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Glaucoma August 2020

Increased Susceptibility to Glaucomatous Damage in Microfibril Deficient Mice

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Hang-Jing Wu; John Kuchtey; Rachel W. Kuchtey
TAGS: axon, disease susceptibility, fibrillin-1, glaucoma, injections, mice, microspheres, optic nerve, microfibrils, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):28. doi: https://doi.org/10.1167/iovs.61.10.28

Includes: Supplemental Content

Glaucoma May 2020

Telmisartan Reduces Axon Degeneration in Mice With Experimental Glaucoma

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Ralph J. Hazlewood; John Kuchtey; Hang-Jing Wu; Rachel W. Kuchtey
TAGS: axon, glaucoma, mice, neuroprotective effect, telmisartan, tissue degeneration, microspheres, intraocular pressure, injections
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):51. doi: https://doi.org/10.1167/iovs.61.5.51

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Telmisartan, an angiotensin II type 1 receptor blocker, reduces IOP and prevents axon loss in mice with experimental glaucoma

Ralph J Hazlewood; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):627. doi:

ARVO Annual Meeting Abstract July 2019

Reduced number and caliber of optic nerve axons and smaller optic nerves in mice homozygous for a glaucoma-causing mutation in Adamts10

Hangjing Wu; Rachel W Kuchtey; John Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2851. doi:

ARVO Annual Meeting Abstract July 2018

Increased susceptibility to glaucomatous optic nerve damage in microfibril deficient mice

Hangjing Wu; Abudi Nashabi; Frances Clark; Samyukta Reddy; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3705. doi:

ARVO Annual Meeting Abstract July 2018

Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study – Five-Year Findings

Thomas Mendel; Karen M Joos; Jeffrey Kammer; Rachel W Kuchtey; Edward Cherney; Stephen J Kim

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4428. doi:

ARVO Annual Meeting Abstract June 2017

Angiotensin II type 1 receptor blockers lower IOP in mice and reduce TGFβ signaling in retinal ganglion cells

Ralph J Hazlewood; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4917. doi:

ARVO Annual Meeting Abstract June 2017

Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma

Michelle Drewry; John Kuchtey; Iris Navarro; Shruti Sharma; W Daniel Stamer; Ashok Sharma; Pratap Challa; Rachel W Kuchtey; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2142. doi:

ARVO Annual Meeting Abstract June 2017

Glaucomatous retinal dysfunction and optic nerve phenotype in microfibril deficient mice

Hang Jing Wu; George Naratadam; Ralph Hazelwood; Abudi Nashabi; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5854. doi:

ARVO Annual Meeting Abstract September 2016

Inner Retina Dysfunction in Microfibril Deficient Mice with Low Tension Glaucoma

Hang-Jing Wu; Sayan Paria; George Naratadam; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2540. doi:

ARVO Annual Meeting Abstract September 2016

Association of miR-182 with High Tension Glaucoma

Yutao Liu; Jessica Cooke Bailey; Inas Helwa; W Daniel Stamer; Rachel W Kuchtey; R Rand Allingham; Michael A Hauser; Louis R Pasquale; Jonathan L Haines; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

The glaucoma-causative gene adamts10 is required for normal retinal ganglion cell development in zebrafish

John Kuchtey; Shu-Yu Wu; Frances K. Clark; Hassane S Mchaourab; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):810. doi:

ARVO Annual Meeting Abstract September 2016

Pharmacological investigations of angiotensin II type 1 receptor antagonists reveal effective physiological concentrations in the eye after administration via drinking water

Ralph J Hazlewood; George Naratadam; Sayan Paria; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1189. doi:

Genetics August 2016

A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium

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Yutao Liu; Jessica Cooke Bailey; Inas Helwa; W. Michael Dismuke; Jingwen Cai; Michelle Drewry; Murray H. Brilliant; Donald L. Budenz; William G. Christen; Daniel I. Chasman; John H. Fingert; Douglas Gaasterland; Terry Gaasterland; Mae O. Gordon; Robert P. Igo, Jr; Jae H. Kang; Michael A. Kass; Peter Kraft; Richard K. Lee; Paul Lichter; Sayoko E. Moroi; Anthony Realini; Julia E. Richards; Robert Ritch; Joel S. Schuman; William K. Scott; Kuldev Singh; Arthur J. Sit; Yeunjoo E. Song; Douglas Vollrath; Robert Weinreb; Felipe Medeiros; Gadi Wollstein; Donald J. Zack; Kang Zhang; Margaret A. Pericak-Vance; Pedro Gonzalez; W. Daniel Stamer; John Kuchtey; Rachel W. Kuchtey; R. Rand Allingham; Michael A. Hauser; Louis R. Pasquale; Jonathan L. Haines; Janey L. Wiggs
TAGS: micrornas, neighborhood, open-angle glaucoma, glaucoma, body tissue, hypertension, exosomes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4528-4535. doi: https://doi.org/10.1167/iovs.16-19688

