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Cornea October 2016

Reduced Levels of Tear Lacritin Are Associated With Corneal Neuropathy in Patients With the Ocular Component of Sjögren's Syndrome

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Nancy A. McNamara; Shaokui Ge; Salena M. Lee; Alison M. Enghauser; Lindsey Kuehl; Feeling Y.-T. Chen; Marianne Gallup; Robert L. McKown
TAGS: enzyme-linked immunosorbent assay, dry eye syndromes, neurons, sjogren's syndrome, cornea, neuropathy
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5237-5243. doi: 10.1167/iovs.16-19309

ARVO Annual Meeting Abstract September 2016

Reduced Levels of Tear Lacritin are Associated with Corneal Neuropathy in Sjögren’s Syndrome-associated Dry Eye Disease

Robert L McKown; Alison M Enghauser; ShaoKui Ge; Salena Lee; Lindsey Kuehl; Yu Ting Feeling Chen; Marianne Gallup; Nancy A McNamara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5686. doi:

ARVO Annual Meeting Abstract September 2016

Agreement in reading center grading of Isotretinoin(Accutane)-induced meibography changes

Clare Halleran; Scott G Hauswirth; Justin T. Kwan; Milton M Hom; Leslie O'Dell; Allison Moy; Aubrey Schachter; Jennifer Harthan; Meng C Lin; Nancy A McNamara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6219. doi:

ARVO Annual Meeting Abstract June 2015

Immune cell infiltration in Aire KO mice leads to corneal nerve degradation

Nancy A McNamara; Denise Stephens; Jennifer Finley; YuTing Feeling Chen; Sarah Knox

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4808. doi:

ARVO Annual Meeting Abstract June 2015

Lacritin’s active C-terminal peptide, ‘Lacripep’, as an efficient and innovative therapeutic for the treatment of aqueous-deficient dry eye.

Feeling Yu Ting Chen; Denise Stephens; Shaokui Ge; Trinka Vijmasi; Gordon W Laurie; Sarah Knox; Nancy A McNamara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):300. doi:

ARVO Annual Meeting Abstract June 2015

Corneal epithelial changes in Aire -/- mice mediated via the Jak/STAT signaling pathway

Denise Stephens; Feeling Yu Ting Chen; Nancy A McNamara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):305. doi:

Cornea November 2014

Establishing PAX6 as a Biomarker to Detect Early Loss of Ocular Phenotype in Human Patients With Sjögren's Syndrome

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Nancy A. McNamara; Marianne Gallup; Travis C. Porco
TAGS: phenotype, inflammation, epithelium, biological markers, dry eye syndromes, sjogren's syndrome, cornea, mucous membrane, keratinization
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7079-7084. doi: 10.1167/iovs.14-14828

Cornea August 2014

Topical Administration of Lacritin Is a Novel Therapy for Aqueous-Deficient Dry Eye Disease

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Trinka Vijmasi; Feeling Y. T. Chen; Suganthalakshmi Balasubbu; Marianne Gallup; Robert L. McKown; Gordon W. Laurie; Nancy A. McNamara
TAGS: administration, topical, bodily secretions, dry eye syndromes, t-lymphocyte, eye, mice, proteins, personal integrity
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5401-5409. doi: 10.1167/iovs.14-13924

ARVO Annual Meeting Abstract April 2014

Autoimmune regulator (Aire) gene deficient mice, a model of autoimmune-mediated, aqueous-deficient dry eye, exhibit functional alteration of a recently demonstrated, special type of corneal nerves involved in basal tearing, referred to as the dry-sensitive corneal afferents.

Harumitsu Hirata; Thirugnana Vijmasi; Mark I Rosenblatt; Nancy A McNamara

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3666. doi:

ARVO Annual Meeting Abstract April 2014

IFNγ mediates corneal neuropathy in Aire KO mice and alters epithelial progenitor cells

Denise Stephens; Feeling Chen; Sarah Knox; Nancy A McNamara

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5046. doi:

ARVO Annual Meeting Abstract March 2012

Molecular and Functional Characterization of Ocular Progenitors in Autoimmune-mediated Keratinizing Squamous Metaplasia of the Ocular Surface Mucosa

Ying-Ting Chen; Feeling Y. Chen; Trinka Vijmasi; Stanislav Lazarev; Ahmad F. Bahrami; Lisa B. Noble; Marianne Gallup; Nancy A. McNamara

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):571. doi:

ARVO Annual Meeting Abstract March 2012

Essential Role of CD4+ T Cell-Dependent Macrophage Infiltration in the Pathogenesis of Sjögren’s Syndrome-Associated Dry Eye

Nancy A. McNamara; Ying-Ting Chen; Feeling Chen; Ahmad F. Bahrami; Lisa B. Noble; Marianne Gallup; Delu Zhou

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1282. doi:

ARVO Annual Meeting Abstract April 2011

Interleukin-1 Signaling Downregulates Ocular Surface Phenotype Regulator, Pax6, In Keratinizing Squamous Metaplasia Associated With Sjögren’s Syndrome

