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ARVO Annual Meeting Abstract September 2016

A2E adducts in the human retinal pigment epithelium

Masahiro Kono; Zsolt Ablonczy; Patrice W. Goletz; Joe G Hollyfield; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1737. doi:

ARVO Annual Meeting Abstract June 2015

Fluorescence and mass spectrometric imaging of monkey ( Cynomolgus) retinal pigment epithelium confirms the mismatching of lipofuscin and A2E distributions observed in human tissue

Patrick Pallitto; Zsolt Ablonczy; John E Donello; Yiannis Koutalos; Julia E Herrmann; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2352. doi:

ARVO Annual Meeting Abstract June 2015

Components of human lipofuscin

Masahiro Kono; John E. Oatis; Zsolt Ablonczy; Patrice W. Goletz; Joe G Hollyfield; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2381. doi:

ARVO Annual Meeting Abstract June 2015

Multimodal molecular imaging of Bruch’s membrane can predict age and macular degeneration

Hannah E Bowrey; E Ellen Jones; Mark Fields; Rosalie K Crouch; Lucian V Del Priore; Zsolt Ablonczy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3992. doi:

Biochemistry and Molecular Biology August 2013

Lack of Correlation Between the Spatial Distribution of A2E and Lipofuscin Fluorescence in the Human Retinal Pigment Epithelium

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Zsolt Ablonczy; Daniel Higbee; David M. Anderson; Mohammad Dahrouj; Angus C. Grey; Danielle Gutierrez; Yiannis Koutalos; Kevin L. Schey; Anne Hanneken; Rosalie K. Crouch
TAGS: fluorescence, lipofuscin, spectrometry, mass, matrix-assisted laser desorption-ionization, body tissue, eye, diagnostic imaging, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5535-5542. doi: https://doi.org/10.1167/iovs.13-12250

ARVO Annual Meeting Abstract March 2012

A2E and Lipofuscin Accumulation in the Retinal Pigment Epithelium of wild type and Abca4-deficient mice does not require Light Exposure

Nicholas Boyer; Daniel Higbee; Zsolt Ablonczy; Rosalie K. Crouch; Yiannis Koutalos

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3346. doi:

ARVO Annual Meeting Abstract March 2012

Linking Retinoids To Clinical Patterns Of Amd

Zsolt Ablonczy; Daniel Higbee; Anne M. Hanneken; Kevin L. Schey; Yiannis Koutalos; Rosalie K. Crouch

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6477. doi:

ARVO Annual Meeting Abstract March 2012

Acid Sphingomyelinase Deficiency Induces Age-related Degeneration In The Mouse Retina

Bill X. Wu; Jie Fan; Jenkins W. Jenkins; Yiannis Koutalos; Rosalie K. Crouch; Craig E. Crosson; Masahiro Kono; Yusuf A. Hannun

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6886. doi:

Multidisciplinary Ophthalmic Imaging June 2011

Spatial Localization of A2E in the Retinal Pigment Epithelium

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Angus C. Grey; Rosalie K. Crouch; Yiannis Koutalos; Kevin L. Schey; Zsolt Ablonczy
TAGS: body tissue, diagnostic imaging, fluorescence, lipofuscin, mice, pigment, retinal pigment epithelium, spectrometry, mass, matrix-assisted laser desorption-ionization, oxides, epithelium
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):3926-3933. doi: https://doi.org/10.1167/iovs.10-7020

Biochemistry and Molecular Biology May 2011

Rod Outer Segment Retinol Formation Is Independent of Abca4, Arrestin, Rhodopsin Kinase, and Rhodopsin Palmitylation

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Lorie R. Blakeley; Chunhe Chen; Ching-Kang Chen; Jeannie Chen; Rosalie K. Crouch; Gabriel H. Travis; Yiannis Koutalos
TAGS: arrestin, kinetics, rhodopsin, vitamin a, phosphotransferases, mice, rod outer segments
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3483-3491. doi: https://doi.org/10.1167/iovs.10-6694

Biochemistry and Molecular Biology May 2011

Rod Outer Segment Retinol Formation Is Independent of Abca4, Arrestin, Rhodopsin Kinase, and Rhodopsin Palmitylation

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Lorie R. Blakeley; Chunhe Chen; Ching-Kang Chen; Jeannie Chen; Rosalie K. Crouch; Gabriel H. Travis; Yiannis Koutalos
TAGS: arrestin, kinetics, rhodopsin, vitamin a, phosphotransferases, mice, rod outer segments
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3483-3491. doi: https://doi.org/10.1167/iovs.10-6694

ARVO Annual Meeting Abstract April 2011

Regulation of the Rate of Pigment Regeneration and its Relationship to Dark Adaptation and Recovery of Sensitivity in Vertebrate Photoreceptors

Rikard Frederiksen; Rosalie K. Crouch; Benjamin Nickle; Kaylan S. Chakrabarti; Carter Cornwall

