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ARVO Annual Meeting Abstract June 2025

Trabecular meshwork and Schlemm’s canal cells show cell specific physiological properties subjected to mechanical stress

Monika Lakk; Christopher N Rudzitis; Ayushi Singh; Samuel Herberg; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):812.

ARVO Annual Meeting Abstract June 2025

Modulatory effect of mechanosensors on retinal ganglion cell physiology

John Cheriyan; Suva Roy; Frans Vinberg; Monika Lakk; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4948.

ARVO Annual Meeting Abstract June 2025

INVESTIGATING COUPLED BIOMECHANICAL EFFECTS ON TRABECULAR MESHWORK CELLS USING A HYDROGEL-INTEGRATED GLAUCOMA CHIP

Kanghoon Choi; Minju Kim; Monika Lakk; Fiona McDonnell; David Krizaj; Jungkyu (Jay) Kim

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6234.

ARVO Annual Meeting Abstract June 2025

TRPV4 Signaling Contributes to TGFβ2-Induced Transcriptional Remodeling in Human Trabecular Meshwork Cells

Christopher N Rudzitis; Monika Lakk; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3004.

ARVO Annual Meeting Abstract June 2025

TRPV4 and TREK1 regulate IOP dynamics and pathology in TGFb-induced ocular hypertension

Sarah Redmon; Christopher N Rudzitis; Monika Lakk; Yun-Ting Tseng; Fiona McDonnell; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3003.

ARVO Annual Meeting Abstract June 2025

Functional expression of Piezo1 in the trabecular meshwork and retinal TRPV4 regulate pressure transduction in vertebrate

Yun-Ting Tseng; Monika Lakk; Christopher N Rudzitis; Sarah Redmon; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3002.

ARVO Annual Meeting Abstract June 2025

Mitochondrial response to activation of mechanosensitive ion channels in trabecular meshwork cells

Jus Zavbi; Monika Lakk; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2988.

ARVO Annual Meeting Abstract June 2024

TRPV4 and Piezo1 activation in the trabecular meshwork contributes to pressure-induced RGC degeneration

Yun-Ting Tseng; Monika Lakk; Sarah Nicole Redmon; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1199.

ARVO Annual Meeting Abstract June 2024

TRPV4 and TREK1 differentially regulate IOP and pathology in a mouse model of steroid-induced glaucoma

Sarah Redmon; Christopher Rudzitis; Monika Lakk; Yun-Ting Tseng; Jordan Searle; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3573.

ARVO Annual Meeting Abstract June 2024

Selective ablation of pressure sensors modulates intraocular pressure and alters the molecular, physiological and biomechanical properties of mouse trabecular meshwork cells

Monika Lakk; Yun-Ting Tseng; Christopher Rudzitis; Terete Borras; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4263.

ARVO Annual Meeting Abstract June 2024

Biochemical vs mechanical IOP regulation: Interactions between mechanochannels and signaling cytokines in the Trabecular Meshwork

Christopher Rudzitis; Monika Lakk; Sarah Redmon; Ayushi Singh; Samuel Herberg; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5156.

ARVO Annual Meeting Abstract June 2023

TRPV4 expression in the healthy and glaucomatous mouse retina

Denisa Kirdajova; Monika Lakk; Felix Vazquez-Chona; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1019.

ARVO Annual Meeting Abstract June 2023

Trabecular meshwork cells show phenotypical and physiological changes in primary-open angle glaucoma

Monika Lakk; Jackson M Baumann; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3463.

ARVO Annual Meeting Abstract June 2023

TRPV4 contributes to stiffness-induced upregulation of YAP in the Trabecular Meshwork

Christopher N. Rudzitis; Monika Lakk; Brenan Cullimore; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3452.

ARVO Annual Meeting Abstract June 2022

TRPV4 involvement in inflammation and tissue damage in corneal epithelium

Luka Lapajne; Monika Lakk; Marko Hawlina; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3244 – A0279.

