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Genetics August 2017

Choroidal Vasculature in Bietti Crystalline Dystrophy With CYP4V2 Mutations and in Retinitis Pigmentosa With EYS Mutations

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Takako Hirashima; Manabu Miyata; Kenji Ishihara; Tomoko Hasegawa; Masako Sugahara; Ken Ogino; Munemitsu Yoshikawa; Masayuki Hata; Yoshimasa Kuroda; Yuki Muraoka; Sotaro Ooto; Nagahisa Yoshimura
TAGS: crystal structure, mutation, retinitis pigmentosa, vasculature
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):3871-3878. doi: https://doi.org/10.1167/iovs.17-21515

Includes: Supplemental Content

Retina July 2017

Posterior Staphylomas in Pathologic Myopia Imaged by Widefield Optical Coherence Tomography

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Kosei Shinohara; Noriaki Shimada; Muka Moriyama; Takeshi Yoshida; Jost B. Jonas; Nagahisa Yoshimura; Kyoko Ohno-Matsui
TAGS: 3d mri, myopic macular degeneration, optical coherence tomography, staphyloma, eye, sclera
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3750-3758. doi: https://doi.org/10.1167/iovs.17-22319

ARVO Annual Meeting Abstract June 2017

Genome-wide association study identifies a new genetic locus at 2q36.3 for polypoidal choroidal vasculopathy in East Asians: The GAMA consortium

Tien Yin Wong; Masayuki Yasuda; Qiao Fan; Chui Ming Gemmy Cheung; Masato Akiyama; Chiea Chuen Khor; Chi Pui Pang; Kyu Hyung Park; Nagahisa Yoshimura; Ching-Yu Cheng

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1228. doi:

Glaucoma May 2017

Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects

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Munemitsu Yoshikawa; Hideo Nakanishi; Kenji Yamashiro; Masahiro Miyake; Tadamichi Akagi; Norimoto Gotoh; Hanako O. Ikeda; Kenji Suda; Hiroshi Yamada; Tomoko Hasegawa; Yuto Iida; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; for the Nagahama Study Group
TAGS: genes, glaucoma, retinal nerve fiber layer, scotoma, visual field defects, single nucleotide polymorphism, open-angle glaucoma, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2510-2519. doi: https://doi.org/10.1167/iovs.16-20797

Includes: Supplemental Content

Retina January 2017

Intraocular Vascular Endothelial Growth Factor Levels in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration

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Masayuki Hata; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Hiroshi Tamura; Manabu Miyata; Naoko Ueda-Arakawa; Ayako Takahashi; Akitaka Tsujikawa; Nagahisa Yoshimura
TAGS: exudative age-related macular degeneration, vascular endothelial growth factor a, mass or substance concentration per volume
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):292-298. doi: https://doi.org/10.1167/iovs.16-20967

ARVO Annual Meeting Abstract September 2016

Shared and distinct genetic variation contributes to risk of polypoidal choroidal vasculopathy and neovascular age-related macular degeneration in East Asians: The GAMA consortium

Tien Yin Wong; Qiao Fan; Gemmy Cheung; Chiea Chuen Khor; Kyu Hyung Park; Li Jia Chen; Nagahisa Yoshimura; Ching-Yu Cheng

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Evaluation of retinal blood flow before and after topical tafluprost treatment in glaucoma patients using adaptive optics scanning laser ophthalmoscopy

Yuto Iida; Tadamichi Akagi; Hideo Nakanishi; Hanako Ikeda; Satoshi Morooka; Kenji Suda; Tomoko Hasegawa; Hiroshi Yamada; Munemitsu Yoshikawa; Akihito Uji; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2995. doi:

ARVO Annual Meeting Abstract September 2016

Identification of Anti-Hexokinase-1 Antibody in the Sera from Patients with Diabetic Macular Edema

Tatsuya Yoshitake; Tomoaki Murakami; Kiyoshi Suzuma; Shin Yoshitake; Akihito Uji; Masahiro Fujimoto; Yuko Miwa; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3251. doi:

ARVO Annual Meeting Abstract September 2016

Comparison of Retinal Vascular Imaging between Optical Coherence Tomography Angiography and En-Face Optical Coherence Tomography in Diabetic Retinopathy

