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Retina November 2020

Genotype Phenotype Correlation and Variability in Microcephaly Associated With Chorioretinopathy or Familial Exudative Vitreoretinopathy

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Maria F. Shurygina; Joseph M. Simonett; Maria A. Parker; Amanda Mitchell; Florin Grigorian; Jacob Lifton; Aaron Nagiel; Alexander A. Shpak; Elena L. Dadali; Irina A. Mishina; Richard G. Weleber; Paul Yang; Mark E. Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):2. doi: https://doi.org/10.1167/iovs.61.13.2

Includes: Supplemental Content

Articles October 2020

A Ketogenic & Low-Protein Diet Slows Retinal Degeneration in rd10 Mice

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Renee C. Ryals; Samuel J. Huang; Dahlia Wafai; Claire Bernert; William Steele; Makayla Six; Shasank Bonthala; Hope Titus; Paul Yang; Melanie Gillingham; Mark E. Pennesi
TAGS: diet, diet, protein-restricted, mice, proteins, retina, retinal degeneration, electroretinography, serum albumin
Trans. Vis. Sci. Tech.. 2020; 9(11):18. doi: https://doi.org/10.1167/tvst.9.11.18

Includes: Multimedia, Supplemental Content

Retina August 2020

Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

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Paul Yang; Rachel Lockard; Hope Titus; Jordan Hiblar; Kyle Weller; Dahlia Wafai; Richard G. Weleber; Robert M. Duvoisin; Catherine W. Morgans; Mark E. Pennesi
TAGS: cyclic gmp, cytotoxicity, mice, photoreceptors, mycophenolate mofetil, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):25. doi: https://doi.org/10.1167/iovs.61.10.25

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Neuroprotective Mechanisms of Dark Rearing on cGMP in rd10 mice

Paul Yang; Hope Titus; Jordan Hiblar; Dahlia Wafai; Robert M Duvoisin; Richard G Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2482. doi:

Review June 2020

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

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Debra A. Thompson; Alessandro Iannaccone; Robin R. Ali; Vadim Y. Arshavsky; Isabelle Audo; James W. B. Bainbridge; Cagri G. Besirli; David G. Birch; Kari E. Branham; Artur V. Cideciyan; Steven P. Daiger; Deniz Dalkara; Jacque L. Duncan; Abigail T. Fahim; John G. Flannery; Roberto Gattegna; John R. Heckenlively; Elise Heon; K. Thiran Jayasundera; Naheed W. Khan; Henry Klassen; Bart P. Leroy; Robert S. Molday; David C. Musch; Mark E. Pennesi; Simon M. Petersen-Jones; Eric A. Pierce; Rajesh C. Rao; Thomas A. Reh; Jose A. Sahel; Dror Sharon; Paul A. Sieving; Enrica Strettoi; Paul Yang; David N. Zacks; The Monaciano Consortium
TAGS: outcome measures, retinal diseases, surrogate endpoints, genetics, vision, natural history, ethics, gene therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):2. doi: https://doi.org/10.1167/tvst.9.7.2

ARVO Annual Meeting Abstract July 2019

An analysis of intraoperative optical coherence tomography findings in subretinal gene therapy surgery

Huber Vasconcelos Junior; Paul Yang; Mark E Pennesi; Brandon J Lujan; Andreas K Lauer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6399. doi:

ARVO Annual Meeting Abstract July 2019

Expanded clinical spectrum of pentosan polysulfate sodium-associated pigmentary maculopathy

Adam Marcus Hanif; Stanford Taylor; Stephen Armenti; Rachel Shah; Austin Igelman; Mark E Pennesi; Thiran Jayasundera; Paul Yang; Thomas S Hwang; Christina J Flaxel; Rahul Khurana; Joshua D Stein; Nieraj Jain

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3245. doi:

ARVO Annual Meeting Abstract July 2019

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice

Paul Yang; Hope Titus; Kyle Weller; Robert Duvoisin; Richard Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):453. doi:

ARVO Annual Meeting Abstract July 2019

Autoimmune retinopathy in two patients with stiff-person syndrome with anti-GAD65 autoantibodies

Mauricio E Vargas; Huber Vasconcelos Junior; Sufang Yang; Grazyna Adamus; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):815. doi:

ARVO Annual Meeting Abstract July 2019

Neuroprotective Mechanisms of Dark Rearing in rd10 mice

Hope Titus; Kyle Weller; Rachel Lockard; Richard Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4887. doi:

Retina March 2019

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy

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Dan Jiang; Renee C. Ryals; Samuel J. Huang; Kyle K. Weller; Hope E. Titus; Bryan M. Robb; Firas W. Saad; Ribal A. Salam; Hytham Hammad; Paul Yang; Daniel L. Marks; Mark E. Pennesi
TAGS: fumarates, mice, microglia, retina, retinal degeneration, retinal diseases, light exposure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1275-1285. doi: https://doi.org/10.1167/iovs.18-24398

