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ARVO Annual Meeting Abstract July 2019

KLF4 regulates corneal epithelial cell cycle progression by suppressing canonical TGF-β signaling, and upregulating CDK inhibitors P16 and P27

Anil Tiwari; Sudha Swamynathan; Nicholas Alexander; John Sabastian Gnalian; Shenghuo Tien; Paul R Kinchington; Swamynathan Shivalingappa K

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5106. doi:

ARVO Annual Meeting Abstract July 2019

Manipulating Gene Expression of Human Lamina Cribrosa Cells and Astrocytes

Jr-Jiun Liou; Shenghuo Tien; Michael Yee; Paul R Kinchington; Christopher A Girkin; Jonathan Pieter Vande Geest

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6070. doi:

Cornea February 2019

KLF4 Regulates Corneal Epithelial Cell Cycle Progression by Suppressing Canonical TGF-β Signaling and Upregulating CDK Inhibitors P16 and P27

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Anil Tiwari; Sudha Swamynathan; Nicholas Alexander; John Gnalian; Shenghe Tian; Paul R. Kinchington; Shivalingappa K. Swamynathan
TAGS: corneal epithelial cells, corneal epithelium, cyclin-dependent kinase inhibitors, signal transduction, cornea, rna, ablation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):731-740. doi: https://doi.org/10.1167/iovs.18-26423

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

A rat model of facial Post Herpetic Neuralgia (PHN) induced by Varicella Zoster Virus (VZV)

Paul R Kinchington; Benjamin Warner; William Goins; Mahesh Rao; Crystal Stinson; Phillip Kramer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2990. doi:

ARVO Annual Meeting Abstract June 2017

The Impact of Ocular Pathogens on Autophagy

Kimberly Brothers; Shenghuo Tian; Paul R Kinchington; Regis P Kowalski; Robert M Q Shanks

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5760. doi:

ARVO Annual Meeting Abstract April 2014

Ganglionic CD8 T Cells Associated with HSV-1 Latency in the Murine Ocular Infection Model Show Increased Functionality in the Absence of Immunodominant CD8s and are Entirely HSV-1 Specific

Paul R Kinchington; Benjamin Treat; Sarah Bidula; Robert L Hendricks

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4060. doi:

Research Highlight February 2014

Targeting Host Pathways to Block HSV-1 at the Cornea

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Paul R. Kinchington

Invest. Ophthalmol. Vis. Sci.. 2014; 55(2):716. doi: https://doi.org/10.1167/iovs.14-13879

ARVO Annual Meeting Abstract March 2012

Treatment of VZV-induced Chronic Pain in a Rat Model of Post-Herpetic Neuralgia Using Replication Defective HSV-1 Expressing the Tonal Modulator Proenkephalin

Paul R. Kinchington; Michael B. Yee; Mingdi Zhang; William F. Goins

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6159. doi:

ARVO Annual Meeting Abstract April 2011

A Compensatory CD8+T Cell Response In C57BL/6 Mice Trigeminal Ganglia Following Ocular Infection With HSV-1 Lacking The Immunodominant Epitope

Paul R. Kinchington; Sarah M. Bidula; Anthony J. St. Leger; Srividya Ramachandran; Bjoern Peters; John Sidney; Alessandro Sette; Robert L. Hendricks

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3007. doi:

ARVO Annual Meeting Abstract April 2010

CD8+T Cells Directed to a "True Late" Viral Antigen, Made After Onset of Viral DNA Replication, Can Still Block HSV-1 Reactivation From Latency

P. R. Kinchington; S. Ramachandran; K. Davoli; R. L. Hendricks

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):6336. doi:

ARVO Annual Meeting Abstract April 2009

Cellular Targets of a Viral Protein Kinase Required for Growth of Varicella Zoster Virus in Primary Corneal Fibroblasts

P. R. Kinchington; A. Erazo; M. Walters

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3872. doi:

ARVO Annual Meeting Abstract May 2008

Acute Ocular and Trigeminal Ganglionic Replication of Herpes Simplex Virus Type 1 Are Attenuated by Conversion of Glycoprotein B From a "Leaky Late" to a "True-Late" Regulated Gene

P. R. Kinchington; K. Davoli; S. Ramachandan; V. Imbrogno; R. L. Hendricks

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2486. doi:

Immunology and Microbiology August 2007

Identification of Viral Antigens Recognized by Ocular Infiltrating T Cells from Patients with Varicella Zoster Virus-Induced Uveitis

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Johannes C. M. Milikan; Paul R. Kinchington; G. Seerp Baarsma; Robert W. A. M. Kuijpers; Albert D. M. E. Osterhaus; Georges M. G. M. Verjans
TAGS: antigens, antigens, viral, chickenpox, t-lymphocytes, uveitis, viruses, proteins, human leukocyte antigens, cytokine
Invest. Ophthalmol. Vis. Sci.. 2007; 48(8):3689-3697. doi: https://doi.org/10.1167/iovs.07-0020

