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ARVO Annual Meeting Abstract June 2024

Involvement of cytoskeletal motor proteins in nuclear reorganization during lens fiber cell differentiation

Elizabeth Whitcomb; Paul G FitzGerald; Allen Taylor; Sheldon Rowan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1477.

ARVO Annual Meeting Abstract June 2024

Using CRISPR mutants to gain insight into the role of the caspase cleavage site in murine filensin

Paul G FitzGerald

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3228.

ARVO Annual Meeting Abstract June 2022

Lamin phosphorylation directs nuclear condensation and nuclear envelope reorganization during lens differentiation

Elizabeth A Whitcomb; Giuliana Perini-Villanueva; Sarah Francisco; Marc Kantorow; Lisa A Brennan; Paul G FitzGerald; Allen Taylor

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3108.

Lens December 2021

Aged Nrf2-Null Mice Develop All Major Types of Age-Related Cataracts

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Sheldon Rowan; Shuhong Jiang; Sarah G. Francisco; Laura C. D. Pomatto; Zhiwei Ma; Xiaodong Jiao; Maria M. Campos; Sandeep Aryal; Shaili D. Patel; Binapani Mahaling; S. Amer Riazuddin; Elia J. Duh; Salil A. Lachke; J. Fielding Hejtmancik; Rafael de Cabo; Paul G. FitzGerald; Allen Taylor
TAGS: cataract, cataract, senile, lens (device), lens, crystalline, mice
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):10. https://doi.org/10.1167/iovs.62.15.10

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Age-related cataracts in mice lacking the Nrf2 antioxidant transcription factor

Sheldon Rowan; Shuhong Jiang; Paul G FitzGerald; Binapani Mahaling; Elia J Duh; Allen Taylor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1028.

ARVO Annual Meeting Abstract July 2019

Altered ubiquitin signaling in mammalian lens development causes metabolic and mitochondrial dysfunction leading to cataractogenesis

Sheldon Rowan; Elizabeth Whitcomb; Eloy Bejarano; Fu Shang; Ke Liu; Rebecca L Pfeiffer; Roberto Calitri; James D Baleja; Bryan W Jones; Paul G FitzGerald; Allen Taylor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1383.

ARVO Annual Meeting Abstract June 2017

Characterization of the cornea in the YAP -/+ mouse

Soohyun Kim; Sara M Thomasy; Vijay Krishna Raghunathan; Paul G FitzGerald; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1418.

ARVO Annual Meeting Abstract June 2017

Myo/Nog Cells are Present on the Zonules Between the Ciliary Body and Lens

Jacquelyn V Gerhart; Paul G FitzGerald; Robert Getts; Liliana Werner; Nick Mamalis; Mindy George-Weinstein

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3635.

ARVO Annual Meeting Abstract June 2017

Deletion of GLUT1 in mouse lens epithelium leads to cataract formation

Aditi Swarup; Arturo Bravo-Nuevo; Jamie Soto; E. Dale Abel; Brent A Bell; Neal Peachey; Paul G FitzGerald; Nancy J Philp

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2038.

ARVO Annual Meeting Abstract September 2016

Tropomodulin 1 regulation of actin is required for the formation of large paddle protrusions between mature lens fiber cells

Velia M Fowler; Catherine Cheng; Roberta B Nowak; Sondip K Biswas; Woo-Kuen Lo; Paul G FitzGerald

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3073.

ARVO Annual Meeting Abstract September 2016

AQP0 AND BEADED FILAMENT PROTEINS ARE CRITICAL FOR OCULAR LENS BIOMECHANICS

Kulandaiappan Varadaraj; Richard Mathias; Paul G FitzGerald; Alan Shiels; Nikol Palomino; Sindhu S Kumari

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

Lens August 2016

Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells

PDF

Catherine Cheng; Roberta B. Nowak; Sondip K. Biswas; Woo-Kuen Lo; Paul G. FitzGerald; Velia M. Fowler
TAGS: actins, lens (device), lens, crystalline, spectrin
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4084-4099. https://doi.org/10.1167/iovs.16-19949

Genetics August 2015

Characterization of an Early-Onset, Autosomal Recessive, Progressive Retinal Degeneration in Bengal Cats

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Ron Ofri; Christopher M. Reilly; David J. Maggs; Paul G. Fitzgerald; Yael Shilo-Benjamini; Kathryn L. Good; Robert A. Grahn; Danielle D. Splawski; Leslie A. Lyons
TAGS: adaptive testing, autosomal recessive inheritance, cats, retinal degeneration, electroretinography, breeding, eye
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5299-5308. https://doi.org/10.1167/iovs.15-16585

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Links Between Ubiquitin Biology, Calcium Regulation, Lens Organogenesis And Cataract

Allen Taylor; Ke Liu; Andrea Caceres; Fu Shang; Junyuan Gao; Xiurong Sun; Richard T. Mathias; Paul G. FitzGerald; Yifat Merbl

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4150.

