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Artificial Intelligence February 2025

Deep Learning Approaches to Predict Geographic Atrophy Progression Using Three-Dimensional OCT Imaging

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Kenta Yoshida; Neha Anegondi; Adam Pely; Miao Zhang; Frederic Debraine; Karthik Ramesh; Verena Steffen; Simon S. Gao; Catherine Cukras; Christina Rabe; Daniela Ferrara; Richard F. Spaide; SriniVas R. Sadda; Frank G. Holz; Qi Yang
TAGS: age-related macular degeneration, nonexudative, datasets, deep learning, diagnostic imaging, growth rate
Trans. Vis. Sci. Tech.. 2025; 14(2):11. https://doi.org/10.1167/tvst.14.2.11

Includes: Supplemental Content

Retina November 2024

Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy

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Juan Zhang; Lu Ruan; Chen Jiang; Qian Yang; Qing Chang; Xin Huang
TAGS: familial exudative vitreoretinopathies
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):4. https://doi.org/10.1167/iovs.65.13.4

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

From Preparatory Attention to Stimulus Selection: Neural Mechanisms Revealed by Multivariate Analysis of fMRI Data

Qiang Yang; Sreenivasan Meyyappan; George R Mangun; Mingzhou Ding

Journal of Vision. 2024; 24(10):275. https://doi.org/10.1167/jov.24.10.275

Vision Sciences Society Annual Meeting Abstract September 2024

Decoding Feature-Based Attention in Visual Cortex

Rylee Faherty; Qiang Yang; Maeve R. Boylan; Andreas Keil; Mingzhou Ding

Journal of Vision. 2024; 24(10):1108. https://doi.org/10.1167/jov.24.10.1108

Artificial Intelligence August 2024

Topographic Clinical Insights From Deep Learning–Based Geographic Atrophy Progression Prediction

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Julia Cluceru; Neha Anegondi; Simon S. Gao; Aaron Y. Lee; Eleonora M. Lad; Usha Chakravarthy; Qi Yang; Verena Steffen; Michel Friesenhahn; Christina Rabe; Daniela Ferrara
TAGS: ablation, age-related macular degeneration, nonexudative, datasets, deep learning, masks, diagnostic imaging, growth rate, pixel, shape
Trans. Vis. Sci. Tech.. 2024; 13(8):6. https://doi.org/10.1167/tvst.13.8.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Predicting functional outcomes for different treatment durations of faricimab in diabetic macular edema (DME)

Yusuke Kikuchi; Javid Abderezaei; Matthew McLeod; Chen Chen; Acner Camino Benech; Daniela Ferrara; Neha Anegondi; Qi Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3754.

ARVO Annual Meeting Abstract June 2024

Adenosine receptor 2A regulates subretinal fibrosis through SDH-Succinate signaling pathway

Qiuhua Yang; Yongfeng Cai; Qian Ma; Peishan Xu; Wei Li; Ruth B Caldwell; Akrit Sodhi; Yuqing Huo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4956.

ARVO Annual Meeting Abstract June 2024

Adaptive optics imaging of cone photoreceptors and RPE cells based on detection of multiply scattered light from a wavelength-swept 3 MHz OCT light source

Andrew J. Bower; Qiang Yang; Bartlomiej Kowalski; Nancy Aguilera; Vineeta Das; Joanne Li; Tao Liu; Alfredo Dubra; Johnny Tam

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4329.

ARVO Annual Meeting Abstract June 2024

Activation of Sigma 1 Receptor prevents pathological angiogenesis and subretinal fibrosis in an experimental model of choroidal neovascularization (CNV)

Jing Wang; Qiuhua Yang; Yuqing Huo; Sylvia B Smith

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4315.

ARVO Annual Meeting Abstract June 2024

Towards automated optical coherence tomography (OCT) data analysis for a real-world diabetic macular edema (DME) treatment cohort

James Talks; Tunde Peto; Xiaoyong Wang; Anda Gershon; Geeta Menon; Faruque Ghanchi; Xin Chen; Vivian Look; Huanxiang Lu; Michael H. Chen; Daniela Ferrara; Gloria Chi; Qi Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5956.

ARVO Annual Meeting Abstract June 2024

Transport of β-amyloid from Brain to Eye Causes Retinal Degeneration in Alzheimer’s Disease

Qiuchen Cao; Shige Yang; Xiaowei Wang; Qiuhua Yang; Weijie Chen; Yanchi Wu; Ming Xiao; Yuqing Huo; Qinghuai Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5846.

ARVO Annual Meeting Abstract June 2024

Generalizability of foundation models for geographic atrophy (GA) lesion segmentation in fundus autofluorescence (FAF)

Eric Gros; Matthew McLeod; Yusuke Kikuchi; Julia Cluceru; Neha Anegondi; Simon S. Gao; Christina Rabe; Daniela Ferrara; Qi Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2391.

ARVO Annual Meeting Abstract June 2024

Efficient In-vitro and In-vivo CRISPR RNA Targeting Therapy of HG202 for Macular Degeneration

Linyu Shi; Weiwei Wu; Qi Yang; Sheng He; Mengke Zhu; Chenhua Yang; Shaoran Wang; Xing Wang; Xuan Yao; Alvin Luk; Hui Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6517.

ARVO Annual Meeting Abstract June 2024

Faricimab treatment response prediction in diabetic macular edema (DME) using deep learning on optical coherence tomography (OCT) and clinical data

Matthew McLeod; Javid Abderezaei; Yusuke Kikuchi; Chen Chen; Acner Camino Benech; Daniela Ferrara; Neha Anegondi; Qi Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5645.