ARVO Annual Meeting Abstract June 2021

Developing novel TRPV4 antagonists for the treatment of glaucoma

Sarah Redmon; Monika Lakk; Tam Phuong; Christopher Reilly; Paul Sebahar; Ryan Looper; Christine Harman; András Komáromy; Alejandra Bosco; Monica L Vetter; Oleg Yarishkin; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2772.

ARVO Annual Meeting Abstract June 2020

Cholesterol regulates TRPV4-dependent signaling in the trabecular meshwork

David Krizaj; Trine Lisberg Toft-Bertelsen; Aruna gorusupudi; Nanna Macaulay; Paul S Bernstein; Monika Lakk

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3424.

Physiology and Pharmacology April 2020

Polymodal Sensory Transduction in Mouse Corneal Epithelial Cells

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Luka Lapajne; Monika Lakk; Oleg Yarishkin; Lara Gubeljak; Marko Hawlina; David Križaj
TAGS: calcium, chronic exertional compartment syndrome, cornea, corneal epithelial cells, epithelium, mechanotransduction, cellular, mice, trpv1 receptor, diagnostic imaging, edema
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):2. https://doi.org/10.1167/iovs.61.4.2

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Corneal mechanotransduction drives TRPV4-dependent release of the transmitter ATP

Luka Lapajne; Monika Lakk; Lara Gubeljak; Oleg Yarishkin; Marko Hawlina; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):916.

ARVO Annual Meeting Abstract July 2019

The Mechanogated PIEZO1 Channel Regulates Ca 2+ Homeostasis and Formation of Focal Contacts in Human Trabecular Meshwork Cells

Oleg Yarishkin; Tam T.T. Phuong; Jackson M Baumann; Sarah Redmon; Monika Lakk; David Krizaj

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2190.

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Trabecular meshwork and Schlemm’s canal cells show cell specific physiological properties subjected to mechanical stress

Modulatory effect of mechanosensors on retinal ganglion cell physiology

INVESTIGATING COUPLED BIOMECHANICAL EFFECTS ON TRABECULAR MESHWORK CELLS USING A HYDROGEL-INTEGRATED GLAUCOMA CHIP

TRPV4 Signaling Contributes to TGFβ2-Induced Transcriptional Remodeling in Human Trabecular Meshwork Cells

TRPV4 and TREK1 regulate IOP dynamics and pathology in TGFb-induced ocular hypertension

Functional expression of Piezo1 in the trabecular meshwork and retinal TRPV4 regulate pressure transduction in vertebrate

Mitochondrial response to activation of mechanosensitive ion channels in trabecular meshwork cells

TRPV4 and Piezo1 activation in the trabecular meshwork contributes to pressure-induced RGC degeneration

TRPV4 and TREK1 differentially regulate IOP and pathology in a mouse model of steroid-induced glaucoma

Selective ablation of pressure sensors modulates intraocular pressure and alters the molecular, physiological and biomechanical properties of mouse trabecular meshwork cells

Biochemical vs mechanical IOP regulation: Interactions between mechanochannels and signaling cytokines in the Trabecular Meshwork

TRPV4 expression in the healthy and glaucomatous mouse retina

Trabecular meshwork cells show phenotypical and physiological changes in primary-open angle glaucoma

TRPV4 contributes to stiffness-induced upregulation of YAP in the Trabecular Meshwork

TRPV4 involvement in inflammation and tissue damage in corneal epithelium

Developing novel TRPV4 antagonists for the treatment of glaucoma

Cholesterol regulates TRPV4-dependent signaling in the trabecular meshwork

Polymodal Sensory Transduction in Mouse Corneal Epithelial Cells

Corneal mechanotransduction drives TRPV4-dependent release of the transmitter ATP

The Mechanogated PIEZO1 Channel Regulates Ca 2+ Homeostasis and Formation of Focal Contacts in Human Trabecular Meshwork Cells

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