Includes: Supplemental Content

Retina December 2018

Prospective Evaluation of Patients With X-Linked Retinoschisis During 18 Months

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Mark E. Pennesi; David G. Birch; K. Thiran Jayasundera; Maria Parker; Ou Tan; Rabia Gurses-Ozden; Carrie Reichley; Kathleen N. Beasley; Paul Yang; Richard G. Weleber; Lea D. Bennett; John R. Heckenlively; Kalyani Kothapalli; Jeffrey D. Chulay; for the XLRS-001 Study Group
TAGS: cysts, electroretinography, eye, perimetry, vision, visual acuity, volume, x-linked retinoschisis, contrast sensitivity, cutaneous collagenous vasculopathy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5941-5956. doi: https://doi.org/10.1167/iovs.18-24565

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Intravitreal Anti-VEGF Therapy for Choroidal Neovascularization-Associated with Best Vitelliform Macular Dystrophy

Florin Grigorian; Huber Martins Vasconcelos; Steven T Bailey; Brandon J Lujan; J. Peter Campbell; Phoebe Lin; Richard G Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3145. doi:

ARVO Annual Meeting Abstract July 2018

Projection-Resolved Optical Coherence Tomography Angiography of Retinal Plexusess in Retinitis Pigmentosa and Usher Syndrome Type 1

Ahmed M Hagag; JIE WANG; Terry Wood; Joseph Michael Simonett; Gareth Harman; Kevin Liu; David Huang; Richard G Weleber; Mark E Pennesi; Paul Yang; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2842. doi:

ARVO Annual Meeting Abstract July 2018

Test-Retest Variability of Functional and Structural Parameters in patients with Usher Syndrome Type-1B (USH1B)

Maria A Parker; Andreas Lauer; Tim Stout; Mark E Pennesi; Paul Yang; David J Wilson; Dongseok Choi; Laura R Erker; Brandon J Lujan; Ou Tan; Pierre-Olivier Barale; Caroline Cohen; Saddek Mohand-Said; Isabelle S Audo; Jose A. Sahel; Richard G Weleber

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3896. doi:

ARVO Annual Meeting Abstract July 2018

Dark-rearing reduces degeneration and alters the characteristics of cGMP dysregulation in rd10 mice

Hope Titus; Kyle K. Weller; Jenny Li; Richard G Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1001. doi:

ARVO Annual Meeting Abstract July 2018

Next Generation Sequencing in Pigmented Paravenous Retinochoroidal Atrophy

Huber Martins Vasconcelos; Amanda Mitchell; Florin Gregorian; Pei-Wen Chiang; Rui Chen; Yumei Li; Richard G Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2339. doi:

ARVO Annual Meeting Abstract July 2018

Monomethyl fumarate protects the retina in a mouse model of light-induced retinal degeneration

Dan Jiang; Renee C. Ryals; Samuel J. Huang; Kyle K. Weller; Hope E. Titus; Bryan M. Robb; Firas W. Saad; Ribal A. Salam; Paul Yang; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2486. doi:

ARVO Annual Meeting Abstract July 2018

Early Treatment with Mycophenolate Mofetil Reduces Retinal Degeneration and cGMP Dysregulation in rd10 and rd1 mice

Paul Yang; Rachel Lockard; Hope E. Titus; Kyle K. Weller; Aaron S Coyner; Robert M Duvoisin; Richard G Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2503. doi:

Retina January 2018

The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection

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Cristy A. Ku; Renee C. Ryals; Dan Jiang; Aaron S. Coyner; Kyle K. Weller; Wrik Sinha; Bryan M. Robb; Paul Yang; Mark E. Pennesi
TAGS: mitogen-activated protein kinases, neuroprotection, phosphorylation, proteins, extracellular matrix-cell signaling, western blotting, mice, gene expression, cyclic amp-responsive dna-binding protein, serotonin
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):462-471. doi: https://doi.org/10.1167/iovs.17-23159

Includes: Supplemental Content

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Genotype Phenotype Correlation and Variability in Microcephaly Associated With Chorioretinopathy or Familial Exudative Vitreoretinopathy

A Ketogenic & Low-Protein Diet Slows Retinal Degeneration in rd10 Mice

Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

Neuroprotective Mechanisms of Dark Rearing on cGMP in rd10 mice

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

An analysis of intraoperative optical coherence tomography findings in subretinal gene therapy surgery

Expanded clinical spectrum of pentosan polysulfate sodium-associated pigmentary maculopathy

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice

Autoimmune retinopathy in two patients with stiff-person syndrome with anti-GAD65 autoantibodies

Neuroprotective Mechanisms of Dark Rearing in rd10 mice

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy

Prospective Evaluation of Patients With X-Linked Retinoschisis During 18 Months

Intravitreal Anti-VEGF Therapy for Choroidal Neovascularization-Associated with Best Vitelliform Macular Dystrophy

Projection-Resolved Optical Coherence Tomography Angiography of Retinal Plexusess in Retinitis Pigmentosa and Usher Syndrome Type 1

Test-Retest Variability of Functional and Structural Parameters in patients with Usher Syndrome Type-1B (USH1B)

Dark-rearing reduces degeneration and alters the characteristics of cGMP dysregulation in rd10 mice

Next Generation Sequencing in Pigmented Paravenous Retinochoroidal Atrophy

Monomethyl fumarate protects the retina in a mouse model of light-induced retinal degeneration

Early Treatment with Mycophenolate Mofetil Reduces Retinal Degeneration and cGMP Dysregulation in rd10 and rd1 mice

The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection

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