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ARVO Annual Meeting Abstract June 2024

Peptide Therapy for Neuroprotection in Glaucoma

Dorota Luiza Stankowska; Gretchen Annika Johnson; Raghu R Krishnamoorthy; Ram H Nagaraj; Bindu Kodati

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1467.

ARVO Annual Meeting Abstract June 2024

CREB Activation by Mini-Chaperone Peptain-1-CPP (P1-CPP) Enhances Retinal Ganglion Cell Survival in an Acute Glaucoma Model

Gretchen Annika Johnson; Raghu R Krishnamoorthy; Ram H Nagaraj; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1243.

ARVO Annual Meeting Abstract June 2024

Assessment of Reconstituted High-Density Lipoprotein Nanoparticles for Ocular Delivery

Roland Max Petty; Rajiv Rangan; Nirupama Sabnis; Rafal Fudala; Andras G Lacko; Zygmunt Gryczynski; Raghu R Krishnamoorthy; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3975.

ARVO Annual Meeting Abstract June 2024

Temporal Dynamics of Endothelin-1 Mediated Changes in Mitochondrial Health and Retinal Ganglion Cell Death

Calvin David Brooks; Bindu Kodati; Dorota Luiza Stankowska; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3141.

ARVO Annual Meeting Abstract June 2023

Endothelin-1 Mediated Decrease in Mitochondrial Bioenergetics is Involved in Neurodegeneration of Retinal Ganglion Cells in a Rodent Model of Glaucoma

Bindu Kodati; Renuka Chaphalkar; Prabhavathi Maddineni; Dorota Luiza Stankowska; Gulab Zode; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2009.

ARVO Annual Meeting Abstract June 2023

P1-CPP promotes Foxo1 and Creb signaling and reduces apoptosis in Neurotrophic Factor-Deprived Primary Retinal Ganglion Cells

Gretchen A Johnson; Jennifer Hien Pham; Raghu R Krishnamoorthy; Ram H Nagaraj; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2005.

ARVO Annual Meeting Abstract June 2023

Intravitreal Endothelin-1 (ET-1) Injection Reduces Mitophagy in Retinal Ganglion Cells in MitoQC Mice

Calvin David Brooks; Bindu Kodati; Denise M Inman; Dorota Luiza Stankowska; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3497.

ARVO Annual Meeting Abstract June 2023

Endothelin-1 treatment produces mitochondrial damage in rat retinal ganglion cells.

Raghu R Krishnamoorthy; Bindu Kodati; Renuka M Chaphalkar; Calvin David Brooks; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3246.

ARVO Annual Meeting Abstract June 2022

The Endothelin Receptor Antagonist Macitentan Acts through both Vascular and Cellular Mechanisms to Promote Neuroprotection of Retinal Ganglion Cells in Rodents.

Raghu R Krishnamoorthy; Bindu Kodati; Sai H Chavala; Wei Zhang; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1484.

ARVO Annual Meeting Abstract June 2022

Endothelin-1 mediated decline in mitophagy in retinal ganglion cells contributes to neurodegeneration during ocular hypertension in rats

Bindu Kodati; Renuka M. Chaphalkar; Gretchen Annika Johnson; Dorota Luiza Stankowska; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2974 – F0215.

ARVO Annual Meeting Abstract June 2022

Mechanisms of Peptain-mediated Neuroprotection in Retinal Ganglion Cells

Gretchen Annika Johnson; Jennifer Hien Pham; Bindu Kodati; Raghu R Krishnamoorthy; Ram H Nagaraj; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2965 – F0206.

ARVO Annual Meeting Abstract June 2021

Cell Permeable Peptain for Neuroprotection in Glaucoma

Bindu Kodati; Vignesh Krishnamoorthy; Rooban B Nahomi; Mi-Hyun Nam; Renuka M Chaphalkar; Kallen J Beall; Ashley Kay Brodrick; Ram H Nagaraj; Raghu R Krishnamoorthy; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):229.

ARVO Annual Meeting Abstract June 2021

Endothelin-1 Mediated Decrease in Mitophagy is Involved in Neurodegeneration of Retinal Ganglion Cells in a Rodent Model of Glaucoma

Raghu R Krishnamoorthy; Renuka M Chaphalkar; Bindu Kodati; Shaoqing He; Dorota Luiza Stankowska

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3159.

