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ARVO Annual Meeting Abstract June 2023

Sustained reduction of intraocular pressure in mouse models of ocular hypertension following intraocular and periocular injection of an adeno-associated virus engineered to express Stanniocalcin-1

Kjersten Anderson; Uttio Roy Chowdhury; Tommy A Rinkoski; Michael P Fautsch; Gavin Roddy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3492.

ARVO Annual Meeting Abstract June 2023

Intraocular pressure regulation by dopamine receptors

Uttio Roy Chowdhury; Muhammad Abidi; Kjersten J Anderson; Michael P Fautsch

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3465.

Retina August 2022

Effects of Sleep Deprivation, Non-Dominant Hand Employment, Caffeine and Alcohol Intake During Surgical Performance: Lessons Learned From the Retina Eyesi Virtual Reality Surgical Simulator

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Feisal A. Adatia; Gerardo González-Saldivar; David R. Chow
TAGS: alcohol drinking, caffeine, ethanol, hand, hand surgery, retina, simulators, sleep deprivation, surgical procedures, operative, virtual reality
Trans. Vis. Sci. Tech.. 2022; 11(8):16. https://doi.org/10.1167/tvst.11.8.16

ARVO Annual Meeting Abstract June 2022

Effect of the ATP-sensitive potassium channel opener diazoxide on retinal vessel diameter of C57BL/6J mice

Uttio Roy Chowdhury; Michael P Fautsch

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3117.

Glaucoma April 2022

Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (K ATP ) Channel Opening Prodrug

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Cynthia L. Pervan-Steel; Uttio Roy Chowdhury; Hemchand K. Sookdeo; Ralph A. Casale; Peter I. Dosa; Thurein M. Htoo; Michael P. Fautsch; Barbara M. Wirostko
TAGS: intraocular pressure, potassium, prodrugs, body tissue, mice, phosphoric monoester hydrolases
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):26. https://doi.org/10.1167/iovs.63.4.26

Glaucoma February 2022

Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models

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Uttio Roy Chowdhury; J. Cameron Millar; Bradley H. Holman; Kjersten J. Anderson; Peter I. Dosa; Gavin W. Roddy; Michael P. Fautsch
TAGS: animal model, intraocular pressure, mice, ocular hypertension, diazoxide, katp channels, eye, steroids
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):15. https://doi.org/10.1167/iovs.63.2.15

Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

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Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. https://doi.org/10.1167/iovs.63.2.12

ARVO Annual Meeting Abstract June 2021

Prevalence of diabetic macular edema diagnosed with optical coherence tomography in patients with diabetes: a systematic review and meta-analysis

Peng Yan; James Im; Ronald Chow; Yaping Jin

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1143.

ARVO Annual Meeting Abstract June 2021

Ocular Tissue Conversion and Activity Profile of QLS-101, a Novel Topical IOP-Lowering Therapeutic

Cynthia Steel; Hemchand K. Sookdeo; Thurein Htoo; Ralph Casale; Uttio Roy Chowdhury; Michael P Fautsch; Barbara M Wirostko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2755.

ARVO Annual Meeting Abstract June 2021

Systemic and Ocular Toxicology and Pharmacokinetic Profiles of QLS-101, a Novel Topical IOP-Lowering Therapeutic

Barbara M Wirostko; Hemchand K. Sookdeo; Thurein Htoo; Ralph Casale; Uttio Roy Chowdhury; Michael P Fautsch; Cynthia Steel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2754.

Articles October 2020

Transgenic Expression of Cacna1f Rescues Vision and Retinal Morphology in a Mouse Model of Congenital Stationary Night Blindness 2A (CSNB2A)

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Derek M. Waldner; Kenichi Ito; Li-Li Chen; Lisa Nguyen; Robert L. Chow; Amy Lee; Derrick E. Rancourt; Francois Tremblay; William K. Stell; N. Torben Bech-Hansen
TAGS: animals, transgenic, language morphology, mice, morphology, night blindness, congenital stationary, pax6 transcription factor, retina, transgenes, vision
Trans. Vis. Sci. Tech.. 2020; 9(11):19. https://doi.org/10.1167/tvst.9.11.19

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Foveal avascular zone analysis in eyes following retinal detachment repair: a comparison between eyes with retinal displacement vs without displacement

Nishaant (Shaan) Bhambra; Samara B Marafon; Carolina Francisconi; Verena Juncal; Natalia Albuquerque Lucena Figueiredo; Louis Giavedoni; Alan Berger; Filiberto Altomare; David T Wong; David R Chow; Rajeev Hemant Muni

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4822.

ARVO Annual Meeting Abstract July 2019

Toxicity of Transition Metal Complex-based Nanophotoswitches in Retina

Lan Yue; Yi Shi; TAI-CHI LIN; Melanie Pribisko; Robert Grubbs; Harry Gray; Robert Chow; Mark Humayun

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4987.

