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Cornea September 2012

Ethyl Pyruvate Ameliorates Endotoxin-Induced Corneal Inflammation

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Divya Gupta; Yiqin Du; Jordan Piluek; Adam M. Jakub; Kristine Ann Buela; Akshar Abbott; Joel S. Schuman; Nirmala SundarRaj
TAGS: anti-inflammatory agents, cornea, keratitis, mice, pyruvates, prednisolone, endotoxins, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6589-6599. https://doi.org/10.1167/iovs.11-9266

Cornea March 2012

Optical Coherence Tomography as a Rapid, Accurate, Noncontact Method of Visualizing the Palisades of Vogt

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Kira L. Lathrop; Divya Gupta; Larry Kagemann; Joel S. Schuman; Nirmala SundarRaj
TAGS: cornea, diagnostic imaging, optical coherence tomography, reconstructive surgical procedures, body tissue
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1381-1387. https://doi.org/10.1167/iovs.11-8524

Includes: Multimedia, Supplemental Content

Cornea November 2011

FGF-2– and TGF-β1–Induced Downregulation of Lumican and Keratocan in Activated Corneal Keratocytes by JNK Signaling Pathway

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Jian Chen; Julie Wong-Chong; Nirmala SundarRaj
TAGS: cornea, down-regulation, fibroblast growth factor 2, keratocytes, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2011; 52(12):8957-8964. https://doi.org/10.1167/iovs.11-8078

Cornea July 2011

Initial In Vitro Investigation of the Human Immune Response to Corneal Cells from Genetically Engineered Pigs

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Hidetaka Hara; Naoko Koike; Cassandra Long; Jordan Piluek; Danny S. Roh; Nirmala SundarRaj; James L. Funderburgh; Yoshiaki Mizuguchi; Kumiko Isse; Carol J. Phelps; Suyapa F. Ball; David L. Ayares; David K. C. Cooper
TAGS: cornea, genetic engineering, immune response, suidae, chronic exertional compartment syndrome
Invest. Ophthalmol. Vis. Sci.. 2011; 52(8):5278-5286. https://doi.org/10.1167/iovs.10-6947

ARVO Annual Meeting Abstract April 2011

Rac GTPase Differentially Regulates TGF-bete1 and PDGF-BB-mediated Regulation of alpha-Smooth Muscle Actin Expression in Activated Corneal Keratocytes

Nirmala Sundarraj; Julie Wong Chong; Rajesh Bhattacharjee; Jian Chen

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2526.

Cornea June 2010

Responses of Cultured Human Keratocytes and Myofibroblasts to Ethyl Pyruvate: A Microarray Analysis of Gene Expression

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Stephen A. K. Harvey; Emily Guerriero; Nahthai Charukamnoetkanok; Jordan Piluek; Joel S. Schuman; Nirmala SundarRaj
TAGS: genes, keratocytes, myofibroblasts, pyruvates, gene expression, cornea, phenotype
Invest. Ophthalmol. Vis. Sci.. 2010; 51(6):2917-2927. https://doi.org/10.1167/iovs.09-4498

ARVO Annual Meeting Abstract April 2010

Ethyl Pyruvate's Effects on the TGF-B1-Induced Expression of -Smooth Muscle Actin and Fibronectin in Human Tenon's Capsule and Trabecular Meshwork Cells

A. B. Abbott; J. Chen; T. Stubbs; J. Schuman; N. SundarRaj

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3201.

ARVO Annual Meeting Abstract April 2010

Downstream Effects of Rac Signaling During TGF-β1 and FGF-2-Induced Activation of Corneal Keratocytes

N. Sundarraj; J. Wong Chong; J. Chen

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):6234.

Cornea August 2009

Rho-Mediated Regulation of TGF-β1– and FGF-2–Induced Activation of Corneal Stromal Keratocytes

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Jian Chen; Emily Guerriero; Yoshikazu Sado; Nirmala SundarRaj
TAGS: cornea, fibroblast growth factor 2, keratocytes, regulation, signal transduction, collagen
Invest. Ophthalmol. Vis. Sci.. 2009; 50(8):3662-3670. https://doi.org/10.1167/iovs.08-3276

ARVO Annual Meeting Abstract April 2009

Signaling Pathways in Downregulation of Keratan Sulfate Proteoglycans in Activated Corneal Keratocytes

N. Sundarraj; J. Chen; E. Guerriero; P. Kinchington

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4541.

ARVO Annual Meeting Abstract May 2008

The Effect of Ethyl Pyruvate on the Corneal Wound Healing Phenotype

W. J. Piluek; S. A. Harvey; R. Eberwine; N. Charukamnoetkanok; J. S. Schuman; N. SundarRaj

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2967.

ARVO Annual Meeting Abstract May 2008

Rho Family GTPases in Regulation of the Loss in Alpha 3(IV) Collagen Expression in Activated Corneal Keratocytes

N. Sundarraj; E. Guerriero; J. Chen; R. Eberwine; P. Kinchington

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4037.

ARVO Annual Meeting Abstract May 2008

Cell Cycle Progression in Corneal Epithelium, via Rho/ROCK Signaling, Functions via Cytoskeletal Rearrangement

R. A. Eberwine; E. R. Guerriero; J. Chen; N. Sundarraj

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4292.

