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ARVO Annual Meeting Abstract June 2023

Controlled Release of Adeno-Associated Viruses (AAVs) Using Hydrogel Implants Improve GFP Expression and Reduce Anti-Drug Antibody (ADA) Titers and Inflammation in Rabbits

Meryem Pehlivaner; Steven Lu; Nelson Bello; Rabia Gurses Ozden; Rami El Hayek; Charles D Blizzard; Peter K Jarrett

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):802.

ARVO Annual Meeting Abstract June 2023

Preclinical Safety and Tolerability of Repeated Intracameral Travoprost Implant (OTX-TIC) Administrations

Chintan Patel; Charles D Blizzard; Jeremy Hartman; Sean Serell; Kevin Yeh; Andrew Vanslette; Peter K Jarrett; Rabia Gurses Ozden

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4299.

ARVO Annual Meeting Abstract June 2022

A 6-Month GLP Toxicology Study of a Novel Hydrogel-based, Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates

Chintan Patel; Erica Kahn; Megan Priem; Joe Iacona; Andrew Vanslette; Erik Wong; Charles D Blizzard; Peter K Jarrett; Michael Goldstein; Rabia Gurses-Ozden

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):298 – F0101.

ARVO Annual Meeting Abstract June 2022

A Safety and Pharmacokinetic Study of a Novel Hydrogel-based Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates

Erica Kahn; Chintan Patel; Megan Priem; Joe Iacona; Andrew Vanslette; Erik Wong; Charles D Blizzard; Peter K Jarrett; Michael Goldstein; Rabia Gurses-Ozden

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):297 – F0100.

ARVO Annual Meeting Abstract June 2022

Safety and Pharmacodynamic Assessment of Repeated Intracameral Travoprost Implant Administration in Beagle Dogs

Charles D Blizzard; Chintan Patel; Jeremy Hartman; Sean Serell; Kevin Yeh; Andrew Vanslette; Peter K Jarrett; Michael Goldstein; Rabia Gurses-Ozden

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2852 – A0375.

ARVO Annual Meeting Abstract June 2022

Pharmacokinetics of a Hydrogel-based Nepafenac Intracanalicular Insert in Canines

Oktay Uzun; Ankita Desai; Sanjani Ray; Chintan Patel; Charles D Blizzard; Peter K Jarrett; Michael Goldstein

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):447.

ARVO Annual Meeting Abstract June 2022

Pharmacokinetics of a Hydrogel-based Besifloxacin Intracanalicular Insert in Canines

Megan Priem; Ankita Desai; Chintan Patel; Charles D Blizzard; Peter K Jarrett; Michael Goldstein

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2128 – F0144.

ARVO Annual Meeting Abstract July 2019

Pharmacodynamic Effect and Corneal Wound Healing of OTX-BPI, a Sustained Release Bupivacaine Intracanalicular Hydrogel Insert in Beagle Dogs

Rami F Elhayek; Jacob Dexter; Nelson Bello; Erica Kahn; Stephanie Manning; Charles D Blizzard; Arthur Driscoll; Jamie L Metzinger; Michael H Goldstein; Peter K Jarrett

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2099.

ARVO Annual Meeting Abstract July 2019

Efficacy & Tolerability of OTX-TKI, a Sustained Hydrogel Delivery System for a Tyrosine Kinase Inhibitor, in a VEGF Induced Retinal Leakage Model: 1 Year Results

Peter K Jarrett; Rami F Elhayek; Erica Kahn; Stephen Takach; Jamie L Metzinger; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):372.

ARVO Annual Meeting Abstract July 2018

Effectiveness of Sustained Release TKI Hydrogel Combined with Bevacizumab in a VEGF Induced Retinal Leakage Model Through 12 Months

Rami F Elhayek; Tim Jarrett; Zachary Lattrell; Erica Kahn; Stephen Takach; Jamie Lynne Metzinger; Michael H Goldstein; Peter K Jarrett; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):245.

