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Articles December 2021

Topical Ketotifen Fumarate Inhibits Choroidal Mast Cell Degranulation and Loss of Retinal Pigment Epithelial Cells in Rat Model for Geographic Atrophy

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Tomohiro Nizawa; Imran A. Bhutto; Anupama Tiwari; Rhonda R. Grebe; Jesse Alt; Rana Rais; Malia M. Edwards; Gerard A. Lutty
TAGS: atrophy, choroid, electroretinography, eyedrops, gel, hydrogel, ketotifen, mast cell degranulation, mast-cell sarcoma, minimally conscious state
Trans. Vis. Sci. Tech.. 2021; 10(14):37. doi: https://doi.org/10.1167/tvst.10.14.37

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Topical Ketotifen fumarate inhibits mast cell degranulation and loss of retinal pigment epithelial cells in rat model for geographic atrophy

Tomohiro Niizawa; Imran Ahmed Bhutto; Anupama Tiwari; Rhonda R. Grebe; Jesse Alt; Rana Rais; Malia Michelle Edwards; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):252. doi:

ARVO Annual Meeting Abstract June 2020

Increased expression of epithelial-to-mesenchymal transition markers in geographic atrophy

Anupama Tiwari; Imran Ahmed Bhutto; Malia Michelle Edwards; Rhonda Grebe; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2273. doi:

ARVO Annual Meeting Abstract July 2019

Müller cell remodeling and phagocytosis in Choroidoremia

Malia Michelle Edwards; Rhonda Grebe; Rajkumar Baldeosingh; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4388. doi:

ARVO Annual Meeting Abstract July 2018

Understanding the role of glial cells (astrocytes and oligodendrocytes) in maintaining the homeostasis of the optic nerve

Meysam Yazdankhah; Rhonda Grebe; Emily G Baxi; Imran Ahmed Bhutto; Stacey L Hose; Amanda N. FairchildBaranowski; Peter Calabresi; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):311. doi:

ARVO Annual Meeting Abstract June 2017

Analysis of choriocapillaris ultrastructure in macular regions of eyes obtained from patients with neovascular AMD, geographic atrophy, and pure one and ten chromosomal abnormalities

Rhonda Grebe; Irum Mughal; William Bryden; Jing Tian; Malia Michelle Edwards; Scott McLeod; Gregory S Hageman; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2260. doi:

Retinal Cell Biology March 2017

Subretinal Glial Membranes in Eyes With Geographic Atrophy

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Malia M. Edwards; D. Scott McLeod; Imran A. Bhutto; Rhonda Grebe; Maeve Duffy; Gerard A. Lutty
TAGS: atrophic condition of skin, atrophy, embryonic lethal mutation, eye, neuroglia, retina, tissue membrane, vimentin, glial fibrillary acidic protein
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1352-1367. doi: https://doi.org/10.1167/iovs.16-21229

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Müller cell processes occupy the subretinal space in geographic atrophy and Stargardt disease.

Malia Michelle Edwards; D. Scott McLeod; Imran Ahmed Bhutto; Rhonda Grebe; Mercedes Villalonga; Vera L Bonilha; Joe G Hollyfield; Johanna M Seddon; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4191. doi:

ARVO Annual Meeting Abstract September 2016

Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells

Mallika Valapala; Abdulla Alamri; Rhonda Grebe; J Samuel Zigler; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6048. doi:

ARVO Annual Meeting Abstract September 2016

βA3/A1-crystallin is essential for autophagic lysosomal reformation (ALR) in the retinal pigmented epithelial (RPE) cells

Peng Shang; Mallika Valapala; Sayan Ghosh; Rhonda Grebe; Stacey L Hose; Imran Ahmed Bhutto; Gerard A Lutty; James T Handa; J Samuel Zigler; Guo-Tong Xu; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5006. doi:

Retinal Cell Biology April 2016

Albumen Transport to Bruch's Membrane and RPE by Choriocapillaris Caveolae

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Masataka Nakanishi; Rhonda Grebe; Imran A. Bhutto; Malia Edwards; D. Scott McLeod; Gerard A. Lutty
TAGS: albumins, biological transport, bruch's basal membrane, caveolae, chief complaint, mice, injections, serum albumin, bovine, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):2213-2224. doi: https://doi.org/10.1167/iovs.15-17934

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Caveolae transport of albumin by choriocapillaris from serum to Bruch’s membrane and RPE

Masataka Nakanishi; Imran Ahmed Bhutto; Rhonda Grebe; Malia Michelle Edwards; Scott D McLeod; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4460. doi:

ARVO Annual Meeting Abstract June 2013

βA3/A1-crystallin is essential for lysosome-mediated waste clearance in retinal pigmented epithelial (RPE) cells

Mallika Valapala; Christine Wilson; Imran Bhutto; Stacey Hose; Seth Greenbaum; Rhonda Grebe; James Handa; Lijin Dong; Eric Wawrousek; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1786. doi:

Cornea March 2013

L450W and Q455K Col8a2 Knock-In Mouse Models of Fuchs Endothelial Corneal Dystrophy Show Distinct Phenotypes and Evidence for Altered Autophagy

