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ARVO Annual Meeting Abstract June 2021

Mitochondrial dysfunction causes retraction of Müller cell lateral processes.

Michael J Allingham; Scott Cousins; Priyatham S Mettu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1685.

ARVO Annual Meeting Abstract June 2020

Retinal vein occlusion causes mitochondria dysfunction leading to loss of Müller cell lateral processes and visual dysfunction.

Michael J Allingham; Nomingerel Tserentsoodol; Peter Saloupis; Scott W Cousins; Priyatham S Mettu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1926.

ARVO Annual Meeting Abstract July 2019

Elamipretide, a Mitochondria-Targeted Drug, for the Treatment of Vision Loss in Dry AMD with Noncentral Geographic Atrophy: Results of the Phase 1 ReCLAIM Study

Scott W Cousins; Michael John Allingham; Priyatham S Mettu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):974.

ARVO Annual Meeting Abstract July 2019

Remote diagnosis of referable macular pathology in high disease prevalence communities

Majda Hadziahmetovic; Priyatham S Mettu; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6126.

ARVO Annual Meeting Abstract July 2019

Effects of the Mitochondria-Targeted Drug Elamipretide on Leakage-Independent Vision Loss in Fellow Eyes with Neovascular AMD in the ReCLAIM Study

Priyatham S Mettu; Michael John Allingham; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):358.

ARVO Annual Meeting Abstract July 2019

Elamipretide, a Mitochondrial-Targeted Drug, for the Treatment of Vision Loss in Dry AMD with High Risk Drusen: Results of the Phase 1 ReCLAIM Study

Michael John Allingham; Priyatham S Mettu; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):361.

Retina July 2018

Aldosterone Exposure Causes Increased Retinal Edema and Severe Retinopathy Following Laser-Induced Retinal Vein Occlusion in Mice

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Michael J. Allingham; Nomingerel Tserentsoodol; Peter Saloupis; Priyatham S. Mettu; Scott W. Cousins

Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3355-3365. https://doi.org/10.1167/iovs.17-23073

ARVO Annual Meeting Abstract June 2017

Repetitive periocular delivery of hydroquinone in canines results in dysfunction of central retinal cone photoreceptors

Freya M Mowat; Annie Oh; Melanie Louise Foster; Priyatham S Mettu; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4555.

ARVO Annual Meeting Abstract June 2017

Indocyanine Green Angiography-Directed Verteporfin Photodynamic Therapy for Treatment of Serous Pigment Epithelium Detachments in Neovascular Age-Related Macular Degeneration

Sumeet Jindal; Scott W Cousins; Priyatham S Mettu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1941.

ARVO Annual Meeting Abstract June 2017

The retinal pigment epithelium of the canine area centralis is uniquely susceptible to mitochondrial toxicant damage

Melanie Louise Foster; Regan L Lane; Annie Oh; Steven Nagar; Mary Christine McGahan; Priyatham S Mettu; Scott W Cousins; Freya M Mowat

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5359.

ARVO Annual Meeting Abstract June 2017

Adjunctive Indocyanine Green Angiography-Directed Verteporfin Photodynamic Therapy for the Treatment of Persistent Disease Activity in Neovascular AMD

Priyatham S Mettu; Michael J Allingham; Peter Nicholas; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1931.

Physiology and Pharmacology May 2017

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration

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Joanne C. Wen; Ester Reina-Torres; Joseph M. Sherwood; Pratap Challa; Katy C. Liu; Guorong Li; Jason Y. H. Chang; Scott W. Cousins; Stefanie G. Schuman; Priyatham S. Mettu; W. Daniel Stamer; Darryl R. Overby; R. Rand Allingham
TAGS: exudative age-related macular degeneration, injections, intraocular pressure, eye, ocular hypertension
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1893-1898. https://doi.org/10.1167/iovs.16-20786

Articles March 2017

A Quantitative Approach to Predict Differential Effects of Anti-VEGF Treatment on Diffuse and Focal Leakage in Patients with Diabetic Macular Edema: A Pilot Study

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Michael J. Allingham; Dibyendu Mukherjee; Erin B. Lally; Hossein Rabbani; Priyatham S. Mettu; Scott W. Cousins; Sina Farsiu
TAGS: anti-vascular endothelial growth factor therapy, diabetic macular edema, pilot projects
Trans. Vis. Sci. Tech.. 2017; 6(2):7. https://doi.org/10.1167/tvst.6.2.7

ARVO Annual Meeting Abstract September 2016

Neovascular Morphology by ICG Angiography and Response to Loading-Dose Anti-VEGF Therapy in Patients with Neovascular AMD

Priyatham S Mettu; Michael J Allingham; Peter C Nicholas; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Feasibility and acceptance of retinal imaging in a medical clinic by non-expert imagers

Peter C Nicholas; Priyatham S Mettu; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1661.

