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Anatomy and Pathology/Oncology April 2024

The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group

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Natasha M. van Poppelen; Nathalie Cassoux; Joni A. Turunen; Nicole C. Naus; Robert M. Verdijk; Jolanda Vaarwater; Victoria Cohen; Vasilios P. Papastefanou; Hayyam Kiratli; Svetlana V. Saakyan; Alexander Y. Tsygankov; Iwona Rospond-Kubiak; Hardeep S. Mudhar; Sachin M. Salvi; Jens F. Kiilgaard; Steffen Heegaard; Alexandre P. Moulin; Maria A. Saornil; Ciro Garciá-Alvarez; Maria Fili; Nils A. Eide; Peter Meyer; Tero T. Kivelä; Annelies de Klein; Emine Kilic; Rana'a T. Al-Jamal
TAGS: bap1 gene, ciliary body melanoma, european continental ancestry group, eye, genetic research, intraocular melanoma, medical oncology, neoplasm metastasis, neoplasms, pediatrics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):12. https://doi.org/10.1167/iovs.65.4.12

Anatomy and Pathology/Oncology February 2024

Evaluation of Circulating Tumor DNA as a Liquid Biomarker in Uveal Melanoma

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Daniel P. de Bruyn; Natasha M. van Poppelen; Tom Brands; Susanne C. van den Boom; Ellis Eikenboom; Anja Wagner; Monique M. van Veghel-Plandsoen; Geert Geeven; Berna Beverloo; Caroline M. van Rij; Robert M. Verdijk; Nicole C. Naus; Mette M. Bagger; Jens F. Kiilgaard; Annelies de Klein; Erwin Brosens; Emine Kiliç
TAGS: biological markers, circulating tumor dna, intraocular melanoma, neoplasm metastasis, copy number polymorphism, neoplasms, liquids
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):11. https://doi.org/10.1167/iovs.65.2.11

Includes: Supplemental Content

Anatomy and Pathology/Oncology August 2019

Multi-Modality Analysis Improves Survival Prediction in Enucleated Uveal Melanoma Patients

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Wojtek Drabarek; Serdar Yavuzyigitoglu; Askar Obulkasim; Job van Riet; Kyra N. Smit; Natasha M. van Poppelen; Jolanda Vaarwater; Tom Brands; Bert Eussen; Robert M. Verdijk; Nicole C. Naus; Hanneke W. Mensink; Dion Paridaens; Eric Boersma; Harmen J. G. van de Werken; Emine Kilic; Annelies de Klein; for the Rotterdam Ocular Melanoma Study Group
TAGS: copy number polymorphism, histopathology tests, intraocular melanoma, mutation, neoplasms, single nucleotide polymorphism, bap1 gene, neoplasm metastasis, sf3b1 gene, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3595-3605. https://doi.org/10.1167/iovs.18-24818

Includes: Supplemental Content

Anatomy and Pathology/Oncology July 2019

Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions

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Jolique A. van Ipenburg; Nadine E. de Waard; Nicole C. Naus; Martine J. Jager; Dion Paridaens; Robert M. Verdijk
TAGS: atypical, chemokine receptors, chemokines, conjunctiva, cxcr4 receptors, melanoma, nevus, neoplasm metastasis, immune reconstitution inflammatory syndrome, insulin receptor substrate proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2950-2957. https://doi.org/10.1167/iovs.19-27162

Anatomy and Pathology/Oncology April 2016

Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With BAP1 Mutations

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Serdar Yavuzyigitoglu; Hanneke W. Mensink; Kyra N. Smit; Jolanda Vaarwater; Robert M. Verdijk; Berna Beverloo; Hennie T. Brüggenwirth; Ronald van Marion; Hendrikus J. Dubbink; Dion Paridaens; Nicole C. Naus; Annelies de Klein; Emine Kiliç; for the Rotterdam Ocular Melanoma Study Group (ROMS),
TAGS: bap1 gene, intraocular melanoma, mutation, neoplasm metastasis, neoplasms, polyploidy, ploidies, genes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):2232-2239. https://doi.org/10.1167/iovs.15-18608

Includes: Supplemental Content

Anatomy and Pathology/Oncology September 2014

Prevalence and Implications of TERT Promoter Mutation in Uveal and Conjunctival Melanoma and in Benign and Premalignant Conjunctival Melanocytic Lesions

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Anna E. Koopmans; Kimberley Ober; Hendrikus J. Dubbink; Dion Paridaens; Nicole C. Naus; Stephan Belunek; Bart Krist; Edward Post; Ellen C. Zwarthoff; Annelies de Klein; Robert M. Verdijk
TAGS: conjunctiva, eye melanomas, intraocular melanoma, malignant melanoma of conjunctiva, mutation, precancerous conditions, uvea, prevalence, atypical
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):6024-6030. https://doi.org/10.1167/iovs.14-14901

Anatomy and Pathology/Oncology March 2014

The Prognostic Value of Extraocular Extension in Relation to Monosomy 3 and Gain of Chromosome 8q in Uveal Melanoma