ARVO Annual Meeting Abstract July 2018

Efficacy & Tolerability of OTX-TKI, a Sustained Hydrogel Delivery System for a Tyrosine Kinase Inhibitor, in a VEGF Induced Retinal Leakage Model Through 12 Months

Peter K Jarrett; Rami F Elhayek; Tim Jarrett; Zachary Lattrell; Erica Kahn; Stephen Takach; Jamie Lynne Metzinger; Michael H Goldstein; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3465.

ARVO Annual Meeting Abstract June 2017

Tolerability of a Shape Changing Intravitreal Hydrogel Depot

Arthur Driscoll; Charles D Blizzard; Jonathan H Talamo; Peter K Jarrett; Rami F Elhayek; Tim Jarrett; Zach Lattrell; Michael McGrath; Stephen Takach; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1980.

ARVO Annual Meeting Abstract June 2017

Tolerability of a 6 month Sustained Hydrogel Delivery System for Tyrosine Kinase Inhibitors in Dutch Belted Rabbits

Peter K Jarrett; Rami F Elhayek; Tim Jarrett; Zach Lattrell; Michael McGrath; Stephen Takach; Jonathan H. Talamo; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1956.

ARVO Annual Meeting Abstract June 2017

Pharmacokinetics of a 6 month Sustained Hydrogel Delivery System for Tyrosine Kinase Inhibitors in Dutch Belted Rabbits

Tim Jarrett; Rami F Elhayek; Zach Lattrell; Michael McGrath; Stephen Takach; Peter K Jarrett; Jonathan H. Talamo; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1984.

ARVO Annual Meeting Abstract June 2017

Efficacy of a 6 month Sustained Hydrogel Delivery System for Tyrosine Kinase Inhibitors in a VEGF Induced Retinal Leakage Model

Rami F Elhayek; Tim Jarrett; Zach Lattrell; Stephen Takach; Peter K Jarrett; Michael McGrath; Jonathan H Talamo; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1968.

ARVO Annual Meeting Abstract September 2016

Tolerability of In Situ Forming Intravitreal Hydrogel Depots for Anti-VEGF Sustained Release in a Rabbit Model

Charles D Blizzard; Courtney Rosales; Timothy Jarrett; Rami F Elhayek; sarah guedez; Andrew Vanslette; Peter K Jarrett; Arthur Driscoll; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1120.

ARVO Annual Meeting Abstract September 2016

Sustained Delivery of Cyclosporine from an Intracanalicular Depot in a Canine Model

Daniel Lee Smoot; Rami F Elhayek; Zachary Lattrell; Mike McGrath; Timothy Jarrett; Courtney Rosales; Peter K Jarrett; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):423.

ARVO Annual Meeting Abstract June 2015

Tolerability of Intravitreal Hydrogel Depots for Anti-VEGF Sustained Release in a Rabbit Model

Peter K Jarrett; Rami F Elhayek; Sarah Guedez; Courtney Rosales; Timothy S. Jarrett; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1496.

ARVO Annual Meeting Abstract June 2015

Preservation of Bevacizumab Anti-VEGF Bioactivity and Monomeric Structure During Processing into a Sustained Release Bevacizumab Intravitreal Depot

sarah guedez; Charles D Blizzard; allison wyand; Jennifer Wittbold; Rami F Elhayek; Andrew Vanslette; Peter K Jarrett; Arthur Driscoll; Amar Sawhney

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1500.

ARVO Annual Meeting Abstract June 2015

Pharmacokinetics of Bevacizumab Sustained Release from Intravitreal Hydrogel Depots in a Rabbit Model Compared to a single Avastin Dose

Rami F Elhayek; Peter K Jarrett; Amar Sawhney; Arthur Driscoll; Timothy S. Jarrett; Courtney Rosales; Andrew Vanslette; Charles D Blizzard; sarah guedez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1522.

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