Retina February 2012

Long-Term Effects of Intravitreal Injection of GMP-Grade Bone-Marrow–Derived CD34 + Cells in NOD-SCID Mice with Acute Ischemia-Reperfusion Injury

PDF

Susanna S. Park; Sergio Caballero; Gerhard Bauer; Bradley Shibata; Alan Roth; Paul G. Fitzgerald; Krisztina I. Forward; Ping Zhou; Jeannine McGee; David G. Telander; Maria B. Grant; Jan A. Nolta
TAGS: cd34 antigens, eye, intravitreal injections, mice, reperfusion injury, severe combined immunodeficiency, bone marrow, good manufacturing practice
Invest. Ophthalmol. Vis. Sci.. 2012; 53(2):986-994. https://doi.org/10.1167/iovs.11-8833

Lens September 2011

Further Analysis of the Lens Phenotype in Lim2 -Deficient Mice

PDF

Yanrong Shi; Alicia B. De Maria; Huan Wang; Richard T. Mathias; Paul G. FitzGerald; Steven Bassnett
TAGS: lens (device), lens, crystalline, mice, phenotype, proteins
Invest. Ophthalmol. Vis. Sci.. 2011; 52(10):7332-7339. https://doi.org/10.1167/iovs.11-7724

Lens August 2011

Juvenile Cataract-Associated Mutation of Solute Carrier SLC16A12 Impairs Trafficking of the Protein to the Plasma Membrane

PDF

John J. Castorino; Shannon M. Gallagher-Colombo; Alex V. Levin; Paul G. FitzGerald; Jessica Polishook; Barbara Kloeckener-Gruissem; Eric Ostertag; Nancy J. Philp
TAGS: cataract, cell membrane, child, mutation, proteins, solutes, lens (device), antibodies, lens, crystalline, rats
Invest. Ophthalmol. Vis. Sci.. 2011; 52(9):6774-6784. https://doi.org/10.1167/iovs.10-6579

Includes: Supplemental Content

Lens May 2011

Intermediate Filaments Regulate Tissue Size and Stiffness in the Murine Lens

PDF

Douglas S. Fudge; John V. McCuaig; Shannon Van Stralen; John F. Hess; Huan Wang; Richard T. Mathias; Paul G. FitzGerald
TAGS: lens (device), lens, crystalline, body tissue, intermediate filaments
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3860-3867. https://doi.org/10.1167/iovs.10-6231

ARVO Annual Meeting Abstract April 2011

Juvenile Cataract-associated Mutation Of Solute Carrier Slc16a12 Impairs Trafficking Of The Protein To The Plasma Membrane

Nancy J. Philp; Barbara Kloeckener-Gruissem; Alex V. Levin; Paul G. FitzGerald; John J. Castorino

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3414.

ARVO Annual Meeting Abstract April 2011

Plectin Is Sufficient To Tether Vimentin To The Lens Fiber Cell Membrane

Paul G. FitzGerald; John F. Hess; A S. Menko; Michael L. Robinson; Gerhard Wiche

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1536.

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Involvement of cytoskeletal motor proteins in nuclear reorganization during lens fiber cell differentiation

Using CRISPR mutants to gain insight into the role of the caspase cleavage site in murine filensin

Lamin phosphorylation directs nuclear condensation and nuclear envelope reorganization during lens differentiation

Aged Nrf2-Null Mice Develop All Major Types of Age-Related Cataracts

Age-related cataracts in mice lacking the Nrf2 antioxidant transcription factor

Altered ubiquitin signaling in mammalian lens development causes metabolic and mitochondrial dysfunction leading to cataractogenesis

Characterization of the cornea in the YAP -/+ mouse

Myo/Nog Cells are Present on the Zonules Between the Ciliary Body and Lens

Deletion of GLUT1 in mouse lens epithelium leads to cataract formation

Tropomodulin 1 regulation of actin is required for the formation of large paddle protrusions between mature lens fiber cells

AQP0 AND BEADED FILAMENT PROTEINS ARE CRITICAL FOR OCULAR LENS BIOMECHANICS

Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells

Characterization of an Early-Onset, Autosomal Recessive, Progressive Retinal Degeneration in Bengal Cats

Links Between Ubiquitin Biology, Calcium Regulation, Lens Organogenesis And Cataract

Long-Term Effects of Intravitreal Injection of GMP-Grade Bone-Marrow–Derived CD34 + Cells in NOD-SCID Mice with Acute Ischemia-Reperfusion Injury

Further Analysis of the Lens Phenotype in Lim2 -Deficient Mice

Juvenile Cataract-Associated Mutation of Solute Carrier SLC16A12 Impairs Trafficking of the Protein to the Plasma Membrane

Intermediate Filaments Regulate Tissue Size and Stiffness in the Murine Lens

Juvenile Cataract-associated Mutation Of Solute Carrier Slc16a12 Impairs Trafficking Of The Protein To The Plasma Membrane

Plectin Is Sufficient To Tether Vimentin To The Lens Fiber Cell Membrane

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