Yuko Miwa; Tomoaki Murakami; Kiyoshi Suzuma; Akihito Uji; Shin Yoshitake; Masahiro Fujimoto; Tatsuya Yoshitake; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5485. doi:

Glaucoma August 2016

In Vivo Identification of the Posttrabecular Aqueous Outflow Pathway Using Swept-Source Optical Coherence Tomography

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Akihito Uji; Yuki Muraoka; Nagahisa Yoshimura
TAGS: diagnostic imaging, optical coherence tomography, sclera, face
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4162-4169. doi: https://doi.org/10.1167/iovs.16-19869

Includes: Multimedia, Supplemental Content

Glaucoma June 2016

Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer Thickness

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Hideo Nakanishi; Tadamichi Akagi; Kenji Suda; Tomoko Hasegawa; Hiroshi Yamada; Satoshi Yokota; Munemitsu Yoshikawa; Yuto Iida; Hanako Ohashi Ikeda; Satoshi Morooka; Kenji Ishihara; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3203-3210. doi: https://doi.org/10.1167/iovs.15-18798

Includes: Supplemental Content

Retina April 2016

Characterization of Inner Retinal Spots With Inverted Reflectivity on En Face Optical Coherence Tomography in Diabetic Retinopathy

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Rina Yoza; Tomoaki Murakami; Akihito Uji; Kiyoshi Suzuma; Shin Yoshitake; Yoko Dodo; Rima Ghashut; Masahiro Fujimoto; Yuko Miwa; Nagahisa Yoshimura
TAGS: diabetic retinopathy, exanthema, face, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1862-1870. doi: https://doi.org/10.1167/iovs.16-19171

Glaucoma April 2016

Differences in Relationship Between Macular Inner Retinal Layer Thickness and Retinal Sensitivity in Eyes With Early and Progressed Glaucoma

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Makoto Araie; Hiroshi Murata; Aiko Iwase; Masanori Hangai; Kazuhisa Sugiyama; Nagahisa Yoshimura
TAGS: eye, glaucoma, open-angle glaucoma
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1588-1594. doi: https://doi.org/10.1167/iovs.15-18131

Articles March 2016

Efficacy of Column Scatter Plots for Presenting Retinitis Pigmentosa Phenotypes in a Japanese Cohort

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Ken Ogino; Akio Oishi; Maho Oishi; Norimoto Gotoh; Satoshi Morooka; Masako Sugahara; Tomoko Hasegawa; Manabu Miyata; Nagahisa Yoshimura
TAGS: cohort studies, electroretinography, genes, japanese, mutation, phenotype, retinitis pigmentosa, visual acuity, visual fields, cataract
Trans. Vis. Sci. Tech.. 2016; 5(2):4. doi: https://doi.org/10.1167/tvst.5.2.4

Glaucoma December 2015

Altered Transport Velocity of Axonal Mitochondria in Retinal Ganglion Cells After Laser-Induced Axonal Injury In Vitro

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Satoshi Yokota; Yuji Takihara; Shogo Arimura; Seiji Miyake; Yoshihiro Takamura; Nagahisa Yoshimura; Masaru Inatani
TAGS: lasers, mitochondria, mitochondrial transport, velocity, wounds and injuries, retinal ganglion cells, biological transport
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8019-8025. doi: https://doi.org/10.1167/iovs.15-17876

Includes: Multimedia, Supplemental Content

Retina October 2015

Foveal Photoreceptor Deformation as a Significant Predictor of Postoperative Visual Outcome in Idiopathic Epiretinal Membrane Surgery

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Yoshikatsu Hosoda; Sotaro Ooto; Masanori Hangai; Akio Oishi; Nagahisa Yoshimura
TAGS: epiretinal membrane, photoreceptors, postoperative care, preoperative care, surgical procedures, operative, surgery specialty, eye
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6387-6393. doi: https://doi.org/10.1167/iovs.15-16679

Glaucoma August 2015

Diagnosis of Early-Stage Glaucoma by Grid-Wise Macular Inner Retinal Layer Thickness Measurement and Effect of Compensation of Disc-Fovea Inclination

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Chihiro Mayama; Hitomi Saito; Hiroyo Hirasawa; Atsuo Tomidokoro; Makoto Araie; Aiko Iwase; Shinji Ohkubo; Kazuhisa Sugiyama; Masanori Hangai; Nagahisa Yoshimura
TAGS: fovea centralis, glaucoma, specificity of diagnostic test, eye
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5681-5690. doi: https://doi.org/10.1167/iovs.15-17208

