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Retinal Cell Biology August 2019

Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material

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Qitao Zhang; Feriel Presswalla; Melissa Calton; Carol Charniga; Jeffrey Stern; Sally Temple; Douglas Vollrath; David N. Zacks; Robin R. Ali; Debra A. Thompson; Jason M. L. Miller
TAGS: fetus, lipofuscin, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3468-3479. doi: https://doi.org/10.1167/iovs.19-26690

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Primary fetal RPE cultures resist accumulation and toxicity of lipofuscin-like material, and accumulated material can be further reduced by autophagy induction.

Qitao Zhang; Feriel Presswalla; Anne McCusker; Carol Charniga; Melissa A Calton; Douglas Vollrath; sally Temple; Jeffrey Stern; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1718. doi:

ARVO Annual Meeting Abstract July 2018

Measuring and Modulating Lipid Handling Pathways in the RPE: Implications for Age-Related Macular Degeneration

Jason Miller; Feriel Presswalla; Qitao Zhang; David N Zacks; Debra A Thompson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4032. doi:

ARVO Annual Meeting Abstract June 2017

Automated Quantification of Subcellular Structures in the RPE: Lipid Droplets, Autophagic Vacuoles, and Lipofuscin

Feriel K. Presswalla; Qitao Zhang; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1041. doi:

ARVO Annual Meeting Abstract June 2017

Lipid Handling by RPE Predicts Certain Features of Age-Related Macular Degeneration

Qitao Zhang; Feriel K. Presswalla; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2293. doi:

ARVO Annual Meeting Abstract September 2016

A primary retinal pigment epithelial culture model for evaluating therapeutic targets in dry macular degeneration

Qitao Zhang; Feriel Presswalla; Carol Charniga; Jeffrey Stern; Sally Temple; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5015. doi:

ARVO Annual Meeting Abstract June 2015

Evaluating Retinal Pigment Epithelium Cultures for Establishing Automated, Live-Cell Tracking of Outer Segment Degradation

Jason Miller; Qitao Zhang; Steve Rowe; Daniel Peisach; David N Zacks; Sami Barmada; Debra A Thompson

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4225. doi:

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