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ARVO Annual Meeting Abstract June 2024

Cell Populations and Gene Expression in Cornea and Limbus Relevant to Nerve Regeneration using Single Cell Transcriptomics

Abhilash Ponnath; Surjyadipta Bhattacharjee; William C Gordon; Nicolas G Bazan; Haydee E P Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):60.

ARVO Annual Meeting Abstract June 2024

Elovanoids sustain retinal pigment epithelial cell survival by suppressing lipid peroxidation

Rasangi Perera; Jorgelina Muriel Calandria; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):191.

ARVO Annual Meeting Abstract June 2024

Elovanoids (ELV-N32 and ELV-N34) promote survival of human RPE cells via CNR2 and GPR120 receptors

Surjyadipta Bhattacharjee; Jorgelina Muriel Calandria; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1332.

ARVO Annual Meeting Abstract June 2024

Lipid mediators suppress inflammasome activation by downregulating NLRP3 and NOD2 in retinal pigment epithelium

Jeff Xiang Ji; Jorgelina Muriel Calandria; Marie-Audrey Ines Kautzmann; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1325.

ARVO Annual Meeting Abstract June 2024

ABC cells a novel cell lineage that recapitulates human retinal pigment epithelium

Jorgelina Muriel Calandria; Marie-Audrey Ines Kautzmann; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1323.

ARVO Annual Meeting Abstract June 2024

Enzymatic perturbations of fatty acids synthesis in Mfrp and Adipor1-associated retinal degenerations

Marie-Audrey Ines Kautzmann; Pranab K Mukherjee; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1321.

ARVO Annual Meeting Abstract June 2024

TXNRD1-TRX modulates ferroptosis in RPE cells via redox signaling

Nicolas G Bazan; Surjyadipta Bhattacharjee; Jorgelina Muriel Calandria

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2186.

ARVO Annual Meeting Abstract June 2024

Spatially Resolved Transcriptomics Reveal Changing Landscape of Survival Molecular Signatures in Age-Related Macular Degeneration

Warner Moore; Surjyadipta Bhattacharjee; Marie-Audrey Ines Kautzmann; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4991.

Retinal Cell Biology November 2023

DHA Shortage Causes the Early Degeneration of Photoreceptors and RPE in Mice With Peroxisomal β-Oxidation Deficiency

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Daniëlle Swinkels; Sai Kocherlakota; Yannick Das; Adriaan D. Dane; Eric J. M. Wever; Frédéric M. Vaz; Nicolas G. Bazan; Paul P. Van Veldhoven; Myriam Baes
TAGS: diet, mice, photoreceptors, tissue degeneration, oxidation, neural retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):10. https://doi.org/10.1167/iovs.64.14.10

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract June 2023

Mass spectrometry molecular imaging of periphery and macula photoreceptors of human retinal degeneration

Marie-Audrey Ines Kautzmann; William C. Gordon; Rasangi M. Perera; Jeff X. Ji; Megan L. Cothern; Nicolas G. Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PB0049.

ARVO Annual Meeting Abstract June 2023

Deletion of membrane-type frizzled-related protein (MFRP) or adiponectin receptor 1 (AdipoR1) results in selective fatty acid synthesis impairments and photoreceptor cell degeneration in mice

Alise Aucoin; Marie-Audrey Kautzmann Guerin; William C Gordon; Jeff Ji; Rasangi Perera; Jasmine Elison; Maria Reinoso; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4866.

ARVO Annual Meeting Abstract June 2023

VLC-PUFA supplementation increases Elovanoid synthesis in a two-compartment Late-Onset Retinal Degeneration-iRPE model

Jeff Xiang Ji; Jorgelina Muriel Calandria; Megan Cothern; Rasangi Perera; Kapil Bharti; Kiyoharu Miyagishima; Ruchi Sharma; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5456.

ARVO Annual Meeting Abstract June 2023

ALPHA-1 ANTITRYPSIN INCREASES EXPRESSION OF PROTEINS INVOLVED IN NPD1 SYNTHESIS OF CELLS EXPOSED TO HIGH GLUCOSE

Juan E Gallo; Luciano Magurno; Valentina De Caso Ward; Romina Mouriño; Nicolas G Bazan; MARÍA CONSTANZA POTILINSKI

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):992.

ARVO Annual Meeting Abstract June 2023

Metformin Attenuates the Hallmarks of Stargardt Disease

Mitra Farnoodian; Francesca Barone; Marisa Boyle; Rishabh Gupta; Luke Matthew Nelson; Devika Abhijit Bose; Bokkyoo Jun; William C Gordon; Khanh V Do; Marie-Audrey Kautzmann Guerin; Tiziana Cogliati; Peter Walter; Laryssa Huryn; Nicolas G Bazan; Brian Patrick Brooks; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):476.

