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Meeting Abstract (22)
Journal Articles (12)

Journal

Investigative Ophthalmology & Visual Science (34)

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ARVO Annual Meeting Abstract (22)
Articles (5)
Glaucoma (5)
Biochemistry and Molecular Biology (1)
Research Highlight (1)

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Eye Anatomy and Disorders (9)
Retina (8)
Glaucoma (7)
Genetics (6)
Biochemistry and Molecular Biology (4)
Visual Neuroscience (3)
Eye Injuries / Ocular Trauma (1)
Oncology (1)

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mice (5)
retinal ganglion cells (5)
glaucoma (4)
apoptosis (3)
ganglia (3)
optic nerve (3)
retina (3)
cercopithecidae (2)
eye (2)
genes (2)

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ARVO Annual Meeting Abstract June 2020

Bclx gene therapy prevents BAX activation and preserves retinal ganglion cell axons in the DBA/2J glaucoma model.

Ryan Donahue; Jenna R. Gustafson; Rachel Fehrman; Margaret Maes; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):659. doi:

ARVO Annual Meeting Abstract June 2020

Live Cell Imaging of BAX Recruitment in Retinal Ganglion Cells Reveals Characteristics of Anoikis

Robert W Nickells; Margaret E. Maes; Ryan Donahue; Jenna R. Gustafson; Donna M Peters

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4334. doi:

ARVO Annual Meeting Abstract July 2019

Exploring the Role of BAX in the Degeneration of Retinal Ganglion Cell Axons and Dendritic Arbors

Ryan Joseph Donahue; Briana N. Ebbinghaus; Mrinalini Hoon; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):651. doi:

Glaucoma December 2017

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

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Robert W. Nickells; Heather M. Schmitt; Margaret E. Maes; Cassandra L. Schlamp
TAGS: mice, optic nerve, optic nerve injuries, retina, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6091-6104. doi: https://doi.org/10.1167/iovs.17-22634

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Delayed RGC death and persistent JNK activation following optic nerve injury in BAX deficient mice

Ryan Donahue; Joshua Grosser; Margaret Maes; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2538. doi:

ARVO Annual Meeting Abstract June 2017

Overexpression of histone deacetylase 3 (HDAC3) induces apoptosis in differentiated retinal neurons

Heather M Schmitt; Cassandra Schlamp; Huan Yang; Lian-Wang Guo; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2539. doi:

ARVO Annual Meeting Abstract June 2017

Characteristics of AAV2 mediated gene transfer in retinas after optic nerve injury

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4081. doi:

ARVO Annual Meeting Abstract June 2017

A Retinal Ganglion Cell Targting and Protecting Intraocular Drug Delivery System Using Unimolecular Nanoparticles

Lianwang Guo; Lei Zhao; Guojun Chen; Jun Li; Yingmei Fu; Timur Mavlyutov; Annie Yao; Robert W Nickells; Shaoqin Gong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4109. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of the preservative effects of UW cold storage solution on mouse eyes harvested for whole eye transplants

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):706. doi:

ARVO Annual Meeting Abstract September 2016

Systemic dosing of an HDAC3-selective inhibitor prevents retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury

Heather M Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2554. doi:

ARVO Annual Meeting Abstract September 2016

Mechanisms of Retinal Ganglion Cell Survival in Zebrafish after Axon Injury

Jonathan Mikal Skarie; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2555. doi:

ARVO Annual Meeting Abstract September 2016

Comparison of Transcriptomes of Models of Optic Nerve Injury

Ryan Donahue; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4787. doi:

Research Highlight September 2015

The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy

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Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(10):6113. doi: https://doi.org/10.1167/iovs.15-17997

ARVO Annual Meeting Abstract June 2015

Small molecule inhibition of Histone Deacetylase 3 (HDAC3) reduces RGC damage and apoptosis induced by acute optic nerve injury

Heather Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2425. doi:

ARVO Annual Meeting Abstract June 2015

Pannexin 1 expression in macroglia modulates their activation after optic nerve crush

Caitlin Mac Nair; Cassandra Schlamp; Valery I Shestopalov; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4948. doi:

ARVO Annual Meeting Abstract June 2015

BAX Oligomerization Kinetics and its Role in Retinal Ganglion Cell Death

Margaret Maes; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4952. doi:

Glaucoma March 2013

Nuclear Atrophy of Retinal Ganglion Cells Precedes the Bax -Dependent Stage of Apoptosis

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Katherine T. Janssen; Caitlin E. Mac Nair; Joel A. Dietz; Cassandra L. Schlamp; Robert W. Nickells
TAGS: atrophy, ganglia, mice, optic nerve, retinal ganglion cells, apoptosis, retina
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1805-1815. doi: https://doi.org/10.1167/iovs.11-9310

Includes: Supplemental Content

Articles May 2012

The Cell and Molecular Biology of Glaucoma: Mechanisms of Retinal Ganglion Cell Death

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Robert W. Nickells
TAGS: ganglia, glaucoma, retinal ganglion cells, molecular biology, proteins
Invest. Ophthalmol. Vis. Sci.. 2012; 53(5):2476-2481. doi: https://doi.org/10.1167/iovs.12-9483h

Glaucoma April 2012

Hydrocortisone Stimulates Neurite Outgrowth from Mouse Retinal Explants by Modulating Macroglial Activity

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Kimberly A. Toops; Cynthia Berlinicke; Donald J. Zack; Robert W. Nickells
TAGS: hydrocortisone, mice, neurites, ciliary neurotrophic factor, glial fibrillary acidic protein
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2046-2061. doi: https://doi.org/10.1167/iovs.11-8646

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Development of a Mini-qPCR Array for Mouse Retinal Ganglion Cells using MIQE Guidelines

Heather R. Pelzel; Joel A. Dietz; Kimberly A. Toops; Michael Waclawski; Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3864. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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