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Lecture April 2019

Presbyopia and Glaucoma: Two Diseases, One Pathophysiology? The Friedenwald Lecture

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Paul L. Kaufman; Elke Lütjen Drecoll; Mary Ann Croft
TAGS: glaucoma, visual accommodation, lens, crystalline, presbyopia, eye, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1801-1812. doi: 10.1167/iovs.19-26899

Includes: Supplemental Content

Glaucoma October 2018

Effects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure

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Junkai Tan; Ning Fan; Ningli Wang; BingKai Feng; Ming Yang; Guo Liu; Yun Wang; Xianjun Zhu; Paul L. Kaufman; Iok-Hou Pang; Xuyang Liu
TAGS: actins, injections, lentivirus, trabecular meshwork, eye, intraocular pressure, rats, lentiviral vector
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4937-4944. doi: 10.1167/iovs.18-24978

ARVO Annual Meeting Abstract July 2018

CILIARY MUSCLE AND CILIARY PROCESS’ AREA: AGING CHANGES VERSUS LENS DIMENSIONS AT REST AND DURING ACCOMMODATION

Mary Ann Croft; T Michael Nork; Jared P McDonald; Gregg A Heatley; Elke Lütjen-Drecoll; Paul L Kaufman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1948. doi:

ARVO Annual Meeting Abstract July 2018

ENHANCED AQUEOUS OUTFLOW FACILITY IN HUMAN EYES BY SB772077B, A NEW RHO KINASE INHIBITOR

Srinivasan Senthilkumari; Aswinbalaji Soundararajan; Gowripriya Chidambaranathan; Ramaswamy Krishnadas; B'Ann T Gabelt; Paul L Kaufman; Veerapan Muthukkaruppan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4716. doi:

Glaucoma January 2018

Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork

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Zeynep Aktas; Hongyu Rao; Sarah R. Slauson; B'Ann T. Gabelt; Inna V. Larsen; Rachael T. C. Sheridan; Leonie Herrnberger; Ernst R. Tamm; Paul L. Kaufman; Curtis R. Brandt
TAGS: cercopithecidae, dimethyl sulfoxide, disease vectors, dna, genes, genome, feline immunodeficiency virus, body tissue, trabecular meshwork, toxic effect, multicatalytic endopeptidase complex, spatial vectors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):298-310. doi: 10.1167/iovs.17-22074

Includes: Supplemental Content

Glaucoma August 2017

Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics

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Carla J. Siegfried; Ying-Bo Shui; Baohe Tian; T. Michael Nork; Gregg A. Heatley; Paul L. Kaufman
TAGS: antioxidants, oxygen, cercopithecidae, surgical procedures, operative, vitrectomy, vitreous body, aqueous humor, eye, intraocular pressure, macaca mulatta, macaca
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4003-4014. doi: 10.1167/iovs.17-21890

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Exoenzyme C3 transferaselowered IOP in rats

Xuyang Liu; Junkai Tan; Yun Wang; Ning Fan; Paul L Kaufman; Ningli Wang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1601. doi:

ARVO Annual Meeting Abstract June 2017

ACCOMMODATION & PRESBYOPIA: MOVEMENTS OF THE ACCOMMODATIVE APPARATUS IN THE PRESENCE OF THE IRIS AND LENS

Mary Ann Croft; T Michael Nork; Jared P. McDonald; Gregg A Heatley; Elke Luetjen-Drecoll; Paul L Kaufman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2477. doi:

ARVO Annual Meeting Abstract June 2017

Aqueous humor biomarker of oxidative damage and antioxidant status: Correlations with oxygen and racial differences

Carla J Siegfried; Ying-Bo Shui; Ying Liu; Andrew J W Huang; Paul L Kaufman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4901. doi:

Research Highlight November 2016

Diurnal Fluctuation of Intraocular Pressure

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Paul L. Kaufman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6427-6427. doi: 10.1167/iovs.16-20997

ARVO Annual Meeting Abstract September 2016

Hemiretinal Endodiathermy Axotomy (HEA) In Non-Human Primates: Structural Changes by Spectral Domain Optical Coherence Tomography (sdOCT)

Carol Rasmussen; Alexander Katz; Charlene B Y Kim; Anne K Goulding; Paul L Kaufman; Christopher J Murphy; Yijun Huang; T Michael Nork

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2200. doi:

ARVO Annual Meeting Abstract September 2016

ACCOMMODATIVE APPARATUS: MOVEMENTS IN PHAKIC AND APHAKIC EYES, INTERCONNECTIONS WITH THE VITREOUS AND PRESBYOPIA

Mary Ann Croft; T Michael Nork; Jared McDonald; Gregg A Heatley; Elke Lütjen-Drecoll; Paul L Kaufman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Long-term Efficacy and Safety of Latanoprostene Bunod 0.024% for Intraocular Pressure Lowering in Patients with Open-Angle Glaucoma or Ocular Hypertension: APOLLO and LUNAR Studies

Jason L Vittitow; Jeffrey M Liebmann; Paul L Kaufman; Felipe A Medeiros; Keith R Martin; Robert N Weinreb

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3030. doi:

ARVO Annual Meeting Abstract September 2016

Integrated Efficacy of Latanoprostene Bunod 0.024% vs. Timolol Maleate 0.5% for Intraocular Pressure Lowering in Patients with Open-Angle Glaucoma or Ocular Hypertension: APOLLO and LUNAR Studies

Paul L Kaufman; Jeffrey M Liebmann; Jason L Vittitow; Robert N Weinreb

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3036. doi:

