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ARVO Annual Meeting Abstract June 2022

Metabolic analysis of serum deprived ARPE-19 cells -implications for cellular metabolic changes in age-related macular degeneration

Joanna Kempska; Kensuke Shima; Noriko Kubota; Paula Enzian; Svenja Rebecca Sonntag; Jan Rupp; Ralf Brinkmann; Salvatore Grisanti; Yoko Miura

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2482 – F0189. doi:

ARVO Annual Meeting Abstract June 2022

Fluorescence lifetime of ex-vivo retinal pigment epithelium in the state of enhanced mitochondrial uncoupling

Noriko Kubota; Joanna Kempska; Kensuke Shima; Paula Enzian; Svenja Rebecca Sonntag; Jan Rupp; Salvatore Grisanti; Ralf Brinkmann; Yoko Miura

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2471 – F0178. doi:

ARVO Annual Meeting Abstract June 2022

Towards thermal stimulation of the retina, RPE and choroid by temperature-controlled laser exposure

Christian Schmidt; Mario Mordmüller; Yoko Miura; Ralf Brinkmann

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3803 – F0224. doi:

ARVO Annual Meeting Abstract June 2022

Comparison between continuous wave and 10 kHz pulsed laser irradiation with regard to thermal damage on ex-vivo RPE explants

Alessa Hutfilz; Christopher Kren; Christian Schmidt; Dirk Theisen-Kunde; Mario Mordmüller; Yoko Miura; Ralf Brinkmann

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3802 – F0223. doi:

ARVO Annual Meeting Abstract June 2022

Time-resolved 2D-temperature monitoring on RPE explants during laser irradiation by means of a fluorescent dye

Ralf Brinkmann; Xi Zhang; leonie Hoffmann; Eric Seifert; Mario Mordmüller; Dirk Theisen-Kunde; Madoka Suzuki; Yoko Miura

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3801 – F0222. doi:

ARVO Annual Meeting Abstract June 2022

Improved Accuracy in Retinal Laser Therapy by Real-Time Temperature Control

Claus von der Burchard; Christopher Kren; Veit Danicke; Jan-Erik Fleger; Mario Mordmüller; Sebastian Wittmeier; Dirk Theisen-Kunde; Johann Roider; Ralf Brinkmann

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3800 – F0221. doi:

ARVO Annual Meeting Abstract June 2022

Real-Time Optical Coherence Tomography Controlled Microsecond Laser Retinal Microsurgery: First In-vivo Results

Christian Burri; Sami Al-Nawaiseh; André Schulz; Philip Wakili; Gerardo Farese; Peter Szurman; Simon Salzmann; Ralf Brinkmann; Boris Povazay; Christoph Meier; Martin Frenz; Boris V. Stanzel

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3796 – F0217. doi:

ARVO Annual Meeting Abstract June 2022

Short-term follow up after Large-Area RPE Removal by Microsecond Laser followed by hiPS-RPE suspension transplantation in rabbits

Sami Al-Nawaiseh; Christian Burri; André Schulz; Philip Wakili; Gerardo Farese; Christina Kroetz; Simon Salzmann; Brinkmann Ralf; Sylvia Jane Gasparini; Boris Povazay; Martin Frenz; Peter Szurman; Marius Ader; Boris V. Stanzel

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4509 – F0296. doi:

ARVO Annual Meeting Abstract June 2021

Real-time temperature controlled cw-laser treatment in rabbits

Jan-Erik Fleger; Claus von der Burchard; Christopher Kren; Mario Mordmüller; Dirk Theisen-Kunde; Veit Danicke; Hossam Abbas; Ralf Brinkmann; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3309. doi:

ARVO Annual Meeting Abstract June 2021

Automatic Temperature Control for Retinal Laser Exposures

Ralf Brinkmann; Christopher Kren; Veit Danicke; Ahmed Almashharawi; Mario Mordmüller; Dirk Theisen-Kunde; Yoko Miura; Claus von der Burchard; Johann Roider; Hossam Abbas

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3308. doi:

ARVO Annual Meeting Abstract June 2021

Fluorescence Lifetime Imaging Ophthalmoscopy of mouse models of age-related macular degeneration

Yoko Miura; Britta Lewke; Erdal Tan Ishizuka; Svenja Rebecca Sonntag; Eric Seifert; Salvatore Grisanti; Ralf Brinkmann

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):365. doi:

ARVO Annual Meeting Abstract June 2021

Impact of laser-induced damage on the fluorescence lifetimes at the rabbit fundus

Svenja Rebecca Sonntag; Eric Seifert; Maximilian Hamann; Britta Lewke; Dirk Theisen-Kunde; Ralf Brinkmann; Salvatore Grisanti; Yoko Miura

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):359. doi:

ARVO Annual Meeting Abstract June 2021

Autophagy inhibition-induced alterations of energy metabolism and fluorescence lifetime of the retinal pigment epithelium ex vivo

Richard Foerster; Erdal Tan Ishizuka; Kensuke Shima; Britta Lewke; Svenja Rebecca Sonntag; Jan Rupp; Ralf Brinkmann; Salvatore Grisanti; Yoko Miura

