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Journal Articles (14)
Meeting Abstract (2)

Journal

Investigative Ophthalmology & Visual Science (15)
Journal of Vision (1)

Article Type

Anatomy and Pathology/Oncology (7)
Biochemistry and Molecular Biology (3)
ARVO Annual Meeting Abstract (2)
Clinical and Epidemiologic Research (1)
Research Article (1)
Retina (1)
Visual Psychophysics and Physiological Optics (1)

Topics

Visual Psychophysics and Physiological Optics (12)
Eye Anatomy and Disorders (11)
Lens (4)
Biochemistry and Molecular Biology (3)
Clinical and Epidemiologic Research (1)
Cornea (1)
Genetics (1)
Glaucoma (1)
Imaging (1)
Pharmacology (1)
Retina (1)
Spatial Vision (1)

Tags

myopia (11)
eye (8)
sclera (8)
tupaiidae (7)
lens (device) (5)
lens, crystalline (5)
collagen (4)
body weight (2)
refractive errors (2)
timp2 protein, human (2)

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Biochemistry and Molecular Biology April 2017

Reduced Scleral TIMP-2 Expression Is Associated With Myopia Development: TIMP-2 Supplementation Stabilizes Scleral Biomarkers of Myopia and Limits Myopia Development

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Hsin-Hua Liu; Megan S. Kenning; Andrew I. Jobling; Neville A. McBrien; Alex Gentle
TAGS: gelatinase a, myopia, sclera, timp2 protein, human, collagen
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):1971-1981. https://doi.org/10.1167/iovs.16-21181

Anatomy and Pathology/Oncology April 2013

Eyes in Various Species Can Shorten to Compensate for Myopic Defocus

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Xiaoying Zhu; Neville A. McBrien; Earl L. Smith, III; David Troilo; Josh Wallman
TAGS: eye, lens (device), lens, crystalline, myopia
Invest. Ophthalmol. Vis. Sci.. 2013; 54(4):2634-2644. https://doi.org/10.1167/iovs.12-10514

Anatomy and Pathology/Oncology August 2012

Muscarinic Antagonist Control of Myopia: Evidence for M 4 and M 1 Receptor-Based Pathways in the Inhibition of Experimentally-Induced Axial Myopia in the Tree Shrew

PDF

Baskar Arumugam; Neville A. McBrien
TAGS: antagonists, myopia, tupaiidae
Invest. Ophthalmol. Vis. Sci.. 2012; 53(9):5827-5837. https://doi.org/10.1167/iovs.12-9943

ARVO Annual Meeting Abstract March 2012

Spiperone Prevents M1 Muscarinic Antagonist Inhibition of Myopia in Tree shrew

Baskar Arumugam; Neville A. McBrien

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3431.

Clinical and Epidemiologic Research March 2012

The Effect of Daily Transient +4 D Positive Lens Wear on the Inhibition of Myopia in the Tree Shrew

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Neville A. McBrien; Baskar Arumugam; Sangeetha Metlapally
TAGS: lens (device), lens, crystalline, myopia, tupaiidae
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1593-1601. https://doi.org/10.1167/iovs.11-7859

ARVO Annual Meeting Abstract April 2011

Replenishment of TIMP-2 Significantly Reduces Scleral Collagen Degradation and Axial Myopia in Tree Shrew

Hsin-Hua Liu; Alex Gentle; Megan S. Kenning; Neville A. McBrien

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6307.

