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Glaucoma December 2017

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

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Robert W. Nickells; Heather M. Schmitt; Margaret E. Maes; Cassandra L. Schlamp
TAGS: optic nerve injuries, eye, mice, optic nerve, retina
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6091-6104. doi: 10.1167/iovs.17-22634

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Delayed RGC death and persistent JNK activation following optic nerve injury in BAX deficient mice

Ryan Donahue; Joshua Grosser; Margaret Maes; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2538. doi:

ARVO Annual Meeting Abstract June 2017

Overexpression of histone deacetylase 3 (HDAC3) induces apoptosis in differentiated retinal neurons

Heather M Schmitt; Cassandra Schlamp; Huan Yang; Lian-Wang Guo; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2539. doi:

ARVO Annual Meeting Abstract June 2017

Characteristics of AAV2 mediated gene transfer in retinas after optic nerve injury

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4081. doi:

ARVO Annual Meeting Abstract June 2017

A Retinal Ganglion Cell Targting and Protecting Intraocular Drug Delivery System Using Unimolecular Nanoparticles

Lianwang Guo; Lei Zhao; Guojun Chen; Jun Li; Yingmei Fu; Timur Mavlyutov; Annie Yao; Robert W Nickells; Shaoqin Gong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4109. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of the preservative effects of UW cold storage solution on mouse eyes harvested for whole eye transplants

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):706. doi:

ARVO Annual Meeting Abstract September 2016

Systemic dosing of an HDAC3-selective inhibitor prevents retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury

Heather M Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2554. doi:

ARVO Annual Meeting Abstract September 2016

Mechanisms of Retinal Ganglion Cell Survival in Zebrafish after Axon Injury

Jonathan Mikal Skarie; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2555. doi:

ARVO Annual Meeting Abstract September 2016

Comparison of Transcriptomes of Models of Optic Nerve Injury

Ryan Donahue; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4787. doi:

Research Highlight September 2015

The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy

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Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(10):6113-6113. doi: 10.1167/iovs.15-17997

ARVO Annual Meeting Abstract June 2015

Small molecule inhibition of Histone Deacetylase 3 (HDAC3) reduces RGC damage and apoptosis induced by acute optic nerve injury

Heather Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2425. doi:

ARVO Annual Meeting Abstract June 2015

Pannexin 1 expression in macroglia modulates their activation after optic nerve crush

Caitlin Mac Nair; Cassandra Schlamp; Valery I Shestopalov; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4948. doi:

ARVO Annual Meeting Abstract June 2015

BAX Oligomerization Kinetics and its Role in Retinal Ganglion Cell Death

Margaret Maes; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4952. doi:

Glaucoma March 2013

Nuclear Atrophy of Retinal Ganglion Cells Precedes the Bax -Dependent Stage of Apoptosis

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Katherine T. Janssen; Caitlin E. Mac Nair; Joel A. Dietz; Cassandra L. Schlamp; Robert W. Nickells
TAGS: apoptosis, atrophy, ganglia, retinal ganglion cells, mice, optic nerve, retina
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1805-1815. doi: 10.1167/iovs.11-9310

Includes: Supplemental Content

Articles May 2012

The Cell and Molecular Biology of Glaucoma: Mechanisms of Retinal Ganglion Cell Death

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Robert W. Nickells
TAGS: glaucoma, ganglia, molecular biology, retinal ganglion cells, proteins
Invest. Ophthalmol. Vis. Sci.. 2012; 53(5):2476-2481. doi: 10.1167/iovs.12-9483h

Glaucoma April 2012

Hydrocortisone Stimulates Neurite Outgrowth from Mouse Retinal Explants by Modulating Macroglial Activity

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Kimberly A. Toops; Cynthia Berlinicke; Donald J. Zack; Robert W. Nickells
TAGS: hydrocortisone, ciliary neurotrophic factor, glial fibrillary acidic protein, neurites, mice
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2046-2061. doi: 10.1167/iovs.11-8646

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Development of a Mini-qPCR Array for Mouse Retinal Ganglion Cells using MIQE Guidelines

Heather R. Pelzel; Joel A. Dietz; Kimberly A. Toops; Michael Waclawski; Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3864. doi:

ARVO Annual Meeting Abstract March 2012

Attenuated Glial Activation After Optic Nerve Crush In Bax-deficient Mice

Caitlin E. Mac Nair; Cassandra L. Schlamp; Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3871. doi:

Glaucoma March 2012

Silencing of Fem1c R3 Gene Expression in the DBA/2J Mouse Precedes Retinal Ganglion Cell Death and Is Associated with Histone Deacetylase Activity

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Heather R. Pelzel; Cassandra L. Schlamp; Michael Waclawski; Malissa K. Shaw; Robert W. Nickells
TAGS: gene expression, glaucoma, ganglia, histone deacetylase, histones, retinal ganglion cells, mice, optic nerve
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1428-1435. doi: 10.1167/iovs.11-8872

ARVO Annual Meeting Abstract April 2011

GFAP Expression Supports Neurite Outgrowth In Retinal Explants

Kimberly A. Toops; Albee Messing; Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1858. doi:

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AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

Delayed RGC death and persistent JNK activation following optic nerve injury in BAX deficient mice

Overexpression of histone deacetylase 3 (HDAC3) induces apoptosis in differentiated retinal neurons

Characteristics of AAV2 mediated gene transfer in retinas after optic nerve injury

A Retinal Ganglion Cell Targting and Protecting Intraocular Drug Delivery System Using Unimolecular Nanoparticles

Characterization of the preservative effects of UW cold storage solution on mouse eyes harvested for whole eye transplants

Systemic dosing of an HDAC3-selective inhibitor prevents retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury

Mechanisms of Retinal Ganglion Cell Survival in Zebrafish after Axon Injury

Comparison of Transcriptomes of Models of Optic Nerve Injury

The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy

Small molecule inhibition of Histone Deacetylase 3 (HDAC3) reduces RGC damage and apoptosis induced by acute optic nerve injury

Pannexin 1 expression in macroglia modulates their activation after optic nerve crush

BAX Oligomerization Kinetics and its Role in Retinal Ganglion Cell Death

Nuclear Atrophy of Retinal Ganglion Cells Precedes the Bax -Dependent Stage of Apoptosis

The Cell and Molecular Biology of Glaucoma: Mechanisms of Retinal Ganglion Cell Death

Hydrocortisone Stimulates Neurite Outgrowth from Mouse Retinal Explants by Modulating Macroglial Activity

Development of a Mini-qPCR Array for Mouse Retinal Ganglion Cells using MIQE Guidelines

Attenuated Glial Activation After Optic Nerve Crush In Bax-deficient Mice

Silencing of Fem1c R3 Gene Expression in the DBA/2J Mouse Precedes Retinal Ganglion Cell Death and Is Associated with Histone Deacetylase Activity

GFAP Expression Supports Neurite Outgrowth In Retinal Explants

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