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Jackelien G. M. van Beek; Anna E. Koopmans; Jolanda Vaarwater; Johan J. de Rooi; Dion Paridaens; Nicole C. Naus; Annelies de Klein; Robert M. Verdijk; Emine Kiliç
TAGS: chromosomes, extension, intraocular melanoma, monosomy, neoplasms, neoplasm metastasis, diameter
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1284-1291. https://doi.org/10.1167/iovs.13-13670

Genetics May 2012

Higher Percentage of FISH-Determined Monosomy 3 and 8q Amplification in Uveal Melanoma Cells relate to Poor Patient Prognosis

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Thomas van den Bosch; Jackelien G. M. van Beek; Jolanda Vaarwater; Robert M. Verdijk; Nicole C. Naus; Dion Paridaens; Annelies de Klein; Emine Kiliç
TAGS: amplification, chromosomes, intraocular melanoma, monosomy, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):2668-2674. https://doi.org/10.1167/iovs.11-8697

Anatomy and Pathology/Oncology February 2009

Chromosome 3 Intratumor Heterogeneity in Uveal Melanoma

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Hanneke W. Mensink; Jolanda Vaarwater; Emine Kiliç; Nicole C. Naus; Neeltje Mooy; Gre Luyten; Hennie T. Brüggenwirth; Dion Paridaens; Annelies de Klein
TAGS: chromosomes, human, pair 3, heterogeneity, intraocular melanoma, intratumoral route of administration, monosomy, neoplasms, ulnar-mammary syndrome, body tissue, paraffin
Invest. Ophthalmol. Vis. Sci.. 2009; 50(2):500-504. https://doi.org/10.1167/iovs.08-2279

Biochemistry and Molecular Biology October 2008

Gene Expression Profiling in Uveal Melanoma: Two Regions on 3p Related to Prognosis

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Walter van Gils; Elisabeth M. Lodder; Hanneke W. Mensink; Emine Kiliç; Nicole C. Naus; Hennie T. Brüggenwirth; Wilfred van IJcken; Dion Paridaens; Gregorius P. Luyten; Annelies de Klein
TAGS: chromosomes, gene expression profiling, intraocular melanoma, neoplasms, genes, gene expression, ulnar-mammary syndrome
Invest. Ophthalmol. Vis. Sci.. 2008; 49(10):4254-4262. https://doi.org/10.1167/iovs.08-2033

Includes: Supplemental Content

Anatomy and Pathology/Oncology July 2005

Concurrent Loss of Chromosome Arm 1p and Chromosome 3 Predicts a Decreased Disease-Free Survival in Uveal Melanoma Patients

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Emine Kilic; Nicole C. Naus; Walter van Gils; Caroline C. Klaver; Marjan E. van Til; Michael M. Verbiest; Theo Stijnen; Cornelia M. Mooy; Dion Paridaens; H. Berna Beverloo; Gregorius P. Luyten; Annelies de Klein
TAGS: arm of chromosome, chromosomes, human, pair 3, intraocular melanoma, neoplasms, chromosomes, cytogenetic analysis, fluorescent in situ hybridization, neoplasm metastasis
Invest. Ophthalmol. Vis. Sci.. 2005; 46(7):2253-2257. https://doi.org/10.1167/iovs.04-1460

Clinical and Epidemiologic Research August 2002

Cellular Radiosensitivity of Primary and Metastatic Human Uveal Melanoma Cell Lines

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Gerard J. M. J. van den Aardweg; Nicole C. Naus; Anette C. A. Verhoeven; Annelies de Klein; Gregorius P. M. Luyten
TAGS: cell lines, intraocular melanoma, radiation tolerance, malignant melanoma, cutaneous
Invest. Ophthalmol. Vis. Sci.. 2002; 43(8):2561-2565.

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The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group

Evaluation of Circulating Tumor DNA as a Liquid Biomarker in Uveal Melanoma

Multi-Modality Analysis Improves Survival Prediction in Enucleated Uveal Melanoma Patients

Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions

Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With BAP1 Mutations

Prevalence and Implications of TERT Promoter Mutation in Uveal and Conjunctival Melanoma and in Benign and Premalignant Conjunctival Melanocytic Lesions

The Prognostic Value of Extraocular Extension in Relation to Monosomy 3 and Gain of Chromosome 8q in Uveal Melanoma

Higher Percentage of FISH-Determined Monosomy 3 and 8q Amplification in Uveal Melanoma Cells relate to Poor Patient Prognosis

Chromosome 3 Intratumor Heterogeneity in Uveal Melanoma

Gene Expression Profiling in Uveal Melanoma: Two Regions on 3p Related to Prognosis

Concurrent Loss of Chromosome Arm 1p and Chromosome 3 Predicts a Decreased Disease-Free Survival in Uveal Melanoma Patients

Cellular Radiosensitivity of Primary and Metastatic Human Uveal Melanoma Cell Lines

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