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2219. doi:

Retina March 2021

Investigations on Retinal Pigment Epithelial Damage at Laser Irradiation in the Lower Microsecond Time Regime

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Eric Seifert; Svenja Rebecca Sonntag; Philipp Kleingarn; Dirk Theisen-Kunde; Salvatore Grisanti; Reginald Birngruber; Yoko Miura; Ralf Brinkmann
TAGS: lasers, pigment, epithelium, cell injury
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):32. doi: https://doi.org/10.1167/iovs.62.3.32

ARVO Annual Meeting Abstract June 2020

Inflammatory Processes Following Thermal Stimulation of the Retina (TSR) and Selective Retina Therapy (SRT) in AMD Mouse Models

Jan Tode; Elisabeth Richert; Claus von der Burchard; Ralf Brinkmann; Alexa Klettner; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1352. doi:

ARVO Annual Meeting Abstract June 2020

Automatic Temperature Controlled Retinal Laser Therapies

Ralf Brinkmann; Hossam Abbas; Christopher Kren; Veit Danicke; Dirk Theisen-Kunde; Yoko Miura; Jan Tode; Claus von der Burchard; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1354. doi:

Articles December 2019

Towards Automatically Controlled Dosing for Selective Laser Trabeculoplasty

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Katharina Bliedtner; Eric Seifert; Ralf Brinkmann
TAGS: laser trabeculoplasty, lasers, modified barium swallow, optics, feedback, sensitivity and specificity, datasets, eye, wheelchair ramps, suidae
Trans. Vis. Sci. Tech.. 2019; 8(6):24. doi: https://doi.org/10.1167/tvst.8.6.24

Articles November 2019

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models

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Jan Tode; Elisabeth Richert; Stefan Koinzer; Alexa Klettner; Claus von der Burchard; Ralf Brinkmann; Ralph Lucius; Johann Roider
TAGS: age-related macular degeneration, biological response modifiers, eye, mice, retina, bruch's basal membrane, retinal pigment epithelium, pathology, apolipoprotein e
Trans. Vis. Sci. Tech.. 2019; 8(6):11. doi: https://doi.org/10.1167/tvst.8.6.11

Articles September 2019

Fluorescence Lifetime Imaging Ophthalmoscopy of the Retinal Pigment Epithelium During Wound Healing After Laser Irradiation

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Alessa Hutfilz; Svenja Rebecca Sonntag; Britta Lewke; Dirk Theisen-Kunde; Salvatore Grisanti; Ralf Brinkmann; Yoko Miura
TAGS: diagnostic imaging, fluorescence, lasers, ophthalmoscopy, wound healing, retinal pigment epithelium
Trans. Vis. Sci. Tech.. 2019; 8(5):12. doi: https://doi.org/10.1167/tvst.8.5.12

ARVO Annual Meeting Abstract July 2019

Sublethal hyperthermia on retinal pigment epithelium - possible role of heat shock protein 70 and influence of the inhibition of vascular endothelial growth factor-mediated signaling

Yoko Miura; Katharina Kern; Ralf Brinkmann

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3672. doi:

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Metabolic analysis of serum deprived ARPE-19 cells -implications for cellular metabolic changes in age-related macular degeneration

Fluorescence lifetime of ex-vivo retinal pigment epithelium in the state of enhanced mitochondrial uncoupling

Towards thermal stimulation of the retina, RPE and choroid by temperature-controlled laser exposure

Comparison between continuous wave and 10 kHz pulsed laser irradiation with regard to thermal damage on ex-vivo RPE explants

Time-resolved 2D-temperature monitoring on RPE explants during laser irradiation by means of a fluorescent dye

Improved Accuracy in Retinal Laser Therapy by Real-Time Temperature Control

Real-Time Optical Coherence Tomography Controlled Microsecond Laser Retinal Microsurgery: First In-vivo Results

Short-term follow up after Large-Area RPE Removal by Microsecond Laser followed by hiPS-RPE suspension transplantation in rabbits

Real-time temperature controlled cw-laser treatment in rabbits

Automatic Temperature Control for Retinal Laser Exposures

Fluorescence Lifetime Imaging Ophthalmoscopy of mouse models of age-related macular degeneration

Impact of laser-induced damage on the fluorescence lifetimes at the rabbit fundus

Autophagy inhibition-induced alterations of energy metabolism and fluorescence lifetime of the retinal pigment epithelium ex vivo

Investigations on Retinal Pigment Epithelial Damage at Laser Irradiation in the Lower Microsecond Time Regime

Inflammatory Processes Following Thermal Stimulation of the Retina (TSR) and Selective Retina Therapy (SRT) in AMD Mouse Models

Automatic Temperature Controlled Retinal Laser Therapies

Towards Automatically Controlled Dosing for Selective Laser Trabeculoplasty

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models

Fluorescence Lifetime Imaging Ophthalmoscopy of the Retinal Pigment Epithelium During Wound Healing After Laser Irradiation

Sublethal hyperthermia on retinal pigment epithelium - possible role of heat shock protein 70 and influence of the inhibition of vascular endothelial growth factor-mediated signaling

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