Glaucoma August 2015

Comparison of Longitudinal Changes in Functional and Structural Measures for Evaluating Progression of Glaucomatous Optic Neuropathy

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Kenji Suda; Masanori Hangai; Tadamichi Akagi; Hisashi Noma; Yugo Kimura; Tomoko Hasegawa; Hiroshi Yamada; Munemitsu Yoshikawa; Hideo Nakanishi; Hanako Ohashi Ikeda; Nagahisa Yoshimura
TAGS: glaucoma, optic nerve disorders, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5477-5484. doi: https://doi.org/10.1167/iovs.15-16704

Includes: Supplemental Content

Retina August 2015

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

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Masahiro Miyake; Kenji Yamashiro; Hiroshi Tamura; Kyoko Kumagai; Masaaki Saito; Masako Sugahara-Kuroda; Munemitsu Yoshikawa; Maho Oishi; Yumiko Akagi-Kurashige; Isao Nakata; Hideo Nakanishi; Norimoto Gotoh; Akio Oishi; Fumihiko Matsuda; Ryo Yamada; Chiea-Chuen Khor; Yasuo Kurimoto; Tetsuju Sekiryu; Akitaka Tsujikawa; Nagahisa Yoshimura
TAGS: age-related macular degeneration, eye, genes, genetics, incidence, genetic risk, cohort studies, single nucleotide polymorphism, cultural formulation interview, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5353-5361. doi: https://doi.org/10.1167/iovs.14-16020

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Suppression of Drusen-like Deposits by a Novel VCP modulator in CCR2 Deficient Mice

Yuki Muraoka; Hanako Ohashi Ikeda; Yuto Iida; Masayuki Hata; tomoko hasegawa; Munemitsu Yoshikawa; Akira Kakizuka; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2272. doi:

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Choroidal Vasculature in Bietti Crystalline Dystrophy With CYP4V2 Mutations and in Retinitis Pigmentosa With EYS Mutations

Posterior Staphylomas in Pathologic Myopia Imaged by Widefield Optical Coherence Tomography

Genome-wide association study identifies a new genetic locus at 2q36.3 for polypoidal choroidal vasculopathy in East Asians: The GAMA consortium

Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects

Intraocular Vascular Endothelial Growth Factor Levels in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration

Shared and distinct genetic variation contributes to risk of polypoidal choroidal vasculopathy and neovascular age-related macular degeneration in East Asians: The GAMA consortium

Evaluation of retinal blood flow before and after topical tafluprost treatment in glaucoma patients using adaptive optics scanning laser ophthalmoscopy

Identification of Anti-Hexokinase-1 Antibody in the Sera from Patients with Diabetic Macular Edema

Comparison of Retinal Vascular Imaging between Optical Coherence Tomography Angiography and En-Face Optical Coherence Tomography in Diabetic Retinopathy

In Vivo Identification of the Posttrabecular Aqueous Outflow Pathway Using Swept-Source Optical Coherence Tomography

Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer Thickness

Characterization of Inner Retinal Spots With Inverted Reflectivity on En Face Optical Coherence Tomography in Diabetic Retinopathy

Differences in Relationship Between Macular Inner Retinal Layer Thickness and Retinal Sensitivity in Eyes With Early and Progressed Glaucoma

Efficacy of Column Scatter Plots for Presenting Retinitis Pigmentosa Phenotypes in a Japanese Cohort

Altered Transport Velocity of Axonal Mitochondria in Retinal Ganglion Cells After Laser-Induced Axonal Injury In Vitro

Foveal Photoreceptor Deformation as a Significant Predictor of Postoperative Visual Outcome in Idiopathic Epiretinal Membrane Surgery

Diagnosis of Early-Stage Glaucoma by Grid-Wise Macular Inner Retinal Layer Thickness Measurement and Effect of Compensation of Disc-Fovea Inclination

Comparison of Longitudinal Changes in Functional and Structural Measures for Evaluating Progression of Glaucomatous Optic Neuropathy

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

Suppression of Drusen-like Deposits by a Novel VCP modulator in CCR2 Deficient Mice

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