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Huan Meng; Mario Matthaei; Narendrakumar Ramanan; Rhonda Grebe; Shukti Chakravarti; Caroline L. Speck; Martha Kimos; Neeraj Vij; Charles G. Eberhart; Albert S. Jun
TAGS: autophagy, endothelium, mice, polymerase chain reaction, hereditary corneal dystrophy, corneal endothelium, phenotype, cornea, proteins, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1887-1897. doi: https://doi.org/10.1167/iovs.12-11021

Includes: Supplemental Content

Retinal Cell Biology December 2012

From Blood Islands to Blood Vessels: Morphologic Observations and Expression of Key Molecules during Hyaloid Vascular System Development

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D. Scott McLeod; Takuya Hasegawa; Takayuki Baba; Rhonda Grebe; Ines Galtier d'Auriac; Carol Merges; Malia Edwards; Gerard A. Lutty
TAGS: cd31 antigens, cxcr4 receptors, embryo, endothelial cells, erythroblasts, eye, hemangioblasts, hemoglobin, ki-67 antigen, molecule
Invest. Ophthalmol. Vis. Sci.. 2012; 53(13):7912-7927. doi: https://doi.org/10.1167/iovs.12-10140

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

Synergistic Effect of Two Independent Spontaneous Mutations on the Optic Nerve of the Rat

J S. Zigler, Jr.; C Zhang; R Grebe; S Hose; D Sinha

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2671. doi:

ARVO Annual Meeting Abstract April 2011

βA3/A1-crystallin: A New Protein Involved In Degradation Of Rod Outer Segments During Rpe Phagocytosis

Debasish Sinha; J S. Zigler, Jr.; Cheng Zhang; Rhonda Grebe; Yuri V. Sergeev; Donald J. Zack; James T. Handa; Gerard A. Lutty

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4786. doi:

ARVO Annual Meeting Abstract April 2011

Retinal Vascular Development Is Dependent On Retinal Ganglion Cells

Malia M. Edwards; D S. McLeod; Renzhong Li; Imran Bhutto; Rhonda Grebe; Xiuqian Mu; Gerard A. Lutty

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4840. doi:

ARVO Annual Meeting Abstract April 2011

L450W and Q455K Knock-In Mutations in the Col8a2 Gene Cause Fuchs Endothelial Corneal Dystrophy in the Mouse

Huan Meng; Mario Matthaei; Rhonda Grebe; Shukti Chakravarti; Albert Jun

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6600. doi:

ARVO Annual Meeting Abstract April 2011

Transfection of Human Corneas using Non-Viral Gene Carriers

Junko Yoshida; Qingguo Xu; Nick Boylan; Jung Soo Suk; Rhonda Grebe; Walter Stark; Justin Hanes; Gerard Lutty

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1412. doi:

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Topical Ketotifen Fumarate Inhibits Choroidal Mast Cell Degranulation and Loss of Retinal Pigment Epithelial Cells in Rat Model for Geographic Atrophy

Topical Ketotifen fumarate inhibits mast cell degranulation and loss of retinal pigment epithelial cells in rat model for geographic atrophy

Increased expression of epithelial-to-mesenchymal transition markers in geographic atrophy

Müller cell remodeling and phagocytosis in Choroidoremia

Understanding the role of glial cells (astrocytes and oligodendrocytes) in maintaining the homeostasis of the optic nerve

Analysis of choriocapillaris ultrastructure in macular regions of eyes obtained from patients with neovascular AMD, geographic atrophy, and pure one and ten chromosomal abnormalities

Subretinal Glial Membranes in Eyes With Geographic Atrophy

Müller cell processes occupy the subretinal space in geographic atrophy and Stargardt disease.

Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells

βA3/A1-crystallin is essential for autophagic lysosomal reformation (ALR) in the retinal pigmented epithelial (RPE) cells

Albumen Transport to Bruch's Membrane and RPE by Choriocapillaris Caveolae

Caveolae transport of albumin by choriocapillaris from serum to Bruch’s membrane and RPE

βA3/A1-crystallin is essential for lysosome-mediated waste clearance in retinal pigmented epithelial (RPE) cells

L450W and Q455K Col8a2 Knock-In Mouse Models of Fuchs Endothelial Corneal Dystrophy Show Distinct Phenotypes and Evidence for Altered Autophagy

From Blood Islands to Blood Vessels: Morphologic Observations and Expression of Key Molecules during Hyaloid Vascular System Development

Synergistic Effect of Two Independent Spontaneous Mutations on the Optic Nerve of the Rat

βA3/A1-crystallin: A New Protein Involved In Degradation Of Rod Outer Segments During Rpe Phagocytosis

Retinal Vascular Development Is Dependent On Retinal Ganglion Cells

L450W and Q455K Knock-In Mutations in the Col8a2 Gene Cause Fuchs Endothelial Corneal Dystrophy in the Mouse

Transfection of Human Corneas using Non-Viral Gene Carriers

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