ARVO Annual Meeting Abstract May 2007

Identifying Sulfotransferase and Glycosyltransferase Genes Responsible for Regulation of Corneal Keratan Sulfate Biosynthesis

J. L. Funderburgh; M. M. Mann; P. R. Kinchington; M. L. Funderburgh

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1482. doi:

ARVO Annual Meeting Abstract May 2007

Ocular Infiltrating CD4+ T Cells From Patients With Varicella Zoster Virus (VZV) Uveitis Recognize Latency Associated VZV Proteins

G. M. Verjans; J. C. Milikan; S. G. Baarsma; R. W. A. M. Kuijpers; P. R. Kinchington; A. D. M. E. Osterhaus

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1501. doi:

Immunology and Microbiology July 2001

The Antiviral Resistance and Replication of Cidofovir-Resistant Adenovirus Variants in the New Zealand White Rabbit Ocular Model

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Eric G. Romanowski; Y. Jerold Gordon; Trinita Araullo-Cruz; Kathleen A. Yates; Paul R. Kinchington
TAGS: adenoviruses, cidofovir, drug resistance, viral, new zealand, oryctolagus cuniculus, viruses
Invest. Ophthalmol. Vis. Sci.. 2001; 42(8):1812-1815. doi:

Articles June 1998

A Rho-associated protein kinase: differentially distributed in limbal and corneal epithelia.

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N SundarRaj; P R Kinchington; H Wessel; B Goldblatt; J Hassell; J P Vergnes; S C Anderson
TAGS: corneal epithelium, protein kinase
Invest. Ophthalmol. Vis. Sci.. 1998; 39(7):1266-1272. doi:

Articles December 1996

Isolation of human adenovirus type 5 variants resistant to the antiviral cidofovir.

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Y J Gordon; T P Araullo-Cruz; Y F Johnson; E G Romanowski; P R Kinchington
TAGS: adenoviruses, human, antiviral agents, cidofovir, patient isolation, social isolation
Invest. Ophthalmol. Vis. Sci.. 1996; 37(13):2774-2778. doi:

Articles November 1994

Use of polymerase chain amplification reaction for the detection of adenoviruses in ocular swab specimens.

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P R Kinchington; S E Turse; R P Kowalski; Y J Gordon
TAGS: adenoviruses, amplification
Invest. Ophthalmol. Vis. Sci.. 1994; 35(12):4126-4134. doi:

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KLF4 regulates corneal epithelial cell cycle progression by suppressing canonical TGF-β signaling, and upregulating CDK inhibitors P16 and P27

Manipulating Gene Expression of Human Lamina Cribrosa Cells and Astrocytes

KLF4 Regulates Corneal Epithelial Cell Cycle Progression by Suppressing Canonical TGF-β Signaling and Upregulating CDK Inhibitors P16 and P27

A rat model of facial Post Herpetic Neuralgia (PHN) induced by Varicella Zoster Virus (VZV)

The Impact of Ocular Pathogens on Autophagy

Ganglionic CD8 T Cells Associated with HSV-1 Latency in the Murine Ocular Infection Model Show Increased Functionality in the Absence of Immunodominant CD8s and are Entirely HSV-1 Specific

Targeting Host Pathways to Block HSV-1 at the Cornea

Treatment of VZV-induced Chronic Pain in a Rat Model of Post-Herpetic Neuralgia Using Replication Defective HSV-1 Expressing the Tonal Modulator Proenkephalin

A Compensatory CD8+T Cell Response In C57BL/6 Mice Trigeminal Ganglia Following Ocular Infection With HSV-1 Lacking The Immunodominant Epitope

CD8+T Cells Directed to a "True Late" Viral Antigen, Made After Onset of Viral DNA Replication, Can Still Block HSV-1 Reactivation From Latency

Cellular Targets of a Viral Protein Kinase Required for Growth of Varicella Zoster Virus in Primary Corneal Fibroblasts

Acute Ocular and Trigeminal Ganglionic Replication of Herpes Simplex Virus Type 1 Are Attenuated by Conversion of Glycoprotein B From a "Leaky Late" to a "True-Late" Regulated Gene

Identification of Viral Antigens Recognized by Ocular Infiltrating T Cells from Patients with Varicella Zoster Virus-Induced Uveitis

Identifying Sulfotransferase and Glycosyltransferase Genes Responsible for Regulation of Corneal Keratan Sulfate Biosynthesis

Ocular Infiltrating CD4+ T Cells From Patients With Varicella Zoster Virus (VZV) Uveitis Recognize Latency Associated VZV Proteins

The Antiviral Resistance and Replication of Cidofovir-Resistant Adenovirus Variants in the New Zealand White Rabbit Ocular Model

A Rho-associated protein kinase: differentially distributed in limbal and corneal epithelia.

Isolation of human adenovirus type 5 variants resistant to the antiviral cidofovir.

Use of polymerase chain amplification reaction for the detection of adenoviruses in ocular swab specimens.

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