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ARVO Annual Meeting Abstract June 2024

Ile-Trp dipeptide prevents diabetic retinopathy via gut Indole/AhR/PXR signaling in type 2 diabetes

Ram Prasad; Yvonne Adu-Agyeiwaah; Edgar L Ready V; Sarbodeep Paul; Rati Sharma; Iuliia Dorofeeva; Jason Floyd; Aayush Rohella; Sergio Li Calzi; Bruce Stevens; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):844.

ARVO Annual Meeting Abstract June 2024

An engineered probiotic expressing Ang1-7 minimizes the risk of developing diabetic retinopathy in db/db mice

Sarbodeep Paul; Ram Prasad; Yvonne Adu-Agyeiwaah; Edgar L Ready V; Rati Sharma; Iuliia Dorofeeva; Jason Floyd; Aayush Rohella; Sergio Li Calzi; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):323.

ARVO Annual Meeting Abstract June 2023

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Ram Prasad; Jason Floyd; Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Sergio Li Calzi; Dibyendu Chakraborty; Angela Harbour; Aayush Rohella; Irina A Pikuleva; Julia V. Busik; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):938.

ARVO Annual Meeting Abstract June 2022

Maintenance of intestinal ACE2 minimizes the risk of developing diabetic retinopathy in type 1 diabetes

Ram Prasad; Jason Floyd; Bright Asare-Bediako; Dibyendu Chakraborty; Yvonne Adu-Agyeiwaah; Angela Harbour; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2309.

Articles December 2020

Angiotensin-(1–7) Expressed From Lactobacillus Bacteria Protect Diabetic Retina in Mice

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Amrisha Verma; Ping Zhu; Kang Xu; Tao Du; Shengquan Liao; Zhibing Liang; Mohan K. Raizada; Qiuhong Li

Trans. Vis. Sci. Tech.. 2020; 9(13):20. https://doi.org/10.1167/tvst.9.13.20

ARVO Annual Meeting Abstract June 2020

Oral administration of engineered probiotic prevents gut dysbiosis in type 1 diabetes and alleviates diabetic retinopathy (DR)

Ram Prasad; Jason L. Floyd; DIBYENDU CHAKRABORTY; Bright Asare-Bediako; Yvonne Adu-Agyeiwaah; Sergio Li Calzi; Robert F. Rosencrans; Chao Huang; Mariana DuPont; Sunil K Noothi; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1169.

ARVO Annual Meeting Abstract June 2017

Gene Therapy with the Caspase Activation and Recruitment Domain (CARD) Slows the Retina Degeneration of the Sod2 Knock-Out Mouse Model of Geographic Atrophy

Cristhian J Ildefonso; Brianna M Bowman; Manas Ranjan Biswal; Chulbul M Ahmed; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3387.

ARVO Annual Meeting Abstract June 2017

Genetically modified probiotics for oral delivery of Angiotensin-(1-7) confers protection against diabetic complications

Qiuhong Li; Zhibing Liang; Kang Xu; Tao Du; Ping Zhu; Tuhina Prasad; Shenquan Liao; Manoj Kulkarni; Amrisha Verma; Mohan Raizada

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4049.

ARVO Annual Meeting Abstract June 2017

Oral delivery of Angiotensin-(1-7) bioencapsulated in plant cells protect against diabetes-induced retinopathy and other complications

Amrisha Verma; Kang Xu; Tao Du; Manoj Kulkarni; Ping Zhu; Tuhina Prasad; Henry Daniell; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5213.

Physiology and Pharmacology December 2016

Beneficial Effects of Combined AT 1 Receptor/Neprilysin Inhibition (ARNI) Versus AT 1 Receptor Blockade Alone in the Diabetic Eye

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Tuhina Prasad; Lodi C. W. Roksnoer; Ping Zhu; Amrisha Verma; Yiming Li; Wendy W. Batenburg; René de Vries; A. H. Jan Danser; Qiuhong Li
TAGS: diabetes mellitus, diabetic retinopathy, neprilysin, eye, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6722-6730. https://doi.org/10.1167/iovs.16-20289

ARVO Annual Meeting Abstract September 2016

Beneficial effects of combined AT1 receptor/neprilysin inhibition (ARNI) versus AT1 receptor blockade alone in the diabetic eye

Qiuhong Li; Lodi Roksnoer; Tuhina Prasad; Ping Zhu; Amrisha Verma; Wendy Batenburg; Rene de Vries; A.H. Jan Danser

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2712.

ARVO Annual Meeting Abstract September 2016

Induction of Endogenous Nrf2 Activation in the Retina Partially Protects from Oxidative Stress and Inflammation

Cristhian J Ildefonso; Emily E Brown; Ryo Iwata; Chulbul M Ahmed; Michael Massengill; Manas Biswal; Shannon Elizabeth Boye; William W Hauswirth; John Ash; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5399.

