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ARVO Annual Meeting Abstract June 2022

Retinal ganglion cell specific deletion of arginase-2 preserves visual function after optic nerve crush

Syed Adeel Zaidi; zhimin Xu; Tahira Lemtalsi; Abdelrahman Fouda; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):863. doi:

ARVO Annual Meeting Abstract June 2022

Sigma 1 Receptor (Sig1R) activation attenuates vasculopathy associated with Retinopathy of Prematurity (ROP)

Jing Wang; Haiyan Xiao; zhimin Xu; Ruth B Caldwell; Sylvia B Smith

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):784 – F0343. doi:

ARVO Annual Meeting Abstract June 2022

Investigation of the retinal metabolic function in type 1 diabetic Akita mice

Abdelrahman Fouda; Esraa Shosha; Luke Qin; Tahira Lemtalsi; Syed Adeel Zaidi; Modesto Antonio Rojas; zhimin xu; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3598 – A0053. doi:

ARVO Annual Meeting Abstract June 2022

Systemic Pegylated-Arginase 1 Treatment of db/db mice Attenuates Diabetic Retinopathy Progression

Katharine Leilani Bunch; Ammar Abdelrahman; Ruth B Caldwell; R. William Caldwell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3519. doi:

ARVO Annual Meeting Abstract June 2022

Adenosine receptor 2A-mediated HIF signaling enhances endothelial-to-mesenchymal transition (EndMT) and promotes subretinal fibrosis

Qiuhua Yang; Qian Ma; Xiaoxiao Mao; Akrit Sodhi; Ruth B Caldwell; Yuqing Huo

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1491. doi:

ARVO Annual Meeting Abstract June 2021

Role for Arg1 and Arg2 in Age-related Intraocular Pressure Homeostasis

Jingwen Cai; Hongfang Yu; Michelle Drewry; Daniel W Stamer; Robert W Caldwell; Ruth B Caldwell; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1492. doi:

ARVO Annual Meeting Abstract June 2021

Pegylated Arginase 1 as a Treatment for Acute Central Nervous System (CNS) Injury

Abdelrahman Fouda; Wael Eldahshan; Zhimin Xu; Tahira Lemtalsi; Esraa Shosha; Paul Ning-Man Cheng; S. Priya Narayanan; Robert W Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2999. doi:

ARVO Annual Meeting Abstract June 2021

Arginase Isoforms and Diabetic Retinopathy in the db/db Mouse

Katharine Leilani Bunch; Ruth B Caldwell; Robert W Caldwell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3031. doi:

ARVO Annual Meeting Abstract June 2021

Novel role of acyl-coenzyme A: cholesterol transferase (ACAT1) in ischemic retinopathy

Modesto Antonio Rojas; Tahira Lemtalsi; Isabella Santana; Robert W Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3015. doi:

ARVO Annual Meeting Abstract June 2020

Development of pegylated arginase 1 as a therapy for retinal ischemic injury

Abdelrahman Y. Fouda; Zhimin Xu; Esraa Shosha; Paul Ning-Man Cheng; S. Priya Narayanan; Robert W Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4052. doi:

ARVO Annual Meeting Abstract June 2020

Treatment with spermine oxidase inhibitor ameliorates retinal neuronal and optic nerve degeneration in a mouse model of Multiple Sclerosis

S. Priya Narayanan; Fang Liu; Chithra D Palani; Abdelrahman Y. Fouda; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5186. doi:

ARVO Annual Meeting Abstract June 2020

Role of acyl-coenzyme A: cholesterol transferase (ACAT1) in pathological angiogenesis

Modesto Antonio Rojas; Isabella Santana; Tahira Lemtalsi; William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5408. doi:

ARVO Annual Meeting Abstract June 2020

Sigma 1 Receptor (Sig1R) activation: a novel therapy for neurovascular injury in Retinopathy of Prematurity (ROP)

Jing Wang; Haiyan Xiao; Zhimin Xu; Ruth B Caldwell; Sylvia B Smith

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5411. doi:

Retina March 2020

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse

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Abdelrahman Y. Fouda; Zhimin Xu; S. Priya Narayanan; R. William Caldwell; Ruth B. Caldwell
TAGS: adult, brain, mice, retina, diagnostic imaging, microglia, neurons
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):51. doi: https://doi.org/10.1167/iovs.61.3.51

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2019

Targeting neurovascular injury: Arginase 1 promotes angiogenic repair and limits neurodegeneration

Ruth B Caldwell; Abdelrahman Y Fouda; Zhimin Xu; Jutamas Suwanpradid; Modesto Rojas; Esraa Shosha; Chintan Patel; Ji Xing; S. Priya Narayanan; Robert W. Caldwell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3258. doi:

Retina May 2018

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

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Hanfang Zhang; Farlyn Z. Hudson; Zhimin Xu; Rebekah Tritz; Modesto Rojas; Chintan Patel; Stephen B. Haigh; Zsuzsanna Bordán; David A. Ingram; David J. Fulton; Neal L. Weintraub; Ruth B. Caldwell; Brian K. Stansfield
TAGS: endothelial cells, neovascularization, pathologic, neurofibromatosis type 1 protein, retinal neovascularization, vascular endothelial growth factor a, mice, oxygen, hypoxia, proto-oncogene proteins c-akt, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2520-2528. doi: https://doi.org/10.1167/iovs.17-22588

ARVO Annual Meeting Abstract June 2017

TREM-1 blockade prevents vitreoretinal neovascularization in a mouse model of retinopathy of prematurity

Modesto Antonio Rojas; Ruth B Caldwell; Zu Shen; Alexander Sigalov

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3452. doi:

ARVO Annual Meeting Abstract June 2017

Overexpression of spermine oxidase in retinal neurons aggravates vascular injury in a model of retinopathy of prematurity

Chintan Patel; PRAHALATHAN PICHAVARAM; Manuela Cervelli; Ruth B Caldwell; S. Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3463. doi:

ARVO Annual Meeting Abstract June 2017

Protective Role of Arginase 1 in Retinal Ischemia Reperfusion Injury

Abdelrahman Fouda; Zhimin Xu; Esraa Shosha; William Caldwell; S. Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5895. doi:

ARVO Annual Meeting Abstract June 2017

Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration

Ruth B Caldwell; Zhimin Xu; S. Priya Narayanan; Tahira Lemtalsi; Chintan Patel; Esraa Shosha; William Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1760. doi:

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Retinal ganglion cell specific deletion of arginase-2 preserves visual function after optic nerve crush

Sigma 1 Receptor (Sig1R) activation attenuates vasculopathy associated with Retinopathy of Prematurity (ROP)

Investigation of the retinal metabolic function in type 1 diabetic Akita mice

Systemic Pegylated-Arginase 1 Treatment of db/db mice Attenuates Diabetic Retinopathy Progression

Adenosine receptor 2A-mediated HIF signaling enhances endothelial-to-mesenchymal transition (EndMT) and promotes subretinal fibrosis

Role for Arg1 and Arg2 in Age-related Intraocular Pressure Homeostasis

Pegylated Arginase 1 as a Treatment for Acute Central Nervous System (CNS) Injury

Arginase Isoforms and Diabetic Retinopathy in the db/db Mouse

Novel role of acyl-coenzyme A: cholesterol transferase (ACAT1) in ischemic retinopathy

Development of pegylated arginase 1 as a therapy for retinal ischemic injury

Treatment with spermine oxidase inhibitor ameliorates retinal neuronal and optic nerve degeneration in a mouse model of Multiple Sclerosis

Role of acyl-coenzyme A: cholesterol transferase (ACAT1) in pathological angiogenesis

Sigma 1 Receptor (Sig1R) activation: a novel therapy for neurovascular injury in Retinopathy of Prematurity (ROP)

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse

Targeting neurovascular injury: Arginase 1 promotes angiogenic repair and limits neurodegeneration

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

TREM-1 blockade prevents vitreoretinal neovascularization in a mouse model of retinopathy of prematurity

Overexpression of spermine oxidase in retinal neurons aggravates vascular injury in a model of retinopathy of prematurity

Protective Role of Arginase 1 in Retinal Ischemia Reperfusion Injury

Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration

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