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1179. doi:

ARVO Annual Meeting Abstract April 2011

Sensitive and Specific Mass Spectrometric Identification and Quantitation of A2E

Danielle B. Gutierrez; Dan Higbee; Kevin L. Schey; Rosalie K. Crouch; Zsolt Ablonczy

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):902. doi:

ARVO Annual Meeting Abstract April 2011

Rpe65 Is Present Within Human Cone Photoreceptors And Is Required For Efficient Cone Visual Pigment Regeneration

Peter H. Tang; Lee Wheless; Jian-Xing Ma; Rosalie K. Crouch

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3642. doi:

ARVO Annual Meeting Abstract April 2011

A2E And Lipofuscin Are Present In The Retinal Pigment Epithelium Of Nrl-/- Mice

Nicholas Boyer; Daniel Higbee; Lorie R. Blakeley; Zsolt Ablonczy; Rosalie K. Crouch; Yiannis Koutalos

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3645. doi:

ARVO Annual Meeting Abstract April 2011

Rpe65 Is Present Within The Inner Segments Of Cones In The Cone-dominant Retina, Suggesting Its Role In The Cone Visual Cycle

Rosalie K. Crouch; Jian-Xing Ma; Peter H. Tang

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3646. doi:

ARVO Annual Meeting Abstract April 2011

Accumulation Of A2E With 9-cis-Retinal Supplementation In Rpe65-/- Mice

Daniel Higbee; Danielle Gutierrez; Peter H. Tang; Yiannis Koutalos; Rosalie K. Crouch; Zsolt Ablonczy

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3647. doi:

ARVO Annual Meeting Abstract April 2011

Lipofuscin Does Not Correlate With A2E In The Human RPE

Zsolt Ablonczy; Dan Higbee; Danielle B. Gutierrez; David M. Anderson; Anne M. Hanneken; Yiannis Koutalos; Kevin L. Schey; Rosalie K. Crouch

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3916. doi:

Retina April 2011

Light Prevents Exogenous 11- cis Retinal from Maintaining Cone Photoreceptors in Chromophore-Deficient Mice

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Jie Fan; Rosalie K. Crouch; Masahiro Kono
TAGS: chromophore, mice, retinal cone, opsin
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2412-2416. doi: https://doi.org/10.1167/iovs.10-6437

Retina November 2010

Effective and Sustained Delivery of Hydrophobic Retinoids to Photoreceptors

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Peter H. Tang; Jie Fan; Patrice W. Goletz; Lee Wheless; Rosalie K. Crouch
TAGS: hydrophobicity, mice, photoreceptors, retinal cone, retinoids, retina, opsin
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5958-5964. doi: https://doi.org/10.1167/iovs.10-5766

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A2E adducts in the human retinal pigment epithelium

Fluorescence and mass spectrometric imaging of monkey ( Cynomolgus) retinal pigment epithelium confirms the mismatching of lipofuscin and A2E distributions observed in human tissue

Components of human lipofuscin

Multimodal molecular imaging of Bruch’s membrane can predict age and macular degeneration

Lack of Correlation Between the Spatial Distribution of A2E and Lipofuscin Fluorescence in the Human Retinal Pigment Epithelium

A2E and Lipofuscin Accumulation in the Retinal Pigment Epithelium of wild type and Abca4-deficient mice does not require Light Exposure

Linking Retinoids To Clinical Patterns Of Amd

Acid Sphingomyelinase Deficiency Induces Age-related Degeneration In The Mouse Retina

Spatial Localization of A2E in the Retinal Pigment Epithelium

Rod Outer Segment Retinol Formation Is Independent of Abca4, Arrestin, Rhodopsin Kinase, and Rhodopsin Palmitylation

Rod Outer Segment Retinol Formation Is Independent of Abca4, Arrestin, Rhodopsin Kinase, and Rhodopsin Palmitylation

Regulation of the Rate of Pigment Regeneration and its Relationship to Dark Adaptation and Recovery of Sensitivity in Vertebrate Photoreceptors

Sensitive and Specific Mass Spectrometric Identification and Quantitation of A2E

Rpe65 Is Present Within Human Cone Photoreceptors And Is Required For Efficient Cone Visual Pigment Regeneration

A2E And Lipofuscin Are Present In The Retinal Pigment Epithelium Of Nrl-/- Mice

Rpe65 Is Present Within The Inner Segments Of Cones In The Cone-dominant Retina, Suggesting Its Role In The Cone Visual Cycle

Accumulation Of A2E With 9-cis-Retinal Supplementation In Rpe65-/- Mice

Lipofuscin Does Not Correlate With A2E In The Human RPE

Light Prevents Exogenous 11- cis Retinal from Maintaining Cone Photoreceptors in Chromophore-Deficient Mice

Effective and Sustained Delivery of Hydrophobic Retinoids to Photoreceptors

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