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Immunology and Microbiology July 2025

The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation

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Xuexue Cui; Caijiao Yi; Jian Liu; Jinyan Qi; Wen Deng; Xiangling Yuan; Ruiqi Zhou; Mei Chen; Qiang Xiang; Heping Xu
TAGS: antibiotics, gastrointestinal microbiome, mice, retinal injuries, wounds and injuries, laser injuries, attenuation, lasers
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):6. https://doi.org/10.1167/iovs.66.9.6

Includes: Supplemental Content

Glaucoma June 2025

Multi-Omic Insight Into the Molecular Networks of Mitochondrial Dysfunction in the Pathogenesis of Primary Open-Angle Glaucoma

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Li-Hua Chen; Hai-Jiang Zhang; Qing-Ao Xiao
TAGS: methylation, mitochondria, mitochondrial diseases, open-angle glaucoma, pathogenesis, pathophysiology, multiomics, genes
Trans. Vis. Sci. Tech.. 2025; 14(6):37. https://doi.org/10.1167/tvst.14.6.37

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

Study on the correlation between repeated low-level red light-induced afterimage and axial changes in myopia control

Yawen Zhu; Xiaoli Qi; Gang Ding; Xuehan Qian; Gang Yu; Feng Zhang; Lili Guo; Wenjing Ku

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5197.

ARVO Annual Meeting Abstract June 2025

The Effect of LED Red Light on Axial Length in Children with Hyperopia

ya Li; Xiaoli Qi; Gang Ding; Xuehan Qian; Gang Yu; Feng Zhang; Lili Guo; Wenjing Ku

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2181.

Cornea June 2025

Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice

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Ning Wang; Yizhou Li; Xiaolei Wang; Lingling Yang; Jing Zhang; Jun Cheng; Xiaoyue Jiang; Xia Qi; Chao Wei; Qingjun Zhou; Ya Li; Suxia Li

Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):28. https://doi.org/10.1167/iovs.66.6.28

Includes: Supplemental Content

Retina March 2025

Carboxyamidotriazole Complexed to PLGA Is Safe, Effective, and Durable in Models of Neovascular Retinal Disease

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Sergio Li Calzi; Ayaka Fujihashi; Dibyendu Chakraborty; Yvonne Adu-Rutledge; Ram Prasad; Edgar L. V. Ready; Sarbodeep Paul; Srikanth Kakumanu; Xiaoping Qi; Michael E. Boulton; Alan J. Franklin; Bob H. Katz; Maria B. Grant
TAGS: aflibercept, choroidal neovascularization, implants, lasers, oryctolagus cuniculus, polymers, retinal diseases, intravitreal injections, mice, injections
Trans. Vis. Sci. Tech.. 2025; 14(3):21. https://doi.org/10.1167/tvst.14.3.21

Retina January 2025

Pulsed Ultrasound-Mediated Drug Delivery Enhancement Through Human Sclera

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Shuqi You; Suqian Wu; Shicheng Yang; Zhenyang Zhao; Wei Chen; Xiangwu Chen; Huan Wang; Qing Xia; Jiawei Xiong; Hongsheng Zhou; Xiaofen Mo
TAGS: drug delivery systems, pus, sclera, ultrasonography, nipple discharge aspiration, sodium fluoride
Trans. Vis. Sci. Tech.. 2025; 14(1):7. https://doi.org/10.1167/tvst.14.1.7

Includes: Supplemental Content

Retina December 2024

Mettl3 -Mediated m 6 A Modification is Essential for Visual Function and Retinal Photoreceptor Survival

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Xiaoyan Jiang; Kuanxiang Sun; Yudi Fan; Qianchun Xiang; Rong Zou; Yeming Yang; Xianjun Zhu; Wenjing Liu
TAGS: mice, photoreceptors, proteins, rod photoreceptors, vision, retina, retinal cone, western blotting, candidate disease gene
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):40. https://doi.org/10.1167/iovs.65.14.40

Includes: Supplemental Content

Cornea September 2024

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

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Yunhai Dai; Shilan Mao; Xinyi Zang; Hongqi Ge; Jing Feng; Yalin Wang; Xia Qi; Lingling Yang; Qingjun Zhou; Xiaolei Wang
TAGS: cornea, diabetes mellitus, type 2, human herpesvirus 1, infections, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):36. https://doi.org/10.1167/iovs.65.11.36

Includes: Supplemental Content

Biochemistry and Molecular Biology August 2024

Inhibition of Heme Oxygenase 1 Suppresses Growth, Migration, and Invasion, and Regulates Tumor-Infiltrating CD8 + T Cells and in Uveal Melanoma

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Chen Hou; Qi Wan; Lirong Xiao; Qing Xiao; Meixia Zhang; Naihong Yan
TAGS: heme oxygenase (decyclizing), intraocular melanoma, neoplasms, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):37. https://doi.org/10.1167/iovs.65.10.37

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Genome-wide Screening Identifies Novel Genetic and Epigenetic Factors for the Rejuvenation and Enhancement of RPE to Alleviate Age-related Macular Degeneration

Yuancheng Ryan Lu; Margarete Karg; Lindsey A Chew; Kat Kajderowicz; Daisy Y Shu; Xiaojie Qiu; Nasrin Refaian; Shintaro Shirahama; Zhengping Hu; Tessa Bertozzi; David Sinclair; Magali Saint-Geniez; Patricia A D'Amore; Catherine Bowes Rickman; Bruce Ksander; Jonathan Weissman

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5307.

