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ARVO Annual Meeting Abstract June 2025

Partial epigenetic reprogramming protects induced pluripotent stem cell (iPSC)-derived retinal pigment epithelial (RPE) cells from oxidized low-density lipoprotein-induced damage

Lorena Rodriguez Martinez; Suman Chaudhary; Jean Moon; Patricia A D'Amore; Zhengping Hu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5285.

ARVO Annual Meeting Abstract June 2025

PMC, a sterically hindered phenol compound, rescues retinal pigment epithelial (RPE) cells from oxidative stress-induced damage

Suman Chaudhary; Yin-Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3767.

ARVO Annual Meeting Abstract June 2024

Endomucin’s regulation of clathrin-mediated endocytosis through the AP2 complex is specific for VEGFR2

Zhengping Hu; Issahy Cano; Melissa Wild; Suman Chaudhary; Urvi Gupta; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3269.

ARVO Annual Meeting Abstract June 2024

Genome-wide Screening Identifies Novel Genetic and Epigenetic Factors for the Rejuvenation and Enhancement of RPE to Alleviate Age-related Macular Degeneration

Yuancheng Ryan Lu; Margarete Karg; Lindsey A Chew; Kat Kajderowicz; Daisy Y Shu; Xiaojie Qiu; Nasrin Refaian; Shintaro Shirahama; Zhengping Hu; Tessa Bertozzi; David Sinclair; Magali Saint-Geniez; Patricia A D'Amore; Catherine Bowes Rickman; Bruce Ksander; Jonathan Weissman

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5307.

ARVO Annual Meeting Abstract June 2024

Role of endomucin in angiogenesis and cytoskeletal organization

Jean Moon; Zhengping Hu; John Fornagiel; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4989.

ARVO Annual Meeting Abstract June 2024

Role of PMC (2,2,5,7,8-pentamethyl-6-chromanol), a sterically hindered phenol, in rescuing oxidized low-density lipoprotein (ox-LDL) induced cytotoxicity in human retinal pigment epithelial cells

Suman Chaudhary; Daisy Y Shu; Maria Chiara Rivolta; Emil Kriukov; Sergio Pestun; Petr Y Baranov; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6515.

ARVO Annual Meeting Abstract June 2023

Endomucin deletion leads to disorganized choroidal capillary fenestration and reduces laser-induced choroidal neovascularization in mice

Zhengping Hu; Issahy Cano; Anton Lennikov; Melissa Wild; Urvi Gupta; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3005.

ARVO Annual Meeting Abstract June 2022

Endomucin deletion delays retinal vascular development and inhibits neovascularization in oxygen-induced retinopathy

Zhengping Hu; Issahy Cano; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3167 – F0441.

ARVO Annual Meeting Abstract June 2022

Blood-Retinal -Barrier 3D Model Using Microfabricated Porous Scaffolds

Karen Yud Torrejon; Andrea Unser; Hira Afzaal; Hunter Williams; Feryan Ahmed; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3155 – F0429.

ARVO Annual Meeting Abstract June 2022

Therapeutic effect of hindered phenol compound in a solid lipid nanoparticle formulation in mouse models of dry AMD

Yin Shan Eric Ng; Zhenyu Ji; Anthoula Arta; Yu Su; Andrew James Urquhart; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4286.

ARVO Annual Meeting Abstract June 2021

Specific Role of Endomucin in VEGF-induced VEGF Receptor 2 Internalization and Function

Zhengping Hu; Issahy Cano; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2925.

ARVO Annual Meeting Abstract June 2021

Galectin-3 requires VEGF to activate VEGF receptor 2 in retinal endothelial cells

Issahy Cano; Zhengping Hu; Dina Abusamra; Magali Saint-Geniez; Yin Shan Eric Ng; Pablo Argueso; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2702.

ARVO Annual Meeting Abstract June 2021

Time Series Data Analysis of Gene Expression with Age in Mouse Retinal Pigment Epithelium

Sudeep Mehrotra; Gopalan Gnanaguru; Patricia A D'Amore; Ayellet V Segre

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3114.