ARVO Annual Meeting Abstract September 2016

A quantitative approach to predict differential effects of anti-VEGF treatment on diffuse and focal leakage in patients with diabetic macular edema.

Michael J Allingham; Dibyendu Mukherjee; Erin Lally; Hossein Rabbani; Priyatham S Mettu; Scott W Cousins; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2076.

ARVO Annual Meeting Abstract September 2016

Mitochondrial Dysfunction in Experimental Mouse Models of SubRPE Deposit Formation and Reversal by the Mito-Reparative Drug MTP-131

Scott W Cousins; Peter Saloupis; Mulugu V. Brahmajoti; Priyatham S Mettu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2126.

Multidisciplinary Ophthalmic Imaging April 2016

Semiautomatic Segmentation of Rim Area Focal Hyperautofluorescence Predicts Progression of Geographic Atrophy Due to Dry Age-Related Macular Degeneration

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Michael J. Allingham; Qing Nie; Eleonora M. Lad; Daniel J. Izatt; Priyatham S. Mettu; Scott W. Cousins; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):2283-2289. https://doi.org/10.1167/iovs.15-19008

ARVO Annual Meeting Abstract June 2015

The mitochondria-targeted peptide MTP-131 prevents hydroquinone-mediated persistent injury phenotype in cultured retinal pigment epithelium cells

Scott W Cousins; Priyatham S Mettu; Mulugu V. Brahmajothi

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):829.

ARVO Annual Meeting Abstract June 2015

Repetitive periocular injection of hydroquinone promotes mitochondrial dysfunction in retinal pigment epithelium of mouse eyes

Riikka Hess; Mulugu V. Brahmajothi; Peter Saloupis; Priyatham S Mettu; Scott W Cousins

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1277.

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Mitochondrial dysfunction causes retraction of Müller cell lateral processes.

Retinal vein occlusion causes mitochondria dysfunction leading to loss of Müller cell lateral processes and visual dysfunction.

Elamipretide, a Mitochondria-Targeted Drug, for the Treatment of Vision Loss in Dry AMD with Noncentral Geographic Atrophy: Results of the Phase 1 ReCLAIM Study

Remote diagnosis of referable macular pathology in high disease prevalence communities

Effects of the Mitochondria-Targeted Drug Elamipretide on Leakage-Independent Vision Loss in Fellow Eyes with Neovascular AMD in the ReCLAIM Study

Elamipretide, a Mitochondrial-Targeted Drug, for the Treatment of Vision Loss in Dry AMD with High Risk Drusen: Results of the Phase 1 ReCLAIM Study

Aldosterone Exposure Causes Increased Retinal Edema and Severe Retinopathy Following Laser-Induced Retinal Vein Occlusion in Mice

Repetitive periocular delivery of hydroquinone in canines results in dysfunction of central retinal cone photoreceptors

Indocyanine Green Angiography-Directed Verteporfin Photodynamic Therapy for Treatment of Serous Pigment Epithelium Detachments in Neovascular Age-Related Macular Degeneration

The retinal pigment epithelium of the canine area centralis is uniquely susceptible to mitochondrial toxicant damage

Adjunctive Indocyanine Green Angiography-Directed Verteporfin Photodynamic Therapy for the Treatment of Persistent Disease Activity in Neovascular AMD

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration

A Quantitative Approach to Predict Differential Effects of Anti-VEGF Treatment on Diffuse and Focal Leakage in Patients with Diabetic Macular Edema: A Pilot Study

Neovascular Morphology by ICG Angiography and Response to Loading-Dose Anti-VEGF Therapy in Patients with Neovascular AMD

Feasibility and acceptance of retinal imaging in a medical clinic by non-expert imagers

A quantitative approach to predict differential effects of anti-VEGF treatment on diffuse and focal leakage in patients with diabetic macular edema.

Mitochondrial Dysfunction in Experimental Mouse Models of SubRPE Deposit Formation and Reversal by the Mito-Reparative Drug MTP-131

Semiautomatic Segmentation of Rim Area Focal Hyperautofluorescence Predicts Progression of Geographic Atrophy Due to Dry Age-Related Macular Degeneration

The mitochondria-targeted peptide MTP-131 prevents hydroquinone-mediated persistent injury phenotype in cultured retinal pigment epithelium cells

Repetitive periocular injection of hydroquinone promotes mitochondrial dysfunction in retinal pigment epithelium of mouse eyes

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