Cornea January 2008

Rho/ROCK Signaling in Regulation of Corneal Epithelial Cell Cycle Progression

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Jian Chen; Emily Guerriero; Kira Lathrop; Nirmala SundarRaj
TAGS: cdk2 protein, human, cdkn1b gene, cell cycle, corneal epithelial cells, cyclin d1, cyclin-dependent kinase 4, cyclins, proteins, regulation, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2008; 49(1):175-183. https://doi.org/10.1167/iovs.07-0488

Cornea November 2007

Secretion and Organization of a Cornea-like Tissue In Vitro by Stem Cells from Human Corneal Stroma

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Yiqin Du; Nirmala SundarRaj; Martha L. Funderburgh; Stephen A. Harvey; David E. Birk; James L. Funderburgh
TAGS: bodily secretions, body tissue, cornea, corneal stroma, fibrin, gel, keratan sulfate, keratocytes, stem cells, genes
Invest. Ophthalmol. Vis. Sci.. 2007; 48(11):5038-5045. https://doi.org/10.1167/iovs.07-0587

Cornea November 2007

Compositional Differences between Infant and Adult Human Corneal Basement Membranes

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Andrea Kabosova; Dimitri T. Azar; Gregory A. Bannikov; Kevin P. Campbell; Madeleine Durbeej; Reza F. Ghohestani; Jonathan C. R. Jones; M. Cristina Kenney; Manuel Koch; Yoshifumi Ninomiya; Bruce L. Patton; Mats Paulsson; Yoshikazu Sado; E. Helene Sage; Takako Sasaki; Lydia M. Sorokin; Marie-France Steiner-Champliaud; Tung-Tien Sun; Nirmala SundarRaj; Rupert Timpl; Ismo Virtanen; Alexander V. Ljubimov
TAGS: adult, basement membrane, cornea, infant, laminin, collagen type iv, epithelium, evidence-based medicine, antibodies
Invest. Ophthalmol. Vis. Sci.. 2007; 48(11):4989-4999. https://doi.org/10.1167/iovs.07-0654

ARVO Annual Meeting Abstract May 2007

MAPK Pathways in the Regulation of b-FGF and TGF-beta1 Induced Keratocyte Activation in vitro

N. Sundarraj; E. Guerriero; J. Chen

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):2751.

ARVO Annual Meeting Abstract May 2007

Bevacizumab Binding to Human Sclera Post Topical Application

J. Y. Yu; M. Y. Kahook; J. S. Schuman; N. SundarRaj; E. Guerriero; R. J. Noecker

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):4815.

Cornea February 2007

Loss of Alpha3(IV) Collagen Expression Associated with Corneal Keratocyte Activation

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Emily Guerriero; Jian Chen; Yoshikazu Sado; Rajiv R. Mohan; Steven E. Wilson; James L. Funderburgh; Nirmala SundarRaj
TAGS: collagen, cornea, keratocytes, stromal cells, oryctolagus cuniculus, fibroblast growth factor 2, rna, messenger, insulin
Invest. Ophthalmol. Vis. Sci.. 2007; 48(2):627-635. https://doi.org/10.1167/iovs.06-0635

ARVO Annual Meeting Abstract May 2006

Bevacizumab Binding to Human Sclera Post Topical Application

S. Beaton; J.Y. Yu; M.Y. Kahook; E. Guerriero; N. SundarRaj; J.S. Schuman; R.J. Noecker

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):46.

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Ethyl Pyruvate Ameliorates Endotoxin-Induced Corneal Inflammation

Optical Coherence Tomography as a Rapid, Accurate, Noncontact Method of Visualizing the Palisades of Vogt

FGF-2– and TGF-β1–Induced Downregulation of Lumican and Keratocan in Activated Corneal Keratocytes by JNK Signaling Pathway

Initial In Vitro Investigation of the Human Immune Response to Corneal Cells from Genetically Engineered Pigs

Rac GTPase Differentially Regulates TGF-bete1 and PDGF-BB-mediated Regulation of alpha-Smooth Muscle Actin Expression in Activated Corneal Keratocytes

Responses of Cultured Human Keratocytes and Myofibroblasts to Ethyl Pyruvate: A Microarray Analysis of Gene Expression

Ethyl Pyruvate's Effects on the TGF-B1-Induced Expression of -Smooth Muscle Actin and Fibronectin in Human Tenon's Capsule and Trabecular Meshwork Cells

Downstream Effects of Rac Signaling During TGF-β1 and FGF-2-Induced Activation of Corneal Keratocytes

Rho-Mediated Regulation of TGF-β1– and FGF-2–Induced Activation of Corneal Stromal Keratocytes

Signaling Pathways in Downregulation of Keratan Sulfate Proteoglycans in Activated Corneal Keratocytes

The Effect of Ethyl Pyruvate on the Corneal Wound Healing Phenotype

Rho Family GTPases in Regulation of the Loss in Alpha 3(IV) Collagen Expression in Activated Corneal Keratocytes

Cell Cycle Progression in Corneal Epithelium, via Rho/ROCK Signaling, Functions via Cytoskeletal Rearrangement

Rho/ROCK Signaling in Regulation of Corneal Epithelial Cell Cycle Progression

Secretion and Organization of a Cornea-like Tissue In Vitro by Stem Cells from Human Corneal Stroma

Compositional Differences between Infant and Adult Human Corneal Basement Membranes

MAPK Pathways in the Regulation of b-FGF and TGF-beta1 Induced Keratocyte Activation in vitro

Bevacizumab Binding to Human Sclera Post Topical Application

Loss of Alpha3(IV) Collagen Expression Associated with Corneal Keratocyte Activation

Bevacizumab Binding to Human Sclera Post Topical Application

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