ARVO Annual Meeting Abstract September 2016

Reduced Optic Atrophy 1 (OPA1) gene expression in diabetic retina- implication of mitochondrial dynamics in pathogenesis of diabetic retinopathy.

Amrisha Verma; Ping Zhu; Tuhina Prasad; Zhibing Liang; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5446.

ARVO Annual Meeting Abstract September 2016

Expression of repressor element 1-silencing transcription factor (REST) gene in rodent and human retina- implication in AMD

Tuhina Prasad; Amrisha Verma; Ping Zhu; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5801.

Biochemistry and Molecular Biology February 2016

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide

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Cristhian J. Ildefonso; Henrique Jaime; Emily E. Brown; Ryo L. Iwata; Chulbul M. Ahmed; Michael T. Massengill; Manas R. Biswal; Shannon E. Boye; William W. Hauswirth; John D. Ash; Qiuhong Li; Alfred S. Lewin
TAGS: genes, mice, peptides, retina, signal pathway, signal transduction pathways, spatial vectors, oxidative stress, polymerase chain reaction, proteins
Invest. Ophthalmol. Vis. Sci.. 2016; 57(2):372-386. https://doi.org/10.1167/iovs.15-17703

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Downregulating p22phox ameliorates inflammation in Angiotensin II induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

Yiguo Qiu; Lifei Tao; Peizeng Yang; Qiuhong Li; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):839.

ARVO Annual Meeting Abstract June 2015

Delivery of the Anti-inflammatory CARD Gene Allows Retinal Recovery After Acute Oxidative Injury: Implications for AMD

Cristhian J Ildefonso; Henrique Jaime; Kyle Jones; Manas Ranjan Biswal; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1089.

ARVO Annual Meeting Abstract June 2015

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

William W Hauswirth; Rachel M Stupay; Ping Zhu; Wen-Tao Deng; Vince Chiodo; Sanford L Boye; Qiuhong Li; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3630.

ARVO Annual Meeting Abstract June 2015

Increased levels of amyloid β peptides in RPE via AAV-mediated gene transfer mimics AMD-like pathology in mice

Tuhina Prasad; Ping Zhu; Amrisha Verma; Paramita Chakrabarty; Awilda M Rosario; Todd E Golde; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3765.

Retina June 2014

Angiotensin-Converting Enzyme 2 (ACE2) Activator Diminazene Aceturate Ameliorates Endotoxin-Induced Uveitis in Mice

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Yiguo Qiu; Pollob Kumar Shil; Ping Zhu; Hongxia Yang; Amrisha Verma; Bo Lei; Qiuhong Li
TAGS: angiotensin-converting enzyme, cytokine, diminazene, endotoxins, inflammation, inflammatory cells, mice, transcriptional activation, uveitis, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3809-3818. https://doi.org/10.1167/iovs.14-13883

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Ile-Trp dipeptide prevents diabetic retinopathy via gut Indole/AhR/PXR signaling in type 2 diabetes

An engineered probiotic expressing Ang1-7 minimizes the risk of developing diabetic retinopathy in db/db mice

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Maintenance of intestinal ACE2 minimizes the risk of developing diabetic retinopathy in type 1 diabetes

Angiotensin-(1–7) Expressed From Lactobacillus Bacteria Protect Diabetic Retina in Mice

Oral administration of engineered probiotic prevents gut dysbiosis in type 1 diabetes and alleviates diabetic retinopathy (DR)

Gene Therapy with the Caspase Activation and Recruitment Domain (CARD) Slows the Retina Degeneration of the Sod2 Knock-Out Mouse Model of Geographic Atrophy

Genetically modified probiotics for oral delivery of Angiotensin-(1-7) confers protection against diabetic complications

Oral delivery of Angiotensin-(1-7) bioencapsulated in plant cells protect against diabetes-induced retinopathy and other complications

Beneficial Effects of Combined AT 1 Receptor/Neprilysin Inhibition (ARNI) Versus AT 1 Receptor Blockade Alone in the Diabetic Eye

Beneficial effects of combined AT1 receptor/neprilysin inhibition (ARNI) versus AT1 receptor blockade alone in the diabetic eye

Induction of Endogenous Nrf2 Activation in the Retina Partially Protects from Oxidative Stress and Inflammation

Reduced Optic Atrophy 1 (OPA1) gene expression in diabetic retina- implication of mitochondrial dynamics in pathogenesis of diabetic retinopathy.

Expression of repressor element 1-silencing transcription factor (REST) gene in rodent and human retina- implication in AMD

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide

Downregulating p22phox ameliorates inflammation in Angiotensin II induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

Delivery of the Anti-inflammatory CARD Gene Allows Retinal Recovery After Acute Oxidative Injury: Implications for AMD

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

Increased levels of amyloid β peptides in RPE via AAV-mediated gene transfer mimics AMD-like pathology in mice

Angiotensin-Converting Enzyme 2 (ACE2) Activator Diminazene Aceturate Ameliorates Endotoxin-Induced Uveitis in Mice

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