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Journal Articles (8)
Meeting Abstract (6)

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Investigative Ophthalmology & Visual Science (14)

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ARVO Annual Meeting Abstract (6)
Anatomy and Pathology/Oncology (6)
Biochemistry and Molecular Biology (1)
Review (1)

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Eye Anatomy and Disorders (8)
Oncology (8)
Genetics (5)
Biochemistry and Molecular Biology (1)
Immunology and Microbiology (1)

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intraocular melanoma (8)
neoplasms (8)
cell lines (4)
epigenetics (3)
genes (3)
methylation (3)
neoplasm metastasis (3)
cohort studies (2)
prognostic factors (2)
antigens (1)

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Showing 1 – 14 of 14

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Review December 2023

PRAME Expression: A Target for Cancer Immunotherapy and a Prognostic Factor in Uveal Melanoma

PDF

Maria Chiara Gelmi; Gulçin Gezgin; Pieter A. van der Velden; Gregorius P. M. Luyten; Sietse J. Luk; Mirjam H. M. Heemskerk; Martine J. Jager
TAGS: cancer, cancer immunotherapy, cohort studies, intraocular melanoma, neoplasms, prognostic factors, t-lymphocytes, neoplasm metastasis, antigens, the cancer genome atlas project
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):36. https://doi.org/10.1167/iovs.64.15.36

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

MITF: a progression marker in uveal melanoma

Maria Gelmi; Marina Marinkovic; T. H. Khanh Vu; Pieter A. van der Velden; Gregorius P. M. Luyten; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2353 – A0022.

Anatomy and Pathology/Oncology March 2020

Prognostic Factors Five Years After Enucleation for Uveal Melanoma

PDF

Mehmet Dogrusöz; Niels J. Brouwer; Stefan J. R. de Geus; Long V. Ly; Stefan Böhringer; Sjoerd G. van Duinen; Wilma G. M. Kroes; Pieter A. van der Velden; Geert W. Haasnoot; Marina Marinkovic; Gregorius P. M. Luyten; Tero T. Kivelä; Martine J. Jager
TAGS: cellular enucleation, enucleation procedure, intraocular melanoma, neoplasms, prognostic factors, neoplasm metastasis, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):31. https://doi.org/10.1167/iovs.61.3.31

ARVO Annual Meeting Abstract June 2017

Differential expression of DNA repair genes in prognostically-good and bad Uveal Melanoma

Mehmet Dogrusoz; Andrea Ruschel Trasel; Sake I. van Pelt; Sjoerd G. van Duinen; Pieter A. van der Velden; Gregorius P M Luyten; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3963.

ARVO Annual Meeting Abstract September 2016

Expression of PD-L1 and PD-1 in conjunctival melanoma

Jinfeng Cao; Kate Richards; Ekaterina S. Jordanova; Marina Marinkovic; Daan Hurkmans; Sjoerd G. van Duinen; Pieter A. van der Velden; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2404.

ARVO Annual Meeting Abstract September 2016

PRAME: a potential target for immunotherapy in uveal melanoma

Gülçin Gezgin; Sietse J. Luk; Jinfeng Cao; Mehmet Dogrusoz; Danielle Krijgsman; Pieter A. van der Velden; Gregorius P. M. Luyten; J.William Harbour; Ekaterina S. Jordanova; Mirjam H. M. Heemskerk; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

Loss of BAP1 expression is associated with increased angiogenesis in uveal melanoma

Gülçin Gezgin; Inge H.G. Bronkhorst; T Huibertus Van Essen; Sake van Pelt; Robert M. Verdijk; Pieter A. van der Velden; Gregorius P M Luyten; Thorbald van Hall; Sjoerd H van der Burg; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5323.

Anatomy and Pathology/Oncology March 2015

Skewed Expression of the Genes Encoding Epigenetic Modifiers in High-Risk Uveal Melanoma

PDF

Naoimh Herlihy; Mehmet Dogrusöz; T. Huibertus van Essen; J. William Harbour; Pieter A. van der Velden; Marja C. J. A. van Eggermond; Geert W. Haasnoot; Peter J. van den Elsen; Martine J. Jager
TAGS: epigenetics, genes, intraocular melanoma, neoplasms, methylation
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1447-1458. https://doi.org/10.1167/iovs.14-15250

Includes: Supplemental Content

Biochemistry and Molecular Biology October 2014

Modeling of Human Uveal Melanoma in Zebrafish Xenograft Embryos

PDF

Wietske van der Ent; Claudia Burrello; Amina F. A. S. Teunisse; Bruce R. Ksander; Pieter A. van der Velden; Martine J. Jager; Aart G. Jochemsen; B. Ewa Snaar-Jagalska
TAGS: cell lines, dasatinib, embryo, intraocular melanoma, transplantation, heterologous, zebrafish, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6612-6622. https://doi.org/10.1167/iovs.14-15202

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Pre-clinical analysis of Crizotinib in MAPK independent uveal melanoma metastases

Pieter van der Velden; Mark de Lange; Mieke Versluis; Gregorius Luyten; Martine Jager; Leiden uveal melanoma group

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4207.

Anatomy and Pathology/Oncology May 2010

Regulation of VEGF-A in Uveal Melanoma

PDF

Mariam el Filali; Guy S. O. A. Missotten; Willem Maat; Long V. Ly; Gregorius P. M. Luyten; Pieter A. van der Velden; Martine J. Jager
TAGS: vascular endothelial growth factor a, intraocular melanoma, hypoxia, neoplasms, cell lines
Invest. Ophthalmol. Vis. Sci.. 2010; 51(5):2329-2337. https://doi.org/10.1167/iovs.09-4739

Anatomy and Pathology/Oncology April 2008

Epigenetic Regulation Identifies RASEF as a Tumor-Suppressor Gene in Uveal Melanoma

PDF

Willem Maat; Sigrid H. W. Beiboer; Martine J. Jager; Gré P. M. Luyten; Nelleke A. Gruis; Pieter A. van der Velden
TAGS: genes, intraocular melanoma, tumor suppressor genes, methylation, epigenetics, neoplasms, regulation
Invest. Ophthalmol. Vis. Sci.. 2008; 49(4):1291-1298. https://doi.org/10.1167/iovs.07-1135

Anatomy and Pathology/Oncology January 2008

Pyrophosphorolysis Detects B-RAF Mutations in Primary Uveal Melanoma

PDF

Willem Maat; Emine Kilic; Gré P. M. Luyten; Annelies de Klein; Martine J. Jager; Nelleke A. Gruis; Pieter A. Van der Velden
TAGS: intraocular melanoma, mutation, cell lines, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2008; 49(1):23-27. https://doi.org/10.1167/iovs.07-0722

Anatomy and Pathology/Oncology February 2007

Epigenetic Inactivation of RASSF1a in Uveal Melanoma

PDF

Willem Maat; Pieter A. van der Velden; Coby Out-Luiting; Maria Plug; Anita Dirks-Mulder; Martine J. Jager; Nelleke A. Gruis
TAGS: epigenetics, intraocular melanoma, methylation, neoplasms, cell lines, dna, neoplasm metastasis
Invest. Ophthalmol. Vis. Sci.. 2007; 48(2):486-490. https://doi.org/10.1167/iovs.06-0781

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