ARVO Annual Meeting Abstract July 2019

Pharmacologic and safety profile of the ocular hypotensive agent cromakalim prodrug 1 (CKLP1), a novel ATP-sensitive potassium channel opener

Michael P Fautsch; Rachel Kudgus; Tommy Rinkoski; Cheryl Hann; Cindy Bahler; Bradley Holman; Joel Reid; Peter Dosa; Uttio Roy Chowdhury

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3772.

Biochemistry and Molecular Biology December 2018

Investigating the Pathogenicity of VSX1 Missense Mutations and Their Association With Corneal Disease

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Anastasia Marie Litke; Sarah Samuelson; Kerry R. Delaney; Yves Sauvé; Robert L. Chow
TAGS: cornea, corneal diseases, diagnostic imaging, mice, missense mutation, mutation, pathogenicity, keratoconus, luciferases, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5824-5835. https://doi.org/10.1167/iovs.18-25490

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Activity of iridium pyridine-based nanophotoswitches in retina

Lan Yue; Melanie Pribisko; Ming-yi Lin; Robert H Grubbs; Harry Gray; Robert H Chow; Mark S. Humayun

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3976.

ARVO Annual Meeting Abstract July 2018

Delivery and Toxicity of Ruthenium Pyridine-based Nanophotoswitches in Retina

Melanie Pribisko; Uli Herget; Lan Yue; Ming-yi Lin; Robert H Chow; Mark S. Humayun; Robert H Grubbs; Harry Gray

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):232.

ARVO Annual Meeting Abstract July 2018

Investigating the pathogenicity of missense mutations in VSX1 and their association with corneal dystrophies

Anastasia Marie Litke; Sarah Samuelson; Kerry Delaney; Yves Sauve; Robert L Chow

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2918.

Glaucoma November 2017

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

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Uttio Roy Chowdhury; Tommy A. Rinkoski; Cindy K. Bahler; J. Cameron Millar; Jacques A. Bertrand; Bradley H. Holman; Joseph M. Sherwood; Darryl R. Overby; Kristen L. Stoltz; Peter I. Dosa; Michael P. Fautsch
TAGS: antihypertensive agents, aqueous humor, combined modality therapy, cromakalim, eye, intraocular pressure, mice, oryctolagus cuniculus, prodrugs, perfusion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5731-5742. https://doi.org/10.1167/iovs.17-22538

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Pharmacologic profile and distribution of CKLP1, a novel prodrug of the ATP sensitive potassium channel opener levcromakalim, following various modes of administration

Uttio Roy Chowdhury; Rachel A Kudgus; Tommy A. Rinkoski; Joel M Reid; Michael P Fautsch

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4595.

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Sustained reduction of intraocular pressure in mouse models of ocular hypertension following intraocular and periocular injection of an adeno-associated virus engineered to express Stanniocalcin-1

Intraocular pressure regulation by dopamine receptors

Effects of Sleep Deprivation, Non-Dominant Hand Employment, Caffeine and Alcohol Intake During Surgical Performance: Lessons Learned From the Retina Eyesi Virtual Reality Surgical Simulator

Effect of the ATP-sensitive potassium channel opener diazoxide on retinal vessel diameter of C57BL/6J mice

Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (K ATP ) Channel Opening Prodrug

Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

Prevalence of diabetic macular edema diagnosed with optical coherence tomography in patients with diabetes: a systematic review and meta-analysis

Ocular Tissue Conversion and Activity Profile of QLS-101, a Novel Topical IOP-Lowering Therapeutic

Systemic and Ocular Toxicology and Pharmacokinetic Profiles of QLS-101, a Novel Topical IOP-Lowering Therapeutic

Transgenic Expression of Cacna1f Rescues Vision and Retinal Morphology in a Mouse Model of Congenital Stationary Night Blindness 2A (CSNB2A)

Foveal avascular zone analysis in eyes following retinal detachment repair: a comparison between eyes with retinal displacement vs without displacement

Toxicity of Transition Metal Complex-based Nanophotoswitches in Retina

Pharmacologic and safety profile of the ocular hypotensive agent cromakalim prodrug 1 (CKLP1), a novel ATP-sensitive potassium channel opener

Investigating the Pathogenicity of VSX1 Missense Mutations and Their Association With Corneal Disease

Activity of iridium pyridine-based nanophotoswitches in retina

Delivery and Toxicity of Ruthenium Pyridine-based Nanophotoswitches in Retina

Investigating the pathogenicity of missense mutations in VSX1 and their association with corneal dystrophies

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

Pharmacologic profile and distribution of CKLP1, a novel prodrug of the ATP sensitive potassium channel opener levcromakalim, following various modes of administration

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