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ARVO Annual Meeting Abstract July 2018

Inactive Cas9 blocks vitreous-induced contraction of retinal pigment epithelial cells

Zhengping Hu; Na Chen; Patricia A D'Amore; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5254. doi:

ARVO Annual Meeting Abstract July 2018

Idelalisib inhibits neovascularization in a mouse model of oxygen-induced retinopathy

wenyi wu; Guohong Zhou; Xionggao Huang; Patricia A D'Amore; Shizuo Mukai; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5299. doi:

ARVO Annual Meeting Abstract July 2018

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Michelle LeBlanc; Kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5481. doi:

Biochemistry and Molecular Biology December 2017

AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro

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Wenyi Wu; Yajian Duan; Gaoen Ma; Guohong Zhou; Cindy Park-Windhol; Patricia A. D'Amore; Hetian Lei
TAGS: angiogenesis, vascular endothelial growth factor a, vascular endothelial growth factor receptor-2, crispr
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6082-6090. doi: 10.1167/iovs.17-21902

Biochemistry and Molecular Biology October 2017

Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy

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Guohong Zhou; Yajiang Duan; Gaoen Ma; Wenyi Wu; Zhengping Hu; Na Chen; Yewlin Chee; Jing Cui; Arif Samad; Joanne A. Matsubara; Shizuo Mukai; Patricia A. D'Amore; Hetian Lei
TAGS: apoptosis, western blotting, mutation, cell proliferation, oryctolagus cuniculus, vitreoretinopathy, proliferative, vitreous body, epithelial cells, pathogenesis
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5361-5367. doi: 10.1167/iovs.17-22045

ARVO Annual Meeting Abstract June 2017

Chloroquine-induced Retinal Toxicity In Vitro and In Vivo

Dhanesh Amarnani; Eric Kim; Patricia A D'Amore; Leo A Kim

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1608. doi:

ARVO Annual Meeting Abstract June 2017

The PPAR-γ Agonist Troglitazone Protects RPE Cells from Oxidized LDL Induced NLRP3-inflammasome–Mediated Cell Death

Ashley Mackey; Gopalan Gnanaguru; Eun Young Choi; Dhanesh Amarnani; Patricia A D'Amore; Yin Shan Eric Ng

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2288. doi:

ARVO Annual Meeting Abstract June 2017

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Patricia A D'Amore; Cindy Park-Windhol; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4058. doi:

ARVO Annual Meeting Abstract June 2017

Elevated expression of RUNX1 by vascular endothelial cells in proliferative diabetic retinopathy

Jonathan D. Lam; Daniel Oh; Patricia A D'Amore; Leo A Kim; Joseph Arboleda-Velasquez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4249. doi:

ARVO Annual Meeting Abstract June 2017

Retinal pericytes in health and disease

Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4732. doi:

ARVO Annual Meeting Abstract June 2017

The MDM2 T309G mutation in primary human retinal epithelial cells enhances experimental proliferative vitreoretinopathy

wenyi wu; yajiang duan; gaoen ma; Yewlin Chee; Arif Samad; Jing Z Cui; Joanne A Matsubara; Shizuo Mukai; Patricia A D'Amore; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5964. doi:

Biochemistry and Molecular Biology February 2017

Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation

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Xionggao Huang; Guohong Zhou; Wenyi Wu; Gaoen Ma; Patricia A. D'Amore; Shizuo Mukai; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1228-1236. doi: 10.1167/iovs.16-20537

ARVO Annual Meeting Abstract September 2016

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Patricia A D'Amore; Cindy Park-Windhol; Yin Shan Eric Ng; Jinling Yang; Vincent Primo; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3637. doi:

ARVO Annual Meeting Abstract September 2016

Chloroquine toxicity of the retinal pigment epithelium and retina in vitro and a mouse model of retinal toxicity

Dhanesh Amarnani; Leo A Kim; Patricia A D'Amore; Lindsay Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6040. doi:

ARVO Annual Meeting Abstract September 2016

CD36-mediated uptake of oxidized LDL induces retinal pigment epithelial cell death through NLRP3 inflammasome activation

Gopalan Gnanaguru; Ariel Choi; Dhanesh Amarnani; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6556. doi:

ARVO Annual Meeting Abstract September 2016

A novel quantitative tool for the analysis of vascular phenotypes via fluorescein angiograms quantifies reduced arterial-venous vessel patterning

Alex A Bigger-Allen; Joseph Arboleda-Velasquez; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1775. doi:

ARVO Annual Meeting Abstract September 2016

The CRISPR/Cas9-created MDM2 T309G contributes to the vitreous-induced cellular responses intrinsic to proliferative vitreoretinopathy

Gaoen Ma; Yajian Duan; Xionggao Huang; Patricia A D'Amore; Hetian Lei

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5367. doi:

Retinal Cell Biology September 2016

Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

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Gopalan Gnanaguru; Ariel R. Choi; Dhanesh Amarnani; Patricia A. D'Amore
TAGS: low-density lipoproteins, lipoproteins, cd36 antigens, inflammasomes, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4704-4712. doi: 10.1167/iovs.15-18663

Includes: Supplemental Content

Biochemistry and Molecular Biology July 2016

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases

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Gaoen Ma; Yajian Duan; Xionggao Huang; Cynthia X. Qian; Yewlin Chee; Shizuo Mukai; Jing Cui; Arif Samad; Joanne Aiko Matsubara; Andrius Kazlauskas; Patricia A. D'Amore; Shuyan Gu; Hetian Lei
TAGS: western blotting, cell proliferation, phosphates, phosphatidylinositols, phosphotransferases, oryctolagus cuniculus, vitreoretinopathy, proliferative, vitreous body, mice, prevention
Invest. Ophthalmol. Vis. Sci.. 2016; 57(8):3935-3943. doi: 10.1167/iovs.16-19405

ARVO Annual Meeting Abstract June 2015

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

Jinling Yang; Magali Saint-Geniez; Yin Shan Eric Ng; Marsha A. Moses; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3104. doi:

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Inactive Cas9 blocks vitreous-induced contraction of retinal pigment epithelial cells

Idelalisib inhibits neovascularization in a mouse model of oxygen-induced retinopathy

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro

Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy

Chloroquine-induced Retinal Toxicity In Vitro and In Vivo

The PPAR-γ Agonist Troglitazone Protects RPE Cells from Oxidized LDL Induced NLRP3-inflammasome–Mediated Cell Death

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Elevated expression of RUNX1 by vascular endothelial cells in proliferative diabetic retinopathy

Retinal pericytes in health and disease

The MDM2 T309G mutation in primary human retinal epithelial cells enhances experimental proliferative vitreoretinopathy

Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Chloroquine toxicity of the retinal pigment epithelium and retina in vitro and a mouse model of retinal toxicity

CD36-mediated uptake of oxidized LDL induces retinal pigment epithelial cell death through NLRP3 inflammasome activation

A novel quantitative tool for the analysis of vascular phenotypes via fluorescein angiograms quantifies reduced arterial-venous vessel patterning

The CRISPR/Cas9-created MDM2 T309G contributes to the vitreous-induced cellular responses intrinsic to proliferative vitreoretinopathy

Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

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