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Immunology and Microbiology February 2023

The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis

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Abdulraouf Ramadan; Zhiyi Cao; Mihaela Gadjeva; Tanweer S. Zaidi; Vijay A. Rathinam; Noorjahan Panjwani
TAGS: inflammasomes, keratitis, nlr family, pyrin domain-containing 3 protein, cornea, pseudomonas, mice, infections
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):11. https://doi.org/10.1167/iovs.64.2.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Galectin-3 modulates monocyte infiltration in the injured cornea by inducing sialyl Lewis X expression

Dina Abusamra; Marina Anastasiou; Noorjahan A Panjwani; Pilar Alcaide; Pablo Argueso

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):419.

ARVO Annual Meeting Abstract June 2022

Targeting Galectin-8 to reduce the severity of Pseudomonas keratitis in a mouse Model

Zhiyi Cao; Mujtaba Hassan; Ulf Nilsson; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1675 – A0505.

ARVO Annual Meeting Abstract June 2021

Galectin 8 impairs TLR4 signaling and dampens innate immune response to P. aeruginosa infection in mouse corneas

Noorjahan A Panjwani; Zhiyi Cao; Abdulraouf Ramadan

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):888.

ARVO Annual Meeting Abstract June 2021

Galectin-3 Inhibition by a Small-Molecule Inhibitor Downregulates Fibrosis-Related Genes and Signaling Pathways in a Mouse Model of Corneal Fibrosis

Zhiyi Cao; Abdulraouf Ramadan; Fredrik Zetterberg; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):700.

ARVO Annual Meeting Abstract June 2020

Impact of galectin-3 inhibition on corneal transcriptome - downregulation of fibrosis-related genes

Zhiyi Cao; Abdulraouf Ramadan; Albert Tai; Fredrik Zetterberg; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4079.

ARVO Annual Meeting Abstract July 2018

Activation of NLRP3 pathway is required for clearance P. aeruginosa infection in C57BL/6 mouse corneas

Noorjahan A Panjwani; Zhiyi Cao; Vijay Rathinam; Mihaela G Gadjeva; Gerald Pier; Tanweer Zaidi; Abdulraouf Ramadan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1546.

ARVO Annual Meeting Abstract July 2018

Treatment with a highly selective Galectin-3 Inhibitor, GAL-200-10, reduces both pathological corneal neovascularization and fibrosis

Zhiyi Cao; Wei-Sheng Chen; Hakon Leffer; Ulf Nilsson; Hans Schambye; anders pedersen; Fredrik Zetterberg; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3332.

ARVO Annual Meeting Abstract July 2018

Targeting of Dynamin, an Essential Regulator of Endocytosis, Protects the Ocular Surface against Oxidative Stress

Andrew Webster; Shravan K Chintala; Joseph Barr; Noorjahan A Panjwani; Pablo Argueso; Shinwu Jeong; M Elizabeth Fini

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3855.

ARVO Annual Meeting Abstract June 2017

Galectin-3 Inhibition by A Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

Noorjahan A Panjwani; Zhiyi Cao; Wei-Sheng Chen; Hakon leffler; Ulf J Nilsson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):996.

ARVO Annual Meeting Abstract June 2017

Galectin-8-Induced Angiogenesis Is Independent of VEGF-A But Dependent on Integrins

Wei-Sheng Chen; Zhiyi Cao; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):998.

Cornea January 2017

Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

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Wei-Sheng Chen*; Zhiyi Cao; Hakon Leffler; Ulf J. Nilsson; Noorjahan Panjwani
TAGS: cornea, corneal neovascularization, fibrosis, galectin 3, angiogenesis, mice, small molecule
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):9-20. https://doi.org/10.1167/iovs.16-20009

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Galectin-1 ameliorates dry eye disease

Paula Kataguiri; Wei-Sheng Chen; Zhiyi Cao; Victor Sendra; Pedram Hamrah; Driss Zoukhri; Kenneth Kenyon; M. Elizabeth Fini; Shinwu Jeong; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):425.