Anatomy and Pathology/Oncology November 2010

The Effect of Pirenzepine on Positive- and Negative-Lens–Induced Refractive Error and Ocular Growth in Chicks

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Sangeetha Metlapally; Neville A. McBrien
TAGS: eye, lens (device), lens, crystalline, pirenzepine, refractive errors, myopia, sclera, hyperopia
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5438-5444. https://doi.org/10.1167/iovs.09-4431

Biochemistry and Molecular Biology June 2010

Inhibition of Matrix Metalloproteinase Activity in the Chick Sclera and Its Effect on Myopia Development

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Hsin-Hua Liu; Alex Gentle; Andrew I. Jobling; Neville A. McBrien
TAGS: catabolism, collagen, matrix metalloproteinases, myopia, sclera, timp2 protein, human, proline
Invest. Ophthalmol. Vis. Sci.. 2010; 51(6):2865-2871. https://doi.org/10.1167/iovs.09-4322

Retina January 2009

Relationship of the Optical Coherence Tomography Signal to Underlying Retinal Histology in the Tree Shrew ( Tupaia belangeri )

PDF

Carla J. Abbott; Neville A. McBrien; Ulrike Grünert; Michael J. Pianta
TAGS: histology, optical coherence tomography, tupaiidae, retina, tupaia
Invest. Ophthalmol. Vis. Sci.. 2009; 50(1):414-423. https://doi.org/10.1167/iovs.07-1197

Research Article March 2008

The effect of positive lens defocus on ocular growth and emmetropization in the tree shrew

PDF

Sangeetha Metlapally; Neville A. McBrien
TAGS: lens (device), lens, crystalline, tupaiidae
Journal of Vision. 2008; 8(3):1. https://doi.org/10.1167/8.3.1

Anatomy and Pathology/Oncology November 2006

Expression of Collagen-Binding Integrin Receptors in the Mammalian Sclera and Their Regulation during the Development of Myopia

PDF

Neville A. McBrien; Ravikanth Metlapally; Andrew I. Jobling; Alex Gentle
TAGS: collagen, integrins, myopia, sclera, regulation, mammals, eye
Invest. Ophthalmol. Vis. Sci.. 2006; 47(11):4674-4682. https://doi.org/10.1167/iovs.05-1150

Visual Psychophysics and Physiological Optics August 2006

Altered Visual Sensitivity in Axial High Myopia: A Local Postreceptoral Phenomenon?

PDF

Alexandra Jaworski; Alex Gentle; Andrew J. Zele; Algis J. Vingrys; Neville A. McBrien
TAGS: contrast sensitivity, eye, lens (device), lens, crystalline, luminance, myopia, psychophysics, spatial summation, vitreous body, spatial frequency
Invest. Ophthalmol. Vis. Sci.. 2006; 47(8):3695-3702. https://doi.org/10.1167/iovs.05-1569

Anatomy and Pathology/Oncology March 2004

Pressure-Induced Changes in Axial Eye Length of Chick and Tree Shrew: Significance of Myofibroblasts in the Sclera

PDF

John R. Phillips; Neville A. McBrien
TAGS: eye, myofibroblasts, sclera, tupaiidae, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2004; 45(3):758-763. https://doi.org/10.1167/iovs.03-0732

Anatomy and Pathology/Oncology September 2001

Structural and Ultrastructural Changes to the Sclera in a Mammalian Model of High Myopia

PDF

Neville A. McBrien; Lynn M. Cornell; Alex Gentle
TAGS: collagen, fibril, myopia, sclera, eye, body weight
Invest. Ophthalmol. Vis. Sci.. 2001; 42(10):2179-2187.

Biochemistry and Molecular Biology November 2000

Scleral Remodeling during the Development of and Recovery from Axial Myopia in the Tree Shrew

PDF

Neville A. McBrien; Patrick Lawlor; Alex Gentle
TAGS: myopia, recovery of function, sclera, tupaiidae, eye, sulfate, body weight, body tissue, glycosaminoglycans
Invest. Ophthalmol. Vis. Sci.. 2000; 41(12):3713-3719.

Anatomy and Pathology/Oncology July 2000

Induced Myopia Associated with Increased Scleral Creep in Chick and Tree Shrew Eyes

PDF

John R. Phillips; Mohammad Khalaj; Neville A. McBrien
TAGS: eye, myopia, sclera, tupaiidae
Invest. Ophthalmol. Vis. Sci.. 2000; 41(8):2028-2034.

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