Ying-Ting Chen; Stanislav Lazarev; Ahmad F. Bahrami; Lisa B. Noble; Delu Zhou; Marianne Gallup; Nancy A. McNamara

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2094. doi:

ARVO Annual Meeting Abstract April 2011

Development of a Microfluidic Immunoassay for Highly Alkaline Human Tear Protein Biomarkers of Sjögren’s Syndrome

Kelly Karns; Nancy A. McNamara; Amy E. Herr

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3748. doi:

Cornea May 2010

Molecular Mechanism of Proinflammatory Cytokine-Mediated Squamous Metaplasia in Human Corneal Epithelial Cells

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Shimin Li; Marianne Gallup; Ying-Ting Chen; Nancy A. McNamara
TAGS: cytokine, cyclic amp-responsive dna-binding protein, metaplasia, proteins, corneal epithelial cells
Invest. Ophthalmol. Vis. Sci.. 2010; 51(5):2466-2475. doi: 10.1167/iovs.09-4677

Cornea August 2009

A Link between Tear Instability and Hyperosmolarity in Dry Eye

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Haixia Liu; Carolyn Begley; Minhua Chen; Arthur Bradley; Joseph Bonanno; Nancy A. McNamara; J. Daniel Nelson; Trefford Simpson
TAGS: dry eye syndromes, osmolar concentration, sodium chloride, sucrose, cornea, sensory perception, hyperosmolality, tear film finding, hyperglycemia hyperosmolar, mosmol
Invest. Ophthalmol. Vis. Sci.. 2009; 50(8):3671-3679. doi: 10.1167/iovs.08-2689

Biochemistry and Molecular Biology January 2008

Small Proline-Rich Protein 1B (SPRR1B) Is a Biomarker for Squamous Metaplasia in Dry Eye Disease

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Shimin Li; Karina Nikulina; Jason DeVoss; Ava J. Wu; Erich C. Strauss; Mark S. Anderson; Nancy A. McNamara
TAGS: cytokine, biological markers, dry eye syndromes, metaplasia, proline, t-lymphocyte, mice, proteins, aire gene
Invest. Ophthalmol. Vis. Sci.. 2008; 49(1):34-41. doi: 10.1167/iovs.07-0685

Cornea November 1999

Measurement of Post–Lens Tear Thickness

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Meng C. Lin; Andrew D. Graham; Kenneth A. Polse; Robert B. Mandell; Nancy A. McNamara
TAGS: lens, crystalline, lens (device), optics, eye
Invest. Ophthalmol. Vis. Sci.. 1999; 40(12):2833-2839. doi:

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Reduced Levels of Tear Lacritin Are Associated With Corneal Neuropathy in Patients With the Ocular Component of Sjögren's Syndrome

Reduced Levels of Tear Lacritin are Associated with Corneal Neuropathy in Sjögren’s Syndrome-associated Dry Eye Disease

Agreement in reading center grading of Isotretinoin(Accutane)-induced meibography changes

Immune cell infiltration in Aire KO mice leads to corneal nerve degradation

Lacritin’s active C-terminal peptide, ‘Lacripep’, as an efficient and innovative therapeutic for the treatment of aqueous-deficient dry eye.

Corneal epithelial changes in Aire -/- mice mediated via the Jak/STAT signaling pathway

Establishing PAX6 as a Biomarker to Detect Early Loss of Ocular Phenotype in Human Patients With Sjögren's Syndrome

Topical Administration of Lacritin Is a Novel Therapy for Aqueous-Deficient Dry Eye Disease

Autoimmune regulator (Aire) gene deficient mice, a model of autoimmune-mediated, aqueous-deficient dry eye, exhibit functional alteration of a recently demonstrated, special type of corneal nerves involved in basal tearing, referred to as the dry-sensitive corneal afferents.

IFNγ mediates corneal neuropathy in Aire KO mice and alters epithelial progenitor cells

Molecular and Functional Characterization of Ocular Progenitors in Autoimmune-mediated Keratinizing Squamous Metaplasia of the Ocular Surface Mucosa

Essential Role of CD4+ T Cell-Dependent Macrophage Infiltration in the Pathogenesis of Sjögren’s Syndrome-Associated Dry Eye

Interleukin-1 Signaling Downregulates Ocular Surface Phenotype Regulator, Pax6, In Keratinizing Squamous Metaplasia Associated With Sjögren’s Syndrome

Development of a Microfluidic Immunoassay for Highly Alkaline Human Tear Protein Biomarkers of Sjögren’s Syndrome

Molecular Mechanism of Proinflammatory Cytokine-Mediated Squamous Metaplasia in Human Corneal Epithelial Cells

A Link between Tear Instability and Hyperosmolarity in Dry Eye

Small Proline-Rich Protein 1B (SPRR1B) Is a Biomarker for Squamous Metaplasia in Dry Eye Disease

Measurement of Post–Lens Tear Thickness

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