Includes: Supplemental Content

Glaucoma July 2015

Metabolome-Wide Association Study of Primary Open Angle Glaucoma

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L. Goodwin Burgess; Karan Uppal; Douglas I. Walker; Rachel M. Roberson; ViLinh Tran; Megan B. Parks; Emily A. Wade; Alexandra T. May; Allison C. Umfress; Kelli L. Jarrell; Brooklyn O. C. Stanley; John Kuchtey; Rachel W. Kuchtey; Dean P. Jones; Milam A. Brantley, Jr
TAGS: metabolomics, open-angle glaucoma, metabolites
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):5020-5028. doi: https://doi.org/10.1167/iovs.15-16702

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study 24-Month Findings

Shriji Patel; Rohan Shah; Joshua Noren Carlson; Jeffrey Kammer; Rachel W Kuchtey; Karen M Joos; Edward F Cherney; Stephen J Kim

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4329. doi:

ARVO Annual Meeting Abstract June 2015

In search of novel CYP1B1 mutations that cause primary congenital glaucoma.

Varun Reddy; Sharon Freedman; Shelby Strickland; Yu Chen-Hsin; Rachel W Kuchtey; John Kuchtey; R Rand Allingham; Michael A Hauser

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2540. doi:

Glaucoma August 2014

Elevated Transforming Growth Factor β1 in Plasma of Primary Open-Angle Glaucoma Patients

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John Kuchtey; Jessica Kunkel; L. Goodwin Burgess; Megan B. Parks; Milam A. Brantley, Jr; Rachel W. Kuchtey
TAGS: open-angle glaucoma, plasma, transforming growth factor alpha, transforming growth factors, thrombospondin 1
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5291-5297. doi: https://doi.org/10.1167/iovs.14-14578

ARVO Annual Meeting Abstract April 2014

Calibration of TonoLab rebound tonometer is not affected by extremely thin corneas in microfibril deficient mice

Monique Michelle McCallister; Jessica Kunkel; John M Scichilone; John Kuchtey; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):138. doi:

ARVO Annual Meeting Abstract April 2014

Low tension glaucoma in microfibril deficient mice

John Kuchtey; Jessica Kunkel; Monique Michelle McCallister; John M Scichilone; Rachel W Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3804. doi:

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Increased Susceptibility to Glaucomatous Damage in Microfibril Deficient Mice

Telmisartan Reduces Axon Degeneration in Mice With Experimental Glaucoma

Telmisartan, an angiotensin II type 1 receptor blocker, reduces IOP and prevents axon loss in mice with experimental glaucoma

Reduced number and caliber of optic nerve axons and smaller optic nerves in mice homozygous for a glaucoma-causing mutation in Adamts10

Increased susceptibility to glaucomatous optic nerve damage in microfibril deficient mice

Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study – Five-Year Findings

Angiotensin II type 1 receptor blockers lower IOP in mice and reduce TGFβ signaling in retinal ganglion cells

Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma

Glaucomatous retinal dysfunction and optic nerve phenotype in microfibril deficient mice

Inner Retina Dysfunction in Microfibril Deficient Mice with Low Tension Glaucoma

Association of miR-182 with High Tension Glaucoma

The glaucoma-causative gene adamts10 is required for normal retinal ganglion cell development in zebrafish

Pharmacological investigations of angiotensin II type 1 receptor antagonists reveal effective physiological concentrations in the eye after administration via drinking water

A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium

Metabolome-Wide Association Study of Primary Open Angle Glaucoma

Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study 24-Month Findings

In search of novel CYP1B1 mutations that cause primary congenital glaucoma.

Elevated Transforming Growth Factor β1 in Plasma of Primary Open-Angle Glaucoma Patients

Calibration of TonoLab rebound tonometer is not affected by extremely thin corneas in microfibril deficient mice

Low tension glaucoma in microfibril deficient mice

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