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ARVO Annual Meeting Abstract July 2019

Effects of a Rho kinase inhibitor on epithelial wound healing of a mouse cornea

Yukihisa Takada; Osamu Yamanaka; Yuka Okada; Takayoshi Sumioka; Tadahiko Tamura; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3225. doi:

ARVO Annual Meeting Abstract July 2018

Impairment of cornea epithelial wound healing in a Tenasin X-deficient mouse

Takayoshi Sumioka; Yuka Okada; Osamu Yamanaka; Masayasu Miyajima; Ken-ichi Matsumoto; Shizuya Saika; HIroki Iwanishi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4353. doi:

ARVO Annual Meeting Abstract July 2018

Endogenous Sonic hedgehog involvement in corneal epithelial cell proliferation in response to injury in mice

Kana Ichikawa; Yuka Okada; Osamu Yamanaka; Chia-Yang Liu; Winston W Y Kao; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4419. doi:

ARVO Annual Meeting Abstract June 2017

Fragility of corneal epithelium induced by cornea-specific loss of plakoglobin in mice

Masahide Kokado; Masayasu Miyajima; Yuka Okada; Osamu Yamanaka; Chia-Yang Liu; Winston W Y Kao; Weinian Shou; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2618. doi:

ARVO Annual Meeting Abstract June 2017

Effects of travoprost on ZO-1 expression in corneal epithelial cells in vitro

Yukihisa Takada; Osamu Yamanaka; Yuka Okada; Takayoshi Sumioka; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2623. doi:

ARVO Annual Meeting Abstract June 2017

Upregulation of amphiregulin, a ligand of EGFR, in healing mouse conjunctiva after incision and in cultured fibroblasts treated with TGFb1

Hiroki Nidegawa; Osamu Yamanaka; Yukihisa Takada; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4363. doi:

ARVO Annual Meeting Abstract September 2016

Acceleration of EGF expression and related cell behaviors induced by travoprost were cancelled by further addition of an EGF receptor inhibitor in corneal epithelium

Yukihisa Takada; Osamu Yamanaka; Takayoshi Sumioka; Yuka Okada; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1251. doi:

ARVO Annual Meeting Abstract September 2016

Phenotype of corenal epithelium-specific deletion of plakoglobin in mice; morphology and wound healing

Masahide Kokado; Masayasu Miyajima; Yuka Okada; Osamu Yamanaka; Chia-Yang Liu; Winston W Y Kao; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4924. doi:

ARVO Annual Meeting Abstract September 2016

Relation of Tenascin X and VEGF in the corneal cauterization model

Takayoshi Sumioka; Yuka Okada; Osamu Yamanaka; Yuka Nidegawa; Masayasu Miyajima; Ken-ichi Matsumoto; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3525. doi:

ARVO Annual Meeting Abstract June 2015

T r avoprost promotes EGF expression in cultured corneal epithelial cells and alters proliferation and E-cadherin expression in epithelium of an organ-cultured mouse cornea.

Yukihisa Takada; Osamu Yamanaka; Takayoshi Sumioka; Yuka Okada; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5630. doi:

ARVO Annual Meeting Abstract June 2015

Loss of tenascin X suppresses expression of VEGF in macrophages and of TGF b 1 in ocular fibroblasts in vitro; possible mechanism of inhibition of neovascularization in cornea

Takayoshi Sumioka; Yuka Okada; Ken-ichi Matsumoto; Osamu Yamanaka; Masayasu Miyajima; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4498. doi:

Biochemistry and Molecular Biology June 2014

Effects of the Loss of Conjunctival Muc16 on Corneal Epithelium and Stroma in Mice

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Kumi Shirai; Yuka Okada; Dong-Joo Cheon; Masayasu Miyajima; Richard R. Behringer; Osamu Yamanaka; Shizuya Saika
TAGS: conjunctiva, cornea, corneal epithelium, mice
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3626-3637. doi: https://doi.org/10.1167/iovs.13-12955

Cornea May 2014

Impairment of Corneal Epithelial Wound Healing in a TRPV1-Deficient Mouse

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Takayoshi Sumioka; Yuka Okada; Peter S. Reinach; Kumi Shirai; Masayasu Miyajima; Osamu Yamanaka; Shizuya Saika
TAGS: cornea, epithelium, interleukin-6, mice, substance p, trpv1 receptor, wound healing, healing process, debridement, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2014; 55(5):3295-3302. doi: https://doi.org/10.1167/iovs.13-13077

ARVO Annual Meeting Abstract April 2014

Lacking Smad3 attenuates development of Argon laser-induced CNV in mice.

