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ARVO Annual Meeting Abstract June 2024

Serine and glycine physiology reversibly modulate retinal and peripheral nerve function

Marin Gantner; Regis Fallon; Caleb Bates; Esther Lim; Yoichiro Ideguchi; Takayuki Nagasaki; Michal Handzlik; Roberto Bonelli; Rando Allikmets; Martina Wallace; Christian Metallo; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):436.

ARVO Annual Meeting Abstract June 2024

Safety, Tolerability, and Efficacy of Tinlarebant from the 24-Month Phase 2 study in Adolescent Patients Affected by Stargardt Disease

John R Grigg; Fred Chen; Ta-Ching Chen; Robyn V Jamieson; Hendrik P Scholl; Michel Michaelides; Jana Zernant; Rando Allikmets; Quan Dong Nguyen; Nathan L Mata

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1026.

ARVO Annual Meeting Abstract June 2023

Genotype is a Significant Factor in Determining the Measurability of Atrophic Lesions in ABCA4 disease

Winston Lee; PEI-YIN SU; Jana Zernant; Stephen Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5409.

ARVO Annual Meeting Abstract June 2023

New trans -modifier genes in the most common monogenic eye disorder, ABCA4/Stargardt disease.

Jana Zernant; Winston Lee; Takayuki Nagasaki; PEI-YIN SU; Stephen H. Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2798.

ARVO Annual Meeting Abstract June 2023

The Glycine Cleavage System in Retinal Metabolism and Disease

Caleb Bates; Esther Lim; Regis Fallon; Takayuki Nagasaki; Rando Allikmets; Martina Wallace; Christian M Metallo; Martin Friedlander; Marin Gantner

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3510.

Retina May 2023

Monitoring Lesion Area Progression in Stargardt Disease: A Comparison of En Face Optical Coherence Tomography and Fundus Autofluorescence

PDF

Vivienne C. Greenstein; David S. Castillejos; Stephen H. Tsang; Winston Lee; Janet R. Sparrow; Rando Allikmets; David G. Birch; Donald C. Hood
TAGS: face, fundus autofluorescence imaging, optical coherence tomography, stargardt's disease
Trans. Vis. Sci. Tech.. 2023; 12(5):2. https://doi.org/10.1167/tvst.12.5.2

Includes: Supplemental Content

Retina April 2023

Insights Into PROM1 -Macular Disease Using Multimodal Imaging

PDF

Maarjaliis Paavo; Winston Lee; Rait Parmann; Jose Ronaldo Lima de Carvalho, Jr.; Jana Zernant; Stephen H. Tsang; Rando Allikmets; Janet R. Sparrow
TAGS: eye, multimodal imaging, retinal imaging, spectral domain-optical coherence tomography, macula lutea
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):27. https://doi.org/10.1167/iovs.64.4.27

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2022

A common haplotype in the PRPH2 gene modifies Stargardt/ABCA4 disease.

Jana Zernant; Winston Lee; Jun Wang; KERRY GOETZ; Ehsan Ullah; Takayuki Nagasaki; PEI-YIN SU; Gerald A Fishman; Stephen H Tsang; Santa J Tumminia; Brian Brooks; Robert B Hufnagel; Rui Chen; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1596 – A0385.

ARVO Annual Meeting Abstract June 2022

Patient iPSC-RPE implicate mitochondrial defects in Macular Telangiectasia

Sarah Giles; Brendan Ansell; Sarah Harkins-Perry; Martina Wallace; Marin Gantner; Regis Fallon; Alec Johnson; Barbara Hart; Melanie Bahlo; Rando Allikmets; Christian Metallo; Paul S Bernstein; Martin Friedlander; Kevin Thomas Eade

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2449 – F0393.

ARVO Annual Meeting Abstract June 2022

Vitelliform foveomacular lesions in ABCA4 disease: A phenotypic expansion and longitudinal study

PEI-YIN SU; Winston Lee; Jana Zernant; Takayuki Nagasaki; Stephen H Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3752 – F0173.

ARVO Annual Meeting Abstract June 2022

Identifying critical diagnostic features that distinguish ABCA4 disease from its Mendelian phenocopies

Winston Lee; Jana Zernant; Takayuki Nagasaki; Stephen H Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3745 – F0166.

Articles January 2022

Comparisons Among Optical Coherence Tomography and Fundus Autofluorescence Modalities as Measurements of Atrophy in ABCA4 -Associated Disease

PDF

Rait Parmann; Stephen H. Tsang; Jana Zernant; Rando Allikmets; Vivienne C. Greenstein; Janet R. Sparrow
TAGS: abca4 gene, atrophy, fundus autofluorescence imaging, optical coherence tomography, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2022; 11(1):36. https://doi.org/10.1167/tvst.11.1.36

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Clinical and Genetics Characterization of Hypomorphic Variants in Stargardt disease

Winston Lee; Jana Zernant; Takayuki Nagasaki; Gerald A Fishman; Stephen H Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2171.