Glaucoma May 2021

Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells

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Bindu Kodati; Dorota L. Stankowska; Vignesh R. Krishnamoorthy; Raghu R. Krishnamoorthy
TAGS: endothelin-1, glaucoma, mice, nerve degeneration, neuroprotection, phosphotransferases, retinal ganglion cells, immunohistochemistry, intravitreal injections
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):13. https://doi.org/10.1167/iovs.62.6.13

ARVO Annual Meeting Abstract June 2020

Endothelin-1 Induced Activation of Astrocytes and Changes in Their Subtype Markers

Shaoqing He; Vignesh Krishnamoorthy; Raghu R Krishnamoorthy; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):262.

ARVO Annual Meeting Abstract June 2020

Endothelin-1 Mediated Decrease in Mitochondrial Bioenergetics Involved in Neurodegeneration of Retinal Ganglion Cells

Renuka Chaphalkar; Dorota Luiza Stankowska; Shaoqing He; Nicole Phillips; Bindu Kodati; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):263.

ARVO Annual Meeting Abstract June 2020

Neuroprotective effects of SB203580 (p38 MAP kinase inhibitor) against Endothelin-1-induced retinal ganglion cell death

Vignesh Krishnamoorthy; Shaoqing He; Renuka Chaphalkar; Bindu Kodati; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4960.

ARVO Annual Meeting Abstract July 2019

Peptain-1 for neuroprotection in Glaucoma

Dorota L Stankowska; Mihyun Nam; Rooban Nahomi; Renuka Chaphalkar; Rafal Fudala; Raghu R Krishnamoorthy; Ram H Nagaraj

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):966.

ARVO Annual Meeting Abstract July 2019

Endothelin-1 Mediated Decrease in Expression of Mitochondrial Proteins ATP5H and COX17 in Retinal Ganglion Cells.

Renuka Chaphalkar; Dorota L Stankowska; Shaoqing He; Bindu Kodati; Raghu R Krishnamoorthy

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):24.

ARVO Annual Meeting Abstract July 2019

The Endothelin Receptor Antagonist Macitentan Attenuates Vasoconstrictive Effects of Endothelin-1 following Intravitreal Administration in Rodents

Raghu R Krishnamoorthy; Wei Zhang; Sai Chavala; Dorota L Stankowska

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):40.

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Peptide Therapy for Neuroprotection in Glaucoma

CREB Activation by Mini-Chaperone Peptain-1-CPP (P1-CPP) Enhances Retinal Ganglion Cell Survival in an Acute Glaucoma Model

Assessment of Reconstituted High-Density Lipoprotein Nanoparticles for Ocular Delivery

Temporal Dynamics of Endothelin-1 Mediated Changes in Mitochondrial Health and Retinal Ganglion Cell Death

Endothelin-1 Mediated Decrease in Mitochondrial Bioenergetics is Involved in Neurodegeneration of Retinal Ganglion Cells in a Rodent Model of Glaucoma

P1-CPP promotes Foxo1 and Creb signaling and reduces apoptosis in Neurotrophic Factor-Deprived Primary Retinal Ganglion Cells

Intravitreal Endothelin-1 (ET-1) Injection Reduces Mitophagy in Retinal Ganglion Cells in MitoQC Mice

Endothelin-1 treatment produces mitochondrial damage in rat retinal ganglion cells.

The Endothelin Receptor Antagonist Macitentan Acts through both Vascular and Cellular Mechanisms to Promote Neuroprotection of Retinal Ganglion Cells in Rodents.

Endothelin-1 mediated decline in mitophagy in retinal ganglion cells contributes to neurodegeneration during ocular hypertension in rats

Mechanisms of Peptain-mediated Neuroprotection in Retinal Ganglion Cells

Cell Permeable Peptain for Neuroprotection in Glaucoma

Endothelin-1 Mediated Decrease in Mitophagy is Involved in Neurodegeneration of Retinal Ganglion Cells in a Rodent Model of Glaucoma

Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells

Endothelin-1 Induced Activation of Astrocytes and Changes in Their Subtype Markers

Endothelin-1 Mediated Decrease in Mitochondrial Bioenergetics Involved in Neurodegeneration of Retinal Ganglion Cells

Neuroprotective effects of SB203580 (p38 MAP kinase inhibitor) against Endothelin-1-induced retinal ganglion cell death

Peptain-1 for neuroprotection in Glaucoma

Endothelin-1 Mediated Decrease in Expression of Mitochondrial Proteins ATP5H and COX17 in Retinal Ganglion Cells.

The Endothelin Receptor Antagonist Macitentan Attenuates Vasoconstrictive Effects of Endothelin-1 following Intravitreal Administration in Rodents

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