Hiroki Iwanishi; Takayoshi Sumioka; Yuka Okada; Osamu Yamanaka; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1196. doi:

ARVO Annual Meeting Abstract April 2014

Effects of β-catenin inhibitor, ICG-001, on cultured human conjunctival fibroblast

Osamu Yamanaka; Winston W Y Kao; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3200. doi:

ARVO Annual Meeting Abstract April 2014

Loss of Muc16 induces activates Stat3 signal and IL-6 expression in conjunctiva and secondarily affects corneal wound healing in mice.

Shizuya Saika; Kumi Shiai; Yuka Okada; Masayasu Miyajima; Richard R Behringer; Osamu Yamanaka

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3650. doi:

ARVO Annual Meeting Abstract June 2013

TNFα is required for normal tissue repair in injured mouse conjunctiva

Osamu Yamanaka; Ai Kitano; Yuka Okada; Winston Kao; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2111. doi:

ARVO Annual Meeting Abstract June 2013

Lumican Is Required for Epithelium Migration during Healing of Corneal Epithelium Debridement

Jianhua Zhang; Vivien Coulson-Thomas; Yong Yuan; Osamu Yamanaka; Hongshan Liu; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2568. doi:

Cornea May 2013

Increased Fragility, Impaired Differentiation, and Acceleration of Migration of Corneal Epithelium of Epiplakin-Null Mice

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Masahide Kokado; Yuka Okada; Mizuki Goto; Kazushi Ishikawa; Takeshi Miyamoto; Osamu Yamanaka; Sakuhei Fujiwara; Shizuya Saika
TAGS: corneal epithelium, diffuse palmoplantar keratoderma, mice, epithelium, cornea
Invest. Ophthalmol. Vis. Sci.. 2013; 54(5):3780-3789. doi: https://doi.org/10.1167/iovs.12-11077

Glaucoma March 2013

Targeted Overexpression of TGF-α in the Corneal Epithelium of Adult Transgenic Mice Induces Changes in Anterior Segment Morphology and Activates Noncanonical Wnt Signaling

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Yong Yuan; Lung-Kun Yeh; Hongshan Liu; Osamu Yamanaka; William D. Hardie; Winston W.-Y. Kao; Chia-Yang Liu
TAGS: adult, cornea, corneal epithelium, endothelium, language morphology, mice, mice, transgenic, morphology, protein overexpression, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1829-1837. doi: https://doi.org/10.1167/iovs.12-11477

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Effects of a Rho kinase inhibitor on epithelial wound healing of a mouse cornea

Impairment of cornea epithelial wound healing in a Tenasin X-deficient mouse

Endogenous Sonic hedgehog involvement in corneal epithelial cell proliferation in response to injury in mice

Fragility of corneal epithelium induced by cornea-specific loss of plakoglobin in mice

Effects of travoprost on ZO-1 expression in corneal epithelial cells in vitro

Upregulation of amphiregulin, a ligand of EGFR, in healing mouse conjunctiva after incision and in cultured fibroblasts treated with TGFb1

Acceleration of EGF expression and related cell behaviors induced by travoprost were cancelled by further addition of an EGF receptor inhibitor in corneal epithelium

Phenotype of corenal epithelium-specific deletion of plakoglobin in mice; morphology and wound healing

Relation of Tenascin X and VEGF in the corneal cauterization model

T r avoprost promotes EGF expression in cultured corneal epithelial cells and alters proliferation and E-cadherin expression in epithelium of an organ-cultured mouse cornea.

Loss of tenascin X suppresses expression of VEGF in macrophages and of TGF b 1 in ocular fibroblasts in vitro; possible mechanism of inhibition of neovascularization in cornea

Effects of the Loss of Conjunctival Muc16 on Corneal Epithelium and Stroma in Mice

Impairment of Corneal Epithelial Wound Healing in a TRPV1-Deficient Mouse

Lacking Smad3 attenuates development of Argon laser-induced CNV in mice.

Effects of β-catenin inhibitor, ICG-001, on cultured human conjunctival fibroblast

Loss of Muc16 induces activates Stat3 signal and IL-6 expression in conjunctiva and secondarily affects corneal wound healing in mice.

TNFα is required for normal tissue repair in injured mouse conjunctiva

Lumican Is Required for Epithelium Migration during Healing of Corneal Epithelium Debridement

Increased Fragility, Impaired Differentiation, and Acceleration of Migration of Corneal Epithelium of Epiplakin-Null Mice

Targeted Overexpression of TGF-α in the Corneal Epithelium of Adult Transgenic Mice Induces Changes in Anterior Segment Morphology and Activates Noncanonical Wnt Signaling

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