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Retina August 2019

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

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Wen-Tao Deng; Jie Li; Ping Zhu; Beau Freedman; W. Clay Smith; Wolfgang Baehr; William W. Hauswirth
TAGS: gene therapy, mice, retinal cone, opsin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3644-3651. doi: 10.1167/iovs.19-27079

ARVO Annual Meeting Abstract July 2019

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Wen-Tao Deng; Jie Li; Ping Zhu; Wolfgang Baehr; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3419. doi:

ARVO Annual Meeting Abstract July 2019

AIBP suppresses choroidal neovascularization (CNV) by enhancing cholesterol efflux

Yingbin Fu; Mackenzie Parker; Ling-Ping Zhu; Qing Yan; Nduka Enemchukwu; Jun-dae Kim; Longhou Fang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3272. doi:

ARVO Annual Meeting Abstract July 2019

Functional Consequences and Cellular Distribution of C1QTNF5 Mutants in Murine Retinal Pigment Epithelium

Astra Dinculescu; Lei Xu; Susan N Bolch; Frank M Dyka; Ping Zhu; Hugh McDowell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4899. doi:

ARVO Annual Meeting Abstract July 2018

A Novel Hypoxia-Regulated And Cell -Specific Gene Therapy Elicits Reduced Choroidal Neovascularization

Manas Ranjan Biswal; Howard M Prentice; George W Smith; Ping Zhu; Tong Yao; C Kathleen Dorey; Alfred S Lewin; Janet C Blanks

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3965. doi:

ARVO Annual Meeting Abstract June 2017

Genetically modified probiotics for oral delivery of Angiotensin-(1-7) confers protection against diabetic complications

Qiuhong Li; Zhibing Liang; Kang Xu; Tao Du; Ping Zhu; Tuhina Prasad; Shenquan Liao; Manoj Kulkarni; Amrisha Verma; Mohan Raizada

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4049. doi:

ARVO Annual Meeting Abstract June 2017

Co-expression of human L- or M-opsin restores M-Cone Function in the Opn1mw Knock-out mouse, a model for blue cone monochromacy (BCM)

Wentao Deng; Ji-Jing Pang; Jie Li; Ping Zhu; Wolfgang Baehr; W. Clay Smith; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4477. doi:

ARVO Annual Meeting Abstract June 2017

Restoration of M-cone function in an S-cone only mouse model of human blue cone monochromacy by AAV-mediated expression of human L- or M-opsin

Ji-Jing Pang; Wentao Deng; Yuxin Zhang; Jie Li; Ping Zhu; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4478. doi:

ARVO Annual Meeting Abstract June 2017

Oral delivery of Angiotensin-(1-7) bioencapsulated in plant cells protect against diabetes-induced retinopathy and other complications

Amrisha Verma; Kang Xu; Tao Du; Manoj Kulkarni; Ping Zhu; Tuhina Prasad; Henry Daniell; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5213. doi:

Biochemistry and Molecular Biology February 2017

Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD

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Manas R. Biswal; Pingyang Han; Ping Zhu; Zhaoyang Wang; Hong Li; Cristhian J. Ildefonso; Alfred S. Lewin
TAGS: antioxidants, oxidative stress, gene therapy, disease vectors, electroretinography, injection of therapeutic agent, photoreceptors, eye, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1237-1245. doi: 10.1167/iovs.16-21272

Includes: Supplemental Content

Physiology and Pharmacology December 2016

Beneficial Effects of Combined AT 1 Receptor/Neprilysin Inhibition (ARNI) Versus AT 1 Receptor Blockade Alone in the Diabetic Eye

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Tuhina Prasad; Lodi C. W. Roksnoer; Ping Zhu; Amrisha Verma; Yiming Li; Wendy W. Batenburg; René de Vries; A. H. Jan Danser; Qiuhong Li
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, neprilysin, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6722-6730. doi: 10.1167/iovs.16-20289

ARVO Annual Meeting Abstract September 2016

Reduced Optic Atrophy 1 (OPA1) gene expression in diabetic retina- implication of mitochondrial dynamics in pathogenesis of diabetic retinopathy.

Amrisha Verma; Ping Zhu; Tuhina Prasad; Zhibing Liang; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5446. doi:

ARVO Annual Meeting Abstract September 2016

Expression of repressor element 1-silencing transcription factor (REST) gene in rodent and human retina- implication in AMD

Tuhina Prasad; Amrisha Verma; Ping Zhu; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5801. doi:

ARVO Annual Meeting Abstract September 2016

Early Sub-retinal Delivery of AAV1- Sod2 Protects the Retina in a Mouse Model of Progressive Retinal Degeneration.

