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ARVO Annual Meeting Abstract June 2017

Gene Therapy with the Caspase Activation and Recruitment Domain (CARD) Slows the Retina Degeneration of the Sod2 Knock-Out Mouse Model of Geographic Atrophy

Cristhian J Ildefonso; Brianna M Bowman; Manas Ranjan Biswal; Chulbul M Ahmed; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3387. doi:

ARVO Annual Meeting Abstract June 2017

Genetically modified probiotics for oral delivery of Angiotensin-(1-7) confers protection against diabetic complications

Qiuhong Li; Zhibing Liang; Kang Xu; Tao Du; Ping Zhu; Tuhina Prasad; Shenquan Liao; Manoj Kulkarni; Amrisha Verma; Mohan Raizada

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4049. doi:

ARVO Annual Meeting Abstract June 2017

Oral delivery of Angiotensin-(1-7) bioencapsulated in plant cells protect against diabetes-induced retinopathy and other complications

Amrisha Verma; Kang Xu; Tao Du; Manoj Kulkarni; Ping Zhu; Tuhina Prasad; Henry Daniell; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5213. doi:

Physiology and Pharmacology December 2016

Beneficial Effects of Combined AT 1 Receptor/Neprilysin Inhibition (ARNI) Versus AT 1 Receptor Blockade Alone in the Diabetic Eye

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Tuhina Prasad; Lodi C. W. Roksnoer; Ping Zhu; Amrisha Verma; Yiming Li; Wendy W. Batenburg; René de Vries; A. H. Jan Danser; Qiuhong Li
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, neprilysin, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6722-6730. doi: 10.1167/iovs.16-20289

ARVO Annual Meeting Abstract September 2016

Reduced Optic Atrophy 1 (OPA1) gene expression in diabetic retina- implication of mitochondrial dynamics in pathogenesis of diabetic retinopathy.

Amrisha Verma; Ping Zhu; Tuhina Prasad; Zhibing Liang; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5446. doi:

ARVO Annual Meeting Abstract September 2016

Expression of repressor element 1-silencing transcription factor (REST) gene in rodent and human retina- implication in AMD

Tuhina Prasad; Amrisha Verma; Ping Zhu; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5801. doi:

ARVO Annual Meeting Abstract September 2016

Beneficial effects of combined AT1 receptor/neprilysin inhibition (ARNI) versus AT1 receptor blockade alone in the diabetic eye

Qiuhong Li; Lodi Roksnoer; Tuhina Prasad; Ping Zhu; Amrisha Verma; Wendy Batenburg; Rene de Vries; A.H. Jan Danser

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2712. doi:

ARVO Annual Meeting Abstract September 2016

Induction of Endogenous Nrf2 Activation in the Retina Partially Protects from Oxidative Stress and Inflammation

Cristhian J Ildefonso; Emily E Brown; Ryo Iwata; Chulbul M Ahmed; Michael Massengill; Manas Biswal; Shannon Elizabeth Boye; William W Hauswirth; John Ash; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5399. doi:

Biochemistry and Molecular Biology February 2016

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide

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Cristhian J. Ildefonso; Henrique Jaime; Emily E. Brown; Ryo L. Iwata; Chulbul M. Ahmed; Michael T. Massengill; Manas R. Biswal; Shannon E. Boye; William W. Hauswirth; John D. Ash; Qiuhong Li; Alfred S. Lewin
TAGS: oxidative stress, polymerase chain reaction, disease vectors, electroretinography, fluorescent antibody technique, genes, peptides, uveitis, eye, mice, proteins, retina, signal pathway, signal transduction pathways, spatial vectors
Invest. Ophthalmol. Vis. Sci.. 2016; 57(2):372-386. doi: 10.1167/iovs.15-17703

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Delivery of the Anti-inflammatory CARD Gene Allows Retinal Recovery After Acute Oxidative Injury: Implications for AMD

Cristhian J Ildefonso; Henrique Jaime; Kyle Jones; Manas Ranjan Biswal; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1089. doi:

ARVO Annual Meeting Abstract June 2015

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

William W Hauswirth; Rachel M Stupay; Ping Zhu; Wen-Tao Deng; Vince Chiodo; Sanford L Boye; Qiuhong Li; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3630. doi:

ARVO Annual Meeting Abstract June 2015

Increased levels of amyloid β peptides in RPE via AAV-mediated gene transfer mimics AMD-like pathology in mice

Tuhina Prasad; Ping Zhu; Amrisha Verma; Paramita Chakrabarty; Awilda M Rosario; Todd E Golde; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3765. doi:

ARVO Annual Meeting Abstract June 2015

Downregulating p22phox ameliorates inflammation in Angiotensin II induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

Yiguo Qiu; Lifei Tao; Peizeng Yang; Qiuhong Li; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):839. doi:

Retina June 2014

Angiotensin-Converting Enzyme 2 (ACE2) Activator Diminazene Aceturate Ameliorates Endotoxin-Induced Uveitis in Mice

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Yiguo Qiu; Pollob Kumar Shil; Ping Zhu; Hongxia Yang; Amrisha Verma; Bo Lei; Qiuhong Li
TAGS: cytokine, endotoxins, inflammatory cell, angiotensin-converting enzyme, inflammation, anterior chamber of eye, diminazene, uveitis, vitreous body, eye, mice, transcriptional activation, normal saline, saline solution, eye inflammation
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3809-3818. doi: 10.1167/iovs.14-13883

ARVO Annual Meeting Abstract April 2014

Suppression of ocular inflammation by a combination of renin inhibitor and prorenin receptor blocker

Qiuhong Li; Pollob Kumar Shil; Amrisha Verma; Ping Zhu; Jan A Danser; Wendy W Batenburg

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6295. doi:

ARVO Annual Meeting Abstract April 2014

Oral Delivery of ACE2 or Ang-(1-7) Bioencapsulated in Plant Cells Protect against Experimental Uveitis and Autoimmune Uveoretinitis

Pollob Kumar Shil; Kwangchul Kwon; Ping Zhu; Amrisha Verma; Vinayak Shenoy; Mohan Raizada; Henry Daniell; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5999. doi:

ARVO Annual Meeting Abstract April 2014

The neuroprotection of Angiotensin-(1-7) in Tg(RHO P347S) and rd10 mice

Ping Zhu; Pollob Kumar Shil; Wen-tao Deng; Jie Li; Amrisha Verma; Tuhina Prasad; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6187. doi:

ARVO Annual Meeting Abstract April 2014

Gene Therapy with the Caspase Activation and Recruitment Domain (CARD) Reduced Inflammation in the Endotoxin Induced Uveitis (EIU) Mouse Model

Cristhian J Ildefonso; Henrique Jaime; Qiuhong Li; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3303. doi:

ARVO Annual Meeting Abstract April 2014

Using the M013 Myxoma Virus Gene to Target the Inflammasome in the Retina

Henrique Jaime; Cristhian J Ildefonso; Mohammed M Rahman; Qiuhong Li; Grant McFadden; Alfred S Lewin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3322. doi:

ARVO Annual Meeting Abstract April 2014

Optimization of Clarin-1 AAV Gene Delivery Vectors to the Mouse Retina

Rachel M Stupay; Ping Zhu; Wen-tao Deng; Vince Chiodo; Sanford L Boye; Qiuhong Li; William W Hauswirth; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3324. doi:

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Gene Therapy with the Caspase Activation and Recruitment Domain (CARD) Slows the Retina Degeneration of the Sod2 Knock-Out Mouse Model of Geographic Atrophy

Genetically modified probiotics for oral delivery of Angiotensin-(1-7) confers protection against diabetic complications

Oral delivery of Angiotensin-(1-7) bioencapsulated in plant cells protect against diabetes-induced retinopathy and other complications

Beneficial Effects of Combined AT 1 Receptor/Neprilysin Inhibition (ARNI) Versus AT 1 Receptor Blockade Alone in the Diabetic Eye

Reduced Optic Atrophy 1 (OPA1) gene expression in diabetic retina- implication of mitochondrial dynamics in pathogenesis of diabetic retinopathy.

Expression of repressor element 1-silencing transcription factor (REST) gene in rodent and human retina- implication in AMD

Beneficial effects of combined AT1 receptor/neprilysin inhibition (ARNI) versus AT1 receptor blockade alone in the diabetic eye

Induction of Endogenous Nrf2 Activation in the Retina Partially Protects from Oxidative Stress and Inflammation

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide

Delivery of the Anti-inflammatory CARD Gene Allows Retinal Recovery After Acute Oxidative Injury: Implications for AMD

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

Increased levels of amyloid β peptides in RPE via AAV-mediated gene transfer mimics AMD-like pathology in mice

Downregulating p22phox ameliorates inflammation in Angiotensin II induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

Angiotensin-Converting Enzyme 2 (ACE2) Activator Diminazene Aceturate Ameliorates Endotoxin-Induced Uveitis in Mice

Suppression of ocular inflammation by a combination of renin inhibitor and prorenin receptor blocker

Oral Delivery of ACE2 or Ang-(1-7) Bioencapsulated in Plant Cells Protect against Experimental Uveitis and Autoimmune Uveoretinitis

The neuroprotection of Angiotensin-(1-7) in Tg(RHO P347S) and rd10 mice

Gene Therapy with the Caspase Activation and Recruitment Domain (CARD) Reduced Inflammation in the Endotoxin Induced Uveitis (EIU) Mouse Model

Using the M013 Myxoma Virus Gene to Target the Inflammasome in the Retina

Optimization of Clarin-1 AAV Gene Delivery Vectors to the Mouse Retina

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