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Articles March 2021

Reliability of Retinal Pathology Quantification in Age-Related Macular Degeneration: Implications for Clinical Trials and Machine Learning Applications

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Philipp L. Müller; Bart Liefers; Tim Treis; Filipa Gomes Rodrigues; Abraham Olvera-Barrios; Bobby Paul; Narendra Dhingra; Andrew Lotery; Clare Bailey; Paul Taylor; Clarisa I. Sánchez; Adnan Tufail
TAGS: age-related macular degeneration, machine learning, pathology, reliability, drusen, diagnostic imaging
Trans. Vis. Sci. Tech.. 2021; 10(3):4. doi: https://doi.org/10.1167/tvst.10.3.4

Includes: Supplemental Content

Articles December 2019

Functional Relevance and Structural Correlates of Near Infrared and Short Wavelength Fundus Autofluorescence Imaging in ABCA4 -Related Retinopathy

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Philipp L. Müller; Johannes Birtel; Philipp Herrmann; Frank G. Holz; Peter Charbel Issa; Martin Gliem
TAGS: fundus autofluorescence imaging, retinal diseases, eye, diagnostic imaging
Trans. Vis. Sci. Tech.. 2019; 8(6):46. doi: https://doi.org/10.1167/tvst.8.6.46

Includes: Supplemental Content

Retina August 2019

A Specific Macula-Predominant Retinal Phenotype Is Associated With the CDHR1 Variant c.783G>A, a Silent Mutation Leading to In-Frame Exon Skipping

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Peter Charbel Issa; Martin Gliem; Imran H. Yusuf; Johannes Birtel; Philipp L. Müller; Elisabeth Mangold; Susan M. Downes; Robert E. MacLaren; Christian Betz; Hanno J. Bolz
TAGS: exons, macula densa, macula lutea, mutation, phenotype, retinal diseases, silent mutations, homozygote
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3388-3397. doi: https://doi.org/10.1167/iovs.18-26415

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging January 2019

Spectrally Resolved Fundus Autofluorescence in ABCA4 -Related Retinopathy

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Chantal Dysli; Philipp L. Müller; Johannes Birtel; Frank G. Holz; Philipp Herrmann
TAGS: fundus autofluorescence imaging, retinal diseases, diagnostic imaging, color
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):274-281. doi: https://doi.org/10.1167/iovs.18-25755

Articles October 2018

Comparison of Green Versus Blue Fundus Autofluorescence in ABCA4 -Related Retinopathy

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Philipp L. Müller; Maximilian Pfau; Matthias M. Mauschitz; Philipp T. Möller; Johannes Birtel; Petrus Chang; Martin Gliem; Steffen Schmitz-Valckenberg; Monika Fleckenstein; Frank G. Holz; Philipp Herrmann
TAGS: atrophy, fundus autofluorescence imaging, global assessment of functioning, retinal diseases, diagnostic imaging, eye, shape
Trans. Vis. Sci. Tech.. 2018; 7(5):13. doi: https://doi.org/10.1167/tvst.7.5.13

Includes: Supplemental Content

Special Issue August 2018

Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study

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Philipp L. Müller; Maximilian Pfau; Philipp T. Möller; Jennifer Nadal; Matthias Schmid; Moritz Lindner; Luis de Sisternes; Heidi Stöhr; Bernhard H. F. Weber; Christine Neuhaus; Philipp Herrmann; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein
TAGS: age-related macular degeneration, angiogram, atrophy, fluid flow, stargardt's disease, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD122-AMD131. doi: https://doi.org/10.1167/iovs.18-23819

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

The retinal phenotype associated with the frequent, synonymous c.783G>A mutation in CDHR1

Imran H. Yusuf; Martin Gliem; Johannes Birtel; Philipp L Muller; Elisabeth Mangold; Hanno Bolz; Peter Charbel Issa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3146. doi:

Retina December 2017

Quantitative Fundus Autofluorescence in Pseudoxanthoma Elasticum

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Martin Gliem; Philipp L. Müller; Johannes Birtel; Myra B. McGuinness; Robert P. Finger; Philipp Herrmann; Doris Hendig; Frank G. Holz; Peter Charbel Issa
TAGS: bruch's basal membrane, calcification, fundus autofluorescence imaging, pseudoxanthoma elasticum, lipofuscin, atrophy
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6159-6165. doi: https://doi.org/10.1167/iovs.17-22007

Retina August 2017

Novel Insights Into the Phenotypical Spectrum of KIF11 -Associated Retinopathy, Including a New Form of Retinal Ciliopathy

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Johannes Birtel; Martin Gliem; Elisabeth Mangold; Lars Tebbe; Isabel Spier; Philipp L. Müller; Frank G. Holz; Christine Neuhaus; Uwe Wolfrum; Hanno J. Bolz; Peter Charbel Issa
TAGS: ciliopathies, retinal diseases, phenotype
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):3950-3959. doi: https://doi.org/10.1167/iovs.17-21679

Includes: Supplemental Content

Special Issue July 2017

Effective Dynamic Range and Retest Reliability of Dark-Adapted Two-Color Fundus-Controlled Perimetry in Patients With Macular Diseases

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Maximilian Pfau; Moritz Lindner; Philipp L. Müller; Johannes Birtel; Robert P. Finger; Wolf M. Harmening; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg
TAGS: color, dynamic range, macular disorders, perimetry, reliability
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO158-BIO167. doi: https://doi.org/10.1167/iovs.17-21454

