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ARVO Annual Meeting Abstract June 2024

Functional Phenotyping of Mouse Mutants Reveals Novel Genes that Impact the Mammalian Outer Retina

Neal S Peachey; Janine M Wotton; Patsy M Nishina; Jessica Wong; Eric A Pierce; Emily Place; Riccardo Sangermano; Kinga Maria Bujakowska; Mark P Krebs; Jacqueline K White

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1531.

ARVO Annual Meeting Abstract June 2024

Mitochondrial alterations in humanized ARMS2 A69S variant mouse model of age-related macular degeneration (AMD)

Navdeep Gogna; Gayle B Collin; Lillian F Hyde; Lisa Stone; Jürgen K Naggert; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3809.

ARVO Annual Meeting Abstract June 2024

Genetic Modifiers of Crb1 rd8 Retinal Dysplasia Identified in C57BL/6N Single-Gene Knockout Mice

Mark P Krebs; Sonia M Weatherly; Gayle B Collin; Nattaya Damkham; Lillian F Hyde; Lisa Stone; Jürgen K Naggert; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4733.

ARVO Annual Meeting Abstract June 2024

A null mutation in murine Lratd2 disrupts visual function and the structural integrity of the retinal pigment epithelium

Gayle B Collin; Mark P Krebs; Lillian F Hyde; Navdeep Gogna; Nattaya Damkham; Lisa Stone; Patsy M Nishina; Jürgen K Naggert

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6731.

ARVO Annual Meeting Abstract June 2023

A new humanized ARMS2 A69S variant mouse model of age-related macular degeneration (AMD).

Navdeep Gogna; Gayle Collin; Lisa Stone; Juergen Naggert; Patsy M. Nishina

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2724.

ARVO Annual Meeting Abstract June 2023

RPE heterogeneity in aging and disease in mice

Patsy M. Nishina

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2445.

ARVO Annual Meeting Abstract June 2021

Identifying gene interaction effects in Adipor1 and Mfrp double mutant mice

Navdeep Gogna; Sonia Weatherly; Jai Pinkney; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1543.

ARVO Annual Meeting Abstract June 2020

A new mouse model of cone photoreceptor function loss ( cpfl10 ) with normal rod photoreceptor function.

Bo Chang; Jieping Wang; Bernie Fitzmaurice; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):768.

ARVO Annual Meeting Abstract July 2019

A new mouse model of early-onset retinal neovascularization 4 ( rnv4 ).

Bo Chang; Jieping Wang; Bernard Fitzmaurice; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1641.

Genetics October 2018

Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3 , Is Dependent on the Crb1 rd8 Allele

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Bo Chang; Bernard FitzMaurice; Jieping Wang; Benjamin E. Low; Michael V. Wiles; Patsy M. Nishina
TAGS: alleles, mice, mutation, phenotype, vascular diseases, angiogenesis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5127-5139. https://doi.org/10.1167/iovs.18-25046

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

A new mouse model, nob10 , with no b wave and late onset retinal degeneration.

Bo Chang; Jieping Wang; Bernard Fitzmaurice; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2345.

ARVO Annual Meeting Abstract July 2018

Disruption of murine Eml1 results in mislocalization of mitotic neuroblastic cells and early dysplasia of the developing retina

Gayle Collin; Jungyeon Won; Wanda L. Hicks; Juergen K. Naggert; Mark P Krebs; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2346.

ARVO Annual Meeting Abstract September 2016

Mouse models of NMNAT1 -Leber congenital amaurosis recapitulate key features of the human disease

Scott H Greenwald; Jeremy R Charette; Magdalena Staniszewska; Lan Ying Shi; Steve D.M. Brown; Lisa Stone; Wanda Hicks; Michael R. Bowl; Mark P. Krebs; Patsy M Nishina; Eric A Pierce

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2255.

ARVO Annual Meeting Abstract September 2016

The severe neovascular phenotype of a mouse model for Coats-like vasculopathy, rnv3 , is dependent on Crb1 rd8

Patsy M Nishina; Benjamin Low; Jieping Wang; Bernard FitzMaurice; Michael Wiles; Bo Chang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2627.