ARVO Annual Meeting Abstract September 2016

Pathological lymphangiogenesis is regulated by galectin-8-dependent crosstalk among VEGF-C, podoplanin and integrin pathways

Wei-Sheng Chen; Zhiyi Cao; Satoshi Sugaya; Maria Jose Lopez; Victor Sendra; Nora V Laver; Pedram Hamrah; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

Verteporfin Inhibits YAP Activation in Trabecular Meshwork Cells without Light Stimulation: Implication for Glaucoma Treatment

Wei-Sheng Chen; Zhiyi Cao; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3284.

ARVO Annual Meeting Abstract June 2015

Clusterin (CLU) Prevents Ocular Surface (OCS) Barrier Damage by an All-or-None Mechanism in a Preclinical Mouse Model of Dry Eye

Shinwu Jeong; Aditi Bauskar; Wendy J Mack; Jerome Mauris; Pablo Argueso; Noorjahan A Panjwani; Stephen C Pflugfelder; M Elizabeth Fini

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):345.

ARVO Annual Meeting Abstract June 2015

Comparison of galectin expression signature in rejected and accepted murine corneal allografts

Satoshi Sugaya; Wei-Sheng Chen; Zhiyi Cao; Kenneth Kenyon; Takefumi Yamaguchi; Masahiro Omoto; Pedram Hamrah; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4029.

ARVO Annual Meeting Abstract June 2015

Pathological lymphangiogenesis is regulated by galectin-8-dependent crosstalk among VEGF-C, podoplanin and integrin pathways

Noorjahan A Panjwani; Wei-Sheng Chen; Zhiyi Cao; Satoshi Sugaya; Hakon Leffler; Ulf J Nilsson; Lijun Xia

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4502.

Cornea January 2015

Fingerprinting of Galectins in Normal, P. aeruginosa –Infected, and Chemically Burned Mouse Corneas

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Wei-Sheng Chen; Zhiyi Cao; Laetitia Truong; Satoshi Sugaya; Noorjahan Panjwani
TAGS: burns, cornea, mice, western blotting, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2015; 56(1):515-525. https://doi.org/10.1167/iovs.14-15338

ARVO Annual Meeting Abstract April 2014

IL-17A-Mediated Protection against Acanthamoeba Keratitis

Amol Suryawanshi; Zhiyi Cao; James Sampson; Noorjahan A Panjwani

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1689.

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The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis

Galectin-3 modulates monocyte infiltration in the injured cornea by inducing sialyl Lewis X expression

Targeting Galectin-8 to reduce the severity of Pseudomonas keratitis in a mouse Model

Galectin 8 impairs TLR4 signaling and dampens innate immune response to P. aeruginosa infection in mouse corneas

Galectin-3 Inhibition by a Small-Molecule Inhibitor Downregulates Fibrosis-Related Genes and Signaling Pathways in a Mouse Model of Corneal Fibrosis

Impact of galectin-3 inhibition on corneal transcriptome - downregulation of fibrosis-related genes

Activation of NLRP3 pathway is required for clearance P. aeruginosa infection in C57BL/6 mouse corneas

Treatment with a highly selective Galectin-3 Inhibitor, GAL-200-10, reduces both pathological corneal neovascularization and fibrosis

Targeting of Dynamin, an Essential Regulator of Endocytosis, Protects the Ocular Surface against Oxidative Stress

Galectin-3 Inhibition by A Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

Galectin-8-Induced Angiogenesis Is Independent of VEGF-A But Dependent on Integrins

Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

Galectin-1 ameliorates dry eye disease

Pathological lymphangiogenesis is regulated by galectin-8-dependent crosstalk among VEGF-C, podoplanin and integrin pathways

Verteporfin Inhibits YAP Activation in Trabecular Meshwork Cells without Light Stimulation: Implication for Glaucoma Treatment

Clusterin (CLU) Prevents Ocular Surface (OCS) Barrier Damage by an All-or-None Mechanism in a Preclinical Mouse Model of Dry Eye

Comparison of galectin expression signature in rejected and accepted murine corneal allografts

Pathological lymphangiogenesis is regulated by galectin-8-dependent crosstalk among VEGF-C, podoplanin and integrin pathways

Fingerprinting of Galectins in Normal, P. aeruginosa –Infected, and Chemically Burned Mouse Corneas

IL-17A-Mediated Protection against Acanthamoeba Keratitis

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