ARVO Annual Meeting Abstract June 2015

Genome Deficient Lentiviral Particles Improve FIV Transduction Efficiency of Trabecular Meshwork

Curtis R Brandt; Hongyu Rao; B'Ann T Gabelt; Zeynep Aktas; Sarah Slauson; Paul L Kaufman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3280. doi:

ARVO Annual Meeting Abstract June 2015

MECHANISM OF ACCOMMODATION: NEW FINDINGS AND THE IMPLICATIONS FOR PRESBYOPIA

Mary Ann Croft; T Michael Nork; Jared McDonald; Gregg A Heatley; Alexander Katz; Paul L Kaufman; Elke Luetjen-Drecoll

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3568. doi:

Glaucoma May 2015

Rat, Mouse, and Primate Models of Chronic Glaucoma Show Sustained Elevation of Extracellular ATP and Altered Purinergic Signaling in the Posterior Eye

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Wennan Lu; HuiLing Hu; Jean Sévigny; B'Ann T. Gabelt; Paul L. Kaufman; Elaine C. Johnson; John C. Morrison; Gulab S. Zode; Val C. Sheffield; Xiulan Zhang; Alan M. Laties; Claire H. Mitchell
TAGS: signal transduction, glaucoma, primates, eye, intraocular pressure, mice, entpd1 gene
Invest. Ophthalmol. Vis. Sci.. 2015; 56(5):3075-3083. doi: 10.1167/iovs.14-15891

Includes: Supplemental Content

Glaucoma April 2015

Viral Vector Effects on Exoenzyme C3 Transferase–Mediated Actin Disruption and on Outflow Facility

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Sarah R. Slauson; Donna M. Peters; Marie K. Schwinn; Paul L. Kaufman; B'Ann T. Gabelt; Curtis R. Brandt
TAGS: actins, viral vector, adenoviruses, transferase, proteins, exoenzymes, spatial vectors
Invest. Ophthalmol. Vis. Sci.. 2015; 56(4):2431-2438. doi: 10.1167/iovs.14-15909

Glaucoma November 2014

Identification of Adult Stem Cells in Schwalbe's Line Region of the Primate Eye

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Barbara M. Braunger; Bahar Ademoglu; Sebastian E. Koschade; Rudolf Fuchshofer; B'Ann T. Gabelt; Julie A. Kiland; Elizabeth A. Hennes-Beann; Kevin G. Brunner; Paul L. Kaufman; Ernst R. Tamm
TAGS: stem cells, adult, bromodeoxyuridine, primates, eye, line of schwalbe
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7499-7507. doi: 10.1167/iovs.14-14872

Clinical Trials September 2014

Latrunculin B Reduces Intraocular Pressure in Human Ocular Hypertension and Primary Open-Angle Glaucoma

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Carol A. Rasmussen; Paul L. Kaufman; Robert Ritch; Reza Haque; R. Kim Brazzell; Jason L. Vittitow
TAGS: open-angle glaucoma, ocular hypertension, placebos, safety, eye, intraocular pressure
Trans. Vis. Sci. Tech.. 2014; 3(5):1. doi: 10.1167/tvst.3.5.1

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Presbyopia and Glaucoma: Two Diseases, One Pathophysiology? The Friedenwald Lecture

Effects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure

CILIARY MUSCLE AND CILIARY PROCESS’ AREA: AGING CHANGES VERSUS LENS DIMENSIONS AT REST AND DURING ACCOMMODATION

ENHANCED AQUEOUS OUTFLOW FACILITY IN HUMAN EYES BY SB772077B, A NEW RHO KINASE INHIBITOR

Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork

Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics

Exoenzyme C3 transferaselowered IOP in rats

ACCOMMODATION & PRESBYOPIA: MOVEMENTS OF THE ACCOMMODATIVE APPARATUS IN THE PRESENCE OF THE IRIS AND LENS

Aqueous humor biomarker of oxidative damage and antioxidant status: Correlations with oxygen and racial differences

Diurnal Fluctuation of Intraocular Pressure

Hemiretinal Endodiathermy Axotomy (HEA) In Non-Human Primates: Structural Changes by Spectral Domain Optical Coherence Tomography (sdOCT)

ACCOMMODATIVE APPARATUS: MOVEMENTS IN PHAKIC AND APHAKIC EYES, INTERCONNECTIONS WITH THE VITREOUS AND PRESBYOPIA

Long-term Efficacy and Safety of Latanoprostene Bunod 0.024% for Intraocular Pressure Lowering in Patients with Open-Angle Glaucoma or Ocular Hypertension: APOLLO and LUNAR Studies

Integrated Efficacy of Latanoprostene Bunod 0.024% vs. Timolol Maleate 0.5% for Intraocular Pressure Lowering in Patients with Open-Angle Glaucoma or Ocular Hypertension: APOLLO and LUNAR Studies

Genome Deficient Lentiviral Particles Improve FIV Transduction Efficiency of Trabecular Meshwork

MECHANISM OF ACCOMMODATION: NEW FINDINGS AND THE IMPLICATIONS FOR PRESBYOPIA

Rat, Mouse, and Primate Models of Chronic Glaucoma Show Sustained Elevation of Extracellular ATP and Altered Purinergic Signaling in the Posterior Eye

Viral Vector Effects on Exoenzyme C3 Transferase–Mediated Actin Disruption and on Outflow Facility

Identification of Adult Stem Cells in Schwalbe's Line Region of the Primate Eye

Latrunculin B Reduces Intraocular Pressure in Human Ocular Hypertension and Primary Open-Angle Glaucoma

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