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ARVO Annual Meeting Abstract June 2025

Single Intrastromal Injection of CRISPR-Cas9 Therapy GEB-401 for TGFBI Corneal Dystrophies in NHPs.

changchang xin; Qian Luo; Xichen Wan; Hua Lu; Mingrui Cheng; Zihua Jiang; Xujiao Zhou; Martin Chan; Xingtao Zhou; Zongli Zheng; Jiaxu Hong

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4249.

ARVO Annual Meeting Abstract June 2025

Effect of Dietary Intervention on the Retina in APOE4 Knock-in Mouse Model of Alzheimer’s Disease

Ashay D Bhatwadekar; Surabhi Abhyankar; Qianyi Luo; Gabriella Hartman; Neha Mahajan; Timothy William Corson; Adrian Oblak; Bruce T Lamb

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4842.

ARVO Annual Meeting Abstract June 2025

APOE4 causes Kir4.1 and Müller Cell Dysfunction via Mitochondrial ROS Accumulation

Surabhi Abhyankar; Yucheng Xiao; Neha Mahajan; Qianyi Luo; Theodore R. Cummins; Adrian Oblak; Bruce T Lamb; Timothy William Corson; Ashay D Bhatwadekar

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4809.

Physiology and Pharmacology December 2024

Characterization of the Ocular Phenotype in a Col4a3 Knockout Mouse Model of Alport Syndrome

PDF

Ameya Belamkar; Qianyi Luo; Neha Mahajan; Surabhi Abhyankar; Bryce A. Jones; Rupinder Kaur Sodhi; Padmanabhan P. Pattabiraman; Moshe Levi; Ashay D. Bhatwadekar
TAGS: collagen, cornea, eye, eye diseases, fluorescent antibody technique, hereditary nephritis, lens (device), mice, mice, knockout, phenotype
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):29. https://doi.org/10.1167/iovs.65.14.29

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Retinal Dysfunction in Alzheimer's Disease (AD): A Dual Investigation into the Impact of APOE4 and Diabetes

Surabhi Abhyankar; Qianyi Luo; Neha Mahajan; Gabriella Hartman; Timothy William Corson; Adrian Oblak; Bruce Lamb; Ashay D Bhatwadekar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):334.

ARVO Annual Meeting Abstract June 2024

Central Overexpression of BMAL1 Improves Circadian Rhythm and Retinal Health in db/db mice

Ashay D Bhatwadekar; Jodi Lukkes; Neha Mahajan; Surabhi Abhyankar; Andrei Molosh; Qianyi Luo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):304.

ARVO Annual Meeting Abstract June 2024

Hematopoietic Stem Cell Transcriptome as a Potential Biomarker for Diabetic Retinopathy

Neha Mahajan; Qianyi Luo; Surabhi Abhyankar; Amir Reza Hajrasouliha; Ashay D Bhatwadekar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3833.

ARVO Annual Meeting Abstract June 2024

The Profibrotic Phenotype in Col4a3 Knockout Mouse Model of Alport Syndrome

Ameya Vinayak Belamkar; Qianyi Luo; Neha Mahajan; Surabhi Abhyankar; Bryce Jones; Padmanabhan P Pattabiraman; Moshe Levi; Ashay D Bhatwadekar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5819.

Cornea June 2023

Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing

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Xuan Liu; Zedu Cui; Xi Chen; Yan Li; Jin Qiu; Yuke Huang; Xiao Wang; Shuilian Chen; Qian Luo; Pei Chen; Jing Zhuang; Keming Yu
TAGS: cornea, dry eye syndromes, ferroptosis, lacrimal gland, neurons
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):27. https://doi.org/10.1167/iovs.64.7.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Characterization of Ocular Phenotype of COL4A3 Knockout Mice

Ameya Belamkar; Qianyi Luo; Bryce Jones; Moshe Levi; Ashay D Bhatwadekar

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4782.

ARVO Annual Meeting Abstract June 2023

Assessment of peripheral circulating angiogenic cells and inflammatory markers in diabetic retinopathy individuals

Neha Mahajan; Qianyi Luo; Amir Reza Hajrasouliha; Ashay D Bhatwadekar

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):585.