ARVO Annual Meeting Abstract June 2024

The Prevalence of Congenital Epiblepharon and High BMI in Chinese School–age Children

Shishu Huang; Xuehan Qian; Xiaoli Qi; Nan Wei

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5251.

ARVO Annual Meeting Abstract June 2024

Impact of donor and host age on systemic stem cell therapy to treat a mouse model of AMD

Brenton T. Bicknell; Carolina Francelin Rovarotto; Xiaoping Qi; Maria B Grant; Michael Boulton

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):710.

Cornea June 2024

Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches

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Shanmei Lyu; Ting Zhang; Peng Peng; Dingwen Cao; Li Ma; Yang Yu; Yanling Dong; Xiaolin Qi; Chao Wei
TAGS: candida albicans, cornea, fungal keratitis, genetics, keratitis, pathogenesis, pharmacology, signal transduction, nlr family, pyrin domain-containing 3 protein, symptom aggravating factors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):13. https://doi.org/10.1167/iovs.65.6.13

Includes: Supplemental Content

Physiology and Pharmacology April 2024

CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

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Linyan Ma; Lingling Yang; Xiaolei Wang; Leilei Zhao; Xiaofei Bai; Xia Qi; Qing Chen; Ya Li; Qingjun Zhou
TAGS: bodily secretions, calcitonin gene-related peptide, cornea, lacrimal gland, mice, sensory nerves, trpv1 receptor, capsaicin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):30. https://doi.org/10.1167/iovs.65.4.30

Includes: Supplemental Content

Cornea December 2023

Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b + Ly6G + Cells and Increasing the Viral Load in the Cornea

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Jing Feng; Lingling Yang; Lili Ran; Xia Qi; Xiaolei Wang; Yangyang Zhang; Zongzheng Zou; Ting Liu; Xiaochuan Wang; Yang Yu; Xiaodong Sun; Qingjun Zhou
TAGS: cornea, human herpesvirus 1, infections, keratitis, herpetic, macrophage-1 antigen, mice, symptom aggravating factors, viral load result
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):24. https://doi.org/10.1167/iovs.64.15.24

Includes: Supplemental Content

Lens September 2023

Vault Height Is a Key Predictive Factor for Anterior Segment Measurement Error by IOLMaster 700 in Eyes With Phakic Intraocular Lens

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Jiaqing Zhang; Fei Chen; Xiaotong Han; Xiaozhang Qiu; Zhenzhen Liu; Xiaoyun Chen; Guangming Jin; Bo Qu; Huan Yao; Yiming Ye; Keming Yu; Xuhua Tan; Lixia Luo
TAGS: biometry, eye, intraocular lens implant device, measurement error, predictor variable, implantation procedure
Trans. Vis. Sci. Tech.. 2023; 12(9):16. https://doi.org/10.1167/tvst.12.9.16

Includes: Supplemental Content

Cornea & External Disease March 2023

Agreement of Total Keratometry and Posterior Keratometry Among IOLMaster 700, CASIA2, and Pentacam

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Aixia Jin; Xiaotong Han; Jiaqing Zhang; Xiaozhang Qiu; Yifan Zhang; Bo Qu; Xuhua Tan; Lixia Luo
TAGS: astigmatism, keratometry
Trans. Vis. Sci. Tech.. 2023; 12(3):13. https://doi.org/10.1167/tvst.12.3.13

Includes: Supplemental Content

Cornea January 2023

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

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Lili Ran; Jing Feng; Xia Qi; Ting Liu; Benxiang Qi; Kai Jiang; Zhenzhen Zhang; Yang Yu; Qingjun Zhou; Lixin Xie
TAGS: cornea, epithelium, mice, wound healing
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):19. https://doi.org/10.1167/iovs.64.1.19

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Effects of Atropine 0.01% on Refractive Errors in Myopic Children

Yuliang Wang; Xingtao Zhou; Xiaomei Qu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4316 – A0021.

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The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation

Multi-Omic Insight Into the Molecular Networks of Mitochondrial Dysfunction in the Pathogenesis of Primary Open-Angle Glaucoma

Study on the correlation between repeated low-level red light-induced afterimage and axial changes in myopia control

The Effect of LED Red Light on Axial Length in Children with Hyperopia

Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice

Carboxyamidotriazole Complexed to PLGA Is Safe, Effective, and Durable in Models of Neovascular Retinal Disease

Pulsed Ultrasound-Mediated Drug Delivery Enhancement Through Human Sclera

Mettl3 -Mediated m 6 A Modification is Essential for Visual Function and Retinal Photoreceptor Survival

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

Inhibition of Heme Oxygenase 1 Suppresses Growth, Migration, and Invasion, and Regulates Tumor-Infiltrating CD8 + T Cells and in Uveal Melanoma

Genome-wide Screening Identifies Novel Genetic and Epigenetic Factors for the Rejuvenation and Enhancement of RPE to Alleviate Age-related Macular Degeneration

The Prevalence of Congenital Epiblepharon and High BMI in Chinese School–age Children

Impact of donor and host age on systemic stem cell therapy to treat a mouse model of AMD

Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches

CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b + Ly6G + Cells and Increasing the Viral Load in the Cornea

Vault Height Is a Key Predictive Factor for Anterior Segment Measurement Error by IOLMaster 700 in Eyes With Phakic Intraocular Lens

Agreement of Total Keratometry and Posterior Keratometry Among IOLMaster 700, CASIA2, and Pentacam

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

Effects of Atropine 0.01% on Refractive Errors in Myopic Children

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