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Journal Articles (10)

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Investigative Ophthalmology & Visual Science (10)

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Anatomy and Pathology/Oncology (7)
Biochemistry and Molecular Biology (1)
Clinical and Epidemiologic Research (1)
Genetics (1)

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Eye Anatomy and Disorders (10)
Oncology (10)
Genetics (8)
Biochemistry and Molecular Biology (1)
Clinical and Epidemiologic Research (1)
External Eye Disease (1)
Immunology and Microbiology (1)

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intraocular melanoma (9)
neoplasms (7)
chromosomes (5)
neoplasm metastasis (5)
monosomy (3)
mutation (3)
atypical (2)
bap1 gene (2)
cell lines (2)
chromosomes, human, pair 3 (2)

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Anatomy and Pathology/Oncology August 2019

Multi-Modality Analysis Improves Survival Prediction in Enucleated Uveal Melanoma Patients

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Wojtek Drabarek; Serdar Yavuzyigitoglu; Askar Obulkasim; Job van Riet; Kyra N. Smit; Natasha M. van Poppelen; Jolanda Vaarwater; Tom Brands; Bert Eussen; Robert M. Verdijk; Nicole C. Naus; Hanneke W. Mensink; Dion Paridaens; Eric Boersma; Harmen J. G. van de Werken; Emine Kilic; Annelies de Klein; for the Rotterdam Ocular Melanoma Study Group
TAGS: copy number polymorphism, histopathology tests, intraocular melanoma, mutation, neoplasms, single nucleotide polymorphism, bap1 gene, neoplasm metastasis, sf3b1 gene, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3595-3605. doi: 10.1167/iovs.18-24818

Includes: Supplemental Content

Anatomy and Pathology/Oncology July 2019

Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions

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Jolique A. van Ipenburg; Nadine E. de Waard; Nicole C. Naus; Martine J. Jager; Dion Paridaens; Robert M. Verdijk
TAGS: atypical, chemokine receptors, chemokines, conjunctiva, cxcr4 receptors, melanoma, nevus, neoplasm metastasis, immune reconstitution inflammatory syndrome, insulin receptor substrate proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2950-2957. doi: 10.1167/iovs.19-27162

Anatomy and Pathology/Oncology April 2016

Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With BAP1 Mutations

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Serdar Yavuzyigitoglu; Hanneke W. Mensink; Kyra N. Smit; Jolanda Vaarwater; Robert M. Verdijk; Berna Beverloo; Hennie T. Brüggenwirth; Ronald van Marion; Hendrikus J. Dubbink; Dion Paridaens; Nicole C. Naus; Annelies de Klein; Emine Kiliç; for the Rotterdam Ocular Melanoma Study Group (ROMS),
TAGS: mutation, genes, neoplasm metastasis, ploidies, polyploidy, neoplasms, intraocular melanoma, bap1 gene
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):2232-2239. doi: 10.1167/iovs.15-18608

Includes: Supplemental Content

Anatomy and Pathology/Oncology September 2014

Prevalence and Implications of TERT Promoter Mutation in Uveal and Conjunctival Melanoma and in Benign and Premalignant Conjunctival Melanocytic Lesions

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Anna E. Koopmans; Kimberley Ober; Hendrikus J. Dubbink; Dion Paridaens; Nicole C. Naus; Stephan Belunek; Bart Krist; Edward Post; Ellen C. Zwarthoff; Annelies de Klein; Robert M. Verdijk
TAGS: mutation, precancerous conditions, conjunctiva, prevalence, uvea, malignant melanoma of conjunctiva, intraocular melanoma, atypical, eye melanomas
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):6024-6030. doi: 10.1167/iovs.14-14901

Anatomy and Pathology/Oncology March 2014

The Prognostic Value of Extraocular Extension in Relation to Monosomy 3 and Gain of Chromosome 8q in Uveal Melanoma

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Jackelien G. M. van Beek; Anna E. Koopmans; Jolanda Vaarwater; Johan J. de Rooi; Dion Paridaens; Nicole C. Naus; Annelies de Klein; Robert M. Verdijk; Emine Kiliç
TAGS: chromosomes, monosomy, neoplasm metastasis, neoplasms, intraocular melanoma, diameter, extension
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1284-1291. doi: 10.1167/iovs.13-13670

Genetics May 2012

Higher Percentage of FISH-Determined Monosomy 3 and 8q Amplification in Uveal Melanoma Cells relate to Poor Patient Prognosis

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Thomas van den Bosch; Jackelien G. M. van Beek; Jolanda Vaarwater; Robert M. Verdijk; Nicole C. Naus; Dion Paridaens; Annelies de Klein; Emine Kiliç
TAGS: chromosomes, monosomy, neoplasms, intraocular melanoma, amplification
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):2668-2674. doi: 10.1167/iovs.11-8697

Anatomy and Pathology/Oncology February 2009

Chromosome 3 Intratumor Heterogeneity in Uveal Melanoma

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Hanneke W. Mensink; Jolanda Vaarwater; Emine Kiliç; Nicole C. Naus; Neeltje Mooy; Gre Luyten; Hennie T. Brüggenwirth; Dion Paridaens; Annelies de Klein
TAGS: heterogeneity, chromosomes, human, pair 3, monosomy, paraffin, body tissue, neoplasms, intraocular melanoma, ulnar-mammary syndrome, intratumoral route of administration
Invest. Ophthalmol. Vis. Sci.. 2009; 50(2):500-504. doi: 10.1167/iovs.08-2279

Biochemistry and Molecular Biology October 2008

Gene Expression Profiling in Uveal Melanoma: Two Regions on 3p Related to Prognosis

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Walter van Gils; Elisabeth M. Lodder; Hanneke W. Mensink; Emine Kiliç; Nicole C. Naus; Hennie T. Brüggenwirth; Wilfred van IJcken; Dion Paridaens; Gregorius P. Luyten; Annelies de Klein
TAGS: gene expression, chromosomes, gene expression profiling, genes, neoplasms, intraocular melanoma, ulnar-mammary syndrome
Invest. Ophthalmol. Vis. Sci.. 2008; 49(10):4254-4262. doi: 10.1167/iovs.08-2033

Includes: Supplemental Content

Anatomy and Pathology/Oncology July 2005

Concurrent Loss of Chromosome Arm 1p and Chromosome 3 Predicts a Decreased Disease-Free Survival in Uveal Melanoma Patients

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Emine Kilic; Nicole C. Naus; Walter van Gils; Caroline C. Klaver; Marjan E. van Til; Michael M. Verbiest; Theo Stijnen; Cornelia M. Mooy; Dion Paridaens; H. Berna Beverloo; Gregorius P. Luyten; Annelies de Klein
TAGS: fluorescent in situ hybridization, chromosomes, chromosomes, human, pair 3, cytogenetic analysis, neoplasm metastasis, neoplasms, intraocular melanoma, arm of chromosome
Invest. Ophthalmol. Vis. Sci.. 2005; 46(7):2253-2257. doi: 10.1167/iovs.04-1460

Clinical and Epidemiologic Research August 2002

Cellular Radiosensitivity of Primary and Metastatic Human Uveal Melanoma Cell Lines

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Gerard J. M. J. van den Aardweg; Nicole C. Naus; Anette C. A. Verhoeven; Annelies de Klein; Gregorius P. M. Luyten
TAGS: cell lines, radiation tolerance, malignant melanoma, cutaneous, intraocular melanoma
Invest. Ophthalmol. Vis. Sci.. 2002; 43(8):2561-2565. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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