Cornea April 2023

The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability

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Xiao Wang; Zedu Cui; Xi Chen; Qian Luo; Zihua Jiang; Xuan Liu; Yuke Huang; Jingyi Jiang; Shuilian Chen; Jin Qiu; Yan Li; Keming Yu; Jing Zhuang
TAGS: choroidal neovascularization, cxcr4 receptors, corneal neovascularization, hypoxia, cornea
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):10. https://doi.org/10.1167/iovs.64.4.10

Includes: Supplemental Content

Retinal Cell Biology March 2023

Lithium Chloride Exerts Anti-Inflammatory and Neuroprotective Effects by Inhibiting Microglial Activation in LPS-Induced Retinal Injury

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Nandan Wu; Qian Luo; Yuke Huang; Linxi Wan; Xiangtao Hou; Zihua Jiang; Yan Li; Jin Qiu; Pei Chen; Keming Yu; Jing Zhuang; Ying Yang
TAGS: anti-inflammatory agents, lithium chloride, mice, microglia, neuroinflammatory diseases, neuroprotective effect, proteins, retinal injuries, fluorescent antibody technique, 1-phosphatidylinositol 3-kinase
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):35. https://doi.org/10.1167/iovs.64.3.35

Includes: Supplemental Content

Retina October 2022

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

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Shuilian Chen; Xi Chen; Ping Zhang; Shuxia Chen; Xiao Wang; Qian Luo; Zedu Cui; Yuke Huang; Linxi Wan; Xiangtao Hou; Huan Yao; Xuan Liu; Anqi He; Zihua Jiang; Jin Qiu; Yan Li; Keming Yu; Jing Zhuang
TAGS: bioinformatics, genes, retinoblastoma, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):28. https://doi.org/10.1167/iovs.63.11.28

Includes: Supplemental Content

Retina August 2021

Ubiquitination-Related miRNA–mRNA Interaction Is a Potential Mechanism in the Progression of Retinoblastoma

PDF

Xi Chen; Shuilian Chen; Zihua Jiang; Qian Gong; Danni Tang; Qian Luo; Xuan Liu; Shengyu He; Anqi He; Yihui Wu; Jin Qiu; Yan Li; Xiao Wang; Keming Yu; Jing Zhuang
TAGS: genes, micrornas, retinoblastoma, rna, messenger, ubiquitination, proton pump inhibitors, polymerase chain reaction, cell survival
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):3. https://doi.org/10.1167/iovs.62.10.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Dapagliflozin treatment protects from diabetic retinopathy

Ashay D Bhatwadekar; Deepa Mathew; Hurshdeep Dhami; Erika Bello; Qianyi Luo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1161.

Retinal Cell Biology June 2020

Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes

PDF

Alpha Alex; Qianyi Luo; Deepa Mathew; Rong Di; Ashay D. Bhatwadekar
TAGS: metformin, mice, diabetes mellitus, type 2, diabetes mellitus, circadian rhythms, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):46. https://doi.org/10.1167/iovs.61.6.46

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in db/db mice

Ashay D Bhatwadekar; Alpha Alex; Rong Di; Deepa Mathew; Qianyi Luo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2723.

Retinal Cell Biology May 2019

The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1

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Qianyi Luo; Yucheng Xiao; Alpha Alex; Theodore R. Cummins; Ashay D. Bhatwadekar
TAGS: circadian rhythms, diabetes mellitus, diabetes mellitus, type 2, irs1 protein, human, mice, rhythm, insulin receptor, clock gene
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):1928-1936. https://doi.org/10.1167/iovs.18-26045

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Clock Gene Bmal1 Mediates Insulin Receptor Signaling and Kir4.1 Channels in Retinal Müller Cells

Ashay D Bhatwadekar; Yucheng Xiao; Theodore Cummins; Qianyi Luo

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3555.

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Single Intrastromal Injection of CRISPR-Cas9 Therapy GEB-401 for TGFBI Corneal Dystrophies in NHPs.

Effect of Dietary Intervention on the Retina in APOE4 Knock-in Mouse Model of Alzheimer’s Disease

APOE4 causes Kir4.1 and Müller Cell Dysfunction via Mitochondrial ROS Accumulation

Characterization of the Ocular Phenotype in a Col4a3 Knockout Mouse Model of Alport Syndrome

Retinal Dysfunction in Alzheimer's Disease (AD): A Dual Investigation into the Impact of APOE4 and Diabetes

Central Overexpression of BMAL1 Improves Circadian Rhythm and Retinal Health in db/db mice

Hematopoietic Stem Cell Transcriptome as a Potential Biomarker for Diabetic Retinopathy

The Profibrotic Phenotype in Col4a3 Knockout Mouse Model of Alport Syndrome

Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing

Characterization of Ocular Phenotype of COL4A3 Knockout Mice

Assessment of peripheral circulating angiogenic cells and inflammatory markers in diabetic retinopathy individuals

The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability

Lithium Chloride Exerts Anti-Inflammatory and Neuroprotective Effects by Inhibiting Microglial Activation in LPS-Induced Retinal Injury

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

Ubiquitination-Related miRNA–mRNA Interaction Is a Potential Mechanism in the Progression of Retinoblastoma

Dapagliflozin treatment protects from diabetic retinopathy

Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes

Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in db/db mice

The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1

Clock Gene Bmal1 Mediates Insulin Receptor Signaling and Kir4.1 Channels in Retinal Müller Cells

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