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ARVO Annual Meeting Abstract June 2020

A multiomics investigation of risk factors associated with intraocular pressure in the general population

Pirro G Hysi; Anthony P Khawaja; Christopher Hammond

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):979. doi:

ARVO Annual Meeting Abstract June 2020

Iris reflectance measurements in >1000 healthy adult twins: exploration of heritability and associations with eye color

Andrea Kimberly Uy; Xiaofan Jiang; Alex Tanner; Mark Simcoe; Diana Kozareva; Katie Williams; Pirro G Hysi; Christopher Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1866. doi:

ARVO Annual Meeting Abstract June 2020

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Janey Wiggs; Puya Gharahkhani; Eric Jorgenson; Pirro G Hysi; Anthony Khawaja; Sarah Pendergrass; Xikun Han; David Mackey; Christopher Hammond; Michael A Hauser; Louis R Pasquale; Caroline Klaver; Michiaki Kubo; Tin Aung; Jamie E Craig; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1890. doi:

ARVO Annual Meeting Abstract June 2020

Evidence for a causal link between pseudoexfoliation syndrome and myocardial infarction using Mendelian randomization

Marianne T Kennedy Neary; Oliver J Kennedy; George Davey Smith; Pirro G Hysi; Louis R Pasquale; Janey Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2738. doi:

ARVO Annual Meeting Abstract June 2020

Calcium Channel Blocker Use and Risk of Glaucoma in a Large United Kingdom Population

Alan Kastner; Giovanni Montesano; C Gustavo De Moraes; Jae H. Kang; Janey Wiggs; Louis Pasquale; Pirro G Hysi; Sharon Chua; Praveen J Patel; Paul J Foster; Sir Peng T. Khaw; Anthony Khawaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2739. doi:

ARVO Annual Meeting Abstract June 2020

Phenome-wide association analysis on risk variants for age-related macular degeneration reveals shared genetic influences with a wide range of disorders: the Million Veteran Program

Robert Igo; Tyler G Kinzy; Christopher W. Halladay; Dana C. Crawford; Paul B Greenberg; Jack M. Sullivan; Steven J. Fliesler; Wen-Chih Wu; Helene Choquet; Karina Patasova; Eric Jorgenson; Pirro G Hysi; Andrew J Lotery; Jessica Cooke Bailey; Neal S. Peachey; Sudha K Iyengar

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3518. doi:

ARVO Annual Meeting Abstract June 2020

Diminished light adaptation effect seen in cone-driven responses in GRK1 -associated Oguchi disease: evidence for possible rod input to cone adaptation pathways

ZIHE XU; Xiaofan Jiang; James Bellingham; Zakariya Jarrar; Christopher Hammond; Andrew R. Webster; Nigel Davies; Moin Mohamed; Gavin Arno; Pirro G Hysi; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5052. doi:

ARVO Annual Meeting Abstract July 2019

The use of analgesics associated with refractive error shift toward hypermetropia

Karina Patasova; Pirro G Hysi; Christopher J Hammond; Robert Wojciechowski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5844. doi:

ARVO Annual Meeting Abstract July 2019

Genome-wide association study on a large multi-ethnic sample identifies new genetic loci that predispose to keratoconus

Alison J Hardcastle; Pirro G Hysi; Karla Rojas-Lopez; Petra Liskova; Alice E Davidson; Manir Ali; Kathryn P Burdon; David O'Brart; Chris Inglehearn; Paul N Baird; Christopher J Hammond; Stephen J Tuft

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4249. doi:

ARVO Annual Meeting Abstract July 2019

Integrative analysis of GWAS and eQTLs proposes new genetic associations and causal genes for Primary Open Angle Glaucoma

Ayellet Segre; Andrew Hamel; John Rouhana; Anthony P Khawaja; Mark James Simcoe; Christopher J Hammond; Pirro G Hysi; GTEx consortium; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4252. doi:

ARVO Annual Meeting Abstract July 2019

The relationship between refractive error, intraocular pressure, and glaucoma in the UK Biobank.