Manas Ranjan Biswal; Cristhian J Ildefonso; Bradley D Justis; Hong Li; Pingyang Han; Ping Zhu; Lindsey Elizabeth Buz; Chulbul M Ahmed; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6548. doi:

ARVO Annual Meeting Abstract September 2016

Gene therapy in the Opn1mw Knock-out mouse, a model for blue cone monochromacy, leads to long-term M-cone restoration

Ji-Jing Pang; Yuxin Zhang; Ping Zhu; Wen-Tao Deng; Jie Li; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1166. doi:

ARVO Annual Meeting Abstract September 2016

Long term restoration of cone function following AAV-mediated gene therapy in CNGA3 -/- Nrl -/- Mice

Yuxin Zhang; Wei Du; Ping Zhu; Jie Li; Wen-Tao Deng; Chen Zhao; William Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1175. doi:

ARVO Annual Meeting Abstract September 2016

Beneficial effects of combined AT1 receptor/neprilysin inhibition (ARNI) versus AT1 receptor blockade alone in the diabetic eye

Qiuhong Li; Lodi Roksnoer; Tuhina Prasad; Ping Zhu; Amrisha Verma; Wendy Batenburg; Rene de Vries; A.H. Jan Danser

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2712. doi:

ARVO Annual Meeting Abstract June 2015

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Opn1mw KO Mice

Ji-Jing Pang; Wei Du; Ping Zhu; Yuxin Zhang; Jinfeng Sun; Wolfgang Baehr; Sanford L Boye; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1092. doi:

ARVO Annual Meeting Abstract June 2015

Delaying Retinal Degeneration in a Mouse Model of Geographic Atrophy: An Antioxidant Gene Therapy Approach.

Manas Ranjan Biswal; Cristhian J Ildefonso; Brian P Rossmiller; Haoyu Mao; Hong Li; Ping Han; Ping Zhu; Yao Tong; Giovani Quinones Valdez; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3189. doi:

ARVO Annual Meeting Abstract June 2015

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

William W Hauswirth; Rachel M Stupay; Ping Zhu; Wen-Tao Deng; Vince Chiodo; Sanford L Boye; Qiuhong Li; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3630. doi:

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Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

AIBP suppresses choroidal neovascularization (CNV) by enhancing cholesterol efflux

Functional Consequences and Cellular Distribution of C1QTNF5 Mutants in Murine Retinal Pigment Epithelium

A Novel Hypoxia-Regulated And Cell -Specific Gene Therapy Elicits Reduced Choroidal Neovascularization

Genetically modified probiotics for oral delivery of Angiotensin-(1-7) confers protection against diabetic complications

Co-expression of human L- or M-opsin restores M-Cone Function in the Opn1mw Knock-out mouse, a model for blue cone monochromacy (BCM)

Restoration of M-cone function in an S-cone only mouse model of human blue cone monochromacy by AAV-mediated expression of human L- or M-opsin

Oral delivery of Angiotensin-(1-7) bioencapsulated in plant cells protect against diabetes-induced retinopathy and other complications

Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD

Beneficial Effects of Combined AT 1 Receptor/Neprilysin Inhibition (ARNI) Versus AT 1 Receptor Blockade Alone in the Diabetic Eye

Reduced Optic Atrophy 1 (OPA1) gene expression in diabetic retina- implication of mitochondrial dynamics in pathogenesis of diabetic retinopathy.

Expression of repressor element 1-silencing transcription factor (REST) gene in rodent and human retina- implication in AMD

Early Sub-retinal Delivery of AAV1- Sod2 Protects the Retina in a Mouse Model of Progressive Retinal Degeneration.

Gene therapy in the Opn1mw Knock-out mouse, a model for blue cone monochromacy, leads to long-term M-cone restoration

Long term restoration of cone function following AAV-mediated gene therapy in CNGA3 -/- Nrl -/- Mice

Beneficial effects of combined AT1 receptor/neprilysin inhibition (ARNI) versus AT1 receptor blockade alone in the diabetic eye

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Opn1mw KO Mice

Delaying Retinal Degeneration in a Mouse Model of Geographic Atrophy: An Antioxidant Gene Therapy Approach.

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

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