline C W Klaver; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

MicroRNAs: regulators in the development of refractive errors and myopia

Milly S Tedja; Mohsen Ghanbari; Magda A. Meester; Abbas Dehghan; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4791. doi:

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Phenotypic Consequences of the GJD2 Risk Genotype in Myopia Development

IMI 2021 Yearly Digest

The Complications of Myopia: A Review and Meta-Analysis

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Grading of retinal complications in high myopia occurring in Europeans

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

IMI – Myopia Genetics Report

Risk variances of refractive error and axial length explained by polygenic risk scores of spherical equivalents

Post-GWAS analysis on the molecular machinery in refractive error development

Light processing and regulators are important mechanisms in refractive error

Post-GWAS analysis approaches uncover dozens of novel genes associated with myopic refractive error

Meta-analyses of two large GWAS show a high genetic correlation between myopia age-at-onset and refractive error during adulthood and older age.

Newly identified genes for refractive error and risk of myopia

Genome-Wide Association Study Identifies Novel Genes Associated with High Myopia in the General Population

MicroRNAs: regulators in the development of refractive errors and myopia

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