Robert Wojciechowski; Pirro G Hysi; Peizi Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5222. doi:

ARVO Annual Meeting Abstract July 2019

Gene-drug interactions alter response to prostaglandin analogue treatment of high intraocular pressure and glaucoma

Pirro G Hysi; Mark James Simcoe; Anthony P Khawaja; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5223. doi:

ARVO Annual Meeting Abstract July 2019

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

Katie Williams; Pirro G Hysi; Sonoko Sensaki; Willem Tideman; Seyhan Yazar; juho wedenoja; Mingguang He; Olavi Parssinen; David A Mackey; Caroline C W Klaver; Christopher J Hammond; Seang-Mei Saw

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5226. doi:

ARVO Annual Meeting Abstract July 2019

GWAS of corneal biomechanics identifies over 200 novel associated loci providing additional insight into the genetic aetiology of ocular disease

Mark James Simcoe; Anthony P Khawaja; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5227. doi:

ARVO Annual Meeting Abstract July 2019

The incidence of negative electroretinograms in a healthy adult cohort

Talib Dar; Isabelle Chow; Xiaofan Jiang; Taha Bhatti; Ambreen Tariq; Katie Williams; Pirro G Hysi; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2497. doi:

ARVO Annual Meeting Abstract July 2019

Genome-wide association study of macular ganglion cell complex thickness in 41,504 participants of the UK Biobank study

Hannah Currant; Tomas Fitzgerald; Pirro G Hysi; Charles A Reisman; Qi Yang; Christopher J Hammond; Peng Tee Khaw; Paul J Foster; Praveen Patel; Ewan Birney; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2830. doi:

ARVO Annual Meeting Abstract July 2018

Analyses of the UK Biobank data highlights hundreds of genetic loci and pathways associated with refractive error and myopia

Christopher J Hammond; Pirro G Hysi; Anthony Khawaja; Paul J Foster; Phillippa Cumberland; Peng Tee Khaw; Jugnoo Rahi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):775. doi:

ARVO Annual Meeting Abstract July 2018

Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study

Pirro G Hysi; Tim Spector; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):777. doi:

ARVO Annual Meeting Abstract July 2018

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent

Mark James Simcoe; Manfred Kayser; Tim Spector; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):781. doi:

ARVO Annual Meeting Abstract July 2018

Genome-wide association study of intraocular pressure identifies 83 novel loci

Anthony P Khawaja; Jessica Cooke Bailey; Mark James Simcoe; Robert P Igo; Louis R. Pasquale; Paul J Foster; Janey L Wiggs; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1178. doi:

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A multiomics investigation of risk factors associated with intraocular pressure in the general population

Iris reflectance measurements in >1000 healthy adult twins: exploration of heritability and associations with eye color

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Evidence for a causal link between pseudoexfoliation syndrome and myocardial infarction using Mendelian randomization

Calcium Channel Blocker Use and Risk of Glaucoma in a Large United Kingdom Population

Phenome-wide association analysis on risk variants for age-related macular degeneration reveals shared genetic influences with a wide range of disorders: the Million Veteran Program

Diminished light adaptation effect seen in cone-driven responses in GRK1 -associated Oguchi disease: evidence for possible rod input to cone adaptation pathways

The use of analgesics associated with refractive error shift toward hypermetropia

Genome-wide association study on a large multi-ethnic sample identifies new genetic loci that predispose to keratoconus

Integrative analysis of GWAS and eQTLs proposes new genetic associations and causal genes for Primary Open Angle Glaucoma

The relationship between refractive error, intraocular pressure, and glaucoma in the UK Biobank.

Gene-drug interactions alter response to prostaglandin analogue treatment of high intraocular pressure and glaucoma

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

GWAS of corneal biomechanics identifies over 200 novel associated loci providing additional insight into the genetic aetiology of ocular disease

The incidence of negative electroretinograms in a healthy adult cohort

Genome-wide association study of macular ganglion cell complex thickness in 41,504 participants of the UK Biobank study

Analyses of the UK Biobank data highlights hundreds of genetic loci and pathways associated with refractive error and myopia

Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent

Genome-wide association study of intraocular pressure identifies 83 novel loci

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