ARVO Annual Meeting Abstract June 2023

Elovanoid N34:6 selectively interacts with cytosolic TXNRD1 to promote cell survival in RPE cells

Jorgelina Muriel Calandria; Surjyadipta Bhattacharjee; Sayantani Kala-Bhattacharjee; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):431.

ARVO Annual Meeting Abstract June 2023

Lack of synergistic neuroprotection and Sirt1 upregulation by Elovanoids (ElVs) and Neuroprotectin D1 (NPD1) against uncompensated oxidative stress in human retinal pigment epithelial cells (RPE).

Pranab k Mukherjee; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2980.

ARVO Annual Meeting Abstract June 2023

Spatial transcriptomics define cell heterogeneity in limbal/corneal epithelial stem/early transit amplifying cells in mice cornea after damage

Abhilash Ponnath; Surjyadipta Bhattacharjee; William C Gordon; Jiucheng He; Nicolas G Bazan; Haydee E P Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3133.

ARVO Annual Meeting Abstract June 2023

Active Biosynthesis of Elovanoids Enhance Cell Viability in Response to Uncompensated Oxidative Stress in a New Human Retinal Pigment Epithelial Cell Model

Rasangi Perera; Megan Cothern; Jeff Xiang Ji; Jorgelina Muriel Calandria; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3894.

ARVO Annual Meeting Abstract June 2023

Elovanoids modulate RAMP and GPCR mediated retinal epithelial cell protection

Gethein Andrew; Jorgelina Muriel Calandria; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4470.

ARVO Annual Meeting Abstract June 2023

Caspase-1 activation and IL-1 secretion are counteracted by elovanoids in retinal cells, engaging NOD2 signaling pathway activation

Marie-Audrey Ines Kautzmann; Aram Asatrian; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4469.

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Cell Populations and Gene Expression in Cornea and Limbus Relevant to Nerve Regeneration using Single Cell Transcriptomics

Elovanoids sustain retinal pigment epithelial cell survival by suppressing lipid peroxidation

Elovanoids (ELV-N32 and ELV-N34) promote survival of human RPE cells via CNR2 and GPR120 receptors

Lipid mediators suppress inflammasome activation by downregulating NLRP3 and NOD2 in retinal pigment epithelium

ABC cells a novel cell lineage that recapitulates human retinal pigment epithelium

Enzymatic perturbations of fatty acids synthesis in Mfrp and Adipor1-associated retinal degenerations

TXNRD1-TRX modulates ferroptosis in RPE cells via redox signaling

Spatially Resolved Transcriptomics Reveal Changing Landscape of Survival Molecular Signatures in Age-Related Macular Degeneration

DHA Shortage Causes the Early Degeneration of Photoreceptors and RPE in Mice With Peroxisomal β-Oxidation Deficiency

Mass spectrometry molecular imaging of periphery and macula photoreceptors of human retinal degeneration

Deletion of membrane-type frizzled-related protein (MFRP) or adiponectin receptor 1 (AdipoR1) results in selective fatty acid synthesis impairments and photoreceptor cell degeneration in mice

VLC-PUFA supplementation increases Elovanoid synthesis in a two-compartment Late-Onset Retinal Degeneration-iRPE model

ALPHA-1 ANTITRYPSIN INCREASES EXPRESSION OF PROTEINS INVOLVED IN NPD1 SYNTHESIS OF CELLS EXPOSED TO HIGH GLUCOSE

Metformin Attenuates the Hallmarks of Stargardt Disease

Elovanoid N34:6 selectively interacts with cytosolic TXNRD1 to promote cell survival in RPE cells

Lack of synergistic neuroprotection and Sirt1 upregulation by Elovanoids (ElVs) and Neuroprotectin D1 (NPD1) against uncompensated oxidative stress in human retinal pigment epithelial cells (RPE).

Spatial transcriptomics define cell heterogeneity in limbal/corneal epithelial stem/early transit amplifying cells in mice cornea after damage

Active Biosynthesis of Elovanoids Enhance Cell Viability in Response to Uncompensated Oxidative Stress in a New Human Retinal Pigment Epithelial Cell Model

Elovanoids modulate RAMP and GPCR mediated retinal epithelial cell protection

Caspase-1 activation and IL-1 secretion are counteracted by elovanoids in retinal cells, engaging NOD2 signaling pathway activation

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