ARVO Annual Meeting Abstract June 2024

In-vivo Validation of HG004 Gene Replacement Therapy for Inherited Blindness

Weiwei Wu; Sheng He; Qi Yang; Chenhua Yang; Mengke Zhu; Shaoran Wang; Xuan Yao; Hui Yang; Alvin Luk; Linyu Shi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5091.

Visual Psychophysics and Physiological Optics May 2024

Near Infrared Autofluorescence Lifetime Imaging of Human Retinal Pigment Epithelium Using Adaptive Optics Scanning Light Ophthalmoscopy

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Karteek Kunala; Janet A. H. Tang; Kristen E. Bowles Johnson; Khang T. Huynh; Keith Parkins; Hye-Jin Kim; Qiang Yang; Janet R. Sparrow; Jennifer J. Hunter
TAGS: autofluorescence, diagnostic imaging, eye, ophthalmoscopy, optics, retinal pigment epithelium, fluorescence, mice, melanins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):27. https://doi.org/10.1167/iovs.65.5.27

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics April 2024

Fluorescence Lifetime Imaging of Human Retinal Pigment Epithelium in Pentosan Polysulfate Toxicity Using Adaptive Optics Scanning Light Ophthalmoscopy

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Kristen E. Bowles Johnson; Janet A. H. Tang; Karteek Kunala; Khang T. Huynh; Keith Parkins; Qiang Yang; Jennifer J. Hunter
TAGS: diagnostic imaging, fluorescence, ophthalmoscopy, optics, pentosan sulfuric polyester, retinal pigment epithelium, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):27. https://doi.org/10.1167/iovs.65.4.27

Genetics September 2023

Dysregulated Arginine Metabolism Is Linked to Retinal Degeneration in Cep250 Knockout Mice

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Lue Xiang; Qiao-Li Yang; Bin-Tao Xie; Hui-Yi Zeng; Liu-Jun Ding; Feng-Qin Rao; Tong Yan; Fan Lu; Qi Chen; Xiu-Feng Huang
TAGS: arginine, mice, retina, retinal degeneration, metabolism, mice, knockout, metabolomics, proteins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):2. https://doi.org/10.1167/iovs.64.12.2

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract September 2023

Contributed Session III: In vivo calcium imaging of macaque foveolar retinal ganglion cells reveals spatiochromatic receptive field properties

Tyler Godat; Nicolas P. Cottaris; Sara Patterson; Kendall Kohout; Keith Parkins; Qiang Yang; Jennifer M. Strazzeri; Juliette E. McGregor; David H. Brainard; William H. Merigan; David R. Williams
TAGS: calcium, diagnostic imaging, macaca, retinal ganglion cells
Journal of Vision. 2023; 23(11):32. https://doi.org/10.1167/jov.23.11.32

Optica Fall Vision Meeting Abstract September 2023

Contributed Session I: Spectral, Spatial and Temporal Response Properties of Foveal Ganglion Cells

Sara Patterson; Tyler Godat; Kendall Kohout; Qiang Yang; William Merigan; David Williams
TAGS: ganglia
Journal of Vision. 2023; 23(11):9. https://doi.org/10.1167/jov.23.11.9

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Deep Learning Approaches to Predict Geographic Atrophy Progression Using Three-Dimensional OCT Imaging

Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy

From Preparatory Attention to Stimulus Selection: Neural Mechanisms Revealed by Multivariate Analysis of fMRI Data

Decoding Feature-Based Attention in Visual Cortex

Topographic Clinical Insights From Deep Learning–Based Geographic Atrophy Progression Prediction

Predicting functional outcomes for different treatment durations of faricimab in diabetic macular edema (DME)

Adenosine receptor 2A regulates subretinal fibrosis through SDH-Succinate signaling pathway

Adaptive optics imaging of cone photoreceptors and RPE cells based on detection of multiply scattered light from a wavelength-swept 3 MHz OCT light source

Activation of Sigma 1 Receptor prevents pathological angiogenesis and subretinal fibrosis in an experimental model of choroidal neovascularization (CNV)

Towards automated optical coherence tomography (OCT) data analysis for a real-world diabetic macular edema (DME) treatment cohort

Transport of β-amyloid from Brain to Eye Causes Retinal Degeneration in Alzheimer’s Disease

Generalizability of foundation models for geographic atrophy (GA) lesion segmentation in fundus autofluorescence (FAF)

Efficient In-vitro and In-vivo CRISPR RNA Targeting Therapy of HG202 for Macular Degeneration

Faricimab treatment response prediction in diabetic macular edema (DME) using deep learning on optical coherence tomography (OCT) and clinical data

In-vivo Validation of HG004 Gene Replacement Therapy for Inherited Blindness

Near Infrared Autofluorescence Lifetime Imaging of Human Retinal Pigment Epithelium Using Adaptive Optics Scanning Light Ophthalmoscopy

Fluorescence Lifetime Imaging of Human Retinal Pigment Epithelium in Pentosan Polysulfate Toxicity Using Adaptive Optics Scanning Light Ophthalmoscopy

Dysregulated Arginine Metabolism Is Linked to Retinal Degeneration in Cep250 Knockout Mice

Contributed Session III: In vivo calcium imaging of macaque foveolar retinal ganglion cells reveals spatiochromatic receptive field properties

Contributed Session I: Spectral, Spatial and Temporal Response Properties of Foveal Ganglion Cells

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