ARVO Annual Meeting Abstract July 2019

Solid lipid nanoparticles for the delivery of a sustained-release small molecule antioxidant for RPE protection in dry AMD

Anthoula Arta; Yu Su; Franco Aparecido Rossato; Gopalan Gnanaguru; Patricia A. D'Amore; Yin Shan Eric Ng; Andrew J Urquhart

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1705.

ARVO Annual Meeting Abstract July 2019

Endomucin and galectin-3 modulate VEGFR2-mediated endothelial functions

Michelle LeBlanc; Issahy Cano; Zhengping Hu; kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Pablo Argueso; Patricia A. D'Amore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3259.

ARVO Annual Meeting Abstract July 2019

Endomucin regulates Vascular Endothelial Growth Factor (VEGF) induced endothelium functions through its extracellular domain

Zhengping Hu; Michelle LeBlanc; kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A. D'Amore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5376.

ARVO Annual Meeting Abstract July 2018

Inactive Cas9 blocks vitreous-induced contraction of retinal pigment epithelial cells

Zhengping Hu; Na Chen; Patricia A D'Amore; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5254.

ARVO Annual Meeting Abstract July 2018

Idelalisib inhibits neovascularization in a mouse model of oxygen-induced retinopathy

wenyi wu; Guohong Zhou; Xionggao Huang; Patricia A D'Amore; Shizuo Mukai; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5299.

ARVO Annual Meeting Abstract July 2018

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Michelle LeBlanc; Kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5481.

Biochemistry and Molecular Biology December 2017

AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro

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Wenyi Wu; Yajian Duan; Gaoen Ma; Guohong Zhou; Cindy Park-Windhol; Patricia A. D'Amore; Hetian Lei
TAGS: crispr, vascular endothelial growth factor a, vascular endothelial growth factor receptor-2, angiogenesis
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6082-6090. https://doi.org/10.1167/iovs.17-21902

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Partial epigenetic reprogramming protects induced pluripotent stem cell (iPSC)-derived retinal pigment epithelial (RPE) cells from oxidized low-density lipoprotein-induced damage

PMC, a sterically hindered phenol compound, rescues retinal pigment epithelial (RPE) cells from oxidative stress-induced damage

Endomucin’s regulation of clathrin-mediated endocytosis through the AP2 complex is specific for VEGFR2

Genome-wide Screening Identifies Novel Genetic and Epigenetic Factors for the Rejuvenation and Enhancement of RPE to Alleviate Age-related Macular Degeneration

Role of endomucin in angiogenesis and cytoskeletal organization

Role of PMC (2,2,5,7,8-pentamethyl-6-chromanol), a sterically hindered phenol, in rescuing oxidized low-density lipoprotein (ox-LDL) induced cytotoxicity in human retinal pigment epithelial cells

Endomucin deletion leads to disorganized choroidal capillary fenestration and reduces laser-induced choroidal neovascularization in mice

Endomucin deletion delays retinal vascular development and inhibits neovascularization in oxygen-induced retinopathy

Blood-Retinal -Barrier 3D Model Using Microfabricated Porous Scaffolds

Therapeutic effect of hindered phenol compound in a solid lipid nanoparticle formulation in mouse models of dry AMD

Specific Role of Endomucin in VEGF-induced VEGF Receptor 2 Internalization and Function

Galectin-3 requires VEGF to activate VEGF receptor 2 in retinal endothelial cells

Time Series Data Analysis of Gene Expression with Age in Mouse Retinal Pigment Epithelium

Solid lipid nanoparticles for the delivery of a sustained-release small molecule antioxidant for RPE protection in dry AMD

Endomucin and galectin-3 modulate VEGFR2-mediated endothelial functions

Endomucin regulates Vascular Endothelial Growth Factor (VEGF) induced endothelium functions through its extracellular domain

Inactive Cas9 blocks vitreous-induced contraction of retinal pigment epithelial cells

Idelalisib inhibits neovascularization in a mouse model of oxygen-induced retinopathy

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro

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