Includes: Supplemental Content

Retina June 2016

Frequency, Phenotypic Characteristics and Progression of Atrophy Associated With a Diseased Bruch's Membrane in Pseudoxanthoma Elasticum

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Martin Gliem; Philipp L. Müller; Johannes Birtel; Doris Hendig; Frank G. Holz; Peter Charbel Issa
TAGS: atrophy, bruch's basal membrane, phenotype, pseudoxanthoma elasticum
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3323-3330. doi: https://doi.org/10.1167/iovs.16-19388

Includes: Supplemental Content

Retina March 2016

Perception of Haidinger Brushes in Macular Disease Depends on Macular Pigment Density and Visual Acuity

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Philipp L. Müller; Simone Müller; Martin Gliem; Kristina Küpper; Frank G. Holz; Wolf M. Harmening; Peter Charbel Issa
TAGS: macular disorders, perception, visual acuity, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1448-1456. doi: https://doi.org/10.1167/iovs.15-19004

Includes: Supplemental Content

Review January 2016

M-sequences in ophthalmic electrophysiology

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Philipp L. Müller; Thomas Meigen
TAGS: electrophysiology, eye, medical history, waveforms
Journal of Vision. 2016; 16(1):15. doi: https://doi.org/10.1167/16.1.15

Includes: Multimedia, Supplemental Content

Retina December 2015

Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study

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Philipp L. Müller; Martin Gliem; Elisabeth Mangold; Hanno J. Bolz; Robert P. Finger; Myra McGuinness; Christian Betz; Zhichun Jiang; Bernhard H. F. Weber; Robert E. MacLaren; Frank G. Holz; Roxana A. Radu; Peter Charbel Issa
TAGS: autofluorescence, mutation, phenotype, retinal diseases, mice
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8179-8186. doi: https://doi.org/10.1167/iovs.15-17629

Includes: Supplemental Content

Retina December 2015

Disease Expression in Autosomal Recessive Retinal Dystrophy Associated With Mutations in the DRAM2 Gene

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Panagiotis I. Sergouniotis; Martin McKibbin; Anthony G. Robson; Hanno J. Bolz; Elfride De Baere; Philipp L. Müller; Raoul Heller; Mohammed E. El-Asrag; Kristof Van Schil; Vincent Plagnol; Carmel Toomes; UK Inherited Retinal Disease Consortium; Manir Ali; Graham E. Holder; Peter Charbel Issa; Bart P. Leroy; Chris F. Inglehearn; Andrew R. Webster
TAGS: autosomal recessive inheritance, genes, mutation, retinal diseases, retinal dystrophies
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8083-8090. doi: https://doi.org/10.1167/iovs.15-17604

Includes: Supplemental Content

Retina April 2015

Sorsby Fundus Dystrophy: Novel Mutations, Novel Phenotypic Characteristics, and Treatment Outcomes

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Martin Gliem; Philipp L. Müller; Elisabeth Mangold; Frank G. Holz; Hanno J. Bolz; Heidi Stöhr; Bernhard H. F. Weber; Peter Charbel Issa
TAGS: atrophy, choroidal neovascularization, family, mutation, phenotype, treatment outcome, drusen
Invest. Ophthalmol. Vis. Sci.. 2015; 56(4):2664-2676. doi: https://doi.org/10.1167/iovs.14-15733

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Functional relevance of autofluorescence patterns in Stargardt disease

Philipp Lothar Müller; Martin Gliem; Frank G Holz; Peter Charbel Issa

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5014. doi:

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Reliability of Retinal Pathology Quantification in Age-Related Macular Degeneration: Implications for Clinical Trials and Machine Learning Applications

Functional Relevance and Structural Correlates of Near Infrared and Short Wavelength Fundus Autofluorescence Imaging in ABCA4 -Related Retinopathy

A Specific Macula-Predominant Retinal Phenotype Is Associated With the CDHR1 Variant c.783G>A, a Silent Mutation Leading to In-Frame Exon Skipping

Spectrally Resolved Fundus Autofluorescence in ABCA4 -Related Retinopathy

Comparison of Green Versus Blue Fundus Autofluorescence in ABCA4 -Related Retinopathy

Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study

The retinal phenotype associated with the frequent, synonymous c.783G>A mutation in CDHR1

Quantitative Fundus Autofluorescence in Pseudoxanthoma Elasticum

Novel Insights Into the Phenotypical Spectrum of KIF11 -Associated Retinopathy, Including a New Form of Retinal Ciliopathy

Effective Dynamic Range and Retest Reliability of Dark-Adapted Two-Color Fundus-Controlled Perimetry in Patients With Macular Diseases

Frequency, Phenotypic Characteristics and Progression of Atrophy Associated With a Diseased Bruch's Membrane in Pseudoxanthoma Elasticum

Perception of Haidinger Brushes in Macular Disease Depends on Macular Pigment Density and Visual Acuity

M-sequences in ophthalmic electrophysiology

Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study

Disease Expression in Autosomal Recessive Retinal Dystrophy Associated With Mutations in the DRAM2 Gene

Sorsby Fundus Dystrophy: Novel Mutations, Novel Phenotypic Characteristics, and Treatment Outcomes

Functional relevance of autofluorescence patterns in Stargardt disease

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