ARVO Annual Meeting Abstract September 2016

Frmd4b Suppresses Retinal Dysplasia in Nr2e3 rd7 Mice by Restoring the Integrity of External Limiting Membrane

Yang Kong; Jeremy R Charette; Jürgen Naggert; Lihong Zhao; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3148.

ARVO Annual Meeting Abstract September 2016

A protein kinase C theta mutation causes early-onset exudative retinal detachment

Xiaojie Ji; Ye Liu; Ron Hurd; Jieping Wang; Bernard FitzMaurice; Jürgen Naggert; Patsy M Nishina; Bo Chang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5380.

ARVO Annual Meeting Abstract September 2016

Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity

Anneke I Den Hollander; Nicole T.M. Saksens; Mark P Krebs; Elfride De Baere; Frans P Cremers; Camiel J F Boon; Ronald Roepman; Bart Peter Leroy; Neal S Peachey; Carel C B Hoyng; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Mfrp regulates ocular growth in mice and interacts with Prss56

Mark P Krebs; Wanda Hicks; Patsy M Nishina

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3609.

Genetics March 2016

Retinal Pigment Epithelium Atrophy 1 ( rpea1 ): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ

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Xiaojie Ji; Ye Liu; Ron Hurd; Jieping Wang; Bernie Fitzmaurice; Patsy M. Nishina; Bo Chang
TAGS: mice, protein kinase c, protein kinase c-theta, retinal detachment, retinal pigment epithelium atrophy, mutation, homozygote, eye, phenotype
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):877-888. https://doi.org/10.1167/iovs.15-17495

Includes: Supplemental Content

Genetics June 2015

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia

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Dennis M. Maddox; Gayle B. Collin; Akihiro Ikeda; C. Herbert Pratt; Sakae Ikeda; Britt A. Johnson; Ron E. Hurd; Lindsay S. Shopland; Jürgen K. Naggert; Bo Chang; Mark P. Krebs; Patsy M. Nishina
TAGS: electroretinography, homozygote, mice, mutation, neuroglia, neurons, photoreceptors, retina, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):3776-3787. https://doi.org/10.1167/iovs.14-16047

Includes: Supplemental Content

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Functional Phenotyping of Mouse Mutants Reveals Novel Genes that Impact the Mammalian Outer Retina

Mitochondrial alterations in humanized ARMS2 A69S variant mouse model of age-related macular degeneration (AMD)

Genetic Modifiers of Crb1 rd8 Retinal Dysplasia Identified in C57BL/6N Single-Gene Knockout Mice

A null mutation in murine Lratd2 disrupts visual function and the structural integrity of the retinal pigment epithelium

A new humanized ARMS2 A69S variant mouse model of age-related macular degeneration (AMD).

RPE heterogeneity in aging and disease in mice

Identifying gene interaction effects in Adipor1 and Mfrp double mutant mice

A new mouse model of cone photoreceptor function loss ( cpfl10 ) with normal rod photoreceptor function.

A new mouse model of early-onset retinal neovascularization 4 ( rnv4 ).

Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3 , Is Dependent on the Crb1 rd8 Allele

A new mouse model, nob10 , with no b wave and late onset retinal degeneration.

Disruption of murine Eml1 results in mislocalization of mitotic neuroblastic cells and early dysplasia of the developing retina

Mouse models of NMNAT1 -Leber congenital amaurosis recapitulate key features of the human disease

The severe neovascular phenotype of a mouse model for Coats-like vasculopathy, rnv3 , is dependent on Crb1 rd8

Frmd4b Suppresses Retinal Dysplasia in Nr2e3 rd7 Mice by Restoring the Integrity of External Limiting Membrane

A protein kinase C theta mutation causes early-onset exudative retinal detachment

Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity

Mfrp regulates ocular growth in mice and interacts with Prss56

Retinal Pigment Epithelium Atrophy 1 ( rpea1 ): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia

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