ARVO Annual Meeting Abstract June 2021

Characterization of Stargardt disease patient-derived human retinal organoids harboring the p.Gly1961Glu mutation in the ABCA4 gene

PEI-YIN SU; Jen-Zen Chuang; Winston Lee; Jana Zernant; Stephen H Tsang; Takayuki Nagasaki; Ching-Hwa Sung; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2595.

ARVO Annual Meeting Abstract June 2021

Uniocular peripheral retinal laser stabilizes AMD visual outcomes binocularly

Danny H.- Kauffmann Jokl; R Theodore Smith; Rando Allikmets; Sankha Amarakoon; weijia fan; mihai busuioc; Suzanne Yzer; jan van meurs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):280.

ARVO Annual Meeting Abstract June 2021

Shared Features in Retinal Diseases with Primary Involvement of Retinal Pigment Epithelium

Rait Parmann; Ruben Jauregui; Rando Allikmets; Stanley Chang; Stephen H Tsang; Janet R Sparrow

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1904.

Perspective June 2021

Shared Features in Retinal Disorders With Involvement of Retinal Pigment Epithelium

PDF

Janet R. Sparrow; Rait Parmann; Stephen H. Tsang; Rando Allikmets; Stanley Chang; Ruben Jauregui
TAGS: retinal diseases, retinal pigment epithelium, spectral domain-optical coherence tomography, mutation, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):15. https://doi.org/10.1167/iovs.62.7.15

Articles January 2021

Retinal Pigment Epithelium Atrophy in Recessive Stargardt Disease as Measured by Short-Wavelength and Near-Infrared Autofluorescence

PDF

Ruben Jauregui; Yan Nuzbrokh; Pei-Yin Su; Jana Zernant; Rando Allikmets; Stephen H. Tsang; Janet R. Sparrow
TAGS: autofluorescence, chorioretinal atrophy, hypertrophy, retinal pigment epithelium atrophy, stargardt's disease, atrophy, diagnostic imaging, phenotype
Trans. Vis. Sci. Tech.. 2021; 10(1):3. https://doi.org/10.1167/tvst.10.1.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Clinical Characterization of an Extremely Mild, Late-Onset Phenotype of ABCA4 Disease

PEI-YIN SU; Winston Lee; Jana Zernant; Stephen Tsang; Janet R Sparrow; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1051.

ARVO Annual Meeting Abstract June 2020

Do Mutations in ABCA4 Really Cause Retinitis Pigmentosa?

Winston Lee; Jana Zernant; Stephen Tsang; Janet R Sparrow; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1052.

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Serine and glycine physiology reversibly modulate retinal and peripheral nerve function

Safety, Tolerability, and Efficacy of Tinlarebant from the 24-Month Phase 2 study in Adolescent Patients Affected by Stargardt Disease

Genotype is a Significant Factor in Determining the Measurability of Atrophic Lesions in ABCA4 disease

New trans -modifier genes in the most common monogenic eye disorder, ABCA4/Stargardt disease.

The Glycine Cleavage System in Retinal Metabolism and Disease

Monitoring Lesion Area Progression in Stargardt Disease: A Comparison of En Face Optical Coherence Tomography and Fundus Autofluorescence

Insights Into PROM1 -Macular Disease Using Multimodal Imaging

A common haplotype in the PRPH2 gene modifies Stargardt/ABCA4 disease.

Patient iPSC-RPE implicate mitochondrial defects in Macular Telangiectasia

Vitelliform foveomacular lesions in ABCA4 disease: A phenotypic expansion and longitudinal study

Identifying critical diagnostic features that distinguish ABCA4 disease from its Mendelian phenocopies

Comparisons Among Optical Coherence Tomography and Fundus Autofluorescence Modalities as Measurements of Atrophy in ABCA4 -Associated Disease

Clinical and Genetics Characterization of Hypomorphic Variants in Stargardt disease

Characterization of Stargardt disease patient-derived human retinal organoids harboring the p.Gly1961Glu mutation in the ABCA4 gene

Uniocular peripheral retinal laser stabilizes AMD visual outcomes binocularly

Shared Features in Retinal Diseases with Primary Involvement of Retinal Pigment Epithelium

Shared Features in Retinal Disorders With Involvement of Retinal Pigment Epithelium

Retinal Pigment Epithelium Atrophy in Recessive Stargardt Disease as Measured by Short-Wavelength and Near-Infrared Autofluorescence

Clinical Characterization of an Extremely Mild, Late-Onset Phenotype of ABCA4 Disease

Do Mutations in ABCA4 Really Cause Retinitis Pigmentosa?

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