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Meeting Abstract (5)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (7)

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ARVO Annual Meeting Abstract (5)
Genetics (1)
Retina (1)

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Genetics (2)
Nanotechnology and Regenerative Medicine (2)
Retina (1)

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gene therapy (2)
injections (2)
suidae (2)
anisotropy (1)
blister (1)
disease vectors (1)
electroretinography (1)
eye (1)
histopathology tests (1)
injection site (1)

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Genetics January 2025

Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs

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Peter Kiraly; Joshua Klein; Immanuel P. Seitz; Felix F. Reichel; Tobias Peters; Taras Ardan; Jana Juhasova; Stefan Juhás; Zdenka Ellederova; Yaroslav Nemesh; Ruslan Nyshchuk; Nikolai Klymiuk; Kerstin Nagel-Wolfrum; Ashley R. Winslow; Uwe Wolfrum; Jan Motlik; M. Dominik Fischer
TAGS: disease vectors, gene therapy, injections, safety, spatial vectors, suidae, transgenes, retina, histopathology tests, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):48. https://doi.org/10.1167/iovs.66.1.48

Includes: Supplemental Content

Retina October 2024

Optimizing Subretinal Bleb Formation for Visual Streak Involvement in a Porcine Model for Retinal Gene Therapy

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Immanuel P. Seitz; Tobias Peters; Felix Reichel; Andrea Bähr; Hanna Auch; Jan Motlik; Taras Ardan; Jana Juhasova; Yaroslav Nemesh; Stefan Juhás; Nikolai Klymiuk; Manuel Dominik Fischer
TAGS: blister, eye, gene therapy, injection site, injections, suidae, anisotropy
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):41. https://doi.org/10.1167/iovs.65.12.41

ARVO Annual Meeting Abstract June 2024

Engineered AAV capsid variants allow efficient in vivo and ex vivo gene transfer into the porcine retina

Knut Stieger; Maria Weller; Katerina Nemesh; Sabrina Babutzka; Yaroslav Nemesh; Ruslan Nyshchuk; Brigitte Müller; Taras Ardan; Stefan Juhas; Jana Juhasova; Ivona Valenkova; Jana Čízková; Zdenka Ellederova; Jan Motlik; Lyubomyr Lytvynchuk; Stylianos Michalakis

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2217.

ARVO Annual Meeting Abstract June 2024

A new subretinal gene therapy for USH1C is well tolerated in wild type pigs

Peter Kiraly; Matthias Mai; Tobias Peters; Immanuel P Seitz; Taras Ardan; Zdenka Ellederova; Yaroslav Nemesh; Ruslan Nyshchuk; Nikolai Klymiuk; Ashley Winslow; Joshua Klein; Kerstin Nagel-Wolfrum; Uwe Wolfrum; Jan Motlik; M Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5341.

ARVO Annual Meeting Abstract June 2023

Optimizing Subretinal Bleb Formation in a Porcine Model for Retinal Gene Therapy

Immanuel Philipp Seitz; Tobias Peters; Bähr Andrea; Hannah Auch; Motlik Jan; Taras Ardan; Yaroslav Nemesh; Stefan Juhas; Nikolai Klymiuk; Dominik M Fischer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):778.

ARVO Annual Meeting Abstract June 2022

Quantification of the porcine Abca4 V1965X Prime Edit gene correction

Tobias Wimmer; Hannah Sawinski; Urban Anne; Jan Motlik; Knut Stieger

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):85 – A0058.

ARVO Annual Meeting Abstract July 2018

Safety and feasibility of new nanofiber subretinal delivery system with injector for RPE cell transplantation.

Igor Kozak; Zbynek Stranak; Stepan Popelka; Taras Ardan; David Rais; Jana Cizkova; Sonali Rohiwal; Jan Motlik

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5670.

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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